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The map label for this gene is rnz [H]

Identifier: 187934145

GI number: 187934145

Start: 1084378

End: 1085325

Strand: Reverse

Name: rnz [H]

Synonym: CLL_A1059

Alternate gene names: 187934145

Gene position: 1085325-1084378 (Counterclockwise)

Preceding gene: 187934635

Following gene: 187935756

Centisome position: 28.56

GC content: 27.64

Gene sequence:

>948_bases
ATGATTGATTTATGTGTTTTAGGAACAACAGGTGGAATGCCTATGGTTGATAAGTACTTATCTGCTACTTTGATAAACAT
AAATGGTAGGAAAATTTTGATTGATTGTGGTGAAGGTACACAAGTTGCTATGAGAAAAATAGGTTGGGGATTTAAATCAG
TAGATTTAATTTGTATAACACACTCACATGGAGATCACACAATAGGACTACCTGGATTAATCTCTATAATGGGTAATTCT
GGTAGAACTGAAAAGGTTACAGTAGTTGGACCAAAAGGAATAAAAGAAATTGTTAATGGACTAAATGTTATAAATCCTTA
TCTTCCTTATGAATTAGAAATTATTGAATTAGAGAATAATGATTTAAAATTTATAATAGATAAAAATAATATGTCTTTAT
GTGAAGATAATAATAAATGTAACCTTATATTGTCTTCATTAGAAGTTGAACATTCTGCTAAATGTTTAAGTTATAGTTTT
TATATAAAAAGACGCCCTAGATTTTCAGTAGAAAAAGCATCTAAAAATAATGTTCCTAAACCTTTATGGAGTAAACTACA
AAATCAAGAAATTATAAATTATGATAATAAAATATATACTCCTGATTTAGTACTTGATAATGCTCGTAAAGGTATTAAAA
TATCATATGTAACTGATACTAGACCAATTAGTGCTATTCCTGAATTTATAAAATACAGTGACTTGTTTATTTGTGAAGGA
ACTTATGGTAGCGATGAGGATATAGACAAAGCTATAAAAAACAAACATATGACATTTAGAGAAAGTGCTACATTAGCACT
AAATGGAGAATGTAAAGAATTAATTTTAACTCATTTTAGTCCTGCACTATCTGAACCTGAAAGTTTTGTAGATAATGCAA
AACAAGTTTTTCATAATTCTAGCGTTGCTTATGATGGTCTAATTAAAACCTTAAAATTTATAGATTAG

Upstream 100 bases:

>100_bases
TTATCAATTGTACAAAATAAAAGTAGAATTTTTTATATTTTTTTTGTTATTATAATATATAGGTAATTTTTTACCATATA
TAAAGATAGGAGAGCTTTTT

Downstream 100 bases:

>100_bases
TTTACATGAAATACTTAACAAATTCCAGAATTTATTTTTAATTTTACTTTTACTTTATTAAAAGATATAATATGTAAATG
TAAAAACATAATTACTTTTT

Product: ribonuclease Z

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MIDLCVLGTTGGMPMVDKYLSATLININGRKILIDCGEGTQVAMRKIGWGFKSVDLICITHSHGDHTIGLPGLISIMGNS
GRTEKVTVVGPKGIKEIVNGLNVINPYLPYELEIIELENNDLKFIIDKNNMSLCEDNNKCNLILSSLEVEHSAKCLSYSF
YIKRRPRFSVEKASKNNVPKPLWSKLQNQEIINYDNKIYTPDLVLDNARKGIKISYVTDTRPISAIPEFIKYSDLFICEG
TYGSDEDIDKAIKNKHMTFRESATLALNGECKELILTHFSPALSEPESFVDNAKQVFHNSSVAYDGLIKTLKFID

Sequences:

>Translated_315_residues
MIDLCVLGTTGGMPMVDKYLSATLININGRKILIDCGEGTQVAMRKIGWGFKSVDLICITHSHGDHTIGLPGLISIMGNS
GRTEKVTVVGPKGIKEIVNGLNVINPYLPYELEIIELENNDLKFIIDKNNMSLCEDNNKCNLILSSLEVEHSAKCLSYSF
YIKRRPRFSVEKASKNNVPKPLWSKLQNQEIINYDNKIYTPDLVLDNARKGIKISYVTDTRPISAIPEFIKYSDLFICEG
TYGSDEDIDKAIKNKHMTFRESATLALNGECKELILTHFSPALSEPESFVDNAKQVFHNSSVAYDGLIKTLKFID
>Mature_315_residues
MIDLCVLGTTGGMPMVDKYLSATLININGRKILIDCGEGTQVAMRKIGWGFKSVDLICITHSHGDHTIGLPGLISIMGNS
GRTEKVTVVGPKGIKEIVNGLNVINPYLPYELEIIELENNDLKFIIDKNNMSLCEDNNKCNLILSSLEVEHSAKCLSYSF
YIKRRPRFSVEKASKNNVPKPLWSKLQNQEIINYDNKIYTPDLVLDNARKGIKISYVTDTRPISAIPEFIKYSDLFICEG
TYGSDEDIDKAIKNKHMTFRESATLALNGECKELILTHFSPALSEPESFVDNAKQVFHNSSVAYDGLIKTLKFID

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

Organism=Escherichia coli, GI87082078, Length=315, Percent_Identity=27.6190476190476, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR013471 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 35229; Mature: 35229

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLCVLGTTGGMPMVDKYLSATLININGRKILIDCGEGTQVAMRKIGWGFKSVDLICIT
CEEEEEEECCCCCHHHHHHHEEEEEEECCCEEEEECCCCHHHHHHHHCCCCCCEEEEEEE
HSHGDHTIGLPGLISIMGNSGRTEKVTVVGPKGIKEIVNGLNVINPYLPYELEIIELENN
ECCCCCEECCCHHEEEECCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCEEEEEEECCC
DLKFIIDKNNMSLCEDNNKCNLILSSLEVEHSAKCLSYSFYIKRRPRFSVEKASKNNVPK
CEEEEEECCCCEEECCCCCEEEEEEEECCHHCHHEEEEEEEEEECCCCCEECCCCCCCCC
PLWSKLQNQEIINYDNKIYTPDLVLDNARKGIKISYVTDTRPISAIPEFIKYSDLFICEG
HHHHHHCCCEEECCCCEEECCCEEECCCCCCEEEEEEECCCCHHHHHHHHCCCCEEEEEC
TYGSDEDIDKAIKNKHMTFRESATLALNGECKELILTHFSPALSEPESFVDNAKQVFHNS
CCCCCHHHHHHHHHCCCEEECCEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCC
SVAYDGLIKTLKFID
CCCHHHHHHHHHHCC
>Mature Secondary Structure
MIDLCVLGTTGGMPMVDKYLSATLININGRKILIDCGEGTQVAMRKIGWGFKSVDLICIT
CEEEEEEECCCCCHHHHHHHEEEEEEECCCEEEEECCCCHHHHHHHHCCCCCCEEEEEEE
HSHGDHTIGLPGLISIMGNSGRTEKVTVVGPKGIKEIVNGLNVINPYLPYELEIIELENN
ECCCCCEECCCHHEEEECCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCEEEEEEECCC
DLKFIIDKNNMSLCEDNNKCNLILSSLEVEHSAKCLSYSFYIKRRPRFSVEKASKNNVPK
CEEEEEECCCCEEECCCCCEEEEEEEECCHHCHHEEEEEEEEEECCCCCEECCCCCCCCC
PLWSKLQNQEIINYDNKIYTPDLVLDNARKGIKISYVTDTRPISAIPEFIKYSDLFICEG
HHHHHHCCCEEECCCCEEECCCEEECCCCCCEEEEEEECCCCHHHHHHHHCCCCEEEEEC
TYGSDEDIDKAIKNKHMTFRESATLALNGECKELILTHFSPALSEPESFVDNAKQVFHNS
CCCCCHHHHHHHHHCCCEEECCEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCC
SVAYDGLIKTLKFID
CCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA