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The map label for this gene is yocR [H]

Identifier: 188527663

GI number: 188527663

Start: 865497

End: 866825

Strand: Reverse

Name: yocR [H]

Synonym: HPSH_04425

Alternate gene names: 188527663

Gene position: 866825-865497 (Counterclockwise)

Preceding gene: 188527664

Following gene: 188527662

Centisome position: 53.89

GC content: 37.55

Gene sequence:

>1329_bases
ATGGGAAAATTTTCTAAATTAGGCTTTATTTTAGCCACTTTGGGTAGCTCTATCGGTTTAGGGCATATCTGGCGCTTCCC
TTATATGGTAGGCCATAATGGGGGGAGTGCGTTTGTGCTTTTATATCTAGCGCTAACCTTGAGTTTAGGCATTGCTATGC
TTTTAGTGGAAATGCTGATTGGGAATTTGGGTAAAAAAGATGTTGTTTCTAATTATCAAATACTAGATCCTAAAAGGAAA
AAACATTACCCTTTCACTTCTTTTTTTATTTTAGGCGGCCCTCTCATTTTATCCTTTTATGCGGTGGTGTTAGGCTGGGT
GCTTTACTATCTTTTTGTAGTAACTTTTGATTTGCCTAAAGATTTAGAACAAGCTAAAATGCAATTTAGCATGCTCCAAA
ATGGCAGTTTAATCTGGCCTGTTATTGGCTTTAGTGCATGCTTATTGCCGACAATATGGTTTGTTTCTAGGGGGATTGAA
GAGGGGATTGAAAAATTAAATGTAGTGCTCATGCCGTTATTGTTTGTGATTTTCATAGGGCTTTTAATCTATGCGATGAC
TTTAGAAAGCATGCCTAAAGCTTTGCACTTTTTATTTAATTTTGAGATTCAAAAGATTGATTTTAAGGTTGTTATGGACG
CTTTAGGGCAGATGTTCTTTTCTTTGAGTTTGGGGGTAGGCACGATTATTACTTATTCAGCTTTCACGCCCAAAAAAGAA
AATCTGTTCAAAAGCTCTTTATTGATTGTCTTGCCTGGTATTTTAATCTCTTTGATTGCCGGGGTGATGATTTTCACCTT
TGTGTTTGAATACCATGCAGACGTTTCTCAAGGGCCAGGGCTTGTTTTTATTTCCTTACCTTTGACCTTCGCTAAAATGG
GAACAAGCGGGCAGATTGTTTCGCTTTTTTTCTTTATGGCGCTTGTTTTTGCCGGAATCACTTCTACGGTTTCTTTGATA
GAGCCTTTAGCGCTTTATCTAATCAATCGTTTTAATTTTTCGCGCACTCAAGCGTCGCTATGGATAGGGATTGTTGTGTA
TGTTTTAGGCGTTTTAGTCATTCTTTCTATGAACGAACGATACGCTAAGTTTTTGAGTTTTGCTCATAAGAGCGTGTTTG
GGTGGCTGGATTTCATCACTTCTTCATTTTTAATGCCTTTGGGAGGCTTGTTTTCAGTCTTGTTTGTAGGATGGATTTTA
AATAAAAAGCGCTCTTTTTTAGCCACGAAGCATTTCTTTAATACAAACGCTTTTAAAGCGTGGCATTTTAGCGTTCGTTT
TATCGCGCCTGTAGTGATTTTAGCGATTTTCATCTTGCAATTTAAGTGA

Upstream 100 bases:

>100_bases
GGCCCTAAATTGTTTGCAACTTGGTATTTCTTGCTTAAATACATCACCCCTTTAATTGTGTTTTCCATTTGGTTGAGCAA
GATTTATTAAAATATTTAGC

Downstream 100 bases:

>100_bases
AATAAGGATGCTTGATGAAAGGCATTTTGCTCTTTATGATTTTTGTAGTTTGTCAGTTAGAAGGCAAAAAATTTTCACAA
GATAATTTTAAGGTGGATTA

Product: sodium- and chloride-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MGKFSKLGFILATLGSSIGLGHIWRFPYMVGHNGGSAFVLLYLALTLSLGIAMLLVEMLIGNLGKKDVVSNYQILDPKRK
KHYPFTSFFILGGPLILSFYAVVLGWVLYYLFVVTFDLPKDLEQAKMQFSMLQNGSLIWPVIGFSACLLPTIWFVSRGIE
EGIEKLNVVLMPLLFVIFIGLLIYAMTLESMPKALHFLFNFEIQKIDFKVVMDALGQMFFSLSLGVGTIITYSAFTPKKE
NLFKSSLLIVLPGILISLIAGVMIFTFVFEYHADVSQGPGLVFISLPLTFAKMGTSGQIVSLFFFMALVFAGITSTVSLI
EPLALYLINRFNFSRTQASLWIGIVVYVLGVLVILSMNERYAKFLSFAHKSVFGWLDFITSSFLMPLGGLFSVLFVGWIL
NKKRSFLATKHFFNTNAFKAWHFSVRFIAPVVILAIFILQFK

Sequences:

>Translated_442_residues
MGKFSKLGFILATLGSSIGLGHIWRFPYMVGHNGGSAFVLLYLALTLSLGIAMLLVEMLIGNLGKKDVVSNYQILDPKRK
KHYPFTSFFILGGPLILSFYAVVLGWVLYYLFVVTFDLPKDLEQAKMQFSMLQNGSLIWPVIGFSACLLPTIWFVSRGIE
EGIEKLNVVLMPLLFVIFIGLLIYAMTLESMPKALHFLFNFEIQKIDFKVVMDALGQMFFSLSLGVGTIITYSAFTPKKE
NLFKSSLLIVLPGILISLIAGVMIFTFVFEYHADVSQGPGLVFISLPLTFAKMGTSGQIVSLFFFMALVFAGITSTVSLI
EPLALYLINRFNFSRTQASLWIGIVVYVLGVLVILSMNERYAKFLSFAHKSVFGWLDFITSSFLMPLGGLFSVLFVGWIL
NKKRSFLATKHFFNTNAFKAWHFSVRFIAPVVILAIFILQFK
>Mature_441_residues
GKFSKLGFILATLGSSIGLGHIWRFPYMVGHNGGSAFVLLYLALTLSLGIAMLLVEMLIGNLGKKDVVSNYQILDPKRKK
HYPFTSFFILGGPLILSFYAVVLGWVLYYLFVVTFDLPKDLEQAKMQFSMLQNGSLIWPVIGFSACLLPTIWFVSRGIEE
GIEKLNVVLMPLLFVIFIGLLIYAMTLESMPKALHFLFNFEIQKIDFKVVMDALGQMFFSLSLGVGTIITYSAFTPKKEN
LFKSSLLIVLPGILISLIAGVMIFTFVFEYHADVSQGPGLVFISLPLTFAKMGTSGQIVSLFFFMALVFAGITSTVSLIE
PLALYLINRFNFSRTQASLWIGIVVYVLGVLVILSMNERYAKFLSFAHKSVFGWLDFITSSFLMPLGGLFSVLFVGWILN
KKRSFLATKHFFNTNAFKAWHFSVRFIAPVVILAIFILQFK

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI21361581, Length=492, Percent_Identity=25.2032520325203, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI188528618, Length=494, Percent_Identity=23.2793522267206, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI171184408, Length=496, Percent_Identity=23.991935483871, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI171184406, Length=496, Percent_Identity=23.991935483871, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI171184404, Length=496, Percent_Identity=23.991935483871, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI4507043, Length=382, Percent_Identity=24.869109947644, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI58219014, Length=297, Percent_Identity=25.9259259259259, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI7657587, Length=459, Percent_Identity=23.0936819172113, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI289191377, Length=395, Percent_Identity=23.7974683544304, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI33354281, Length=334, Percent_Identity=26.0479041916168, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI92859670, Length=430, Percent_Identity=23.7209302325581, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI289191351, Length=395, Percent_Identity=23.7974683544304, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4557046, Length=395, Percent_Identity=23.7974683544304, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4507041, Length=387, Percent_Identity=24.031007751938, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI197276623, Length=343, Percent_Identity=25.3644314868805, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI54607094, Length=343, Percent_Identity=25.3644314868805, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI134304856, Length=335, Percent_Identity=24.4776119402985, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI21361693, Length=123, Percent_Identity=34.1463414634146, Blast_Score=74, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17554804, Length=362, Percent_Identity=28.7292817679558, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71998244, Length=336, Percent_Identity=26.7857142857143, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI133952791, Length=277, Percent_Identity=24.5487364620939, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17569475, Length=387, Percent_Identity=23.2558139534884, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17555248, Length=121, Percent_Identity=32.2314049586777, Blast_Score=65, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24661428, Length=484, Percent_Identity=25, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI281365034, Length=489, Percent_Identity=24.9488752556237, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24652942, Length=472, Percent_Identity=25.4237288135593, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI45551088, Length=472, Percent_Identity=25.4237288135593, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI19921352, Length=497, Percent_Identity=24.1448692152917, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24584353, Length=497, Percent_Identity=24.1448692152917, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24762620, Length=376, Percent_Identity=27.3936170212766, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI19921936, Length=487, Percent_Identity=24.2299794661191, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17136952, Length=366, Percent_Identity=23.224043715847, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI281364394, Length=366, Percent_Identity=24.0437158469945, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28574704, Length=366, Percent_Identity=24.0437158469945, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17136950, Length=366, Percent_Identity=24.0437158469945, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28574702, Length=366, Percent_Identity=24.0437158469945, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI221329674, Length=509, Percent_Identity=22.9862475442043, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24639514, Length=509, Percent_Identity=22.9862475442043, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281363702, Length=477, Percent_Identity=24.1090146750524, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24639516, Length=304, Percent_Identity=27.3026315789474, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24582567, Length=474, Percent_Identity=23.6286919831224, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24655079, Length=301, Percent_Identity=24.9169435215947, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24654186, Length=239, Percent_Identity=27.1966527196653, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45551183, Length=224, Percent_Identity=27.6785714285714, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI281364136, Length=283, Percent_Identity=27.208480565371, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI45550877, Length=277, Percent_Identity=25.2707581227437, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 49543; Mature: 49412

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GKFSKLGFILATLGSSIGLGHIWRFPYMVGHNGGSAFVLLYLALTLSLGIAMLLVEMLI
CCHHHHHHHHHHHCCCCCCCHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GNLGKKDVVSNYQILDPKRKKHYPFTSFFILGGPLILSFYAVVLGWVLYYLFVVTFDLPK
CCCCCHHHHCCCEECCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
DLEQAKMQFSMLQNGSLIWPVIGFSACLLPTIWFVSRGIEEGIEKLNVVLMPLLFVIFIG
HHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLIYAMTLESMPKALHFLFNFEIQKIDFKVVMDALGQMFFSLSLGVGTIITYSAFTPKKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEECCCCCCHH
NLFKSSLLIVLPGILISLIAGVMIFTFVFEYHADVSQGPGLVFISLPLTFAKMGTSGQIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHCCCCCHHH
SLFFFMALVFAGITSTVSLIEPLALYLINRFNFSRTQASLWIGIVVYVLGVLVILSMNER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
YAKFLSFAHKSVFGWLDFITSSFLMPLGGLFSVLFVGWILNKKRSFLATKHFFNTNAFKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEH
WHFSVRFIAPVVILAIFILQFK
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]