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The map label for this gene is yxdK [H]

Identifier: 187932997

GI number: 187932997

Start: 3724587

End: 3725603

Strand: Reverse

Name: yxdK [H]

Synonym: CLL_A3517

Alternate gene names: 187932997

Gene position: 3725603-3724587 (Counterclockwise)

Preceding gene: 187933755

Following gene: 187934099

Centisome position: 98.03

GC content: 23.3

Gene sequence:

>1017_bases
ATGAGTATATTAGGGTATTTAAAAGATAGGCTACTTTATTTAATAATAAATTTCATATTATTTATAAGTATAGTTAGTGT
TATGCTTATGTTAAAAATTCCGTTAGTAATAATTTTTATAACATTCTTAATGTGGTTTGTGCCAATAAGTATATATTTTG
TTTTAGAAATTATTAAATATAAAAAGTTTTATGATAATTTAAATGGAGTAATGGAAAAGTTAGATAGAAAATATTTATTA
TCAGAACTTATTGATGAGCCAAATTTTATTGAGGGCAAAATTCTTTATAATATATTAAAAGAAACTAATAGAGATATGAA
TGAGGAAATAAAAAAATATAAAAATGCTCAAATAGATTATAGGGAATATATAGAAACTTGGGTACATGAAATAAAAACAC
CGATAGCATCATCTATGTTAGTTATAGATAATAACTTAAATGAAACTACCAATAAAATAAAATATCAAATTAAGAGAGTA
GAGGAATTTGTAGAGCAAGTATTATATTATTCAAAGATAGGTGAAGTAAGCAAGGATTACATAGTTAAAGAATTTAAGAT
AAAAACGGTAATTAATAAGGTTATAAAAAATAATTCTAGAGATTTTATAACTAAAAAGATATCCTTAGAAATGAATGATT
TAGAGCAAAATATATATAGTGATGAAAAATGGATTTATTTTATACTTAATCAGATAATAGGAAATTCATTAAAGTACTCT
AAAGATAATGATTCAAAGATAAAAATTTATTCATTGAAGAATAATCATAATGTAACTTTGGTTGTTGAAGATAATGGTGT
TGGAATAAATAATCAAGATACAGATAAGGTTTTTGAGAAAGGCTTTACTGGAGAAAACGGAAGGATATATGGAAGGTCTA
CAGGAATGGGACTTTATATTTGTAAAAAGCTTTCAGAAAAACTAGGGATATCTATAAGTATTAATTCTTTAAAAGGCCAA
GGAACTAAAGTAAATATCATTTTCCCAATAGGAAAGTTAACTGATTATGTAAAGTAA

Upstream 100 bases:

>100_bases
ATACTCTTTCTGTAAATATAACAAGGCTAAGAAGAAAGCTTGAGGATATAGGAATAAAAGATGCAATAGAGACTAGAAGA
GGATTAGGATATATAATGCC

Downstream 100 bases:

>100_bases
ACATTGGTATATAGCTTATTTTGAATTAAAAAGAAAACACAAGGACTTACACATTTAATAGATAGTCTTTATAAGTGCAA
TATAAAATATTAAGAATATA

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MSILGYLKDRLLYLIINFILFISIVSVMLMLKIPLVIIFITFLMWFVPISIYFVLEIIKYKKFYDNLNGVMEKLDRKYLL
SELIDEPNFIEGKILYNILKETNRDMNEEIKKYKNAQIDYREYIETWVHEIKTPIASSMLVIDNNLNETTNKIKYQIKRV
EEFVEQVLYYSKIGEVSKDYIVKEFKIKTVINKVIKNNSRDFITKKISLEMNDLEQNIYSDEKWIYFILNQIIGNSLKYS
KDNDSKIKIYSLKNNHNVTLVVEDNGVGINNQDTDKVFEKGFTGENGRIYGRSTGMGLYICKKLSEKLGISISINSLKGQ
GTKVNIIFPIGKLTDYVK

Sequences:

>Translated_338_residues
MSILGYLKDRLLYLIINFILFISIVSVMLMLKIPLVIIFITFLMWFVPISIYFVLEIIKYKKFYDNLNGVMEKLDRKYLL
SELIDEPNFIEGKILYNILKETNRDMNEEIKKYKNAQIDYREYIETWVHEIKTPIASSMLVIDNNLNETTNKIKYQIKRV
EEFVEQVLYYSKIGEVSKDYIVKEFKIKTVINKVIKNNSRDFITKKISLEMNDLEQNIYSDEKWIYFILNQIIGNSLKYS
KDNDSKIKIYSLKNNHNVTLVVEDNGVGINNQDTDKVFEKGFTGENGRIYGRSTGMGLYICKKLSEKLGISISINSLKGQ
GTKVNIIFPIGKLTDYVK
>Mature_337_residues
SILGYLKDRLLYLIINFILFISIVSVMLMLKIPLVIIFITFLMWFVPISIYFVLEIIKYKKFYDNLNGVMEKLDRKYLLS
ELIDEPNFIEGKILYNILKETNRDMNEEIKKYKNAQIDYREYIETWVHEIKTPIASSMLVIDNNLNETTNKIKYQIKRVE
EFVEQVLYYSKIGEVSKDYIVKEFKIKTVINKVIKNNSRDFITKKISLEMNDLEQNIYSDEKWIYFILNQIIGNSLKYSK
DNDSKIKIYSLKNNHNVTLVVEDNGVGINNQDTDKVFEKGFTGENGRIYGRSTGMGLYICKKLSEKLGISISINSLKGQG
TKVNIIFPIGKLTDYVK

Specific function: Probable member of the two-component regulatory system yxdK/yxdJ. May activate yxdJ in response to the antibacterial protein LL-37 [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=229, Percent_Identity=24.0174672489083, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39596; Mature: 39465

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILGYLKDRLLYLIINFILFISIVSVMLMLKIPLVIIFITFLMWFVPISIYFVLEIIKY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKFYDNLNGVMEKLDRKYLLSELIDEPNFIEGKILYNILKETNRDMNEEIKKYKNAQIDY
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCH
REYIETWVHEIKTPIASSMLVIDNNLNETTNKIKYQIKRVEEFVEQVLYYSKIGEVSKDY
HHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
IVKEFKIKTVINKVIKNNSRDFITKKISLEMNDLEQNIYSDEKWIYFILNQIIGNSLKYS
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
KDNDSKIKIYSLKNNHNVTLVVEDNGVGINNQDTDKVFEKGFTGENGRIYGRSTGMGLYI
CCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCHHHHHHCCCCCCCCEEEECCCCCHHHH
CKKLSEKLGISISINSLKGQGTKVNIIFPIGKLTDYVK
HHHHHHHCCEEEEEECCCCCCCEEEEEEECHHHHHCCC
>Mature Secondary Structure 
SILGYLKDRLLYLIINFILFISIVSVMLMLKIPLVIIFITFLMWFVPISIYFVLEIIKY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKFYDNLNGVMEKLDRKYLLSELIDEPNFIEGKILYNILKETNRDMNEEIKKYKNAQIDY
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCH
REYIETWVHEIKTPIASSMLVIDNNLNETTNKIKYQIKRVEEFVEQVLYYSKIGEVSKDY
HHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
IVKEFKIKTVINKVIKNNSRDFITKKISLEMNDLEQNIYSDEKWIYFILNQIIGNSLKYS
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
KDNDSKIKIYSLKNNHNVTLVVEDNGVGINNQDTDKVFEKGFTGENGRIYGRSTGMGLYI
CCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCHHHHHHCCCCCCCCEEEECCCCCHHHH
CKKLSEKLGISISINSLKGQGTKVNIIFPIGKLTDYVK
HHHHHHHCCEEEEEECCCCCCCEEEEEEECHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7952181; 9384377; 8867804 [H]