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The map label for this gene is hypE [H]

Identifier: 188526856

GI number: 188526856

Start: 42325

End: 43323

Strand: Reverse

Name: hypE [H]

Synonym: HPSH_00230

Alternate gene names: 188526856

Gene position: 43323-42325 (Counterclockwise)

Preceding gene: 188526857

Following gene: 188526855

Centisome position: 2.69

GC content: 41.14

Gene sequence:

>999_bases
ATGGATAGCGTAACTCTAGCATGCGGGAACGGAGGGAAAGAAACAAACGCTTTAATTGAGCGAGTCTTTATGCCCTATTT
AAAAGAATTTATCGTTGCGTTTGATGAAGACGCCCCTAAATTTAAAGCTAGTGGGGAATATTGCGTGAGCACGGATAGTT
TTGTCATCACGCCCTTAATTTTTAATGGGGGCGATATAGGCAAGCTTTGCGTTTGCGGGAGCGCGAATGATGTGAGCGTG
CAAGGGGGCGAACCTTTGTATTTGAATATGGGTTTTATTTTAGAAGAAGGCTTAGAAATCCCTCTTTTAAAACAAATTTT
ACAATCCATACAAAAAGAATTGCTTAAAGCCAACCTGAAACTCCTCTCCCTAGACACTAAAGTCGTGCCAAAGGGGAGCG
TGGATAAGCTTTTTATCAACACAACCTGTATTGGTAAAACCATCAAGCCAGGGATTTCTTCACGCTATTTAAAACAAGGC
CAAGCCATTATCATAAGCGACACTATCGCCAATCATGGGGCAAGCTTGTTTGCGATGCGCCATGAAATCAAACTTAAAAC
TAATCTAGAAAGCGATTGCCAACTGCTCTATCCCTTATTAAAACCCCTATTTTTAAGCGATCTTAAAATCCATGCTTTAA
GAGATGCGACCAGGGGCGGGTTAGCGAGCGTGCTGAATGAATGGGCGAACAGCTCCAAAGTGAAAATCGTTATAGAAGAA
GAAAAAATCCCCTTAAAAGAAGAAACTAAAGGGATTTGTGAGATTTTAGGGCTAGAACCCTACGCGTTAGCCAATGAGGG
GGTGTTTGTTTTAGCGATCAATCAAAAAGACGCCCCTAAAGCCTTAGAAATTTTAAAAAGTAACGAAAAAGCTAAAAACG
CTTGCGTGATTGGCGAGGTTTTTGAAAACCCTTATCCTAGCGTGGTTTTAAAGAACGCATGGGGTTTTGAAAGGATTTTA
GAGATGCCAGAAGGCGAATTATTGCCTAGGATTTGTTAA

Upstream 100 bases:

>100_bases
ATTTTTTCCACAAGCATTTCCCTCCTAACGATAGCAGTATCCCTATCGGTCAAGCCTTAATGGCGTATTTCAACCCTACA
ATCATTAAAAAAGGATAAAA

Downstream 100 bases:

>100_bases
GGCTAAGGCGCTTTTTAAAACTCCACCGCACCCCTACCCTCTAAAATCACTATAATCAATCTATTTGAGAAAACTTGCAA
TAAAAGAGGGTTAATGGCGG

Product: hydrogenase expression/formation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MDSVTLACGNGGKETNALIERVFMPYLKEFIVAFDEDAPKFKASGEYCVSTDSFVITPLIFNGGDIGKLCVCGSANDVSV
QGGEPLYLNMGFILEEGLEIPLLKQILQSIQKELLKANLKLLSLDTKVVPKGSVDKLFINTTCIGKTIKPGISSRYLKQG
QAIIISDTIANHGASLFAMRHEIKLKTNLESDCQLLYPLLKPLFLSDLKIHALRDATRGGLASVLNEWANSSKVKIVIEE
EKIPLKEETKGICEILGLEPYALANEGVFVLAINQKDAPKALEILKSNEKAKNACVIGEVFENPYPSVVLKNAWGFERIL
EMPEGELLPRIC

Sequences:

>Translated_332_residues
MDSVTLACGNGGKETNALIERVFMPYLKEFIVAFDEDAPKFKASGEYCVSTDSFVITPLIFNGGDIGKLCVCGSANDVSV
QGGEPLYLNMGFILEEGLEIPLLKQILQSIQKELLKANLKLLSLDTKVVPKGSVDKLFINTTCIGKTIKPGISSRYLKQG
QAIIISDTIANHGASLFAMRHEIKLKTNLESDCQLLYPLLKPLFLSDLKIHALRDATRGGLASVLNEWANSSKVKIVIEE
EKIPLKEETKGICEILGLEPYALANEGVFVLAINQKDAPKALEILKSNEKAKNACVIGEVFENPYPSVVLKNAWGFERIL
EMPEGELLPRIC
>Mature_332_residues
MDSVTLACGNGGKETNALIERVFMPYLKEFIVAFDEDAPKFKASGEYCVSTDSFVITPLIFNGGDIGKLCVCGSANDVSV
QGGEPLYLNMGFILEEGLEIPLLKQILQSIQKELLKANLKLLSLDTKVVPKGSVDKLFINTTCIGKTIKPGISSRYLKQG
QAIIISDTIANHGASLFAMRHEIKLKTNLESDCQLLYPLLKPLFLSDLKIHALRDATRGGLASVLNEWANSSKVKIVIEE
EKIPLKEETKGICEILGLEPYALANEGVFVLAINQKDAPKALEILKSNEKAKNACVIGEVFENPYPSVVLKNAWGFERIL
EMPEGELLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=341, Percent_Identity=41.0557184750733, Blast_Score=245, Evalue=3e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 36399; Mature: 36399

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSVTLACGNGGKETNALIERVFMPYLKEFIVAFDEDAPKFKASGEYCVSTDSFVITPLI
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCEEEEEEE
FNGGDIGKLCVCGSANDVSVQGGEPLYLNMGFILEEGLEIPLLKQILQSIQKELLKANLK
ECCCCCCEEEEECCCCCEEECCCCEEEEEECHHHHCCCCCHHHHHHHHHHHHHHHHCCCE
LLSLDTKVVPKGSVDKLFINTTCIGKTIKPGISSRYLKQGQAIIISDTIANHGASLFAMR
EEEECCEECCCCCCCEEEEEEEECCCCCCCCCHHHHHHCCCEEEEECCHHHCCCCEEEEE
HEIKLKTNLESDCQLLYPLLKPLFLSDLKIHALRDATRGGLASVLNEWANSSKVKIVIEE
EEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHCCCCEEEEEEEC
EKIPLKEETKGICEILGLEPYALANEGVFVLAINQKDAPKALEILKSNEKAKNACVIGEV
CCCCCHHHHHHHHHHHCCCCEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCCEEEEEHH
FENPYPSVVLKNAWGFERILEMPEGELLPRIC
HCCCCCCEEEECCCCHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MDSVTLACGNGGKETNALIERVFMPYLKEFIVAFDEDAPKFKASGEYCVSTDSFVITPLI
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCEEEEEEE
FNGGDIGKLCVCGSANDVSVQGGEPLYLNMGFILEEGLEIPLLKQILQSIQKELLKANLK
ECCCCCCEEEEECCCCCEEECCCCEEEEEECHHHHCCCCCHHHHHHHHHHHHHHHHCCCE
LLSLDTKVVPKGSVDKLFINTTCIGKTIKPGISSRYLKQGQAIIISDTIANHGASLFAMR
EEEECCEECCCCCCCEEEEEEEECCCCCCCCCHHHHHHCCCEEEEECCHHHCCCCEEEEE
HEIKLKTNLESDCQLLYPLLKPLFLSDLKIHALRDATRGGLASVLNEWANSSKVKIVIEE
EEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHCCCCEEEEEEEC
EKIPLKEETKGICEILGLEPYALANEGVFVLAINQKDAPKALEILKSNEKAKNACVIGEV
CCCCCHHHHHHHHHHHCCCCEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCCEEEEEHH
FENPYPSVVLKNAWGFERILEMPEGELLPRIC
HCCCCCCEEEECCCCHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1849603; 9278503 [H]