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The map label for this gene is mgm [H]

Identifier: 188586766

GI number: 188586766

Start: 2282487

End: 2284337

Strand: Reverse

Name: mgm [H]

Synonym: Nther_2157

Alternate gene names: 188586766

Gene position: 2284337-2282487 (Counterclockwise)

Preceding gene: 188586767

Following gene: 188586765

Centisome position: 72.16

GC content: 41.11

Gene sequence:

>1851_bases
ATGAGTAGTGAAAGGCCAAATACTAAGCGAATTATTCGTGAAGATATTGACAGAATAAGAGCTTATGAAAAGGCTTTTGA
TGTGGATATGCCCTATATTGGCGAGGACGGAGAAATTAAAAACTTGCCAGACCCATTTCCTAGAGAAGTTAATGGAGTAG
TTAGAAGCGGTTACCGCTTAACAGAACTAGGGAGACAGGCTGAAAAAGAGAAAATGCCAGTTATGAACCCAATTTTAGGC
AGGAATACAGCTGAAGAAACCTTCAAAGAATCCAAGATTATGTACGACAAAGCTGAAGAACTAGGCGTTCAAATGTTTCA
TTTCGTTCACTCTGAGGCCACTCGGCATATAGATCCTTTAGATGGAATAGAGTTGGTTGAACAGTCACGTGGTAAAGGTG
GAATTACACCTAAAGGTGAAAGAGAGTATGTTCAAATGGGTGGTGGAAGTGTCCATCCCATGAGGATAAATGCAACTGGG
GACACTCCTCATATTTCGATTTTGAATTCATTGATGGCAGGTTTTGATGGAACAGATATTGGACCAGTTATTCACGTTCA
TTTCGGAGGCCGAGGAATTCATGACTACAAGACTAAGGTGACTAACAGTTACAAAGCAATTCAAATTTGTGCAGAAAATA
ATATCTTTGTTCAATTGGATTCACACAAGCATGTAAATAATATTTTAGGTACTGACGGAATGGCCCTGGCCATGTGTTTA
TTATCCGAAGGTTTGGCAGTTAAAGCTGGGTTGGATAGAGCTTTAAGTGCTATTCAGATGAACGTAGGTGGTATCAACCT
GTTAGCTGATATAGCAGTAATGAAAGCATTTAAAGAGACGACCTGGAGTGAGTTTATTATCGTTGTACCTGAAACGTTCC
AGGATCCACCAGCAGATTTTAGGGCAGAGCAGGCTCACTTTGCTAGAATGGCAGTCAGTGCCAAATTGGGAGAAGCTAAC
TTTTACAGGCCTAAAGCAGCAGAATCAGTAGGTATTCCAACAGGCGAATCAATGTCAAAGGCCATTTGGGCATCTCAGAA
TGTCTTTGAGAGCATGTATCAAACTGAGATAAATGATCCCTTTATCGAGAAGAGAAAAGAAGAAATCCAAACAGAAGCCA
TGGCAGTACTATCAGCAGCTCTCAAAATGGATAGAATGTTATCGCCTGAAGAAATCACCGAAGAATTTTGGCAACAGTTT
GATTCAGAAGAGCTGATAGATCTTATTGTCACTGCTGGAAAGAGCGGAGTTCTAGATACACCAAGAGCAGGTGGATGGGA
TCTACAGAGATACGTAAAAACTCATAGGGATCAGGATGGAATACGCAGATATATTCCGGGTTGTACACCTCAAGGTGTAG
ATGAGCAGTATATGCCGATAGCGAAAGAAGATGTAGAACCACCTAAAGAAACTGAAGTCATCCACGATGAAAAAATAGTC
CTTGCTACAGTAGGCGCGGATGCCCATGTAATTGGTATAAACAAGGTTAAAGAAGCATGTGAAGAAGCCGGTTACGAAGT
TATTTTCTTAAGAGGAATGAACTTACCAGAGGCGGTAGCCGAAGTTGCTGCCGAAACCCAAGCGAAATTGGTGGGAGTCA
GTAATTTACTTGGTCTAGGTGGCTCATTGTATCCGCGAGTTGATCAAAGGCTAAGAGAACTTGGTTTAAGAGATGAAGTT
CACTTGATGGCCGGAGGCCGAATAGCGGAAAAAGAAGAGGAACACAAAGAGTACGAAGAAAGAATCGAAAAAGAAGGTCC
TGGCTTTTTAGGTGTAGATGTTTTCTTTGGACCTGGTAGTTCTTATGAAGAGATTGTAGATTGGATTAATACAAAACTCG
GCAATAAATAA

Upstream 100 bases:

>100_bases
TTCCAACTAGAGGAGCTATCACAAGTCACCATGGAAACACTGGAAGCCGGTGGACTGATCAACAAAGTCAAAATGATATT
AAATATAAGAGGTGATATGA

Downstream 100 bases:

>100_bases
GAAAAGAGATAAGGAACTGTTAAGTTATTAAATTCCTTCCGGTAACTATTTATCAATCGTTTCAAAGGCCGGAACTAAGG
AGGGGTTAGTGTGGATCAGG

Product: 2-methyleneglutarate mutase

Products: NA

Alternate protein names: Alpha-methyleneglutarate mutase [H]

Number of amino acids: Translated: 616; Mature: 615

Protein sequence:

>616_residues
MSSERPNTKRIIREDIDRIRAYEKAFDVDMPYIGEDGEIKNLPDPFPREVNGVVRSGYRLTELGRQAEKEKMPVMNPILG
RNTAEETFKESKIMYDKAEELGVQMFHFVHSEATRHIDPLDGIELVEQSRGKGGITPKGEREYVQMGGGSVHPMRINATG
DTPHISILNSLMAGFDGTDIGPVIHVHFGGRGIHDYKTKVTNSYKAIQICAENNIFVQLDSHKHVNNILGTDGMALAMCL
LSEGLAVKAGLDRALSAIQMNVGGINLLADIAVMKAFKETTWSEFIIVVPETFQDPPADFRAEQAHFARMAVSAKLGEAN
FYRPKAAESVGIPTGESMSKAIWASQNVFESMYQTEINDPFIEKRKEEIQTEAMAVLSAALKMDRMLSPEEITEEFWQQF
DSEELIDLIVTAGKSGVLDTPRAGGWDLQRYVKTHRDQDGIRRYIPGCTPQGVDEQYMPIAKEDVEPPKETEVIHDEKIV
LATVGADAHVIGINKVKEACEEAGYEVIFLRGMNLPEAVAEVAAETQAKLVGVSNLLGLGGSLYPRVDQRLRELGLRDEV
HLMAGGRIAEKEEEHKEYEERIEKEGPGFLGVDVFFGPGSSYEEIVDWINTKLGNK

Sequences:

>Translated_616_residues
MSSERPNTKRIIREDIDRIRAYEKAFDVDMPYIGEDGEIKNLPDPFPREVNGVVRSGYRLTELGRQAEKEKMPVMNPILG
RNTAEETFKESKIMYDKAEELGVQMFHFVHSEATRHIDPLDGIELVEQSRGKGGITPKGEREYVQMGGGSVHPMRINATG
DTPHISILNSLMAGFDGTDIGPVIHVHFGGRGIHDYKTKVTNSYKAIQICAENNIFVQLDSHKHVNNILGTDGMALAMCL
LSEGLAVKAGLDRALSAIQMNVGGINLLADIAVMKAFKETTWSEFIIVVPETFQDPPADFRAEQAHFARMAVSAKLGEAN
FYRPKAAESVGIPTGESMSKAIWASQNVFESMYQTEINDPFIEKRKEEIQTEAMAVLSAALKMDRMLSPEEITEEFWQQF
DSEELIDLIVTAGKSGVLDTPRAGGWDLQRYVKTHRDQDGIRRYIPGCTPQGVDEQYMPIAKEDVEPPKETEVIHDEKIV
LATVGADAHVIGINKVKEACEEAGYEVIFLRGMNLPEAVAEVAAETQAKLVGVSNLLGLGGSLYPRVDQRLRELGLRDEV
HLMAGGRIAEKEEEHKEYEERIEKEGPGFLGVDVFFGPGSSYEEIVDWINTKLGNK
>Mature_615_residues
SSERPNTKRIIREDIDRIRAYEKAFDVDMPYIGEDGEIKNLPDPFPREVNGVVRSGYRLTELGRQAEKEKMPVMNPILGR
NTAEETFKESKIMYDKAEELGVQMFHFVHSEATRHIDPLDGIELVEQSRGKGGITPKGEREYVQMGGGSVHPMRINATGD
TPHISILNSLMAGFDGTDIGPVIHVHFGGRGIHDYKTKVTNSYKAIQICAENNIFVQLDSHKHVNNILGTDGMALAMCLL
SEGLAVKAGLDRALSAIQMNVGGINLLADIAVMKAFKETTWSEFIIVVPETFQDPPADFRAEQAHFARMAVSAKLGEANF
YRPKAAESVGIPTGESMSKAIWASQNVFESMYQTEINDPFIEKRKEEIQTEAMAVLSAALKMDRMLSPEEITEEFWQQFD
SEELIDLIVTAGKSGVLDTPRAGGWDLQRYVKTHRDQDGIRRYIPGCTPQGVDEQYMPIAKEDVEPPKETEVIHDEKIVL
ATVGADAHVIGINKVKEACEEAGYEVIFLRGMNLPEAVAEVAAETQAKLVGVSNLLGLGGSLYPRVDQRLRELGLRDEVH
LMAGGRIAEKEEEHKEYEERIEKEGPGFLGVDVFFGPGSSYEEIVDWINTKLGNK

