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The map label for this gene is aroA [H]

Identifier: 188527834

GI number: 188527834

Start: 1065395

End: 1066684

Strand: Direct

Name: aroA [H]

Synonym: HPSH_05400

Alternate gene names: 188527834

Gene position: 1065395-1066684 (Clockwise)

Preceding gene: 188527833

Following gene: 188527835

Centisome position: 66.23

GC content: 39.22

Gene sequence:

>1290_bases
GTGATAGAGCTTGACATTAACGCTAGCGATAAATCGCTCTCACACAGAGCCGTTATTTTTAGCCTGCTCGCTCAAAAGCC
TTGTGTCGTGCGGAATTTTTTAATGGGAGAGGATTGTTTGAGCTCTTTAGAAATCGCTCAAAATTTAGGGGCTAAAGTGG
AAAATATTGCCAAAAATTCTTTTAAAATCACGCCCCCAACGGCTTTAAAAGAGCCTAACAAGATCTTAAATTGCAACAAT
TCTGGCACCAGTATGCGTTTATACAGCGGGCTTTTAAGCGCTCAAAAAGGCCTTTTTGTTTTAAGCGGGGACAATTCTTT
AAACGCGCGCCCCATGAAAAGAATCATTGAGCCTTTGAAAGCTTTTGGGGCAAAGATTTTAGGGAGAGAGGATAACCATT
TCGCCCCCTTAGCGATCTTAGGGAGTCCTTTAAAAGCTTGCGATTATGAAAGCCCTATCGCTTCAGCTCAAGTCAAAAGC
GCTTTTATTTTAAGCGCCCTACAAGCTCAAGGCTCAAGCACCTATAAAGAAAATGAGCTTAGCCGTAACCACACAGAAAT
CATGCTTAAAAGTTTGGGAGCTAATATTCAAAATCAAAACGGCGTTTTAACGATTTTACCCCTAGAAAAACCCCTAGAAG
CCTTTGATTTTACTATAGCTAATGATCCTTCTAGTGCGTTTTTTTTCGCCCTTTCTTGTGCGATTACGCCCAAAAGCCGC
CTTCTTTTAAAAAATGTCTTGCTCAACCCCACCCGCATAGAAGCTTTTGAAGCGTTGAAAAAAATGGGCGCTTCCATAGA
GTATGCGATTCAATCCAAAGATTTAGAAATGATTGGCGATATTTATATAGAGCATGCCCCTTTAAAAGCGATCAGTATTG
AGCAAAATATCGCTAGCCTTATTGATGAAATCCCTGCTTTAAGTATCGCTATGCTTTTTGCAAAAGGCAAAAGCATGGTC
AAAAACGCTAAAGATTTACGATCTAAAGAAAGCGATAGGATTAAAGCGGTTGTTTCTAATTTCAAAGCTTTAGGGATTGA
GTGCGAAGAGTTTGAAGACGGGTTTTGCATAGAGGGATTAGAAGATATAAGCCAATTAAAACAGCGCTTTTCTCAAAAAA
AACCCCCCCTTATCCAAAGCTTTAACGATCACAGGATTGCGATGAGTTTCGCTATTTTAACTTTAGCATTGCCTTTAGAA
ATTGACAATTTAGAATGCGCAAACATTTCTTTCCCGCAATTCAAACGCTTACTCAATCTATTCAAAAAAAGGAGTTTTAA
TGGAAATTAA

Upstream 100 bases:

>100_bases
CCTAAATGACGAAGAGGTCAATTCAGCCGTGCAAAAAGCGCTTGAAATTTTAGAAAAAGAATTTAACGCCCGCCTTAAGG
GATAATATAAAGGATAAAAT

Downstream 100 bases:

>100_bases
AATGGCTAAGGATTATGGTTTTTGTTTTGGCGTCAAAAGAGCGATACAAATCGCTGAAAAAAATCAAAACAGCTTGATTT
TTGGCTCGCTCATTCATAAC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MIELDINASDKSLSHRAVIFSLLAQKPCVVRNFLMGEDCLSSLEIAQNLGAKVENIAKNSFKITPPTALKEPNKILNCNN
SGTSMRLYSGLLSAQKGLFVLSGDNSLNARPMKRIIEPLKAFGAKILGREDNHFAPLAILGSPLKACDYESPIASAQVKS
AFILSALQAQGSSTYKENELSRNHTEIMLKSLGANIQNQNGVLTILPLEKPLEAFDFTIANDPSSAFFFALSCAITPKSR
LLLKNVLLNPTRIEAFEALKKMGASIEYAIQSKDLEMIGDIYIEHAPLKAISIEQNIASLIDEIPALSIAMLFAKGKSMV
KNAKDLRSKESDRIKAVVSNFKALGIECEEFEDGFCIEGLEDISQLKQRFSQKKPPLIQSFNDHRIAMSFAILTLALPLE
IDNLECANISFPQFKRLLNLFKKRSFNGN

Sequences:

>Translated_429_residues
MIELDINASDKSLSHRAVIFSLLAQKPCVVRNFLMGEDCLSSLEIAQNLGAKVENIAKNSFKITPPTALKEPNKILNCNN
SGTSMRLYSGLLSAQKGLFVLSGDNSLNARPMKRIIEPLKAFGAKILGREDNHFAPLAILGSPLKACDYESPIASAQVKS
AFILSALQAQGSSTYKENELSRNHTEIMLKSLGANIQNQNGVLTILPLEKPLEAFDFTIANDPSSAFFFALSCAITPKSR
LLLKNVLLNPTRIEAFEALKKMGASIEYAIQSKDLEMIGDIYIEHAPLKAISIEQNIASLIDEIPALSIAMLFAKGKSMV
KNAKDLRSKESDRIKAVVSNFKALGIECEEFEDGFCIEGLEDISQLKQRFSQKKPPLIQSFNDHRIAMSFAILTLALPLE
IDNLECANISFPQFKRLLNLFKKRSFNGN
>Mature_429_residues
MIELDINASDKSLSHRAVIFSLLAQKPCVVRNFLMGEDCLSSLEIAQNLGAKVENIAKNSFKITPPTALKEPNKILNCNN
SGTSMRLYSGLLSAQKGLFVLSGDNSLNARPMKRIIEPLKAFGAKILGREDNHFAPLAILGSPLKACDYESPIASAQVKS
AFILSALQAQGSSTYKENELSRNHTEIMLKSLGANIQNQNGVLTILPLEKPLEAFDFTIANDPSSAFFFALSCAITPKSR
LLLKNVLLNPTRIEAFEALKKMGASIEYAIQSKDLEMIGDIYIEHAPLKAISIEQNIASLIDEIPALSIAMLFAKGKSMV
KNAKDLRSKESDRIKAVVSNFKALGIECEEFEDGFCIEGLEDISQLKQRFSQKKPPLIQSFNDHRIAMSFAILTLALPLE
IDNLECANISFPQFKRLLNLFKKRSFNGN

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=425, Percent_Identity=27.2941176470588, Blast_Score=113, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6320332, Length=447, Percent_Identity=23.2662192393736, Blast_Score=87, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 47270; Mature: 47270

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELDINASDKSLSHRAVIFSLLAQKPCVVRNFLMGEDCLSSLEIAQNLGAKVENIAKNS
CEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCC
FKITPPTALKEPNKILNCNNSGTSMRLYSGLLSAQKGLFVLSGDNSLNARPMKRIIEPLK
EEECCCHHHCCCCCEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHH
AFGAKILGREDNHFAPLAILGSPLKACDYESPIASAQVKSAFILSALQAQGSSTYKENEL
HHHHHHCCCCCCCCCCHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHH
SRNHTEIMLKSLGANIQNQNGVLTILPLEKPLEAFDFTIANDPSSAFFFALSCAITPKSR
CCHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHCEEEECCCCCCEEEEEEEECCCHHH
LLLKNVLLNPTRIEAFEALKKMGASIEYAIQSKDLEMIGDIYIEHAPLKAISIEQNIASL
HHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCEEEEHHHHHHHH
IDEIPALSIAMLFAKGKSMVKNAKDLRSKESDRIKAVVSNFKALGIECEEFEDGFCIEGL
HHHCCHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCH
EDISQLKQRFSQKKPPLIQSFNDHRIAMSFAILTLALPLEIDNLECANISFPQFKRLLNL
HHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHCEEECCCCCCCCCCHHHHHHHHH
FKKRSFNGN
HHHCCCCCC
>Mature Secondary Structure
MIELDINASDKSLSHRAVIFSLLAQKPCVVRNFLMGEDCLSSLEIAQNLGAKVENIAKNS
CEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCC
FKITPPTALKEPNKILNCNNSGTSMRLYSGLLSAQKGLFVLSGDNSLNARPMKRIIEPLK
EEECCCHHHCCCCCEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHH
AFGAKILGREDNHFAPLAILGSPLKACDYESPIASAQVKSAFILSALQAQGSSTYKENEL
HHHHHHCCCCCCCCCCHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHH
SRNHTEIMLKSLGANIQNQNGVLTILPLEKPLEAFDFTIANDPSSAFFFALSCAITPKSR
CCHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHCEEEECCCCCCEEEEEEEECCCHHH
LLLKNVLLNPTRIEAFEALKKMGASIEYAIQSKDLEMIGDIYIEHAPLKAISIEQNIASL
HHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCEEEEHHHHHHHH
IDEIPALSIAMLFAKGKSMVKNAKDLRSKESDRIKAVVSNFKALGIECEEFEDGFCIEGL
HHHCCHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCH
EDISQLKQRFSQKKPPLIQSFNDHRIAMSFAILTLALPLEIDNLECANISFPQFKRLLNL
HHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHCEEECCCCCCCCCCHHHHHHHHH
FKKRSFNGN
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA