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The map label for this gene is yisQ [H]

Identifier: 188586951

GI number: 188586951

Start: 2491362

End: 2492756

Strand: Reverse

Name: yisQ [H]

Synonym: Nther_2343

Alternate gene names: 188586951

Gene position: 2492756-2491362 (Counterclockwise)

Preceding gene: 188586952

Following gene: 188586950

Centisome position: 78.75

GC content: 42.94

Gene sequence:

>1395_bases
ATGGCTAAGTCTACCATGACAAGAAGAGAACGTATTTTAGAGGGCAATCTTTTACACAGTGTCTGTTATTTGGCCTGGCC
CATTGTCTTGCAGTCGCTACTTCATGTGACCATGGGCATGGCAGATCTGCGCATGGTAAATCACCTGGGTCATGAAGCTA
TTGCTGCAGTGGGCATTGGCCGACAGGTAATTATGATTATCCTGGTAATGGTTTTGGCTATTCAGGCAGGAGCCGTTGCT
GTTGTCGCCCGAAAACTAGGCGAGAAAAATTATGAACATGCAGAAAGTGCTGCTGGGCAAGCAATGACCCTGGTATTATT
ATTTGCCCTTGTTATGACTCCAGTTGGGATTCTTAGTTCTCGTTTGCTTCTGACATTAATGGGAGCCAAACCAGGAGTTA
TGGCCCTGGGAGTTCCTTATATGCAAGTGTTCTTTCTGGGGATAGTTTTCTTCATGGGAAACTTTATGTGTAAAGCAATT
TTTCACGGATTGGGAGACACTAGAACTCCTCTTTACATTAATATAGCCGTTAATGGGATAAATCTGATAGGTAACTTTTT
CTTGATATACGGATTATGGTTTTTCCCAGAACTGGGTGTGATTGGTGCAGCTGTAGCAAGCGCATTCAGCAGGTTAGTTG
GTACAGTTCTGGGTATTGTTGTTTTAAATAAAGGACACTATGCTATCAGAATACGTCTGAGCCATGTATTGAAATTTTCT
TTCGAGGAAATTAAGGAAATACTGCGTATTGGGATGCCTACCGCTTTTCAGGGTATGAGCCGCAATATCAGTACTTTACT
TCTTGTCAGCATGATCACAAGGACTGCAGCCGGTGGTTTTGCTGCAGCCGCTTTTCCAGTGGGTATGAAAGTAAATCAAT
TTGCTATTATGCCGGGTATTGCCATAGGTCAGGCAACTACTACCATGGTTGGTATGAACTTAGGTAATGAAAACCCTAAA
AGGGCGGAGCAATGTGGTTGGACTGCAAGTAGGGTTGGCAGCATTTTAATGTCTGCCATTGCCCTGATTAATTTTATTTT
TGCTCCTCAAATCATGAGTTTTTTTGCAGAAGAATCTGAAGTTATAGAGATCGGCACTGCTTTTATTAGAATCATTGCCG
TGGCAGAACCTTTCCATGCTTTGGGTGTGATTTTATCCAAAGGTATGCAAGGAGCGGGTTATACCCTAGTGCCCTTTTAT
TTGACTGTGATTTCTTGGTTGGGAATTCGAGTTCCCTTGGCTTATCTTTTGGCCTTTCCTTTAAACCTTCAGTCAACTGG
TGTCTGGATAAGCATGAATGCTACCTTTATCCTACAGGCCGTCTTGGTAGCAACAGCTTTTAAGCGAGGTACCTGGAAAG
AGGCCAAATTAAAAGCCTATTCTACAGGCTCCTGA

Upstream 100 bases:

>100_bases
ACCTTTAGCTTTGTAATATTTTGTTTTGACATCATGACATTTGTCATGATTAAATATATTTAGGATATCGAAATAATTTT
TTGAAACGGGCGGGTTCTAT

Downstream 100 bases:

>100_bases
TTTTACGGCTCATAAATAACTTAAAATGATACCCCTGGCTTTTTTTCGGAAAATTTGATATAATTACCAGTGAAATAAAT
TCGGGTCTATAATAAGTTTA

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MAKSTMTRRERILEGNLLHSVCYLAWPIVLQSLLHVTMGMADLRMVNHLGHEAIAAVGIGRQVIMIILVMVLAIQAGAVA
VVARKLGEKNYEHAESAAGQAMTLVLLFALVMTPVGILSSRLLLTLMGAKPGVMALGVPYMQVFFLGIVFFMGNFMCKAI
FHGLGDTRTPLYINIAVNGINLIGNFFLIYGLWFFPELGVIGAAVASAFSRLVGTVLGIVVLNKGHYAIRIRLSHVLKFS
FEEIKEILRIGMPTAFQGMSRNISTLLLVSMITRTAAGGFAAAAFPVGMKVNQFAIMPGIAIGQATTTMVGMNLGNENPK
RAEQCGWTASRVGSILMSAIALINFIFAPQIMSFFAEESEVIEIGTAFIRIIAVAEPFHALGVILSKGMQGAGYTLVPFY
LTVISWLGIRVPLAYLLAFPLNLQSTGVWISMNATFILQAVLVATAFKRGTWKEAKLKAYSTGS

Sequences:

>Translated_464_residues
MAKSTMTRRERILEGNLLHSVCYLAWPIVLQSLLHVTMGMADLRMVNHLGHEAIAAVGIGRQVIMIILVMVLAIQAGAVA
VVARKLGEKNYEHAESAAGQAMTLVLLFALVMTPVGILSSRLLLTLMGAKPGVMALGVPYMQVFFLGIVFFMGNFMCKAI
FHGLGDTRTPLYINIAVNGINLIGNFFLIYGLWFFPELGVIGAAVASAFSRLVGTVLGIVVLNKGHYAIRIRLSHVLKFS
FEEIKEILRIGMPTAFQGMSRNISTLLLVSMITRTAAGGFAAAAFPVGMKVNQFAIMPGIAIGQATTTMVGMNLGNENPK
RAEQCGWTASRVGSILMSAIALINFIFAPQIMSFFAEESEVIEIGTAFIRIIAVAEPFHALGVILSKGMQGAGYTLVPFY
LTVISWLGIRVPLAYLLAFPLNLQSTGVWISMNATFILQAVLVATAFKRGTWKEAKLKAYSTGS
>Mature_463_residues
AKSTMTRRERILEGNLLHSVCYLAWPIVLQSLLHVTMGMADLRMVNHLGHEAIAAVGIGRQVIMIILVMVLAIQAGAVAV
VARKLGEKNYEHAESAAGQAMTLVLLFALVMTPVGILSSRLLLTLMGAKPGVMALGVPYMQVFFLGIVFFMGNFMCKAIF
HGLGDTRTPLYINIAVNGINLIGNFFLIYGLWFFPELGVIGAAVASAFSRLVGTVLGIVVLNKGHYAIRIRLSHVLKFSF
EEIKEILRIGMPTAFQGMSRNISTLLLVSMITRTAAGGFAAAAFPVGMKVNQFAIMPGIAIGQATTTMVGMNLGNENPKR
AEQCGWTASRVGSILMSAIALINFIFAPQIMSFFAEESEVIEIGTAFIRIIAVAEPFHALGVILSKGMQGAGYTLVPFYL
TVISWLGIRVPLAYLLAFPLNLQSTGVWISMNATFILQAVLVATAFKRGTWKEAKLKAYSTGS

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=442, Percent_Identity=28.9592760180996, Blast_Score=146, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 50127; Mature: 49996

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSTMTRRERILEGNLLHSVCYLAWPIVLQSLLHVTMGMADLRMVNHLGHEAIAAVGIG
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCC
RQVIMIILVMVLAIQAGAVAVVARKLGEKNYEHAESAAGQAMTLVLLFALVMTPVGILSS
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
RLLLTLMGAKPGVMALGVPYMQVFFLGIVFFMGNFMCKAIFHGLGDTRTPLYINIAVNGI
HHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCH
NLIGNFFLIYGLWFFPELGVIGAAVASAFSRLVGTVLGIVVLNKGHYAIRIRLSHVLKFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHH
FEEIKEILRIGMPTAFQGMSRNISTLLLVSMITRTAAGGFAAAAFPVGMKVNQFAIMPGI
HHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCEEECCCC
AIGQATTTMVGMNLGNENPKRAEQCGWTASRVGSILMSAIALINFIFAPQIMSFFAEESE
EECCHHHHHEEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
VIEIGTAFIRIIAVAEPFHALGVILSKGMQGAGYTLVPFYLTVISWLGIRVPLAYLLAFP
HHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
LNLQSTGVWISMNATFILQAVLVATAFKRGTWKEAKLKAYSTGS
CCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCC
>Mature Secondary Structure 
AKSTMTRRERILEGNLLHSVCYLAWPIVLQSLLHVTMGMADLRMVNHLGHEAIAAVGIG
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCC
RQVIMIILVMVLAIQAGAVAVVARKLGEKNYEHAESAAGQAMTLVLLFALVMTPVGILSS
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
RLLLTLMGAKPGVMALGVPYMQVFFLGIVFFMGNFMCKAIFHGLGDTRTPLYINIAVNGI
HHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCH
NLIGNFFLIYGLWFFPELGVIGAAVASAFSRLVGTVLGIVVLNKGHYAIRIRLSHVLKFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHH
FEEIKEILRIGMPTAFQGMSRNISTLLLVSMITRTAAGGFAAAAFPVGMKVNQFAIMPGI
HHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCEEECCCC
AIGQATTTMVGMNLGNENPKRAEQCGWTASRVGSILMSAIALINFIFAPQIMSFFAEESE
EECCHHHHHEEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
VIEIGTAFIRIIAVAEPFHALGVILSKGMQGAGYTLVPFYLTVISWLGIRVPLAYLLAFP
HHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
LNLQSTGVWISMNATFILQAVLVATAFKRGTWKEAKLKAYSTGS
CCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]