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The map label for this gene is 188528280

Identifier: 188528280

GI number: 188528280

Start: 1503055

End: 1503408

Strand: Direct

Name: 188528280

Synonym: HPSH_07750

Alternate gene names: NA

Gene position: 1503055-1503408 (Clockwise)

Preceding gene: 188528279

Following gene: 188528281

Centisome position: 93.44

GC content: 34.75

Gene sequence:

>354_bases
ATGAAAACCCAACAAGGCATTCATATCCATAACTTGGTGTTTGAAACGATTTTGGGGATTTTAGAATTTGAACGCTTAAA
ACCCCAAAAAATAAGCGTGAATTTGGATCTTTTCTACACGCAATTACCCAATAAGGCTTATTTAGATTACATAAAAATCC
AAGAGCTTATTCAAAAAATGATGCAAGAAAACCAATACTTACTCATTGAAGACGCCCTGAAAGATTTGAGCCATGCTTTA
AAAACGCGCTATAGTGAAATCTCTGAGCTTCATTTAAAAATCAGCAAGTTAGAAATTTCTCCAAATTCTCAAGTGGGAGC
GAGCGTGAAAATTCGCTATGAAAACGATCTTTAG

Upstream 100 bases:

>100_bases
TCGGCACGCAAACGCCTATGGTGCTTATTTTTATTTTTACCCTTATCAAGCATGCGGGCAATATTTTTAATTTATTAGCC
GGCAAGGAAAAGAAAATCTT

Downstream 100 bases:

>100_bases
CTTCTTTTTCCTTCTTATTGTTTTAAAAGCAAACCCCATAAACCCTTTATTAGAGCCGTTATATTTCCCAAATTACGCGC
AATTTTTAAATTTAGAACCT

Product: dihydroneopterin aldolase

Products: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine; glycolaldehyde

Alternate protein names: NA

Number of amino acids: Translated: 117; Mature: 117

Protein sequence:

>117_residues
MKTQQGIHIHNLVFETILGILEFERLKPQKISVNLDLFYTQLPNKAYLDYIKIQELIQKMMQENQYLLIEDALKDLSHAL
KTRYSEISELHLKISKLEISPNSQVGASVKIRYENDL

Sequences:

>Translated_117_residues
MKTQQGIHIHNLVFETILGILEFERLKPQKISVNLDLFYTQLPNKAYLDYIKIQELIQKMMQENQYLLIEDALKDLSHAL
KTRYSEISELHLKISKLEISPNSQVGASVKIRYENDL
>Mature_117_residues
MKTQQGIHIHNLVFETILGILEFERLKPQKISVNLDLFYTQLPNKAYLDYIKIQELIQKMMQENQYLLIEDALKDLSHAL
KTRYSEISELHLKISKLEISPNSQVGASVKIRYENDL

Specific function: Unknown

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.1.2.25

Molecular weight: Translated: 13716; Mature: 13716

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTQQGIHIHNLVFETILGILEFERLKPQKISVNLDLFYTQLPNKAYLDYIKIQELIQKM
CCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHH
MQENQYLLIEDALKDLSHALKTRYSEISELHLKISKLEISPNSQVGASVKIRYENDL
HHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MKTQQGIHIHNLVFETILGILEFERLKPQKISVNLDLFYTQLPNKAYLDYIKIQELIQKM
CCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHH
MQENQYLLIEDALKDLSHALKTRYSEISELHLKISKLEISPNSQVGASVKIRYENDL
HHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-; $dihydropteridine

Specific reaction: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8- $dihydropteridine = 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA