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The map label for this gene is xseA [H]

Identifier: 187934773

GI number: 187934773

Start: 2495514

End: 2496713

Strand: Reverse

Name: xseA [H]

Synonym: CLL_A2404

Alternate gene names: 187934773

Gene position: 2496713-2495514 (Counterclockwise)

Preceding gene: 187935746

Following gene: 187933296

Centisome position: 65.7

GC content: 25.92

Gene sequence:

>1200_bases
ATGAAGATTAAAACTTTAACTGTTTCAGATCTAACAAACTATATAAAAAAAGTAATTGATAATGACTTTATTTTAAATAA
TCTCTCTGTAAAAGGGGAGATTTCTAATTTAAAATTCCATAGCAGTGGACATATTTATTTTTCTTTAAAAGATAACAATA
GTAAAGTAAATTGCGTTATGTTTAAAAGCAAAGCAAGTCTTTTAAATATTGCTTTAGAAGATGGTATGGAAGTTATGGTA
AAGGGAAGAGCATCTATTTACACAGCTACAGGGAGTTTTCAACTTTATTGTGATGAGATAAAAAAAGAAGGGCAAGGAGA
GTTATTTATAAAATTCGAAGCTCTTAAAGAAAAATTATCAAAGTCTGGATATTTTGATGAAAAGTATAAAAAGAATATCC
CTATGTACGCTAAAAGAATAGGTATTGTAACCTCATCAACAGGTGCAGTAATAAGAGATATAATAAATGTAACTAAAAGA
AGAAACTCATTAGTAGACATAATATTATATCCAGCTAAGGTTCAAGGCGATAATGCATATAAAGAAATAATTGCAGGAAT
TGAATATTTTAATAAGAAGAAAAATATAGATATAATAATAGTTGGAAGAGGTGGAGGTTCTATAGAAGAATTATGGAACT
TTAATGAAGAAGAGCTTGCAAAAGTTATATTTAATTCTAAGTTGCCTATTATTTCAGCAGTAGGTCATGAAGTCGATTTT
ACAATTTCAGATTTTGTTTCTGATGTAAGAGCAGCAACACCATCACAAGCAGCTGAAATAGCAGTTCCGCTATTAAGTGA
TATAAACACAAGAATTTATGAAATATCAAAATCATTAGATTATGAAATACAAAAGAAATTAAAAGATTGCAAAAGTAGAT
TAGAGTCAAATGAGAGAATTTTAAAATTACATTCTCCAATATCAAAAATAGTAAACTCATATTTAGAAATTGATAAATTA
AAAGATAGATTATATTTTGCAATAGATATAAAAATAAAAAGAGAAAAGCAAAAGATAGAATCATTAAATAATTTATTAAG
CGCTAATAATCCTATAAAGGTACTTAATAAAGGATATGCTATAATAGAGGATGAAAATAATAATATCATTAAAGAAATAT
CGCAATTAAACGAAGAAAAAGAAATAAGTGTTTCTTTAAGTGATGGAAATATTAAAGGGAATTTTATACCTATTAAGTAA

Upstream 100 bases:

>100_bases
GTAATAGATAAAGCTTCTTTCGTAACACCAGTACCAGGTGGAGTTGGAGCTTTAACTACTACTCTTTTAATAAAAAATTC
ATGTGAGGCTTTAAAGGAAT

Downstream 100 bases:

>100_bases
GGAGAGTATTATATGGCAAAGAAAGAAAGCTATGAAGATATGCTTGGTAAGCTTCAAGATATTTTAAGTACTTTAGAAGA
TGACAATTTAAACCTTGAAG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MKIKTLTVSDLTNYIKKVIDNDFILNNLSVKGEISNLKFHSSGHIYFSLKDNNSKVNCVMFKSKASLLNIALEDGMEVMV
KGRASIYTATGSFQLYCDEIKKEGQGELFIKFEALKEKLSKSGYFDEKYKKNIPMYAKRIGIVTSSTGAVIRDIINVTKR
RNSLVDIILYPAKVQGDNAYKEIIAGIEYFNKKKNIDIIIVGRGGGSIEELWNFNEEELAKVIFNSKLPIISAVGHEVDF
TISDFVSDVRAATPSQAAEIAVPLLSDINTRIYEISKSLDYEIQKKLKDCKSRLESNERILKLHSPISKIVNSYLEIDKL
KDRLYFAIDIKIKREKQKIESLNNLLSANNPIKVLNKGYAIIEDENNNIIKEISQLNEEKEISVSLSDGNIKGNFIPIK

Sequences:

>Translated_399_residues
MKIKTLTVSDLTNYIKKVIDNDFILNNLSVKGEISNLKFHSSGHIYFSLKDNNSKVNCVMFKSKASLLNIALEDGMEVMV
KGRASIYTATGSFQLYCDEIKKEGQGELFIKFEALKEKLSKSGYFDEKYKKNIPMYAKRIGIVTSSTGAVIRDIINVTKR
RNSLVDIILYPAKVQGDNAYKEIIAGIEYFNKKKNIDIIIVGRGGGSIEELWNFNEEELAKVIFNSKLPIISAVGHEVDF
TISDFVSDVRAATPSQAAEIAVPLLSDINTRIYEISKSLDYEIQKKLKDCKSRLESNERILKLHSPISKIVNSYLEIDKL
KDRLYFAIDIKIKREKQKIESLNNLLSANNPIKVLNKGYAIIEDENNNIIKEISQLNEEKEISVSLSDGNIKGNFIPIK
>Mature_399_residues
MKIKTLTVSDLTNYIKKVIDNDFILNNLSVKGEISNLKFHSSGHIYFSLKDNNSKVNCVMFKSKASLLNIALEDGMEVMV
KGRASIYTATGSFQLYCDEIKKEGQGELFIKFEALKEKLSKSGYFDEKYKKNIPMYAKRIGIVTSSTGAVIRDIINVTKR
RNSLVDIILYPAKVQGDNAYKEIIAGIEYFNKKKNIDIIIVGRGGGSIEELWNFNEEELAKVIFNSKLPIISAVGHEVDF
TISDFVSDVRAATPSQAAEIAVPLLSDINTRIYEISKSLDYEIQKKLKDCKSRLESNERILKLHSPISKIVNSYLEIDKL
KDRLYFAIDIKIKREKQKIESLNNLLSANNPIKVLNKGYAIIEDENNNIIKEISQLNEEKEISVSLSDGNIKGNFIPIK

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=446, Percent_Identity=32.0627802690583, Blast_Score=281, Evalue=6e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 45096; Mature: 45096

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKTLTVSDLTNYIKKVIDNDFILNNLSVKGEISNLKFHSSGHIYFSLKDNNSKVNCVM
CEEEEEEHHHHHHHHHHHHCCCEEEECEEEEEEECCEEEECCCEEEEEEECCCCEEEEEE
FKSKASLLNIALEDGMEVMVKGRASIYTATGSFQLYCDEIKKEGQGELFIKFEALKEKLS
EECCCHHEEHHHHCCCEEEEECCEEEEEECCCEEEEEHHHCCCCCCCEEEEEHHHHHHHH
KSGYFDEKYKKNIPMYAKRIGIVTSSTGAVIRDIINVTKRRNSLVDIILYPAKVQGDNAY
HCCCCCHHHHCCCCHHHHHEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEECEECCCHHH
KEIIAGIEYFNKKKNIDIIIVGRGGGSIEELWNFNEEELAKVIFNSKLPIISAVGHEVDF
HHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHCCCCCEEEECCCCCCE
TISDFVSDVRAATPSQAAEIAVPLLSDINTRIYEISKSLDYEIQKKLKDCKSRLESNERI
EHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEE
LKLHSPISKIVNSYLEIDKLKDRLYFAIDIKIKREKQKIESLNNLLSANNPIKVLNKGYA
EEHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEHHHHHHHHHHHHHCCCCCEEEECCCEE
IIEDENNNIIKEISQLNEEKEISVSLSDGNIKGNFIPIK
EEECCCCHHHHHHHHCCCCCEEEEEEECCCEECCEEECC
>Mature Secondary Structure
MKIKTLTVSDLTNYIKKVIDNDFILNNLSVKGEISNLKFHSSGHIYFSLKDNNSKVNCVM
CEEEEEEHHHHHHHHHHHHCCCEEEECEEEEEEECCEEEECCCEEEEEEECCCCEEEEEE
FKSKASLLNIALEDGMEVMVKGRASIYTATGSFQLYCDEIKKEGQGELFIKFEALKEKLS
EECCCHHEEHHHHCCCEEEEECCEEEEEECCCEEEEEHHHCCCCCCCEEEEEHHHHHHHH
KSGYFDEKYKKNIPMYAKRIGIVTSSTGAVIRDIINVTKRRNSLVDIILYPAKVQGDNAY
HCCCCCHHHHCCCCHHHHHEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEECEECCCHHH
KEIIAGIEYFNKKKNIDIIIVGRGGGSIEELWNFNEEELAKVIFNSKLPIISAVGHEVDF
HHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHCCCCCEEEECCCCCCE
TISDFVSDVRAATPSQAAEIAVPLLSDINTRIYEISKSLDYEIQKKLKDCKSRLESNERI
EHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEE
LKLHSPISKIVNSYLEIDKLKDRLYFAIDIKIKREKQKIESLNNLLSANNPIKVLNKGYA
EEHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEHHHHHHHHHHHHHCCCCCEEEECCCEE
IIEDENNNIIKEISQLNEEKEISVSLSDGNIKGNFIPIK
EEECCCCHHHHHHHHCCCCCEEEEEEECCCEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA