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The map label for this gene is gap [H]

Identifier: 188586950

GI number: 188586950

Start: 2490110

End: 2491117

Strand: Reverse

Name: gap [H]

Synonym: Nther_2342

Alternate gene names: 188586950

Gene position: 2491117-2490110 (Counterclockwise)

Preceding gene: 188586951

Following gene: 188586949

Centisome position: 78.69

GC content: 41.27

Gene sequence:

>1008_bases
ATGACTGTGAGAGTAGCCATTAATGGTTTTGGAAGAATTGGACGTCATTGCCTGCGAAATAGTTTGAATAACAAGCAGGT
AGAAGTAGTGGCAGTAAATGACCTGGCAGATATCAATACTCTCAGCCACTTATTCAAGTACGATTCCCTGTACGGCCCAT
TCCAAGGGGAATTAAAGACTGAGGGTGATGAACTTGTCGTCGACGGAAATAGGGTGAAAGTATTAAATGAAAAGGAACCT
GAAAAATTGCCTTGGGATCAGCTGGATGTGGATATAGTTTTGGAAGCTACAGGGATTTTCAGAGATCGGGATGGAGCTAA
ACGTCATCTAGACGCTGGGGCTGATAGAGTTATTATTACTGCACCAGCCAAAAATGAAGATATTACAATTGTAATGGGAG
TTAACGAAAATGATTATAATCCCAATGAGCATCGAATTATATCCAAAGCCAGTTGTACCACAAATTGCGTAGCTCCAGTT
GTCAAGGTGCTTGATGAAGCTTTCGGCATTGAAAAAGCTTTAATGACTACTGTCCACTCTTATACTAACGATCAACAGCT
TTTAGATTTACCACATAAGGATTTACGTCGAGGAAGAGCGGCGGCTGAATCTATTATCCCAACAACTACTGGTGCTGCAA
AGGCAGTGTCCTCAGTGCTTCCTCAATTAGAAGGAAAAATCGATGGTTATGCCATGAGGGTTCCCACACCTACTGTGAGT
ATTGTTGATTTGGCTTGTACTGTAAATAAAGACACAGTAACTCGGGATCAAGTCAATGAGAAATTTAAAGAGGCTAGTGA
GGAAGAATTAGATGGCATCTTGGGGTATAGTGATGAACCCTTAGTATCTATGGATTATAAGGGAAGTACTGAATCTGCGG
TAGTAGATGCCATTTCGACTATGGTTGTTCAGGACAACATGGTTAAAGCTGTGGCCTGGTATGATAATGAATGGGCTTAT
GCCCGACGAGTAATTGACTTAGCCGCATATATTGGAAACAACAGTTAA

Upstream 100 bases:

>100_bases
TACCTACTCAGGGTCGAATTTTGGACTACGGGGCAAACATTGACCCGCAAGTTATTAAAAAGTCTTTGTAAGGATATAAT
AATTTTGAGGAGGGATTAAC

Downstream 100 bases:

>100_bases
TAAACATCAGATAAGTCAGTTTGTAAGCCATTCCGGATTCAATTTTACTTCCGGGATGGCTTTTTTTTGGTTTTAGACTG
TATTAAAGTTGGATGTTGTC

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MTVRVAINGFGRIGRHCLRNSLNNKQVEVVAVNDLADINTLSHLFKYDSLYGPFQGELKTEGDELVVDGNRVKVLNEKEP
EKLPWDQLDVDIVLEATGIFRDRDGAKRHLDAGADRVIITAPAKNEDITIVMGVNENDYNPNEHRIISKASCTTNCVAPV
VKVLDEAFGIEKALMTTVHSYTNDQQLLDLPHKDLRRGRAAAESIIPTTTGAAKAVSSVLPQLEGKIDGYAMRVPTPTVS
IVDLACTVNKDTVTRDQVNEKFKEASEEELDGILGYSDEPLVSMDYKGSTESAVVDAISTMVVQDNMVKAVAWYDNEWAY
ARRVIDLAAYIGNNS

Sequences:

>Translated_335_residues
MTVRVAINGFGRIGRHCLRNSLNNKQVEVVAVNDLADINTLSHLFKYDSLYGPFQGELKTEGDELVVDGNRVKVLNEKEP
EKLPWDQLDVDIVLEATGIFRDRDGAKRHLDAGADRVIITAPAKNEDITIVMGVNENDYNPNEHRIISKASCTTNCVAPV
VKVLDEAFGIEKALMTTVHSYTNDQQLLDLPHKDLRRGRAAAESIIPTTTGAAKAVSSVLPQLEGKIDGYAMRVPTPTVS
IVDLACTVNKDTVTRDQVNEKFKEASEEELDGILGYSDEPLVSMDYKGSTESAVVDAISTMVVQDNMVKAVAWYDNEWAY
ARRVIDLAAYIGNNS
>Mature_334_residues
TVRVAINGFGRIGRHCLRNSLNNKQVEVVAVNDLADINTLSHLFKYDSLYGPFQGELKTEGDELVVDGNRVKVLNEKEPE
KLPWDQLDVDIVLEATGIFRDRDGAKRHLDAGADRVIITAPAKNEDITIVMGVNENDYNPNEHRIISKASCTTNCVAPVV
KVLDEAFGIEKALMTTVHSYTNDQQLLDLPHKDLRRGRAAAESIIPTTTGAAKAVSSVLPQLEGKIDGYAMRVPTPTVSI
VDLACTVNKDTVTRDQVNEKFKEASEEELDGILGYSDEPLVSMDYKGSTESAVVDAISTMVVQDNMVKAVAWYDNEWAYA
RRVIDLAAYIGNNS

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=329, Percent_Identity=47.112462006079, Blast_Score=310, Evalue=8e-85,
Organism=Homo sapiens, GI7669492, Length=331, Percent_Identity=45.619335347432, Blast_Score=308, Evalue=5e-84,
Organism=Escherichia coli, GI1788079, Length=332, Percent_Identity=45.7831325301205, Blast_Score=319, Evalue=2e-88,
Organism=Escherichia coli, GI1789295, Length=330, Percent_Identity=44.2424242424242, Blast_Score=300, Evalue=9e-83,
Organism=Caenorhabditis elegans, GI17534677, Length=334, Percent_Identity=44.6107784431138, Blast_Score=293, Evalue=1e-79,
Organism=Caenorhabditis elegans, GI17534679, Length=334, Percent_Identity=44.6107784431138, Blast_Score=291, Evalue=3e-79,
Organism=Caenorhabditis elegans, GI32566163, Length=338, Percent_Identity=43.7869822485207, Blast_Score=285, Evalue=3e-77,
Organism=Caenorhabditis elegans, GI17568413, Length=338, Percent_Identity=43.7869822485207, Blast_Score=285, Evalue=3e-77,
Organism=Saccharomyces cerevisiae, GI6322468, Length=331, Percent_Identity=48.9425981873112, Blast_Score=333, Evalue=2e-92,
Organism=Saccharomyces cerevisiae, GI6321631, Length=331, Percent_Identity=48.3383685800604, Blast_Score=327, Evalue=1e-90,
Organism=Saccharomyces cerevisiae, GI6322409, Length=331, Percent_Identity=45.9214501510574, Blast_Score=321, Evalue=8e-89,
Organism=Drosophila melanogaster, GI85725000, Length=330, Percent_Identity=46.969696969697, Blast_Score=302, Evalue=2e-82,
Organism=Drosophila melanogaster, GI22023983, Length=330, Percent_Identity=46.969696969697, Blast_Score=302, Evalue=2e-82,
Organism=Drosophila melanogaster, GI17933600, Length=330, Percent_Identity=46.0606060606061, Blast_Score=299, Evalue=2e-81,
Organism=Drosophila melanogaster, GI18110149, Length=330, Percent_Identity=46.0606060606061, Blast_Score=299, Evalue=2e-81,
Organism=Drosophila melanogaster, GI19922412, Length=328, Percent_Identity=44.2073170731707, Blast_Score=282, Evalue=2e-76,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36881; Mature: 36750

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00047 HISTONE_H4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRVAINGFGRIGRHCLRNSLNNKQVEVVAVNDLADINTLSHLFKYDSLYGPFQGELKT
CEEEEEECCCHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCEEC
EGDELVVDGNRVKVLNEKEPEKLPWDQLDVDIVLEATGIFRDRDGAKRHLDAGADRVIIT
CCCEEEECCCEEEEECCCCCCCCCCCCCCEEEEEEECCCEECCCCHHHHHCCCCCEEEEE
APAKNEDITIVMGVNENDYNPNEHRIISKASCTTNCVAPVVKVLDEAFGIEKALMTTVHS
CCCCCCCEEEEEECCCCCCCCCHHEEEEECCCCHHHHHHHHHHHHHHHCHHHHHHHHHHH
YTNDQQLLDLPHKDLRRGRAAAESIIPTTTGAAKAVSSVLPQLEGKIDGYAMRVPTPTVS
CCCCHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCEE
IVDLACTVNKDTVTRDQVNEKFKEASEEELDGILGYSDEPLVSMDYKGSTESAVVDAIST
EEEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHH
MVVQDNMVKAVAWYDNEWAYARRVIDLAAYIGNNS
HHHHCCCEEEEEEECCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TVRVAINGFGRIGRHCLRNSLNNKQVEVVAVNDLADINTLSHLFKYDSLYGPFQGELKT
EEEEEECCCHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCEEC
EGDELVVDGNRVKVLNEKEPEKLPWDQLDVDIVLEATGIFRDRDGAKRHLDAGADRVIIT
CCCEEEECCCEEEEECCCCCCCCCCCCCCEEEEEEECCCEECCCCHHHHHCCCCCEEEEE
APAKNEDITIVMGVNENDYNPNEHRIISKASCTTNCVAPVVKVLDEAFGIEKALMTTVHS
CCCCCCCEEEEEECCCCCCCCCHHEEEEECCCCHHHHHHHHHHHHHHHCHHHHHHHHHHH
YTNDQQLLDLPHKDLRRGRAAAESIIPTTTGAAKAVSSVLPQLEGKIDGYAMRVPTPTVS
CCCCHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCEE
IVDLACTVNKDTVTRDQVNEKFKEASEEELDGILGYSDEPLVSMDYKGSTESAVVDAIST
EEEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHH
MVVQDNMVKAVAWYDNEWAYARRVIDLAAYIGNNS
HHHHCCCEEEEEEECCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2684782; 2227448; 2656407; 7408868; 193030; 3586018; 9175858 [H]