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The map label for this gene is pgiA [H]

Identifier: 188586613

GI number: 188586613

Start: 2110997

End: 2112337

Strand: Reverse

Name: pgiA [H]

Synonym: Nther_2003

Alternate gene names: 188586613

Gene position: 2112337-2110997 (Counterclockwise)

Preceding gene: 188586614

Following gene: 188586612

Centisome position: 66.73

GC content: 38.7

Gene sequence:

>1341_bases
ATGAAAGAGTATCAATTAGCAGTTGAAAGAATTGAGGTGAATTGGAACTATTGCAGTGATTTTATAAAAAATCACGAATT
AGACGCTTATCAAGCGAAAATTCATCAAATTCACGAACAGATTCATGAAAAAACGGGCCTGGGTAATGATGCCCTTGATT
GGCTTGAATTACCTCTAAATTATGAACAGTCTATTCCAGTGACAAAAATTAAGGAACTGGCAGAAAATATCAGGTCTAAA
GCTGACGTGTTTTTAGTAATCGGCGTTGGAGGTTCTTATATTGGAGCCAGGGCAGCCATTGAATTTTTACGACCTGATAA
TAATTCTCCTGAGATTTTATACTTGGGTCATCATCTTTCACCACGCTATATCAATGAAGTGCTAGCTTCTCTGGAGGGAC
GTCAGGTATTTGTCAATGTTATATCCAAATCCGGGGGAACTTTGGAGCCTTCTCTTGCCTTTCGCACTATTCGATCTTTT
ATGGAAGAGAGATTTGGTAAAGATGAAGCCAGGCGGAGGATTATTGCAACTACCGATGGTGAGAAAGGAAAGCTTAAAGC
CTTGGCTGACAAAGAGGGCTATGAAACACTTGTTATACCTGATGGCATCGGTGGACGGTATTCAGTATTGACACCAGTCG
GGCTTCTTCCCATTGCTGTTTCCGGAGTGAATATTAAAGACATGTTAAATGGTGCACAGAAAGCTTATGAGATAACAAGT
ATACCCGATTTAGATAAAAACCCTGCCTATATTTATGCCGCATTAAGGCATATTCTACTCCAAAAAGGTAAACAAACTGA
AATACTTGTAACCTACGATCCCTTTGCAGGTTATTTAGGTGAGTGGTGGAAACAATTGTTTGGCGAAAGTGAAGGTAAAG
ATGGTAAAGGTATATTCCCGACCAGGGCAGATTTTACTACAGATCTACATTCACTAGGTCAGTATATACAAGAGGGTAGT
AGGCACTTATTTGCCACAACCGTATGGTGGGAGACTGAGGATGACTTAGTACTTCCAGGTTTAAATTATAGCCGAGGAGA
AGAAGGTGACAACAAATCTAACCATGAAAATGATGACGGTTTAACTTATTTACAAGGAAAAAGTTTTCATGAAATAAACC
GTCAGGCATTTTTGGGTACTGTTCAGGCGCATAACTGGGGAGGTGTTCCTAATATTGTAATTTCACTCCCAGAAATCAAT
TCTTATTATTTGGGACTCTTATTTTATTTCTTCATGAAATCCTGTGCGGCCAGTGGTTATTTATTAGGAGTTAATCCCTT
TAATCAACCAGGTGTAGAAGCTTATAAACAAAATGTTTTGTCTAGACTAGAACAAATTTGA

Upstream 100 bases:

>100_bases
AAGAACCTGATTACGATATTTATGAGCTTTCTCAAAGCCTGTCAATCTAAATATAATTGATCATTCAAATTGTACAAAAC
CTATATTAGAGGTGATCTCT

Downstream 100 bases:

>100_bases
TACTAGGTGACTTAAATTACATGATTTTCACACCTGTATTCACACGTATAAATAAATCTTTCTGATGTGAATATGGGTGT
GATTTTTGGTGTAAATTTGC

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI A; Phosphoglucose isomerase A; PGI-A; Phosphohexose isomerase A; PHI-A [H]

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MKEYQLAVERIEVNWNYCSDFIKNHELDAYQAKIHQIHEQIHEKTGLGNDALDWLELPLNYEQSIPVTKIKELAENIRSK
ADVFLVIGVGGSYIGARAAIEFLRPDNNSPEILYLGHHLSPRYINEVLASLEGRQVFVNVISKSGGTLEPSLAFRTIRSF
MEERFGKDEARRRIIATTDGEKGKLKALADKEGYETLVIPDGIGGRYSVLTPVGLLPIAVSGVNIKDMLNGAQKAYEITS
IPDLDKNPAYIYAALRHILLQKGKQTEILVTYDPFAGYLGEWWKQLFGESEGKDGKGIFPTRADFTTDLHSLGQYIQEGS
RHLFATTVWWETEDDLVLPGLNYSRGEEGDNKSNHENDDGLTYLQGKSFHEINRQAFLGTVQAHNWGGVPNIVISLPEIN
SYYLGLLFYFFMKSCAASGYLLGVNPFNQPGVEAYKQNVLSRLEQI

Sequences:

>Translated_446_residues
MKEYQLAVERIEVNWNYCSDFIKNHELDAYQAKIHQIHEQIHEKTGLGNDALDWLELPLNYEQSIPVTKIKELAENIRSK
ADVFLVIGVGGSYIGARAAIEFLRPDNNSPEILYLGHHLSPRYINEVLASLEGRQVFVNVISKSGGTLEPSLAFRTIRSF
MEERFGKDEARRRIIATTDGEKGKLKALADKEGYETLVIPDGIGGRYSVLTPVGLLPIAVSGVNIKDMLNGAQKAYEITS
IPDLDKNPAYIYAALRHILLQKGKQTEILVTYDPFAGYLGEWWKQLFGESEGKDGKGIFPTRADFTTDLHSLGQYIQEGS
RHLFATTVWWETEDDLVLPGLNYSRGEEGDNKSNHENDDGLTYLQGKSFHEINRQAFLGTVQAHNWGGVPNIVISLPEIN
SYYLGLLFYFFMKSCAASGYLLGVNPFNQPGVEAYKQNVLSRLEQI
>Mature_446_residues
MKEYQLAVERIEVNWNYCSDFIKNHELDAYQAKIHQIHEQIHEKTGLGNDALDWLELPLNYEQSIPVTKIKELAENIRSK
ADVFLVIGVGGSYIGARAAIEFLRPDNNSPEILYLGHHLSPRYINEVLASLEGRQVFVNVISKSGGTLEPSLAFRTIRSF
MEERFGKDEARRRIIATTDGEKGKLKALADKEGYETLVIPDGIGGRYSVLTPVGLLPIAVSGVNIKDMLNGAQKAYEITS
IPDLDKNPAYIYAALRHILLQKGKQTEILVTYDPFAGYLGEWWKQLFGESEGKDGKGIFPTRADFTTDLHSLGQYIQEGS
RHLFATTVWWETEDDLVLPGLNYSRGEEGDNKSNHENDDGLTYLQGKSFHEINRQAFLGTVQAHNWGGVPNIVISLPEIN
SYYLGLLFYFFMKSCAASGYLLGVNPFNQPGVEAYKQNVLSRLEQI

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 50126; Mature: 50126

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEYQLAVERIEVNWNYCSDFIKNHELDAYQAKIHQIHEQIHEKTGLGNDALDWLELPLN
CCCHHEEEEHEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCC
YEQSIPVTKIKELAENIRSKADVFLVIGVGGSYIGARAAIEFLRPDNNSPEILYLGHHLS
CCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEEECCCC
PRYINEVLASLEGRQVFVNVISKSGGTLEPSLAFRTIRSFMEERFGKDEARRRIIATTDG
HHHHHHHHHHCCCCCEEEEHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCEEEEECCC
EKGKLKALADKEGYETLVIPDGIGGRYSVLTPVGLLPIAVSGVNIKDMLNGAQKAYEITS
CCCCEEEEECCCCCEEEEEECCCCCCEEHHCCCCHHHHEECCCCHHHHHHHHHHHEEECC
IPDLDKNPAYIYAALRHILLQKGKQTEILVTYDPFAGYLGEWWKQLFGESEGKDGKGIFP
CCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCC
TRADFTTDLHSLGQYIQEGSRHLFATTVWWETEDDLVLPGLNYSRGEEGDNKSNHENDDG
CCCCHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCEEECCCCCCCCCCCCCCCCCCCCCC
LTYLQGKSFHEINRQAFLGTVQAHNWGGVPNIVISLPEINSYYLGLLFYFFMKSCAASGY
EEEECCCCHHHHHHHHHEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCE
LLGVNPFNQPGVEAYKQNVLSRLEQI
EEECCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKEYQLAVERIEVNWNYCSDFIKNHELDAYQAKIHQIHEQIHEKTGLGNDALDWLELPLN
CCCHHEEEEHEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCC
YEQSIPVTKIKELAENIRSKADVFLVIGVGGSYIGARAAIEFLRPDNNSPEILYLGHHLS
CCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEEECCCC
PRYINEVLASLEGRQVFVNVISKSGGTLEPSLAFRTIRSFMEERFGKDEARRRIIATTDG
HHHHHHHHHHCCCCCEEEEHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCEEEEECCC
EKGKLKALADKEGYETLVIPDGIGGRYSVLTPVGLLPIAVSGVNIKDMLNGAQKAYEITS
CCCCEEEEECCCCCEEEEEECCCCCCEEHHCCCCHHHHEECCCCHHHHHHHHHHHEEECC
IPDLDKNPAYIYAALRHILLQKGKQTEILVTYDPFAGYLGEWWKQLFGESEGKDGKGIFP
CCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCC
TRADFTTDLHSLGQYIQEGSRHLFATTVWWETEDDLVLPGLNYSRGEEGDNKSNHENDDG
CCCCHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCEEECCCCCCCCCCCCCCCCCCCCCC
LTYLQGKSFHEINRQAFLGTVQAHNWGGVPNIVISLPEINSYYLGLLFYFFMKSCAASGY
EEEECCCCHHHHHHHHHEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCE
LLGVNPFNQPGVEAYKQNVLSRLEQI
EEECCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2532320 [H]