| Definition | Helicobacter pylori Shi470, complete genome. |
|---|---|
| Accession | NC_010698 |
| Length | 1,608,548 |
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The map label for this gene is hypF [H]
Identifier: 188526857
GI number: 188526857
Start: 43326
End: 45578
Strand: Reverse
Name: hypF [H]
Synonym: HPSH_00235
Alternate gene names: 188526857
Gene position: 45578-43326 (Counterclockwise)
Preceding gene: 188526858
Following gene: 188526856
Centisome position: 2.83
GC content: 40.57
Gene sequence:
>2253_bases TTGAATAAAATCACGCTTTTTGGCGTGGTTCAAGGCGTGGGCATGCGCCCTTTTATTTATACCCTAGCTCAAAAATTAGA GCTTGTAGGCTTTGTGCGTAACACCCAAGCGGCTTTAGAAATCATCTTACCCGCTCATAAAACAGAGTCTTTTTTAAACG CCCTAAAAAAAGGGTTGCCCCCTTTAGCGTTGGTTGAAAAAATCATTATTAGCCCTTATGATAAAACGCTCAAATCCAAT GATTTTAGGATTTTAGAAAGCAAGAACCACTCTTTGAATTTGCTCAGTCAAATCCCTAAAGATTTAGGCGTGTGTGAAGA TTGCTTGCGCGAAATTAGGGATAAAAACTCCCCCTATTTCCATTACGCTTTCAATTCTTGTGCGAAATGCGGGGCGAGAT ACAGCCTTTTAAACGCTTTGCCCTATGACAGAGAAAACTCCGCCCTAAAGCCTTTCAAACTCTGTGAGTTTTGCGCATTC GTTTATAAAGACGCCAATAACAAACGCTTCCACATTCAAGGCATCAGCTGCAAAAAGTGCGGTATTACGCTCAGTTACAA GCGATTCAAAAATGATGACGCTCTTTTAGAATGCGCTAAAGACATTCAAAAAGGTAAAATCATCGCTCTTAAAGGTTTGG GAGGCTTTGCCCTCTTGTGCGATGCGAGGAATTTTCAAACCATAGAAAGATTACGGCTTTTAAAAAACCGCCCCCTAAAA CCTTTCGCGCTCATGTTTAAAGATCTAAACACAGCCAAACAGCATGCGTTTTTGAGCGTATTAGAATGCGAAAGCTTAAA TTCCACAAGCGCCCCCATTCTTTTAGCGCGTAAAAAACCGAACACGCAATTAGCCCCTAATATCGCTAAAAACTCCCCCT TTTATGGCGTCATCCTACCCTATACCCCTTTGCATGCTTTATTGCTGGATTTATTGGATTTCCCCATTATATTCACGAGC GCGAATTTCAGCTCCCTCCCTTTAGCGAGCGATGAGGCTGATATTGATTCCTTGAGTTTCATTTTTGATTTTAAACTCAC GCACAATCGCGCTATCATTCACAGGATTGATGATAGTATTGCGCAACATGTGGATAATGCGATTCGCCCCATGCGTTTGG CTAGGGGGTTTGCCCCACTTTATCTCACTTTGCCTAAACGCTCTAATGATTCGCAAAAAAAGATTTTAGCGCTTGGAGCG GAGCAAAAAGGGCATTTTAGCTTATTGGATAGTGAAACTTCCATTCTTTTACTCTCGCCTTTTTGTGGGGATTTGAGCGT TTTAGAAAATGAAAAACACTTTAAAGAAACTTTGAATTTTTTCTTAAAAACCTATGATTTTAAACCCACCATTTTGGCTT GCGATAAGCATCAAAACTACACCACCACTCAAATGGCTTATGGTTTTAATACGCCCTTGTTGCAAGTCCAGCACCACCAT GCCCACTTTTTAGCGAGCATTTTAGACGCATTATTACAAGACCCGCACTTAAACAACCCTTTTATAGGCATCATCTGGGA TGGGAGTGGGGCTTATGAAAATAAGATTTATGGGGCGGAGTGTTTTGTGGGGGATTTTGAACGCATTGAAGAAGTGGCTA GATTTGAAGAATTTCTGCTTTTAGGGGGGGAAAAAGCGATCAAAGAGCCTAAACGCCTGGTTTTAGAAATCGCTTTAAAA CACCAACTCAACAAGCTTTTAGAGCGCGTTCAAAAACATTTTAAAGAAGACGAATTGGAAATTTTTCAGCAAATGCATGA CAGAAAAATTCAAAGCATAGCTACCAATTCCATAGGGCGTTTGTTTGATATAGTAGCGTTTAGTTTGGATTTAACAGGAA CGATTAGCTTTGAAGCAGAGAGCGGGCAGGTTTTAGAAAATCTAGCCTTACAAAGCGATGAGATCGCTTTTTACCCTTTT AAAATCAAAAACAGCGTGGTGTGTTTGAAAGAATTTTATCAAGCGTTTGAAAAGGATTTGGGCGTTTTAGAGCCCAAACG CATCGCTAAGAAATTTTTTAACAGCCTAGTAGAAATCATTACCGCTTTGATTGCACCTTTTAAAGAGCATGTGGTGGTGT GCAGTGGGGGCGTGTTTTGCAACCAATTATTATGCGAACAATTAGCCAAACGATTGAGAGGGCTAAAAAGGCAGTATTTT TTCCACAAGCATTTCCCTCCTAACGATAGCAGTATCCCTATCGGTCAAGCCTTAATGGCGTATTTCAACCCTACAATCAT TAAAAAAGGATAA
Upstream 100 bases:
>100_bases AAACCTTAAAACAACACACGCCCTTAGAAGTGATAGGGGTTGATTGCAATACTTTAATCAAACAGCATGGAAGCTTGCAT TGTGTAACGATGCAACTTTA
Downstream 100 bases:
>100_bases AAATGGATAGCGTAACTCTAGCATGCGGGAACGGAGGGAAAGAAACAAACGCTTTAATTGAGCGAGTCTTTATGCCCTAT TTAAAAGAATTTATCGTTGC
Product: transcriptional regulator (hypF)
Products: NA
Alternate protein names: Carbamoyl phosphate-converting enzyme hypF; [NiFe]-hydrogenase maturation factor hypF; Hydrogenase maturation protein hypF [H]
Number of amino acids: Translated: 750; Mature: 750
Protein sequence:
>750_residues MNKITLFGVVQGVGMRPFIYTLAQKLELVGFVRNTQAALEIILPAHKTESFLNALKKGLPPLALVEKIIISPYDKTLKSN DFRILESKNHSLNLLSQIPKDLGVCEDCLREIRDKNSPYFHYAFNSCAKCGARYSLLNALPYDRENSALKPFKLCEFCAF VYKDANNKRFHIQGISCKKCGITLSYKRFKNDDALLECAKDIQKGKIIALKGLGGFALLCDARNFQTIERLRLLKNRPLK PFALMFKDLNTAKQHAFLSVLECESLNSTSAPILLARKKPNTQLAPNIAKNSPFYGVILPYTPLHALLLDLLDFPIIFTS ANFSSLPLASDEADIDSLSFIFDFKLTHNRAIIHRIDDSIAQHVDNAIRPMRLARGFAPLYLTLPKRSNDSQKKILALGA EQKGHFSLLDSETSILLLSPFCGDLSVLENEKHFKETLNFFLKTYDFKPTILACDKHQNYTTTQMAYGFNTPLLQVQHHH AHFLASILDALLQDPHLNNPFIGIIWDGSGAYENKIYGAECFVGDFERIEEVARFEEFLLLGGEKAIKEPKRLVLEIALK HQLNKLLERVQKHFKEDELEIFQQMHDRKIQSIATNSIGRLFDIVAFSLDLTGTISFEAESGQVLENLALQSDEIAFYPF KIKNSVVCLKEFYQAFEKDLGVLEPKRIAKKFFNSLVEIITALIAPFKEHVVVCSGGVFCNQLLCEQLAKRLRGLKRQYF FHKHFPPNDSSIPIGQALMAYFNPTIIKKG
Sequences:
>Translated_750_residues MNKITLFGVVQGVGMRPFIYTLAQKLELVGFVRNTQAALEIILPAHKTESFLNALKKGLPPLALVEKIIISPYDKTLKSN DFRILESKNHSLNLLSQIPKDLGVCEDCLREIRDKNSPYFHYAFNSCAKCGARYSLLNALPYDRENSALKPFKLCEFCAF VYKDANNKRFHIQGISCKKCGITLSYKRFKNDDALLECAKDIQKGKIIALKGLGGFALLCDARNFQTIERLRLLKNRPLK PFALMFKDLNTAKQHAFLSVLECESLNSTSAPILLARKKPNTQLAPNIAKNSPFYGVILPYTPLHALLLDLLDFPIIFTS ANFSSLPLASDEADIDSLSFIFDFKLTHNRAIIHRIDDSIAQHVDNAIRPMRLARGFAPLYLTLPKRSNDSQKKILALGA EQKGHFSLLDSETSILLLSPFCGDLSVLENEKHFKETLNFFLKTYDFKPTILACDKHQNYTTTQMAYGFNTPLLQVQHHH AHFLASILDALLQDPHLNNPFIGIIWDGSGAYENKIYGAECFVGDFERIEEVARFEEFLLLGGEKAIKEPKRLVLEIALK HQLNKLLERVQKHFKEDELEIFQQMHDRKIQSIATNSIGRLFDIVAFSLDLTGTISFEAESGQVLENLALQSDEIAFYPF KIKNSVVCLKEFYQAFEKDLGVLEPKRIAKKFFNSLVEIITALIAPFKEHVVVCSGGVFCNQLLCEQLAKRLRGLKRQYF FHKHFPPNDSSIPIGQALMAYFNPTIIKKG >Mature_750_residues MNKITLFGVVQGVGMRPFIYTLAQKLELVGFVRNTQAALEIILPAHKTESFLNALKKGLPPLALVEKIIISPYDKTLKSN DFRILESKNHSLNLLSQIPKDLGVCEDCLREIRDKNSPYFHYAFNSCAKCGARYSLLNALPYDRENSALKPFKLCEFCAF VYKDANNKRFHIQGISCKKCGITLSYKRFKNDDALLECAKDIQKGKIIALKGLGGFALLCDARNFQTIERLRLLKNRPLK PFALMFKDLNTAKQHAFLSVLECESLNSTSAPILLARKKPNTQLAPNIAKNSPFYGVILPYTPLHALLLDLLDFPIIFTS ANFSSLPLASDEADIDSLSFIFDFKLTHNRAIIHRIDDSIAQHVDNAIRPMRLARGFAPLYLTLPKRSNDSQKKILALGA EQKGHFSLLDSETSILLLSPFCGDLSVLENEKHFKETLNFFLKTYDFKPTILACDKHQNYTTTQMAYGFNTPLLQVQHHH AHFLASILDALLQDPHLNNPFIGIIWDGSGAYENKIYGAECFVGDFERIEEVARFEEFLLLGGEKAIKEPKRLVLEIALK HQLNKLLERVQKHFKEDELEIFQQMHDRKIQSIATNSIGRLFDIVAFSLDLTGTISFEAESGQVLENLALQSDEIAFYPF KIKNSVVCLKEFYQAFEKDLGVLEPKRIAKKFFNSLVEIITALIAPFKEHVVVCSGGVFCNQLLCEQLAKRLRGLKRQYF FHKHFPPNDSSIPIGQALMAYFNPTIIKKG
Specific function: Along with hypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carb
COG id: COG0068
COG function: function code O; Hydrogenase maturation factor
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 YrdC-like domain [H]
Homologues:
Organism=Escherichia coli, GI2367152, Length=755, Percent_Identity=32.0529801324503, Blast_Score=304, Evalue=1e-83,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001792 - InterPro: IPR017968 - InterPro: IPR004421 - InterPro: IPR017945 - InterPro: IPR006070 - InterPro: IPR011125 [H]
Pfam domain/function: PF00708 Acylphosphatase; PF01300 Sua5_yciO_yrdC; PF07503 zf-HYPF [H]
EC number: NA
Molecular weight: Translated: 84978; Mature: 84978
Theoretical pI: Translated: 8.72; Mature: 8.72
Prosite motif: PS00150 ACYLPHOSPHATASE_1 ; PS51160 ACYLPHOSPHATASE_3 ; PS51163 YRDC
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.4 %Cys (Translated Protein) 0.9 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 2.4 %Cys (Mature Protein) 0.9 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNKITLFGVVQGVGMRPFIYTLAQKLELVGFVRNTQAALEIILPAHKTESFLNALKKGLP CCCEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHEEECCHHHHHHHHHHHHCCC PLALVEKIIISPYDKTLKSNDFRILESKNHSLNLLSQIPKDLGVCEDCLREIRDKNSPYF HHHHHHHHHHCCCHHHHCCCCEEEEECCCCCHHHHHHCCHHCCHHHHHHHHHHCCCCCEE HYAFNSCAKCGARYSLLNALPYDRENSALKPFKLCEFCAFVYKDANNKRFHIQGISCKKC EEHHHHHHHHCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHC GITLSYKRFKNDDALLECAKDIQKGKIIALKGLGGFALLCDARNFQTIERLRLLKNRPLK CCEEEHHHCCCCHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCHHHHHHHHHHHCCCCC PFALMFKDLNTAKQHAFLSVLECESLNSTSAPILLARKKPNTQLAPNIAKNSPFYGVILP HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEECC YTPLHALLLDLLDFPIIFTSANFSSLPLASDEADIDSLSFIFDFKLTHNRAIIHRIDDSI CCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHH AQHVDNAIRPMRLARGFAPLYLTLPKRSNDSQKKILALGAEQKGHFSLLDSETSILLLSP HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHEEEECCCCCCCEEEECCCCCEEEECC FCGDLSVLENEKHFKETLNFFLKTYDFKPTILACDKHQNYTTTQMAYGFNTPLLQVQHHH CCCCHHHHCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEEEECCCCCEEEEHHHH AHFLASILDALLQDPHLNNPFIGIIWDGSGAYENKIYGAECFVGDFERIEEVARFEEFLL HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH LGGEKAIKEPKRLVLEIALKHQLNKLLERVQKHFKEDELEIFQQMHDRKIQSIATNSIGR CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH LFDIVAFSLDLTGTISFEAESGQVLENLALQSDEIAFYPFKIKNSVVCLKEFYQAFEKDL HHHHHHHHEECEEEEEEECCCCHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHC GVLEPKRIAKKFFNSLVEIITALIAPFKEHVVVCSGGVFCNQLLCEQLAKRLRGLKRQYF CCCCHHHHHHHHHHHHHHHHHHHHHCHHHCEEEECCCHHHHHHHHHHHHHHHHHHHHHHH FHKHFPPNDSSIPIGQALMAYFNPTIIKKG HHCCCCCCCCCCCHHHHHHHHHCCEEEECC >Mature Secondary Structure MNKITLFGVVQGVGMRPFIYTLAQKLELVGFVRNTQAALEIILPAHKTESFLNALKKGLP CCCEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHEEECCHHHHHHHHHHHHCCC PLALVEKIIISPYDKTLKSNDFRILESKNHSLNLLSQIPKDLGVCEDCLREIRDKNSPYF HHHHHHHHHHCCCHHHHCCCCEEEEECCCCCHHHHHHCCHHCCHHHHHHHHHHCCCCCEE HYAFNSCAKCGARYSLLNALPYDRENSALKPFKLCEFCAFVYKDANNKRFHIQGISCKKC EEHHHHHHHHCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHC GITLSYKRFKNDDALLECAKDIQKGKIIALKGLGGFALLCDARNFQTIERLRLLKNRPLK CCEEEHHHCCCCHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCHHHHHHHHHHHCCCCC PFALMFKDLNTAKQHAFLSVLECESLNSTSAPILLARKKPNTQLAPNIAKNSPFYGVILP HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEECC YTPLHALLLDLLDFPIIFTSANFSSLPLASDEADIDSLSFIFDFKLTHNRAIIHRIDDSI CCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHH AQHVDNAIRPMRLARGFAPLYLTLPKRSNDSQKKILALGAEQKGHFSLLDSETSILLLSP HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHEEEECCCCCCCEEEECCCCCEEEECC FCGDLSVLENEKHFKETLNFFLKTYDFKPTILACDKHQNYTTTQMAYGFNTPLLQVQHHH CCCCHHHHCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEEEECCCCCEEEEHHHH AHFLASILDALLQDPHLNNPFIGIIWDGSGAYENKIYGAECFVGDFERIEEVARFEEFLL HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH LGGEKAIKEPKRLVLEIALKHQLNKLLERVQKHFKEDELEIFQQMHDRKIQSIATNSIGR CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH LFDIVAFSLDLTGTISFEAESGQVLENLALQSDEIAFYPFKIKNSVVCLKEFYQAFEKDL HHHHHHHHEECEEEEEEECCCCHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHC GVLEPKRIAKKFFNSLVEIITALIAPFKEHVVVCSGGVFCNQLLCEQLAKRLRGLKRQYF CCCCHHHHHHHHHHHHHHHHHHHHHCHHHCEEEECCCHHHHHHHHHHHHHHHHHHHHHHH FHKHFPPNDSSIPIGQALMAYFNPTIIKKG HHCCCCCCCCCCCHHHHHHHHHCCEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8590279; 8905231 [H]