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The map label for this gene is zupT [H]

Identifier: 188585202

GI number: 188585202

Start: 591825

End: 592544

Strand: Reverse

Name: zupT [H]

Synonym: Nther_0563

Alternate gene names: 188585202

Gene position: 592544-591825 (Counterclockwise)

Preceding gene: 188585206

Following gene: 188585201

Centisome position: 18.72

GC content: 38.47

Gene sequence:

>720_bases
ATGGAAATTATGATTTTTAGTACACTGGCTGGTATGTCAACTTTAATGGGAGCTGGGATAGTTTTTTTGTTCGGTACACC
TTCTCGGATTATATTAGCAGTTATCTTGGGGTTCTCAGGTGGTGTAATGTTTTCTGTCAGTATTTTTGAGTTAATTACTG
AAGCTCTAAAGTTGAGCTATCAAGGACCAGTCCTGGCTGCATTTTTTGCAGGGGGCTTTATCATGTGGTGTTTTTCTGTA
GTAATAAATAAGTTTCTCACCCCTACTCACCAGATGTATGAGACTGAAGATTTTCTAAAGACTGGCTATTTAGTAATTTT
GGGAATTGCTCTGCATAATCTACCAGAAGGATTAGCTATCGGTACAGGAATAGAAGCTTCCCCCGACTTAAGCCTGATAA
TAGCTATCACCTTGGCAATTCATAATATACCTGAAGGAATGGCAACAGCTGGACCATTAAAAGCTGGTGGTTTAAACACT
TTCTCTATAATTATTTTAATCACCTTTGCAGGATTGGTAACCCCTCTTGGTACCATGGCCGGGATTATTTTTATGGGAGT
TCTTCCCGATCTAGTGGGAATAAGTTTGGGAATTGCCGGGGGAGCTATGATTTATTTGGTTATCGATGAATTACTCCCCA
AAGCTCAAAGTTCTAATAAAGTTTTAGCAAATTCAGGGTTTTTTTTGGGATTTATCTTGGGAAAACTTATAGTAGGCTAA

Upstream 100 bases:

>100_bases
AAATCATTTCGAAAACCTACTTTTCGGGGGAATTATTTAGTAAGCCAGCTAATATGTTTAAATAAAAAGCTTTATTAAAG
TCTTCTATAGGCGGGATAAT

Downstream 100 bases:

>100_bases
ATCGATTAAATATTTAAATACAGCTGATAAATTTCACATAAATACCATGTTTATGGGAAGAATTAGTATTTGAAAGTTTA
TTTACAATCTTTACAAAGGG

Product: zinc/iron permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MEIMIFSTLAGMSTLMGAGIVFLFGTPSRIILAVILGFSGGVMFSVSIFELITEALKLSYQGPVLAAFFAGGFIMWCFSV
VINKFLTPTHQMYETEDFLKTGYLVILGIALHNLPEGLAIGTGIEASPDLSLIIAITLAIHNIPEGMATAGPLKAGGLNT
FSIIILITFAGLVTPLGTMAGIIFMGVLPDLVGISLGIAGGAMIYLVIDELLPKAQSSNKVLANSGFFLGFILGKLIVG

Sequences:

>Translated_239_residues
MEIMIFSTLAGMSTLMGAGIVFLFGTPSRIILAVILGFSGGVMFSVSIFELITEALKLSYQGPVLAAFFAGGFIMWCFSV
VINKFLTPTHQMYETEDFLKTGYLVILGIALHNLPEGLAIGTGIEASPDLSLIIAITLAIHNIPEGMATAGPLKAGGLNT
FSIIILITFAGLVTPLGTMAGIIFMGVLPDLVGISLGIAGGAMIYLVIDELLPKAQSSNKVLANSGFFLGFILGKLIVG
>Mature_239_residues
MEIMIFSTLAGMSTLMGAGIVFLFGTPSRIILAVILGFSGGVMFSVSIFELITEALKLSYQGPVLAAFFAGGFIMWCFSV
VINKFLTPTHQMYETEDFLKTGYLVILGIALHNLPEGLAIGTGIEASPDLSLIIAITLAIHNIPEGMATAGPLKAGGLNT
FSIIILITFAGLVTPLGTMAGIIFMGVLPDLVGISLGIAGGAMIYLVIDELLPKAQSSNKVLANSGFFLGFILGKLIVG

Specific function: Mediates zinc uptake. May also transport other divalent cations [H]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily [H]

Homologues:

Organism=Homo sapiens, GI229577422, Length=138, Percent_Identity=35.5072463768116, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI229577418, Length=138, Percent_Identity=35.5072463768116, Blast_Score=81, Evalue=7e-16,
Organism=Escherichia coli, GI1789419, Length=228, Percent_Identity=31.5789473684211, Blast_Score=93, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17507805, Length=295, Percent_Identity=27.1186440677966, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24652846, Length=160, Percent_Identity=32.5, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 25007; Mature: 25007

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIMIFSTLAGMSTLMGAGIVFLFGTPSRIILAVILGFSGGVMFSVSIFELITEALKLSY
CEEEEEHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
QGPVLAAFFAGGFIMWCFSVVINKFLTPTHQMYETEDFLKTGYLVILGIALHNLPEGLAI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
GTGIEASPDLSLIIAITLAIHNIPEGMATAGPLKAGGLNTFSIIILITFAGLVTPLGTMA
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GIIFMGVLPDLVGISLGIAGGAMIYLVIDELLPKAQSSNKVLANSGFFLGFILGKLIVG
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure
MEIMIFSTLAGMSTLMGAGIVFLFGTPSRIILAVILGFSGGVMFSVSIFELITEALKLSY
CEEEEEHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
QGPVLAAFFAGGFIMWCFSVVINKFLTPTHQMYETEDFLKTGYLVILGIALHNLPEGLAI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
GTGIEASPDLSLIIAITLAIHNIPEGMATAGPLKAGGLNTFSIIILITFAGLVTPLGTMA
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GIIFMGVLPDLVGISLGIAGGAMIYLVIDELLPKAQSSNKVLANSGFFLGFILGKLIVG
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA