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The map label for this gene is pqqL [C]

Identifier: 187932459

GI number: 187932459

Start: 3070950

End: 3072155

Strand: Reverse

Name: pqqL [C]

Synonym: CLL_A2983

Alternate gene names: 187932459

Gene position: 3072155-3070950 (Counterclockwise)

Preceding gene: 187934852

Following gene: 187933413

Centisome position: 80.84

GC content: 23.55

Gene sequence:

>1206_bases
TTGCAAGAATATATTTTTGAAAATAAATTAAAGTTAATATATAAAAAAAGTGAATCGGAATTAGCATCTATATGTATATC
TTTAGAGGCAGGGGCAGGAGTAGAGAAAGATATTTTTGGAATAGCACATGCTACTGAACATATGATATTTAAAAATACTA
AAAATAGAAATGAAGCACAAATAAATAAAGAGTTAAGTTCTATATTTGGATTCCATAATGCAATGACAAATTATCCATAT
GTAATATACTATGGAACTTTACTTAGTAATGAACTTGAAAAGGGTCTAGAAATTTTTTCGGATATAATTATAAATACAGA
ATTTAAAGAAGATGGATTTAAAGAAGAAATTAATGTAATAATAGAAGAACTTAATGAATGGGATGAAGAAGTTGAACAAT
ATTGTGAGGATAAACTGTTTTTTAATTCATTTCAAAATAGAAGAATAAAATACCCCATAATAGGTCTTGAAGATCAACTT
GAATCAATAAAATTAGAAGATATTAAGAAGTTTTATGAAGAATATTATTTTCCGGGAAATACGTCTATTGCTGTAATATC
TTCACTAGATTTTGAAGAAGTAAAGAACTTAGTAGAAAAATATTTCAGATTATGGGAAAAGAAAATTAAGATAATAGAAG
AAGTTTGTTATGAAAATAATATTTCAGACACATTCTTAGATAAAAGAGATGGGATAAAGACATGTAAGGTTCAAATGATT
TTTAATATACATGAACTAAATGATAATGAGATTAGTTTATTAAGAATATTTGATGAGTATTTTGGACAAGGTGTAAATTC
ATTACTTTTTGATACATTAAGAACTAAAAATGGTCTTATTTATGATGTTATTACTAATATAGCTCATGAAAAATACATAA
AACTCTATAAAATTACATTTAGTACATCAAAAGAAAATGTAGATAAATCTATAGAATTAATAAAACAATGTATCAATAAA
CTTGCTGAATTAAAAAATAGCATTGATATGGAGGATATAAAACAACTAATAAAGTCTTATAAACTTAAAAAATTGTTTAA
AGAAGAAAAGAGTATTGTACTAGCAAAAGAAATTTCAACTTACGATACTATGTTTGGAGATTACACAGTATACACAAATG
AAAATTTAAATAATTTAACTAAAGAAGATATATTTGATGTAGGAATAAAAACATTAGAAAATCCATCTATAGAAATTATA
TCTTAA

Upstream 100 bases:

>100_bases
ATAATGATATAATAAATCATTATAACATTATAAACTTTATTAATTTAGTATTATTAAAATATATACTGAATTTAAAAGAA
TACTTTAAGGGGGAAGATTT

Downstream 100 bases:

>100_bases
AGATAATATTTACTAACATTATTATATTTTAAGAAAAGTTAAGAGTGTAATATAAGGGCGTAGTGGCATTGAAATTTGTT
TTTTAGAACTCTTAATGAAT

Product: zinc protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MQEYIFENKLKLIYKKSESELASICISLEAGAGVEKDIFGIAHATEHMIFKNTKNRNEAQINKELSSIFGFHNAMTNYPY
VIYYGTLLSNELEKGLEIFSDIIINTEFKEDGFKEEINVIIEELNEWDEEVEQYCEDKLFFNSFQNRRIKYPIIGLEDQL
ESIKLEDIKKFYEEYYFPGNTSIAVISSLDFEEVKNLVEKYFRLWEKKIKIIEEVCYENNISDTFLDKRDGIKTCKVQMI
FNIHELNDNEISLLRIFDEYFGQGVNSLLFDTLRTKNGLIYDVITNIAHEKYIKLYKITFSTSKENVDKSIELIKQCINK
LAELKNSIDMEDIKQLIKSYKLKKLFKEEKSIVLAKEISTYDTMFGDYTVYTNENLNNLTKEDIFDVGIKTLENPSIEII
S

Sequences:

>Translated_401_residues
MQEYIFENKLKLIYKKSESELASICISLEAGAGVEKDIFGIAHATEHMIFKNTKNRNEAQINKELSSIFGFHNAMTNYPY
VIYYGTLLSNELEKGLEIFSDIIINTEFKEDGFKEEINVIIEELNEWDEEVEQYCEDKLFFNSFQNRRIKYPIIGLEDQL
ESIKLEDIKKFYEEYYFPGNTSIAVISSLDFEEVKNLVEKYFRLWEKKIKIIEEVCYENNISDTFLDKRDGIKTCKVQMI
FNIHELNDNEISLLRIFDEYFGQGVNSLLFDTLRTKNGLIYDVITNIAHEKYIKLYKITFSTSKENVDKSIELIKQCINK
LAELKNSIDMEDIKQLIKSYKLKKLFKEEKSIVLAKEISTYDTMFGDYTVYTNENLNNLTKEDIFDVGIKTLENPSIEII
S
>Mature_401_residues
MQEYIFENKLKLIYKKSESELASICISLEAGAGVEKDIFGIAHATEHMIFKNTKNRNEAQINKELSSIFGFHNAMTNYPY
VIYYGTLLSNELEKGLEIFSDIIINTEFKEDGFKEEINVIIEELNEWDEEVEQYCEDKLFFNSFQNRRIKYPIIGLEDQL
ESIKLEDIKKFYEEYYFPGNTSIAVISSLDFEEVKNLVEKYFRLWEKKIKIIEEVCYENNISDTFLDKRDGIKTCKVQMI
FNIHELNDNEISLLRIFDEYFGQGVNSLLFDTLRTKNGLIYDVITNIAHEKYIKLYKITFSTSKENVDKSIELIKQCINK
LAELKNSIDMEDIKQLIKSYKLKKLFKEEKSIVLAKEISTYDTMFGDYTVYTNENLNNLTKEDIFDVGIKTLENPSIEII
S

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=198, Percent_Identity=25.7575757575758, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI46593007, Length=202, Percent_Identity=22.2772277227723, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71999683, Length=198, Percent_Identity=25.2525252525253, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17553678, Length=198, Percent_Identity=22.2222222222222, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323192, Length=182, Percent_Identity=28.021978021978, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357875, Length=194, Percent_Identity=24.7422680412371, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24646943, Length=194, Percent_Identity=24.7422680412371, Blast_Score=85, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 47077; Mature: 47077

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEYIFENKLKLIYKKSESELASICISLEAGAGVEKDIFGIAHATEHMIFKNTKNRNEAQ
CCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
INKELSSIFGFHNAMTNYPYVIYYGTLLSNELEKGLEIFSDIIINTEFKEDGFKEEINVI
HHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
IEELNEWDEEVEQYCEDKLFFNSFQNRRIKYPIIGLEDQLESIKLEDIKKFYEEYYFPGN
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCEECCHHHHHHCCHHHHHHHHHHHCCCCC
TSIAVISSLDFEEVKNLVEKYFRLWEKKIKIIEEVCYENNISDTFLDKRDGIKTCKVQMI
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCEEEEEEE
FNIHELNDNEISLLRIFDEYFGQGVNSLLFDTLRTKNGLIYDVITNIAHEKYIKLYKITF
EEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEEEEE
STSKENVDKSIELIKQCINKLAELKNSIDMEDIKQLIKSYKLKKLFKEEKSIVLAKEIST
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCEEEHHHHHH
YDTMFGDYTVYTNENLNNLTKEDIFDVGIKTLENPSIEIIS
HHHHCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEC
>Mature Secondary Structure
MQEYIFENKLKLIYKKSESELASICISLEAGAGVEKDIFGIAHATEHMIFKNTKNRNEAQ
CCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
INKELSSIFGFHNAMTNYPYVIYYGTLLSNELEKGLEIFSDIIINTEFKEDGFKEEINVI
HHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
IEELNEWDEEVEQYCEDKLFFNSFQNRRIKYPIIGLEDQLESIKLEDIKKFYEEYYFPGN
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCEECCHHHHHHCCHHHHHHHHHHHCCCCC
TSIAVISSLDFEEVKNLVEKYFRLWEKKIKIIEEVCYENNISDTFLDKRDGIKTCKVQMI
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCEEEEEEE
FNIHELNDNEISLLRIFDEYFGQGVNSLLFDTLRTKNGLIYDVITNIAHEKYIKLYKITF
EEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEEEEE
STSKENVDKSIELIKQCINKLAELKNSIDMEDIKQLIKSYKLKKLFKEEKSIVLAKEIST
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCEEEHHHHHH
YDTMFGDYTVYTNENLNNLTKEDIFDVGIKTLENPSIEIIS
HHHHCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA