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The map label for this gene is hppA [H]

Identifier: 187935138

GI number: 187935138

Start: 3153646

End: 3155673

Strand: Reverse

Name: hppA [H]

Synonym: CLL_A3052

Alternate gene names: 187935138

Gene position: 3155673-3153646 (Counterclockwise)

Preceding gene: 187933016

Following gene: 187934548

Centisome position: 83.04

GC content: 32.94

Gene sequence:

>2028_bases
ATGAATCTATTATATGTTTCATTAATAGCTGGTTTTATTGCTCTTATTGTTGTCATTTTTTTAGCAAAGGATATATTGAA
AAAAAGCCCTGGAAATGAAAAGATGATTGAAATTTCTGGTTATATTGAAGAAGGTGCAATGGCTTTTTTAAGAAAGGAGT
ATTCTTACTTATGTGTCTTTATAGTAGTAGTTGCTATTGCTATACTAGTATTTTTAAATTATAAAACAGCAATAGCATTT
GTTGTTGGTGCACTATTTTCAATTATAGCAGGTTATATTGGTATGAGAATAGCTGTAAAATCTAATGTTAGAACAGCCGA
GGCTGCAAAATCAGGAATAAAAGAGGCACTATCAGTTGCTTTTTCTGGTGGAACAGTAATGGGATTATGTGTAGTAGGAC
TAGGTATAATTGGATTAAGTATTTTTTCAATTGTATTTGATTTAAATGTAGAGTATATAACAGGATTTGGATTAGGTGCA
TCATCTATTGCTTTATTTGCAAGAGTTGGTGGTGGAATTTATACTAAAGCAGCTGATGTTGGAGCAGATTTAGTGGGGAA
AGTTGAAGCTGGTATTCCAGAAGATGATCCAAGAAATCCAGCTGTTATAGCAGATAATGTTGGTGATAATGTTGGAGACG
TTGCAGGTATGGGAGCAGATTTATTTGAATCTTATGTTGGATCAATTATATCTGCAATAACTCTAGGCGCTGTATTGGTT
AGTTCATGGGGAAAAGAAATAGTAATTTTCCCATTAGTTTTATCTTCAATAGGTATTTTAGCATCATTAATAGGAATTGT
ATTTGTTAAATCATATAAAGGAGATAATCCTCAAAAGGCTTTAAATTTAGGTAGTACAATTTCAGGTGCAATAGTATTAG
TAGCAGGATTTATAGCTTGTAAATATTTACTTGGAAGCTATAAAATTTTCTTACCTGTAATTGCTGGATTACTAATAGGG
TTATTAATTGGTAAAATTACTGAATTCTATACTTCTGCTGATTATAAATCAGTTAAATTTATTGCAAATGAGTCAGAGAC
AGGTCCTGCAACAAATATTATAGCAGGATTATCAGTTGGAATGAGATCAACAGTTGTACCTATACTATTAATCGCTGTAG
GAATAATAGTATCATTTTTTGCAATAGGTGGAGCAAAAGATACTGCATTAGGCTTATATGGTATAGCACTATCAGCAGTG
GGCATGTTATCAACAACAGCTATAACAGTTGCTGTTGATGCATATGGACCAATAGCAGATAATGCTGGAGGAATAGCAGA
AATGTGTGATTTAGATGATAGCATCAGAGAGATAACTGATAAATTAGATTCTGTTGGTAATACAACAGCAGCAATAGGAA
AAGGATTTGCTATTGGTTCGGCAGCACTTACTGCTTTGGCACTTTTTGCATCATATTCACAAATAGTAAATTTAGAAACT
ATAAATTTACTTAATCCATTAACATTAGTTGGAGTTTTAATTGGGGGTATGTTACCATTCCTTTTTGCTGCATTAACTAT
GCAATCAGTAGGAAAAGCCGCAACTCAAATGGTTGAGGAAGTAAGAAGACAATTTAAGGAAAATGATGGGATATTAAAAG
GAACTCAAAAACCAGATTATTCAAAATGTGTTGAAATATCAACTAATGCAGCATTAAAAGAAATGATACTTCCAGGAATA
TTGGCTATAGCAGTGCCATTGTTAGTTGGAATATTATTAGGGACTGAAGCACTAGCAGGAGTAATTGGTGGTGGTGTAGT
TACAGGTGTTATGCTTGCAATTATGATGGCAAATGCTGGTGGTGCATGGGATAATGCTAAGAAATACATTGAAAGTGGAG
TACATGGTGGAAAAGGAAGTTATGCTCATAAAGCAGGGGTCGTAGGAGATACAGTTGGAGATCCATTTAAGGATACTTCA
GGACCATCTATGAATATCTTAATAAAACTTATGACAATTGTTTCAGTAGTATTTGCACCAGTAATATTAAAATACGGTGG
AATTTTGATAAATCTATTTATTAAATAA

Upstream 100 bases:

>100_bases
CTAAATAGACAAATAGAATTATTTTATTGTCATGAAATACAAAAATTATACATAAGAATAAATAATATATAAAAACCAAT
AAAATATAAGGAGGAAATAT

Downstream 100 bases:

>100_bases
ACAATTAGATTAAGCTATATTTTAGAGAGAAAGATTGCAAGTTAAATTTATTTATAAATTAATAATTTGCAGTCTTTTTT
TGTTAAAATGAAATAAATTT

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound sodium-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; Na(+)-PPase [H]

Number of amino acids: Translated: 675; Mature: 675

Protein sequence:

>675_residues
MNLLYVSLIAGFIALIVVIFLAKDILKKSPGNEKMIEISGYIEEGAMAFLRKEYSYLCVFIVVVAIAILVFLNYKTAIAF
VVGALFSIIAGYIGMRIAVKSNVRTAEAAKSGIKEALSVAFSGGTVMGLCVVGLGIIGLSIFSIVFDLNVEYITGFGLGA
SSIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVGSIISAITLGAVLV
SSWGKEIVIFPLVLSSIGILASLIGIVFVKSYKGDNPQKALNLGSTISGAIVLVAGFIACKYLLGSYKIFLPVIAGLLIG
LLIGKITEFYTSADYKSVKFIANESETGPATNIIAGLSVGMRSTVVPILLIAVGIIVSFFAIGGAKDTALGLYGIALSAV
GMLSTTAITVAVDAYGPIADNAGGIAEMCDLDDSIREITDKLDSVGNTTAAIGKGFAIGSAALTALALFASYSQIVNLET
INLLNPLTLVGVLIGGMLPFLFAALTMQSVGKAATQMVEEVRRQFKENDGILKGTQKPDYSKCVEISTNAALKEMILPGI
LAIAVPLLVGILLGTEALAGVIGGGVVTGVMLAIMMANAGGAWDNAKKYIESGVHGGKGSYAHKAGVVGDTVGDPFKDTS
GPSMNILIKLMTIVSVVFAPVILKYGGILINLFIK

Sequences:

>Translated_675_residues
MNLLYVSLIAGFIALIVVIFLAKDILKKSPGNEKMIEISGYIEEGAMAFLRKEYSYLCVFIVVVAIAILVFLNYKTAIAF
VVGALFSIIAGYIGMRIAVKSNVRTAEAAKSGIKEALSVAFSGGTVMGLCVVGLGIIGLSIFSIVFDLNVEYITGFGLGA
SSIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVGSIISAITLGAVLV
SSWGKEIVIFPLVLSSIGILASLIGIVFVKSYKGDNPQKALNLGSTISGAIVLVAGFIACKYLLGSYKIFLPVIAGLLIG
LLIGKITEFYTSADYKSVKFIANESETGPATNIIAGLSVGMRSTVVPILLIAVGIIVSFFAIGGAKDTALGLYGIALSAV
GMLSTTAITVAVDAYGPIADNAGGIAEMCDLDDSIREITDKLDSVGNTTAAIGKGFAIGSAALTALALFASYSQIVNLET
INLLNPLTLVGVLIGGMLPFLFAALTMQSVGKAATQMVEEVRRQFKENDGILKGTQKPDYSKCVEISTNAALKEMILPGI
LAIAVPLLVGILLGTEALAGVIGGGVVTGVMLAIMMANAGGAWDNAKKYIESGVHGGKGSYAHKAGVVGDTVGDPFKDTS
GPSMNILIKLMTIVSVVFAPVILKYGGILINLFIK
>Mature_675_residues
MNLLYVSLIAGFIALIVVIFLAKDILKKSPGNEKMIEISGYIEEGAMAFLRKEYSYLCVFIVVVAIAILVFLNYKTAIAF
VVGALFSIIAGYIGMRIAVKSNVRTAEAAKSGIKEALSVAFSGGTVMGLCVVGLGIIGLSIFSIVFDLNVEYITGFGLGA
SSIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVGSIISAITLGAVLV
SSWGKEIVIFPLVLSSIGILASLIGIVFVKSYKGDNPQKALNLGSTISGAIVLVAGFIACKYLLGSYKIFLPVIAGLLIG
LLIGKITEFYTSADYKSVKFIANESETGPATNIIAGLSVGMRSTVVPILLIAVGIIVSFFAIGGAKDTALGLYGIALSAV
GMLSTTAITVAVDAYGPIADNAGGIAEMCDLDDSIREITDKLDSVGNTTAAIGKGFAIGSAALTALALFASYSQIVNLET
INLLNPLTLVGVLIGGMLPFLFAALTMQSVGKAATQMVEEVRRQFKENDGILKGTQKPDYSKCVEISTNAALKEMILPGI
LAIAVPLLVGILLGTEALAGVIGGGVVTGVMLAIMMANAGGAWDNAKKYIESGVHGGKGSYAHKAGVVGDTVGDPFKDTS
GPSMNILIKLMTIVSVVFAPVILKYGGILINLFIK

Specific function: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane [H]

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004131 [H]

Pfam domain/function: PF03030 H_PPase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 69725; Mature: 69725

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLYVSLIAGFIALIVVIFLAKDILKKSPGNEKMIEISGYIEEGAMAFLRKEYSYLCVF
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHH
IVVVAIAILVFLNYKTAIAFVVGALFSIIAGYIGMRIAVKSNVRTAEAAKSGIKEALSVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHH
FSGGTVMGLCVVGLGIIGLSIFSIVFDLNVEYITGFGLGASSIALFARVGGGIYTKAADV
HCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHHCCCCEEHHHHH
GADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVGSIISAITLGAVLV
CHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
SSWGKEIVIFPLVLSSIGILASLIGIVFVKSYKGDNPQKALNLGSTISGAIVLVAGFIAC
HCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHH
KYLLGSYKIFLPVIAGLLIGLLIGKITEFYTSADYKSVKFIANESETGPATNIIAGLSVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHH
MRSTVVPILLIAVGIIVSFFAIGGAKDTALGLYGIALSAVGMLSTTAITVAVDAYGPIAD
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCC
NAGGIAEMCDLDDSIREITDKLDSVGNTTAAIGKGFAIGSAALTALALFASYSQIVNLET
CCCCHHHHHCCCHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHH
INLLNPLTLVGVLIGGMLPFLFAALTMQSVGKAATQMVEEVRRQFKENDGILKGTQKPDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCH
SKCVEISTNAALKEMILPGILAIAVPLLVGILLGTEALAGVIGGGVVTGVMLAIMMANAG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GAWDNAKKYIESGVHGGKGSYAHKAGVVGDTVGDPFKDTSGPSMNILIKLMTIVSVVFAP
CCCHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VILKYGGILINLFIK
HHHHHCCCCEEEEEC
>Mature Secondary Structure
MNLLYVSLIAGFIALIVVIFLAKDILKKSPGNEKMIEISGYIEEGAMAFLRKEYSYLCVF
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHH
IVVVAIAILVFLNYKTAIAFVVGALFSIIAGYIGMRIAVKSNVRTAEAAKSGIKEALSVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHH
FSGGTVMGLCVVGLGIIGLSIFSIVFDLNVEYITGFGLGASSIALFARVGGGIYTKAADV
HCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHHCCCCEEHHHHH
GADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVGSIISAITLGAVLV
CHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
SSWGKEIVIFPLVLSSIGILASLIGIVFVKSYKGDNPQKALNLGSTISGAIVLVAGFIAC
HCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHH
KYLLGSYKIFLPVIAGLLIGLLIGKITEFYTSADYKSVKFIANESETGPATNIIAGLSVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHH
MRSTVVPILLIAVGIIVSFFAIGGAKDTALGLYGIALSAVGMLSTTAITVAVDAYGPIAD
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCC
NAGGIAEMCDLDDSIREITDKLDSVGNTTAAIGKGFAIGSAALTALALFASYSQIVNLET
CCCCHHHHHCCCHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHH
INLLNPLTLVGVLIGGMLPFLFAALTMQSVGKAATQMVEEVRRQFKENDGILKGTQKPDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCH
SKCVEISTNAALKEMILPGILAIAVPLLVGILLGTEALAGVIGGGVVTGVMLAIMMANAG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GAWDNAKKYIESGVHGGKGSYAHKAGVVGDTVGDPFKDTSGPSMNILIKLMTIVSVVFAP
CCCHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VILKYGGILINLFIK
HHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]