Specific function: Involved in the fermentation of nicotinate to ammonia, propionate, acetate and carbon dioxide [H]

COG id: COG2185

COG function: function code I; Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 B12-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006159
- InterPro:   IPR006158 [H]

Pfam domain/function: PF02310 B12-binding [H]

EC number: =5.4.99.4 [H]

Molecular weight: Translated: 68495; Mature: 68363

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSERPNTKRIIREDIDRIRAYEKAFDVDMPYIGEDGEIKNLPDPFPREVNGVVRSGYRL
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHH
TELGRQAEKEKMPVMNPILGRNTAEETFKESKIMYDKAEELGVQMFHFVHSEATRHIDPL
HHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DGIELVEQSRGKGGITPKGEREYVQMGGGSVHPMRINATGDTPHISILNSLMAGFDGTDI
HHHHHHHHCCCCCCCCCCCCCHHHCCCCCEECEEEEECCCCCCHHHHHHHHHHCCCCCCC
GPVIHVHFGGRGIHDYKTKVTNSYKAIQICAENNIFVQLDSHKHVNNILGTDGMALAMCL
CCEEEEEECCCCCCHHHHHHCCCCEEEEEEECCCEEEEECCCCHHHHHHCCCHHHHHHHH
LSEGLAVKAGLDRALSAIQMNVGGINLLADIAVMKAFKETTWSEFIIVVPETFQDPPADF
HHCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCH
RAEQAHFARMAVSAKLGEANFYRPKAAESVGIPTGESMSKAIWASQNVFESMYQTEINDP
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCH
FIEKRKEEIQTEAMAVLSAALKMDRMLSPEEITEEFWQQFDSEELIDLIVTAGKSGVLDT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC
PRAGGWDLQRYVKTHRDQDGIRRYIPGCTPQGVDEQYMPIAKEDVEPPKETEVIHDEKIV
CCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCEEE
LATVGADAHVIGINKVKEACEEAGYEVIFLRGMNLPEAVAEVAAETQAKLVGVSNLLGLG
EEEECCCEEEEEHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCC
GSLYPRVDQRLRELGLRDEVHLMAGGRIAEKEEEHKEYEERIEKEGPGFLGVDVFFGPGS
CCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCC
SYEEIVDWINTKLGNK
CHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSERPNTKRIIREDIDRIRAYEKAFDVDMPYIGEDGEIKNLPDPFPREVNGVVRSGYRL
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHH
TELGRQAEKEKMPVMNPILGRNTAEETFKESKIMYDKAEELGVQMFHFVHSEATRHIDPL
HHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DGIELVEQSRGKGGITPKGEREYVQMGGGSVHPMRINATGDTPHISILNSLMAGFDGTDI
HHHHHHHHCCCCCCCCCCCCCHHHCCCCCEECEEEEECCCCCCHHHHHHHHHHCCCCCCC
GPVIHVHFGGRGIHDYKTKVTNSYKAIQICAENNIFVQLDSHKHVNNILGTDGMALAMCL
CCEEEEEECCCCCCHHHHHHCCCCEEEEEEECCCEEEEECCCCHHHHHHCCCHHHHHHHH
LSEGLAVKAGLDRALSAIQMNVGGINLLADIAVMKAFKETTWSEFIIVVPETFQDPPADF
HHCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCH
RAEQAHFARMAVSAKLGEANFYRPKAAESVGIPTGESMSKAIWASQNVFESMYQTEINDP
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCH
FIEKRKEEIQTEAMAVLSAALKMDRMLSPEEITEEFWQQFDSEELIDLIVTAGKSGVLDT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC
PRAGGWDLQRYVKTHRDQDGIRRYIPGCTPQGVDEQYMPIAKEDVEPPKETEVIHDEKIV
CCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCEEE
LATVGADAHVIGINKVKEACEEAGYEVIFLRGMNLPEAVAEVAAETQAKLVGVSNLLGLG
EEEECCCEEEEEHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCC
GSLYPRVDQRLRELGLRDEVHLMAGGRIAEKEEEHKEYEERIEKEGPGFLGVDVFFGPGS
CCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCC
SYEEIVDWINTKLGNK
CHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8168499 [H]