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The map label for this gene is yhdH [H]

Identifier: 188527664

GI number: 188527664

Start: 866836

End: 868164

Strand: Reverse

Name: yhdH [H]

Synonym: HPSH_04430

Alternate gene names: 188527664

Gene position: 868164-866836 (Counterclockwise)

Preceding gene: 188527667

Following gene: 188527663

Centisome position: 53.97

GC content: 37.4

Gene sequence:

>1329_bases
ATGGGTAATCATTTTTCTAAATTAGGATTTGTTTTAGCCGCATTAGGAAGCGCGATAGGTTTAGGGCATATTTGGCGTTT
CCCCTATATGACTGGGGTGAGTGGTGGGGGTGCTTTTGTTTTATTGTTTTTATTTTTATCTTTAAGCGTTGGTGCAGCGA
TGTTTATCGCTGAAATGCTATTAGGACAAAGCACGCAAAAAAATGTAACAGAAGCTTTTAAAGAGCTTGACGCTAACCCT
AAAAAACGCTGGAAATACGCAGGGCTTTTGCTTGTTTCTGGACCTTTAATACTGACTTTTTATGGCACTATTTTAGGTTG
GGTGCTTTATTATTTAGTGAGTATTAGTTTTAATTTGCCTAATAGTATCCAAGCATCTGAACAAATCTTTAATGATACCT
TACAATCCATTGGGCTACAATCCATAGGGCTTCTTAGCGTTTTATTGATAACCGGATGGATTGTTTCTAGGGGGATTAAA
GAAGGCATTGAAAAACTCAATTTGGTTTTAATGCCCTTACTCTTTGCTACTTTTTTTGGTTTGCTTTTTTATGCGATGAG
CATGGATTCTTTTTCTAAAGCTTTTCATTTCATGTTTGATTTCAAACCAAAAGATTTGACTTCTCAAGTGTTCACTTATT
CCTTGGGGCAAGTTTTCTTTTCTTTAAGCATAGGTTTAGGAATCAATGTCACTTATGCTGCGGTTACTGATAAAACGCAG
AATTTGCTTAAAAGCACTATTTGGGTGGTTTTATCAGGAATTCTAATTTCTCTTGTGGCAGGGCTTATGATTTTCACTTT
TGTGTTTGAATATGGGGCGAATGTCTCACAAGGCACAGGGTTGATCTTCACTTCTTTACCGGTGGTTTTTGGCCAAATGG
GAGCGATAGGCATTCTTGTTTCAGTTCTTTTCTTGCTCGCGCTCGCTTTTGCTGGCATCACTTCTACGGTGGCTTTATTA
GAGCCAAGCGTGATGTATCTTACCGAAAGGTATCAATACTCTCGTTTTAAGGTTACTTGGGGTCTTGTAGCGCTAATTTT
TATCGTAGGCGTGGTGTTGATTTTTTCGCTTCATAACGATTATAAAGACTCACTCACTTTCTTTGAAAAAAGTCTTTTTG
ATTGGTTGGATTTTGCATCAAGCACCATTATCATGCCTTTAGGCGGGATGGCAACCTTTATTTTTATGGGCTGGGTTTTG
AAAAAAGAAAAATTGCGTCTTTTGAGTGCACACTTTTTAGGCCCTAAATTGTTTGCAACTTGGTATTTCTTGCTTAAATA
CATCACCCCTTTAATTGTGTTTTCCATTTGGTTGAGCAAGATTTATTAA

Upstream 100 bases:

>100_bases
GATCTTTAAAGATTTTAAAAAACTAATACAGCAATAGTTGGACGATTAAGGACATAGCTCTTTATTTTTAATCATTTACA
AGGAGTTTGGTAGTTAAGAT

Downstream 100 bases:

>100_bases
AATATTTAGCATGGGAAAATTTTCTAAATTAGGCTTTATTTTAGCCACTTTGGGTAGCTCTATCGGTTTAGGGCATATCT
GGCGCTTCCCTTATATGGTA

Product: sodium- and chloride-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MGNHFSKLGFVLAALGSAIGLGHIWRFPYMTGVSGGGAFVLLFLFLSLSVGAAMFIAEMLLGQSTQKNVTEAFKELDANP
KKRWKYAGLLLVSGPLILTFYGTILGWVLYYLVSISFNLPNSIQASEQIFNDTLQSIGLQSIGLLSVLLITGWIVSRGIK
EGIEKLNLVLMPLLFATFFGLLFYAMSMDSFSKAFHFMFDFKPKDLTSQVFTYSLGQVFFSLSIGLGINVTYAAVTDKTQ
NLLKSTIWVVLSGILISLVAGLMIFTFVFEYGANVSQGTGLIFTSLPVVFGQMGAIGILVSVLFLLALAFAGITSTVALL
EPSVMYLTERYQYSRFKVTWGLVALIFIVGVVLIFSLHNDYKDSLTFFEKSLFDWLDFASSTIIMPLGGMATFIFMGWVL
KKEKLRLLSAHFLGPKLFATWYFLLKYITPLIVFSIWLSKIY

Sequences:

>Translated_442_residues
MGNHFSKLGFVLAALGSAIGLGHIWRFPYMTGVSGGGAFVLLFLFLSLSVGAAMFIAEMLLGQSTQKNVTEAFKELDANP
KKRWKYAGLLLVSGPLILTFYGTILGWVLYYLVSISFNLPNSIQASEQIFNDTLQSIGLQSIGLLSVLLITGWIVSRGIK
EGIEKLNLVLMPLLFATFFGLLFYAMSMDSFSKAFHFMFDFKPKDLTSQVFTYSLGQVFFSLSIGLGINVTYAAVTDKTQ
NLLKSTIWVVLSGILISLVAGLMIFTFVFEYGANVSQGTGLIFTSLPVVFGQMGAIGILVSVLFLLALAFAGITSTVALL
EPSVMYLTERYQYSRFKVTWGLVALIFIVGVVLIFSLHNDYKDSLTFFEKSLFDWLDFASSTIIMPLGGMATFIFMGWVL
KKEKLRLLSAHFLGPKLFATWYFLLKYITPLIVFSIWLSKIY
>Mature_441_residues
GNHFSKLGFVLAALGSAIGLGHIWRFPYMTGVSGGGAFVLLFLFLSLSVGAAMFIAEMLLGQSTQKNVTEAFKELDANPK
KRWKYAGLLLVSGPLILTFYGTILGWVLYYLVSISFNLPNSIQASEQIFNDTLQSIGLQSIGLLSVLLITGWIVSRGIKE
GIEKLNLVLMPLLFATFFGLLFYAMSMDSFSKAFHFMFDFKPKDLTSQVFTYSLGQVFFSLSIGLGINVTYAAVTDKTQN
LLKSTIWVVLSGILISLVAGLMIFTFVFEYGANVSQGTGLIFTSLPVVFGQMGAIGILVSVLFLLALAFAGITSTVALLE
PSVMYLTERYQYSRFKVTWGLVALIFIVGVVLIFSLHNDYKDSLTFFEKSLFDWLDFASSTIIMPLGGMATFIFMGWVLK
KEKLRLLSAHFLGPKLFATWYFLLKYITPLIVFSIWLSKIY

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI134304856, Length=352, Percent_Identity=26.1363636363636, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI21361581, Length=409, Percent_Identity=24.9388753056235, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4507043, Length=401, Percent_Identity=25.4364089775561, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI289191351, Length=385, Percent_Identity=23.3766233766234, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI4557046, Length=385, Percent_Identity=23.3766233766234, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI289191377, Length=386, Percent_Identity=23.3160621761658, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI194018524, Length=293, Percent_Identity=25.938566552901, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI92859670, Length=436, Percent_Identity=24.3119266055046, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI188528618, Length=434, Percent_Identity=23.0414746543779, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI4507041, Length=388, Percent_Identity=22.680412371134, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI58219014, Length=309, Percent_Identity=26.537216828479, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI33354281, Length=328, Percent_Identity=23.4756097560976, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI171184408, Length=374, Percent_Identity=24.8663101604278, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI171184406, Length=374, Percent_Identity=24.8663101604278, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI171184404, Length=374, Percent_Identity=24.8663101604278, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI5032097, Length=346, Percent_Identity=24.8554913294798, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI21361693, Length=118, Percent_Identity=33.0508474576271, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17554804, Length=389, Percent_Identity=25.706940874036, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17555248, Length=116, Percent_Identity=36.2068965517241, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17136952, Length=485, Percent_Identity=24.7422680412371, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281364394, Length=485, Percent_Identity=24.7422680412371, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28574704, Length=485, Percent_Identity=24.7422680412371, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI17136950, Length=485, Percent_Identity=24.7422680412371, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28574702, Length=485, Percent_Identity=24.7422680412371, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24661428, Length=489, Percent_Identity=25.1533742331288, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281365034, Length=486, Percent_Identity=24.0740740740741, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI45551088, Length=375, Percent_Identity=26.4, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24652942, Length=375, Percent_Identity=26.4, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI19921936, Length=404, Percent_Identity=27.970297029703, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281363702, Length=471, Percent_Identity=24.6284501061571, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI19921352, Length=490, Percent_Identity=23.0612244897959, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24584353, Length=490, Percent_Identity=23.0612244897959, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24582567, Length=479, Percent_Identity=24.6346555323591, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24639853, Length=425, Percent_Identity=24.4705882352941, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24762620, Length=373, Percent_Identity=23.8605898123324, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI281363700, Length=325, Percent_Identity=26.1538461538462, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24639514, Length=518, Percent_Identity=22.3938223938224, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221329674, Length=518, Percent_Identity=22.5868725868726, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639516, Length=302, Percent_Identity=24.1721854304636, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45551183, Length=458, Percent_Identity=25.1091703056769, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI45550877, Length=388, Percent_Identity=25.7731958762887, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 49038; Mature: 48907

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GNHFSKLGFVLAALGSAIGLGHIWRFPYMTGVSGGGAFVLLFLFLSLSVGAAMFIAEML
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LGQSTQKNVTEAFKELDANPKKRWKYAGLLLVSGPLILTFYGTILGWVLYYLVSISFNLP
HCCCCHHHHHHHHHHCCCCHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
NSIQASEQIFNDTLQSIGLQSIGLLSVLLITGWIVSRGIKEGIEKLNLVLMPLLFATFFG
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLFYAMSMDSFSKAFHFMFDFKPKDLTSQVFTYSLGQVFFSLSIGLGINVTYAAVTDKTQ
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHH
NLLKSTIWVVLSGILISLVAGLMIFTFVFEYGANVSQGTGLIFTSLPVVFGQMGAIGILV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
SVLFLLALAFAGITSTVALLEPSVMYLTERYQYSRFKVTWGLVALIFIVGVVLIFSLHND
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YKDSLTFFEKSLFDWLDFASSTIIMPLGGMATFIFMGWVLKKEKLRLLSAHFLGPKLFAT
HHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
WYFLLKYITPLIVFSIWLSKIY
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]