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The map label for this gene is speA [H]

Identifier: 188527815

GI number: 188527815

Start: 1042645

End: 1044492

Strand: Reverse

Name: speA [H]

Synonym: HPSH_05300

Alternate gene names: 188527815

Gene position: 1044492-1042645 (Counterclockwise)

Preceding gene: 188527816

Following gene: 188527811

Centisome position: 64.93

GC content: 40.69

Gene sequence:

>1848_bases
ATGCAAGAAGTCCATGATTATGGGATTAATTTTTGGAGCAATAACGAATTTAAGATAGAAAAAGGCTTGGTTAAAGTTTG
CCATGGCAAAAACCCCTCGCTTTTAGAAATCGTTCAAAGCGTGCGCGATAAGGGCTATAGAGGGCCTTTGTTGGTGCGAT
TCCCCCATTTGGTGCAAAAACAAATCAAAAGCCTGTTTGATGCGTTTTCTTCAGCGATTAAAGAGTATCAATACAGCGGG
GCTTTTAAGGCGGTTTTCCCTTTAAAAGTCAATCAAATGCCCTCGTTTGTTTTACCTTTAGTGCAAGGGGCTAAGGGTTT
GAATTACGGCTTAGAGGCCGGTAGCAAGTCTGAACTCATCATCGCGATGAGTTACACTAACCCCACAGCCCCTATCACCG
TGAATGGCTTTAAAGACAAAGAAATGATTGAGCTTGGCTTTATCGCTAAGAGCATGCAGCATGAAATCACTTTAACGATT
GAGGGTTTGAACGAGTTAAAAACCATTATCGCCGTGGCTAAACAAAACGAGTTTTTAGCCTGCCCTAAAATTGGCATCCG
CATCCGTTTGCACAGCACTGGCACTGGCGTTTGGGCAAAGAGTGGGGGGATCAATTCTAAATTTGGTCTTAGCAGCACTG
AAGTTTTAGAAGCGATGCGCCTTTTAGAAGAAAACGACTTGTTAGAGCATTTCCACATGATACATTTCCACATAGGCTCT
CAAATCAGCGATATTTCGCCCTTAAAAAAGGCTTTAAGAGAAGCGGGTAACTTGTATGCAGAATTGCGTAAAATGGGCGC
TAAAAATCTTAATAGCGTGAATATTGGAGGGGGGTTAGCCGTAGAATACACCCAACACAAGCACCACCAAGACAAGAACT
ACACTTTAGAGGAATTCAGCGCTGATGTGGTGTTTTTATTGAGGGAAATTGTGAAAAACAAGCAGGAAATAGAGCCGGAT
ATTTTCATTGAATCAGGCCGTTATATTTCCGCTAACCATGCCGTTTTAGTGGCCCCGGTGTTAGAATTGTTTTCGCATGA
ATACAATGAAAAATCCCTAAAAATCAAAGAAAGTAATAACCCTCCCTTGATTGATGAAATGCTAGACTTGCTCGCTAATA
TCAATGAAAAAAACGCCATTGAATACTTGCATGATAGTTTTGATCACACCGAGTCGCTATTCACGCTTTTTGATTTGGGC
TATATTGATTTGATTGACAGGAGCAATACTGAAGTTTTAGCCCATTTGATCGTCAAAAAAGCGGTGCAATTGCTTTATGT
TAAGGATCATAACGATATTTTACGCATTCAAGAGCAGGTCCAAGAGCGCTATTTATTGAATTGCTCGTTTTTCCAAAGCT
TGCCGGATTATTGGGGCTTAAGACAGAATTTCCCGGTCATGCCCTTGAATAAATTAGATGAAAAGCCCACCAGGAGCGCG
AGCTTGTGGGATATTACTTGCGATAGCGATGGAGAAATCGCTTTTGATTCCACAAAGCCCTTGTTTTTGCACGATATAGA
TGTGGATGAAGAAGAATACTTTTTAGCGTTCTTTTTAGTGGGAGCGTATCAAGAAGTTTTAGGCATGAAACATAATTTAT
TCACGCACCCTACGGAATTTAGCGTGGTTTTTGATGAAAAAGGCGATTATGAAGTGGAAGATATTTGCGAAGCCCAAACG
ATTTTAGATGTGTTAGATGATTTAGACTATGACACTAAAGAGATCGAGCGCCTTTTAAAACAAAAAATTGAAGACAACAA
CCAACTGGACATGGAAGAAAAGAAAGAAATTATGGGGCGTTTGTATGTCATGCTGAGCGAAAACGGGTATTTGCGCACGA
TTTCTTAA

Upstream 100 bases:

>100_bases
ATTCAGTCATTCAAATTGAAAAAGTTTATGAAGAAGCGATCAAAGATTTTAAAAATAACCCCAGTCTTTTTAAAACCTTA
TCGTAACAAAAGGATAAAAA

Downstream 100 bases:

>100_bases
AGAGCGCTATAAATGGATTCAAACGGCTTTAATCGCTATCAATCCATAAAAGAAAAATAAGAGAGAATAAAAGAGAGAAA
AAGAGAGCCCCCTCCCCAAA

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 615; Mature: 615

Protein sequence:

>615_residues
MQEVHDYGINFWSNNEFKIEKGLVKVCHGKNPSLLEIVQSVRDKGYRGPLLVRFPHLVQKQIKSLFDAFSSAIKEYQYSG
AFKAVFPLKVNQMPSFVLPLVQGAKGLNYGLEAGSKSELIIAMSYTNPTAPITVNGFKDKEMIELGFIAKSMQHEITLTI
EGLNELKTIIAVAKQNEFLACPKIGIRIRLHSTGTGVWAKSGGINSKFGLSSTEVLEAMRLLEENDLLEHFHMIHFHIGS
QISDISPLKKALREAGNLYAELRKMGAKNLNSVNIGGGLAVEYTQHKHHQDKNYTLEEFSADVVFLLREIVKNKQEIEPD
IFIESGRYISANHAVLVAPVLELFSHEYNEKSLKIKESNNPPLIDEMLDLLANINEKNAIEYLHDSFDHTESLFTLFDLG
YIDLIDRSNTEVLAHLIVKKAVQLLYVKDHNDILRIQEQVQERYLLNCSFFQSLPDYWGLRQNFPVMPLNKLDEKPTRSA
SLWDITCDSDGEIAFDSTKPLFLHDIDVDEEEYFLAFFLVGAYQEVLGMKHNLFTHPTEFSVVFDEKGDYEVEDICEAQT
ILDVLDDLDYDTKEIERLLKQKIEDNNQLDMEEKKEIMGRLYVMLSENGYLRTIS

Sequences:

>Translated_615_residues
MQEVHDYGINFWSNNEFKIEKGLVKVCHGKNPSLLEIVQSVRDKGYRGPLLVRFPHLVQKQIKSLFDAFSSAIKEYQYSG
AFKAVFPLKVNQMPSFVLPLVQGAKGLNYGLEAGSKSELIIAMSYTNPTAPITVNGFKDKEMIELGFIAKSMQHEITLTI
EGLNELKTIIAVAKQNEFLACPKIGIRIRLHSTGTGVWAKSGGINSKFGLSSTEVLEAMRLLEENDLLEHFHMIHFHIGS
QISDISPLKKALREAGNLYAELRKMGAKNLNSVNIGGGLAVEYTQHKHHQDKNYTLEEFSADVVFLLREIVKNKQEIEPD
IFIESGRYISANHAVLVAPVLELFSHEYNEKSLKIKESNNPPLIDEMLDLLANINEKNAIEYLHDSFDHTESLFTLFDLG
YIDLIDRSNTEVLAHLIVKKAVQLLYVKDHNDILRIQEQVQERYLLNCSFFQSLPDYWGLRQNFPVMPLNKLDEKPTRSA
SLWDITCDSDGEIAFDSTKPLFLHDIDVDEEEYFLAFFLVGAYQEVLGMKHNLFTHPTEFSVVFDEKGDYEVEDICEAQT
ILDVLDDLDYDTKEIERLLKQKIEDNNQLDMEEKKEIMGRLYVMLSENGYLRTIS
>Mature_615_residues
MQEVHDYGINFWSNNEFKIEKGLVKVCHGKNPSLLEIVQSVRDKGYRGPLLVRFPHLVQKQIKSLFDAFSSAIKEYQYSG
AFKAVFPLKVNQMPSFVLPLVQGAKGLNYGLEAGSKSELIIAMSYTNPTAPITVNGFKDKEMIELGFIAKSMQHEITLTI
EGLNELKTIIAVAKQNEFLACPKIGIRIRLHSTGTGVWAKSGGINSKFGLSSTEVLEAMRLLEENDLLEHFHMIHFHIGS
QISDISPLKKALREAGNLYAELRKMGAKNLNSVNIGGGLAVEYTQHKHHQDKNYTLEEFSADVVFLLREIVKNKQEIEPD
IFIESGRYISANHAVLVAPVLELFSHEYNEKSLKIKESNNPPLIDEMLDLLANINEKNAIEYLHDSFDHTESLFTLFDLG
YIDLIDRSNTEVLAHLIVKKAVQLLYVKDHNDILRIQEQVQERYLLNCSFFQSLPDYWGLRQNFPVMPLNKLDEKPTRSA
SLWDITCDSDGEIAFDSTKPLFLHDIDVDEEEYFLAFFLVGAYQEVLGMKHNLFTHPTEFSVVFDEKGDYEVEDICEAQT
ILDVLDDLDYDTKEIERLLKQKIEDNNQLDMEEKKEIMGRLYVMLSENGYLRTIS

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=615, Percent_Identity=32.6829268292683, Blast_Score=331, Evalue=7e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 70214; Mature: 70214

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEVHDYGINFWSNNEFKIEKGLVKVCHGKNPSLLEIVQSVRDKGYRGPLLVRFPHLVQK
CCCCHHCCCEEECCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEECHHHHHH
QIKSLFDAFSSAIKEYQYSGAFKAVFPLKVNQMPSFVLPLVQGAKGLNYGLEAGSKSELI
HHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCEE
IAMSYTNPTAPITVNGFKDKEMIELGFIAKSMQHEITLTIEGLNELKTIIAVAKQNEFLA
EEEECCCCCCCEEECCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCEEE
CPKIGIRIRLHSTGTGVWAKSGGINSKFGLSSTEVLEAMRLLEENDLLEHFHMIHFHIGS
CCCCCEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
QISDISPLKKALREAGNLYAELRKMGAKNLNSVNIGGGLAVEYTQHKHHQDKNYTLEEFS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEEHHHHCCCCCCCCHHHHH
ADVVFLLREIVKNKQEIEPDIFIESGRYISANHAVLVAPVLELFSHEYNEKSLKIKESNN
HHHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCCHHHHHHHHHCCCCCCCEEEEECCCC
PPLIDEMLDLLANINEKNAIEYLHDSFDHTESLFTLFDLGYIDLIDRSNTEVLAHLIVKK
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCHHHHHHHHHHH
AVQLLYVKDHNDILRIQEQVQERYLLNCSFFQSLPDYWGLRQNFPVMPLNKLDEKPTRSA
HHHEEEEECCCHHHHHHHHHHHHHHCCHHHHHHCHHHCCCCCCCCCCCCHHCCCCCCCCC
SLWDITCDSDGEIAFDSTKPLFLHDIDVDEEEYFLAFFLVGAYQEVLGMKHNLFTHPTEF
EEEEEEECCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
SVVFDEKGDYEVEDICEAQTILDVLDDLDYDTKEIERLLKQKIEDNNQLDMEEKKEIMGR
EEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
LYVMLSENGYLRTIS
EEEEEECCCEEEECC
>Mature Secondary Structure
MQEVHDYGINFWSNNEFKIEKGLVKVCHGKNPSLLEIVQSVRDKGYRGPLLVRFPHLVQK
CCCCHHCCCEEECCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEECHHHHHH
QIKSLFDAFSSAIKEYQYSGAFKAVFPLKVNQMPSFVLPLVQGAKGLNYGLEAGSKSELI
HHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCEE
IAMSYTNPTAPITVNGFKDKEMIELGFIAKSMQHEITLTIEGLNELKTIIAVAKQNEFLA
EEEECCCCCCCEEECCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCEEE
CPKIGIRIRLHSTGTGVWAKSGGINSKFGLSSTEVLEAMRLLEENDLLEHFHMIHFHIGS
CCCCCEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
QISDISPLKKALREAGNLYAELRKMGAKNLNSVNIGGGLAVEYTQHKHHQDKNYTLEEFS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEEHHHHCCCCCCCCHHHHH
ADVVFLLREIVKNKQEIEPDIFIESGRYISANHAVLVAPVLELFSHEYNEKSLKIKESNN
HHHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCCHHHHHHHHHCCCCCCCEEEEECCCC
PPLIDEMLDLLANINEKNAIEYLHDSFDHTESLFTLFDLGYIDLIDRSNTEVLAHLIVKK
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCHHHHHHHHHHH
AVQLLYVKDHNDILRIQEQVQERYLLNCSFFQSLPDYWGLRQNFPVMPLNKLDEKPTRSA
HHHEEEEECCCHHHHHHHHHHHHHHCCHHHHHHCHHHCCCCCCCCCCCCHHCCCCCCCCC
SLWDITCDSDGEIAFDSTKPLFLHDIDVDEEEYFLAFFLVGAYQEVLGMKHNLFTHPTEF
EEEEEEECCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
SVVFDEKGDYEVEDICEAQTILDVLDDLDYDTKEIERLLKQKIEDNNQLDMEEKKEIMGR
EEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
LYVMLSENGYLRTIS
EEEEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]