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The map label for this gene is ygbD [C]

Identifier: 188585540

GI number: 188585540

Start: 967433

End: 968800

Strand: Direct

Name: ygbD [C]

Synonym: Nther_0912

Alternate gene names: 188585540

Gene position: 967433-968800 (Clockwise)

Preceding gene: 188585538

Following gene: 188585541

Centisome position: 30.56

GC content: 35.89

Gene sequence:

>1368_bases
TTGAACCCTGAAGAACAACAAAAATTCAGAGTAATCATTGTAGGGTCTGGTGTAGCAGCGCGAAGTGCTATTCAAAGTTT
AAATTTATACAAAAATTTAGATATCACTGTTATTAGAAGAGATGATCATCAAATTGTTCCTTGTGCAATACCTTACACTT
TTAAAAGACTACAGCCGAGTGACATAATAGGTGACGATAAAAACTGGGACACCTTAGACGCCCGAATCATTAATGATGAA
GTTGTGAATATAGACAGGGAAAATAAAATGTTAAGGCTGAAAAGTGGTAGTTCGTATTCATATGATAGGTTAATTTTGGC
TACAGGAGCTAATCCAATTAAACCTCCTATTAAAGGTATGAATAAAGAAAATGTTTTTTTCGTTGAAAAAAATGCCAGAC
AAATTAGTGAGTTACAGGAAAAAGCTGCTAGTTCTGGAAGGGTTGTAATTATTGGTGGGGGCTTTATTGGAGTTGAGATA
GCTGATGAACTGAGCGGAAGTGGTAAGGATATTCATTTGATAGAGACAGAACACAGACTACTTCCTAAGGCCTTTGATTC
TAAAATTTCTGATCGAGTGGAGAAGATATTGGGTGAACAGGGAGTTACTGTACACACAAATAAATTTGTCACAGAAATAA
AATCCAATAAAATTGTAATGTCAGGCCAAGATAAATCAGGTGAATATGAACTGGCTACAGATATGGTAATATGTGCAATA
GGTGTTACGCCAAATTCCGAATTGGCTGAAGCTTCAGGCATAGCTGTTAATAGTGCTGATAAAGGAATTATTGTTGATGA
CTATTATTATAGTTCAGATCCTAATATCTTAGCTTGCGGCGATTGTATTTCAAAACGAGATTTTAATAGTGGTGGTGAGT
CAGGAGTTAGATTGGCATCAACAGCTGCTTCTGAAGGAAAAGTAGCAGGTTTCAATATTTTTAATAGACGTTTTCCTAAC
AACAAAGGAGTCATCAACCTCTTTAATACCAAAATAGGAGATACAAGTTTTGCAGCAGCAGGGATAACTGAGTTTGAAGC
TAAAAAGAAGGGGTGTCCAGTAGTAAGTATAGATGGCAATTTTCCCGATAGACATCCAACTAAATTTTCTGATGTTACAA
CCAACTATGTCAAATTGATTTTTAACAGTTTTAACGGGAAACTTTTAGGGGGGCAAGTACAAGGAAGCAAAAGTATTGGA
GAATTTATTAACACTGTTGGTTTAGCGATTCAACATGAGTTAACTGCCTATGATTTGGCATCAGTTCAGTATGCTACTCA
CCCCCTGCTAACTACAGGTCCAAGTGGATATCCACTTTTAAAACTATCTATAGAGGCTATTAGAAATCTGACAGGAAATG
AAAATTAA

Upstream 100 bases:

>100_bases
GGTAGTTTTGACAATTAATTATGTCTATGTTATATTTTAGATACCGCATACCCCCGAGGGGTATACAAAATATAAAATTT
TATAATTAGGGGGAATTATT

Downstream 100 bases:

>100_bases
AAGTATGAAATAATCATTGAGCTTTACAAGGGAGGTATTGTTGGTAAAAACTCACTGATAGAGGGAGGAAATTATTATGT
CAACTGCATCTTATTTTATT

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: NOXase [H]

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MNPEEQQKFRVIIVGSGVAARSAIQSLNLYKNLDITVIRRDDHQIVPCAIPYTFKRLQPSDIIGDDKNWDTLDARIINDE
VVNIDRENKMLRLKSGSSYSYDRLILATGANPIKPPIKGMNKENVFFVEKNARQISELQEKAASSGRVVIIGGGFIGVEI
ADELSGSGKDIHLIETEHRLLPKAFDSKISDRVEKILGEQGVTVHTNKFVTEIKSNKIVMSGQDKSGEYELATDMVICAI
GVTPNSELAEASGIAVNSADKGIIVDDYYYSSDPNILACGDCISKRDFNSGGESGVRLASTAASEGKVAGFNIFNRRFPN
NKGVINLFNTKIGDTSFAAAGITEFEAKKKGCPVVSIDGNFPDRHPTKFSDVTTNYVKLIFNSFNGKLLGGQVQGSKSIG
EFINTVGLAIQHELTAYDLASVQYATHPLLTTGPSGYPLLKLSIEAIRNLTGNEN

Sequences:

>Translated_455_residues
MNPEEQQKFRVIIVGSGVAARSAIQSLNLYKNLDITVIRRDDHQIVPCAIPYTFKRLQPSDIIGDDKNWDTLDARIINDE
VVNIDRENKMLRLKSGSSYSYDRLILATGANPIKPPIKGMNKENVFFVEKNARQISELQEKAASSGRVVIIGGGFIGVEI
ADELSGSGKDIHLIETEHRLLPKAFDSKISDRVEKILGEQGVTVHTNKFVTEIKSNKIVMSGQDKSGEYELATDMVICAI
GVTPNSELAEASGIAVNSADKGIIVDDYYYSSDPNILACGDCISKRDFNSGGESGVRLASTAASEGKVAGFNIFNRRFPN
NKGVINLFNTKIGDTSFAAAGITEFEAKKKGCPVVSIDGNFPDRHPTKFSDVTTNYVKLIFNSFNGKLLGGQVQGSKSIG
EFINTVGLAIQHELTAYDLASVQYATHPLLTTGPSGYPLLKLSIEAIRNLTGNEN
>Mature_455_residues
MNPEEQQKFRVIIVGSGVAARSAIQSLNLYKNLDITVIRRDDHQIVPCAIPYTFKRLQPSDIIGDDKNWDTLDARIINDE
VVNIDRENKMLRLKSGSSYSYDRLILATGANPIKPPIKGMNKENVFFVEKNARQISELQEKAASSGRVVIIGGGFIGVEI
ADELSGSGKDIHLIETEHRLLPKAFDSKISDRVEKILGEQGVTVHTNKFVTEIKSNKIVMSGQDKSGEYELATDMVICAI
GVTPNSELAEASGIAVNSADKGIIVDDYYYSSDPNILACGDCISKRDFNSGGESGVRLASTAASEGKVAGFNIFNRRFPN
NKGVINLFNTKIGDTSFAAAGITEFEAKKKGCPVVSIDGNFPDRHPTKFSDVTTNYVKLIFNSFNGKLLGGQVQGSKSIG
EFINTVGLAIQHELTAYDLASVQYATHPLLTTGPSGYPLLKLSIEAIRNLTGNEN

Specific function: Catalyzes the four-electron reduction of molecular oxygen to water [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=313, Percent_Identity=23.6421725239617, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI226437568, Length=313, Percent_Identity=23.6421725239617, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI65787454, Length=313, Percent_Identity=23.6421725239617, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4757732, Length=291, Percent_Identity=24.3986254295533, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI22202629, Length=291, Percent_Identity=24.3986254295533, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI50301238, Length=348, Percent_Identity=25.5747126436782, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1789065, Length=295, Percent_Identity=26.7796610169492, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1786307, Length=333, Percent_Identity=26.4264264264264, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1789765, Length=296, Percent_Identity=28.0405405405405, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789915, Length=263, Percent_Identity=26.2357414448669, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788892, Length=207, Percent_Identity=27.536231884058, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787352, Length=243, Percent_Identity=27.5720164609054, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081717, Length=376, Percent_Identity=26.063829787234, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17559934, Length=338, Percent_Identity=27.5147928994083, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71983419, Length=263, Percent_Identity=27.7566539923954, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71983429, Length=263, Percent_Identity=27.7566539923954, Blast_Score=72, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6325166, Length=343, Percent_Identity=25.9475218658892, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639257, Length=329, Percent_Identity=24.6200607902736, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI281359715, Length=295, Percent_Identity=25.0847457627119, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI281359713, Length=295, Percent_Identity=25.0847457627119, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24639250, Length=295, Percent_Identity=25.0847457627119, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI18543267, Length=295, Percent_Identity=25.0847457627119, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24639252, Length=295, Percent_Identity=25.0847457627119, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21358499, Length=291, Percent_Identity=28.5223367697594, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24581020, Length=194, Percent_Identity=25.2577319587629, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28573993, Length=194, Percent_Identity=25.2577319587629, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24585130, Length=288, Percent_Identity=23.6111111111111, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 49500; Mature: 49500

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPEEQQKFRVIIVGSGVAARSAIQSLNLYKNLDITVIRRDDHQIVPCAIPYTFKRLQPS
CCCCCCCEEEEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCHHHHCCCCC
DIIGDDKNWDTLDARIINDEVVNIDRENKMLRLKSGSSYSYDRLILATGANPIKPPIKGM
CCCCCCCCCCCEEEEEECCEEEEECCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCC
NKENVFFVEKNARQISELQEKAASSGRVVIIGGGFIGVEIADELSGSGKDIHLIETEHRL
CCCCEEEEECCHHHHHHHHHHHHCCCCEEEEECCEEEEEEHHHCCCCCCEEEEEECCHHH
LPKAFDSKISDRVEKILGEQGVTVHTNKFVTEIKSNKIVMSGQDKSGEYELATDMVICAI
CHHHHHHHHHHHHHHHHCCCCCEEECCHHHEECCCCEEEEECCCCCCCEEEECCEEEEEE
GVTPNSELAEASGIAVNSADKGIIVDDYYYSSDPNILACGDCISKRDFNSGGESGVRLAS
ECCCCCHHHHCCCEEEECCCCCEEEECEEECCCCCEEEECCCCCCCCCCCCCCCCEEEEE
TAASEGKVAGFNIFNRRFPNNKGVINLFNTKIGDTSFAAAGITEFEAKKKGCPVVSIDGN
CCCCCCCEEEEEHHHHCCCCCCCEEEEECCCCCCCCCHHCCCHHHHHHHCCCCEEEECCC
FPDRHPTKFSDVTTNYVKLIFNSFNGKLLGGQVQGSKSIGEFINTVGLAIQHELTAYDLA
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEECEECCCHHHHHHHHHHHHHEEECCCHHHHH
SVQYATHPLLTTGPSGYPLLKLSIEAIRNLTGNEN
HEEHHCCCEEECCCCCCEEEEEEHHHHHCCCCCCC
>Mature Secondary Structure
MNPEEQQKFRVIIVGSGVAARSAIQSLNLYKNLDITVIRRDDHQIVPCAIPYTFKRLQPS
CCCCCCCEEEEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCHHHHCCCCC
DIIGDDKNWDTLDARIINDEVVNIDRENKMLRLKSGSSYSYDRLILATGANPIKPPIKGM
CCCCCCCCCCCEEEEEECCEEEEECCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCC
NKENVFFVEKNARQISELQEKAASSGRVVIIGGGFIGVEIADELSGSGKDIHLIETEHRL
CCCCEEEEECCHHHHHHHHHHHHCCCCEEEEECCEEEEEEHHHCCCCCCEEEEEECCHHH
LPKAFDSKISDRVEKILGEQGVTVHTNKFVTEIKSNKIVMSGQDKSGEYELATDMVICAI
CHHHHHHHHHHHHHHHHCCCCCEEECCHHHEECCCCEEEEECCCCCCCEEEECCEEEEEE
GVTPNSELAEASGIAVNSADKGIIVDDYYYSSDPNILACGDCISKRDFNSGGESGVRLAS
ECCCCCHHHHCCCEEEECCCCCEEEECEEECCCCCEEEECCCCCCCCCCCCCCCCEEEEE
TAASEGKVAGFNIFNRRFPNNKGVINLFNTKIGDTSFAAAGITEFEAKKKGCPVVSIDGN
CCCCCCCEEEEEHHHHCCCCCCCEEEEECCCCCCCCCHHCCCHHHHHHHCCCCEEEECCC
FPDRHPTKFSDVTTNYVKLIFNSFNGKLLGGQVQGSKSIGEFINTVGLAIQHELTAYDLA
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEECEECCCHHHHHHHHHHHHHEEECCCHHHHH
SVQYATHPLLTTGPSGYPLLKLSIEAIRNLTGNEN
HEEHHCCCEEECCCCCCEEEEEEHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]