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The map label for this gene is 187935218

Identifier: 187935218

GI number: 187935218

Start: 3031509

End: 3032372

Strand: Reverse

Name: 187935218

Synonym: CLL_A2950

Alternate gene names: NA

Gene position: 3032372-3031509 (Counterclockwise)

Preceding gene: 187932525

Following gene: 187934460

Centisome position: 79.79

GC content: 26.27

Gene sequence:

>864_bases
ATGAAAATAACCACATTAATAGAAAATACACAGGATAAGGATGAGAAGCTAAAAAATGAACATGGTCTTTCTATGTTTAT
TGAAGGAAATAATTGCAATGTCTTATTCGATACTGGAAAAACAGGAGATTTTATTGAAAATGCTAAAAAACTAAATATTG
ATCTTAAGAAAACTGATATTTTAGTTTTAAGTCATGCTCATTATGATCATTGTGGTGGGGTTAAAAGATTACTAGAAACC
TATGATATAAAACCTAAACTTGTAGTAAGTAAGCATTTTTTTAATAGAACAGATAAGTATCATTATTCTGATGGAAGTCT
AAAATCAGATTTTTCAAAAGAACCTGGATATGCATATATAGGAACTGATTTTGATAAAAAATATGTTGAAGATAAAGGAA
TTAGAATAGAGAGTTTAGAAAAAGATGTTTTAGAAATATGTGATAATGTTTTTGTATGTTCTAATTTTAATAAATACTAT
GATTTTGAAAAAGTAAACCCTAACATGCAACGCAAAGTTAATGATGAATATATAATTGATACATTTGACGAAGAAGTAGC
ATTAGGAATAAAAACTAAAAAAGGATTAGTTATATTATTAGGATGTGCACATCCAGGATTTTTAAATATGGTAAAAACTA
TAGAAGAAAGAACTAATGAAAAGATAGTAGGTATAATAGGTGGTACACATCTTATAGAAGCTGATGATGAGAGAATAAAA
AAATCAGTTGATTATTTAAATAAATCAGGAGTTGAACTATTAGGATTATCACACTGTACTGGTGAAAAAGCAGTTGAAAT
TTTTAATAAGGAATGTAAAACTTCATTTACCAATAGAACAGGTACAATAGTAGAATTAGATTAA

Upstream 100 bases:

>100_bases
TCTGGATTAGAAGAAATTACAGCAACGGTTCAAGAACTTAATTCTACTGCAGTGCTTCTAAAAGAATTTGCCGCTACAAT
ATAAAATGGGAGATGTTAAT

Downstream 100 bases:

>100_bases
TTTTTAAACTATAAATCAATTAATAAATTTAATGAGCTATCTTGGAATGATTTTTTAAATCATTAGGTGACGATGGCTCT
TTTTTTATTTACATAATAAT

Product: beta-lactamase domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKITTLIENTQDKDEKLKNEHGLSMFIEGNNCNVLFDTGKTGDFIENAKKLNIDLKKTDILVLSHAHYDHCGGVKRLLET
YDIKPKLVVSKHFFNRTDKYHYSDGSLKSDFSKEPGYAYIGTDFDKKYVEDKGIRIESLEKDVLEICDNVFVCSNFNKYY
DFEKVNPNMQRKVNDEYIIDTFDEEVALGIKTKKGLVILLGCAHPGFLNMVKTIEERTNEKIVGIIGGTHLIEADDERIK
KSVDYLNKSGVELLGLSHCTGEKAVEIFNKECKTSFTNRTGTIVELD

Sequences:

>Translated_287_residues
MKITTLIENTQDKDEKLKNEHGLSMFIEGNNCNVLFDTGKTGDFIENAKKLNIDLKKTDILVLSHAHYDHCGGVKRLLET
YDIKPKLVVSKHFFNRTDKYHYSDGSLKSDFSKEPGYAYIGTDFDKKYVEDKGIRIESLEKDVLEICDNVFVCSNFNKYY
DFEKVNPNMQRKVNDEYIIDTFDEEVALGIKTKKGLVILLGCAHPGFLNMVKTIEERTNEKIVGIIGGTHLIEADDERIK
KSVDYLNKSGVELLGLSHCTGEKAVEIFNKECKTSFTNRTGTIVELD
>Mature_287_residues
MKITTLIENTQDKDEKLKNEHGLSMFIEGNNCNVLFDTGKTGDFIENAKKLNIDLKKTDILVLSHAHYDHCGGVKRLLET
YDIKPKLVVSKHFFNRTDKYHYSDGSLKSDFSKEPGYAYIGTDFDKKYVEDKGIRIESLEKDVLEICDNVFVCSNFNKYY
DFEKVNPNMQRKVNDEYIIDTFDEEVALGIKTKKGLVILLGCAHPGFLNMVKTIEERTNEKIVGIIGGTHLIEADDERIK
KSVDYLNKSGVELLGLSHCTGEKAVEIFNKECKTSFTNRTGTIVELD

Specific function: Catalyzes the condensation of 6-hydroxymethyl-7,8- dihydropterin pyrophosphate (DHPP) with 4-(beta-D-ribofuranosyl)- aminobenzene-5'-phosphate (beta-RFA-P) to form 7,8-dihydropterin- 6-methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate, a precursor

COG id: COG1237

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 32673; Mature: 32673

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITTLIENTQDKDEKLKNEHGLSMFIEGNNCNVLFDTGKTGDFIENAKKLNIDLKKTDI
CEEEEEECCCCCHHHHHHCCCCCEEEEECCCEEEEEECCCCCHHHHCCHHEEEEEEECEE
LVLSHAHYDHCGGVKRLLETYDIKPKLVVSKHFFNRTDKYHYSDGSLKSDFSKEPGYAYI
EEEECCCCCHHHHHHHHHHHHCCCCEEEEEHHHCCCCCCEEECCCCCCCCCCCCCCEEEE
GTDFDKKYVEDKGIRIESLEKDVLEICDNVFVCSNFNKYYDFEKVNPNMQRKVNDEYIID
ECCCCHHHHHHCCCCHHHHHHHHHHHHCCEEEECCCCHHCCCCCCCCCHHHHCCCCEEEE
TFDEEVALGIKTKKGLVILLGCAHPGFLNMVKTIEERTNEKIVGIIGGTHLIEADDERIK
CCCCCEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCEEEECCHHHHH
KSVDYLNKSGVELLGLSHCTGEKAVEIFNKECKTSFTNRTGTIVELD
HHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MKITTLIENTQDKDEKLKNEHGLSMFIEGNNCNVLFDTGKTGDFIENAKKLNIDLKKTDI
CEEEEEECCCCCHHHHHHCCCCCEEEEECCCEEEEEECCCCCHHHHCCHHEEEEEEECEE
LVLSHAHYDHCGGVKRLLETYDIKPKLVVSKHFFNRTDKYHYSDGSLKSDFSKEPGYAYI
EEEECCCCCHHHHHHHHHHHHCCCCEEEEEHHHCCCCCCEEECCCCCCCCCCCCCCEEEE
GTDFDKKYVEDKGIRIESLEKDVLEICDNVFVCSNFNKYYDFEKVNPNMQRKVNDEYIID
ECCCCHHHHHHCCCCHHHHHHHHHHHHCCEEEECCCCHHCCCCCCCCCHHHHCCCCEEEE
TFDEEVALGIKTKKGLVILLGCAHPGFLNMVKTIEERTNEKIVGIIGGTHLIEADDERIK
CCCCCEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCEEEECCHHHHH
KSVDYLNKSGVELLGLSHCTGEKAVEIFNKECKTSFTNRTGTIVELD
HHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]