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The map label for this gene is putA [H]

Identifier: 187930561

GI number: 187930561

Start: 3661312

End: 3665283

Strand: Reverse

Name: putA [H]

Synonym: Rpic_3496

Alternate gene names: 187930561

Gene position: 3665283-3661312 (Counterclockwise)

Preceding gene: 187930562

Following gene: 187930560

Centisome position: 92.97

GC content: 68.05

Gene sequence:

>3972_bases
ATGGCTACAACCACCCTCGGGGTCAAGCTGGACGATGCTTCGCGTGAACGCCTCAAGCGCGTTGCGCAGTCCATTGACCG
CACGCCGCACTGGCTGATCAAGCAGGCGATCTTCACGTATCTGGACCAAGTGGAGCGGGGGCAGCTGCCAAATGACGCAA
ACGGCACGGCGGCGGATGGCCTCCCGTCCGCCGCCGCCGCCGTCTCCGACGTGCATGACGGCGATGACGCCGCGGTGCAA
CCGTTCCTCGAATTTGCGCAAAGCGTGCAACCGCAGTCGGTTCTGCGCGCGGCCATCACCGCAGCCTACCGCCGCCCTGA
AACCGAAGCCATTCCGATGCTGCTCGAGCAGGCCCGCCTGCCGGGCGCGCTCGCCTCGGAAGCCAAGCAGCTCGCGCGGG
ATCTGGCCGGCAAGCTGCGTACGCAAAAGGTCGGCACCGGCCGTGAAGGGCTGGTGCAGGGCCTCATTCAAGAATTCTCC
CTGTCGAGCCAGGAAGGCGTGGCGCTGATGTGCCTGGCCGAAGCGCTGCTGCGCATTCCGGACAAGGCCACGCGCGACGC
GCTCATCCGCGACAAGATCAGCAACGGCAACTGGTATTCGCATGTCGGCCAGAGCCCGTCGCTGTTCGTGAATGCCGCCA
CCTGGGGTCTGCTGCTCACGGGCAAGCTGGTGGCCACGCACAACGAAGCAGGGCTGTCGAAGGCGCTCACGCGCATCATC
GGCAAGAGCGGCGAACCGCTGATCCGCAAGGGTGTGGACATGGCGATGCGCCTGATGGGCGAGCAGTTCGTCACCGGCGA
AACCATTTCCGAAGCGCTGGCCAACGCGCGCAAGTTCGAGGCCGAAGGCTTCCGCTACTCCTACGACATGCTCGGCGAGG
CCGCGATGACGGAGGAAGACGCGCAGCGCTACCTCGCGTCGTACGAGCAGGCCATCCGCGCGATCGGGCAGGCCTCGGGC
GGGCGCGGCATCTACGAAGGGCCGGGCATCTCGATCAAGCTGTCGGCGCTGCACCCGCGCTACAGCCGCGCGCAGTACGA
CCGCACGATCAACGAGCTGTATCCGCGCGTGAAGGCGCTGGCGATGCTGGCGCGTGAATACGACATCGGCATCAACATCG
ACGCCGAAGAGGCCGACCGCCTGGAACTGTCGCTCGACCTGCTCGAGCGCCTGTGCTTTGCGCCCGAGCTGGCCGGCTGG
AACGGCATCGGCTTCGTGGTGCAGGGCTACCAGAAGCGCTGCCCGTTCGTGCTCGACTACATCATCGATCTGGCTCGTCG
CAGCAAGCACCGCCTGATGATCCGCCTCGTAAAGGGCGCGTACTGGGACAGCGAGGTCAAGCGCGCCCAGGTCGACGGCC
TGGAGGGCTACCCGGTCTACACGCGCAAGGTCTACACCGACGTGTCGTACCTGGCCTGCGCGCGCAAGCTGCTGGCCGCG
CCGGAGGCGATCTTCCCGCAGTTCGCCACGCACAACGCGCACACGCTGGCGGCCATTTACCACATGGCCGGCCAGAACTA
TTACCCCGGCCAATACGAATTCCAGTGCCTGCACGGCATGGGCGAGCCGCTGTACGAGCAGGTCGTCGGCAACAAGCCGG
GCAAGCTGAACCGCCCGTGCCGCATCTACGCGCCGGTCGGTACGCACGAAACGCTGCTGGCCTACCTGGTGCGCCGTCTG
CTGGAAAACGGCGCCAACACCTCGTTCGTGAACCGCATTGCGGACGAGTCGATTCCGCTGGACGACCTCGTCGCCGACCC
GGTGGCGGTGGTGGAAAAGATGCACGCCGATGAAGGGACGCTCGGCCTGCCGCATCCGAAGATTCCGCTGCCGCGCGCCC
TTTACGGTGACGTTCGCGCAAACTCGTCGGGCATCGACCTGGCGAACGAGCAGCGCCTGGCGTCGTTGTCGTCCGCCCTT
CTTGCCGGCACCAGCACGGTCTGGACCGCCGAGCCGACGATCGGCGACGCATCGTACGTGGGTGGCGCGCCGCAGCCGGT
GCGCAATCCGGCGGACCTGCGCGACATCGTCGGCCATGTGACGGAAGCCACCGAAGCCGATGTGGATGCCGCGCTGTCGG
CCGCCACCGCCGCCGCCCCGATCTGGCAAGCCACGCCGCCGGAAGCGCGCGCTGCGCTGCTCGATCGCGCCGCCGACTTG
ATGGAAGGCGAGATGCAGCACCTGATGGGCCTGATCATCCGCGAGGCCGGCAAGACGCTGTCCAACGCCATCGCCGAGGT
GCGCGAAGCCGTCGACTTCCTGCGCTATTACGCGGCGCAGGTGCGCGGTGGGTTCTCCAACGACACGCACCGTCCGCTGG
GCCCGGTGGTCTGCATCAGCCCGTGGAACTTCCCGCTGGCGATCTTCACCGGCCAGGTCAGCGCCGCGCTGGCTGCGGGC
AACCCGGTGCTGGCCAAGCCCGCTGAACAGACCCCGCTGATTGCGGCGCAAGCCGTGCGCATCCTGCGCGAAGCCGGCGT
GCCGGCCGGTGCCGTGCAACTGCTGCCGGGCCGCGGTGAGACTGTCGGCGCGGCGCTGGTGAAGGACGGGCGCACCAAGG
GCGTGATGTTCACCGGCTCGACTGAAGTCGCGCGCATCCTGCAGCGCACGCTTGCCGGCCGCCTGGATGCCAACGGCGCG
CCGATTCCGCTGATTGCCGAGACCGGCGGTCAGAACGCGATGATTGTCGATTCGTCGGCGCTGGCTGAGCAGGTGGTGGC
CGATGTGCTGTCGTCTGCGTTTGATTCGGCAGGCCAGCGTTGTTCGGCGCTGCGCGTGCTGTGCCTGCAGGATGACGTCG
CCGACCGCGTGCTCGCGATGCTCAAGGGTGGCATGGCCGAGCTGGCGATGGGCAATCCGGATCGTCTCGCCACCGATGTC
GGCCCGGTGATCGACGCCGAAGCGCGCGACAACATCGTCGGCCACATCGAAGCGATGCGCGCCAAGGGCCGCCGTGTGCA
TCAGGCACCGGTGCCGGCCGCATGCGCGCACGGCACGTTCGTGCCGCCGACGGTGATCGAACTCGACAGCCTGTCGGACC
TGACGCGCGAGATCTTCGGCCCCGTGCTGCACGTGGTGCGCTGGAAGCGTACGGCGGACAACGCTGGCCTGACCAAGCTG
GTCGAACAGATCAACGGCACGGGCTACGGCCTGACGCTGGGCATCCACACGCGCATCGACGAGACCATCGCACACGTGGT
CGACCGCGCGCACGTCGGCAACCTGTATGTGAACCGCAATATCGTCGGCGCCGTGGTGGGCGTGCAGCCGTTCGGCGGCG
AAGGGCTGTCGGGTACGGGCCCGAAGGCCGGCGGCCCGCTGTATCTGCTGCGTCTGCTGTCGACCTGCCCGCAGGACGCC
ATGCGCACCGCAATGCAACTCACCGCTGGTGCCGGTACGGAGGTCGATACCGACGCGCGCCGCGCGCTGCTGGCGCCGTT
CGATGCGCTGACGGAATGGGCACGCCAGCAATCGCCGGAACTGGCGGCGCTGTGCGAGCGCCTGGCTGCAGCCTCGGCCA
CGGGCGCCACCGCCACGCTGCCCGGCCCGACCGGCGAGCGCAACACCTACACGCTGTTGCCGCGCGAAGCCGTGCTGTGC
GTGGCGGCCGATCCGGCGGATTGGCTGCGCCAACTGGCGGCCGTGCTGGCTGTCGGCAGCGTGGCCGTTGTGCAGGAAAA
CCCTGCCATCGAAGCAGTACTTCGGGGCTTGCCGGCGGCAGTACAATCGCGCGTCCGCGTGGTCGGCTCGACCGACGAAG
CGGCGTTTGATGCGGTGCTGCATCACGGCGATTCGGACCATCTGCGCGCCATCTGCGAAGGACTGGCACGACGTGCCGGC
CCGATCGTGGGGGTGCAAGGCCTGCCGCACGGCGGGGAAGGGCTGGCGCTGGAGCGCCTGCTGATCGAGCGTTCGCTGTC
GGTCAATACGGCCGCCGCGGGTGGCAACGCCAGCCTGATGACCATCGGCTGA

Upstream 100 bases:

>100_bases
AGGGGTTTCACTAGGTTGCACCTTCAAGATCGCCAGGCGTATGATCCGCCCAATTTGCCGGCCACAAGCTAGGCAATGGC
AGCTCTGGATAGGAACCCAC

Downstream 100 bases:

>100_bases
CGGGGAGCACGAGCAGGATTCGCGGTTCCATTCGCACGACGGGTGCGGATGGGATGCGAAGCGGGAGGAGGGCGACGGTG
ATCCCGTCGCGCTATTGATC

Product: trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1323; Mature: 1322

Protein sequence:

>1323_residues
MATTTLGVKLDDASRERLKRVAQSIDRTPHWLIKQAIFTYLDQVERGQLPNDANGTAADGLPSAAAAVSDVHDGDDAAVQ
PFLEFAQSVQPQSVLRAAITAAYRRPETEAIPMLLEQARLPGALASEAKQLARDLAGKLRTQKVGTGREGLVQGLIQEFS
LSSQEGVALMCLAEALLRIPDKATRDALIRDKISNGNWYSHVGQSPSLFVNAATWGLLLTGKLVATHNEAGLSKALTRII
GKSGEPLIRKGVDMAMRLMGEQFVTGETISEALANARKFEAEGFRYSYDMLGEAAMTEEDAQRYLASYEQAIRAIGQASG
GRGIYEGPGISIKLSALHPRYSRAQYDRTINELYPRVKALAMLAREYDIGINIDAEEADRLELSLDLLERLCFAPELAGW
NGIGFVVQGYQKRCPFVLDYIIDLARRSKHRLMIRLVKGAYWDSEVKRAQVDGLEGYPVYTRKVYTDVSYLACARKLLAA
PEAIFPQFATHNAHTLAAIYHMAGQNYYPGQYEFQCLHGMGEPLYEQVVGNKPGKLNRPCRIYAPVGTHETLLAYLVRRL
LENGANTSFVNRIADESIPLDDLVADPVAVVEKMHADEGTLGLPHPKIPLPRALYGDVRANSSGIDLANEQRLASLSSAL
LAGTSTVWTAEPTIGDASYVGGAPQPVRNPADLRDIVGHVTEATEADVDAALSAATAAAPIWQATPPEARAALLDRAADL
MEGEMQHLMGLIIREAGKTLSNAIAEVREAVDFLRYYAAQVRGGFSNDTHRPLGPVVCISPWNFPLAIFTGQVSAALAAG
NPVLAKPAEQTPLIAAQAVRILREAGVPAGAVQLLPGRGETVGAALVKDGRTKGVMFTGSTEVARILQRTLAGRLDANGA
PIPLIAETGGQNAMIVDSSALAEQVVADVLSSAFDSAGQRCSALRVLCLQDDVADRVLAMLKGGMAELAMGNPDRLATDV
GPVIDAEARDNIVGHIEAMRAKGRRVHQAPVPAACAHGTFVPPTVIELDSLSDLTREIFGPVLHVVRWKRTADNAGLTKL
VEQINGTGYGLTLGIHTRIDETIAHVVDRAHVGNLYVNRNIVGAVVGVQPFGGEGLSGTGPKAGGPLYLLRLLSTCPQDA
MRTAMQLTAGAGTEVDTDARRALLAPFDALTEWARQQSPELAALCERLAAASATGATATLPGPTGERNTYTLLPREAVLC
VAADPADWLRQLAAVLAVGSVAVVQENPAIEAVLRGLPAAVQSRVRVVGSTDEAAFDAVLHHGDSDHLRAICEGLARRAG
PIVGVQGLPHGGEGLALERLLIERSLSVNTAAAGGNASLMTIG

Sequences:

>Translated_1323_residues
MATTTLGVKLDDASRERLKRVAQSIDRTPHWLIKQAIFTYLDQVERGQLPNDANGTAADGLPSAAAAVSDVHDGDDAAVQ
PFLEFAQSVQPQSVLRAAITAAYRRPETEAIPMLLEQARLPGALASEAKQLARDLAGKLRTQKVGTGREGLVQGLIQEFS
LSSQEGVALMCLAEALLRIPDKATRDALIRDKISNGNWYSHVGQSPSLFVNAATWGLLLTGKLVATHNEAGLSKALTRII
GKSGEPLIRKGVDMAMRLMGEQFVTGETISEALANARKFEAEGFRYSYDMLGEAAMTEEDAQRYLASYEQAIRAIGQASG
GRGIYEGPGISIKLSALHPRYSRAQYDRTINELYPRVKALAMLAREYDIGINIDAEEADRLELSLDLLERLCFAPELAGW
NGIGFVVQGYQKRCPFVLDYIIDLARRSKHRLMIRLVKGAYWDSEVKRAQVDGLEGYPVYTRKVYTDVSYLACARKLLAA
PEAIFPQFATHNAHTLAAIYHMAGQNYYPGQYEFQCLHGMGEPLYEQVVGNKPGKLNRPCRIYAPVGTHETLLAYLVRRL
LENGANTSFVNRIADESIPLDDLVADPVAVVEKMHADEGTLGLPHPKIPLPRALYGDVRANSSGIDLANEQRLASLSSAL
LAGTSTVWTAEPTIGDASYVGGAPQPVRNPADLRDIVGHVTEATEADVDAALSAATAAAPIWQATPPEARAALLDRAADL
MEGEMQHLMGLIIREAGKTLSNAIAEVREAVDFLRYYAAQVRGGFSNDTHRPLGPVVCISPWNFPLAIFTGQVSAALAAG
NPVLAKPAEQTPLIAAQAVRILREAGVPAGAVQLLPGRGETVGAALVKDGRTKGVMFTGSTEVARILQRTLAGRLDANGA
PIPLIAETGGQNAMIVDSSALAEQVVADVLSSAFDSAGQRCSALRVLCLQDDVADRVLAMLKGGMAELAMGNPDRLATDV
GPVIDAEARDNIVGHIEAMRAKGRRVHQAPVPAACAHGTFVPPTVIELDSLSDLTREIFGPVLHVVRWKRTADNAGLTKL
VEQINGTGYGLTLGIHTRIDETIAHVVDRAHVGNLYVNRNIVGAVVGVQPFGGEGLSGTGPKAGGPLYLLRLLSTCPQDA
MRTAMQLTAGAGTEVDTDARRALLAPFDALTEWARQQSPELAALCERLAAASATGATATLPGPTGERNTYTLLPREAVLC
VAADPADWLRQLAAVLAVGSVAVVQENPAIEAVLRGLPAAVQSRVRVVGSTDEAAFDAVLHHGDSDHLRAICEGLARRAG
PIVGVQGLPHGGEGLALERLLIERSLSVNTAAAGGNASLMTIG
>Mature_1322_residues
ATTTLGVKLDDASRERLKRVAQSIDRTPHWLIKQAIFTYLDQVERGQLPNDANGTAADGLPSAAAAVSDVHDGDDAAVQP
FLEFAQSVQPQSVLRAAITAAYRRPETEAIPMLLEQARLPGALASEAKQLARDLAGKLRTQKVGTGREGLVQGLIQEFSL
SSQEGVALMCLAEALLRIPDKATRDALIRDKISNGNWYSHVGQSPSLFVNAATWGLLLTGKLVATHNEAGLSKALTRIIG
KSGEPLIRKGVDMAMRLMGEQFVTGETISEALANARKFEAEGFRYSYDMLGEAAMTEEDAQRYLASYEQAIRAIGQASGG
RGIYEGPGISIKLSALHPRYSRAQYDRTINELYPRVKALAMLAREYDIGINIDAEEADRLELSLDLLERLCFAPELAGWN
GIGFVVQGYQKRCPFVLDYIIDLARRSKHRLMIRLVKGAYWDSEVKRAQVDGLEGYPVYTRKVYTDVSYLACARKLLAAP
EAIFPQFATHNAHTLAAIYHMAGQNYYPGQYEFQCLHGMGEPLYEQVVGNKPGKLNRPCRIYAPVGTHETLLAYLVRRLL
ENGANTSFVNRIADESIPLDDLVADPVAVVEKMHADEGTLGLPHPKIPLPRALYGDVRANSSGIDLANEQRLASLSSALL
AGTSTVWTAEPTIGDASYVGGAPQPVRNPADLRDIVGHVTEATEADVDAALSAATAAAPIWQATPPEARAALLDRAADLM
EGEMQHLMGLIIREAGKTLSNAIAEVREAVDFLRYYAAQVRGGFSNDTHRPLGPVVCISPWNFPLAIFTGQVSAALAAGN
PVLAKPAEQTPLIAAQAVRILREAGVPAGAVQLLPGRGETVGAALVKDGRTKGVMFTGSTEVARILQRTLAGRLDANGAP
IPLIAETGGQNAMIVDSSALAEQVVADVLSSAFDSAGQRCSALRVLCLQDDVADRVLAMLKGGMAELAMGNPDRLATDVG
PVIDAEARDNIVGHIEAMRAKGRRVHQAPVPAACAHGTFVPPTVIELDSLSDLTREIFGPVLHVVRWKRTADNAGLTKLV
EQINGTGYGLTLGIHTRIDETIAHVVDRAHVGNLYVNRNIVGAVVGVQPFGGEGLSGTGPKAGGPLYLLRLLSTCPQDAM
RTAMQLTAGAGTEVDTDARRALLAPFDALTEWARQQSPELAALCERLAAASATGATATLPGPTGERNTYTLLPREAVLCV
AADPADWLRQLAAVLAVGSVAVVQENPAIEAVLRGLPAAVQSRVRVVGSTDEAAFDAVLHHGDSDHLRAICEGLARRAGP
IVGVQGLPHGGEGLALERLLIERSLSVNTAAAGGNASLMTIG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361176, Length=463, Percent_Identity=32.6133909287257, Blast_Score=199, Evalue=2e-50,
Organism=Homo sapiens, GI25777730, Length=463, Percent_Identity=31.7494600431965, Blast_Score=191, Evalue=6e-48,
Organism=Homo sapiens, GI25777732, Length=457, Percent_Identity=31.5098468271335, Blast_Score=187, Evalue=7e-47,
Organism=Homo sapiens, GI25777724, Length=456, Percent_Identity=29.8245614035088, Blast_Score=183, Evalue=1e-45,
Organism=Homo sapiens, GI25777736, Length=484, Percent_Identity=31.6115702479339, Blast_Score=180, Evalue=6e-45,
Organism=Homo sapiens, GI25777734, Length=484, Percent_Identity=31.6115702479339, Blast_Score=180, Evalue=6e-45,
Organism=Homo sapiens, GI238859541, Length=484, Percent_Identity=31.6115702479339, Blast_Score=180, Evalue=7e-45,
Organism=Homo sapiens, GI153266822, Length=453, Percent_Identity=29.8013245033113, Blast_Score=180, Evalue=8e-45,
Organism=Homo sapiens, GI25777728, Length=409, Percent_Identity=29.8288508557457, Blast_Score=164, Evalue=7e-40,
Organism=Homo sapiens, GI12007648, Length=469, Percent_Identity=26.4392324093817, Blast_Score=156, Evalue=2e-37,
Organism=Homo sapiens, GI21614513, Length=425, Percent_Identity=28.4705882352941, Blast_Score=149, Evalue=2e-35,
Organism=Homo sapiens, GI4507229, Length=491, Percent_Identity=28.7169042769857, Blast_Score=143, Evalue=1e-33,
Organism=Homo sapiens, GI115387104, Length=448, Percent_Identity=26.7857142857143, Blast_Score=142, Evalue=3e-33,
Organism=Homo sapiens, GI188035924, Length=469, Percent_Identity=28.5714285714286, Blast_Score=139, Evalue=2e-32,
Organism=Homo sapiens, GI310128093, Length=454, Percent_Identity=28.4140969162996, Blast_Score=138, Evalue=3e-32,
Organism=Homo sapiens, GI310128103, Length=454, Percent_Identity=28.4140969162996, Blast_Score=138, Evalue=4e-32,
Organism=Homo sapiens, GI238814322, Length=427, Percent_Identity=25.5269320843091, Blast_Score=136, Evalue=1e-31,
Organism=Homo sapiens, GI25777721, Length=504, Percent_Identity=27.9761904761905, Blast_Score=134, Evalue=6e-31,
Organism=Homo sapiens, GI11095441, Length=434, Percent_Identity=27.8801843317972, Blast_Score=134, Evalue=7e-31,
Organism=Homo sapiens, GI25777726, Length=456, Percent_Identity=26.9736842105263, Blast_Score=133, Evalue=1e-30,
Organism=Homo sapiens, GI25952152, Length=463, Percent_Identity=26.133909287257, Blast_Score=131, Evalue=4e-30,
Organism=Homo sapiens, GI310128091, Length=396, Percent_Identity=29.040404040404, Blast_Score=117, Evalue=6e-26,
Organism=Homo sapiens, GI310128087, Length=269, Percent_Identity=30.4832713754647, Blast_Score=102, Evalue=3e-21,
Organism=Homo sapiens, GI206597441, Length=437, Percent_Identity=25.1716247139588, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI206597439, Length=437, Percent_Identity=25.1716247139588, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI22907049, Length=437, Percent_Identity=25.1716247139588, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI71773324, Length=405, Percent_Identity=25.679012345679, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI310128089, Length=334, Percent_Identity=27.5449101796407, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI4502043, Length=341, Percent_Identity=25.8064516129032, Blast_Score=89, Evalue=3e-17,
Organism=Homo sapiens, GI238814371, Length=341, Percent_Identity=25.8064516129032, Blast_Score=89, Evalue=3e-17,
Organism=Homo sapiens, GI301500698, Length=482, Percent_Identity=22.4066390041494, Blast_Score=86, Evalue=3e-16,
Organism=Homo sapiens, GI4557303, Length=337, Percent_Identity=24.9258160237389, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI310128099, Length=205, Percent_Identity=30.7317073170732, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI310128095, Length=322, Percent_Identity=27.639751552795, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI310128101, Length=205, Percent_Identity=30.7317073170732, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI73466520, Length=337, Percent_Identity=24.9258160237389, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI73695881, Length=333, Percent_Identity=24.6246246246246, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI73695879, Length=333, Percent_Identity=24.6246246246246, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI310128097, Length=269, Percent_Identity=27.8810408921933, Blast_Score=76, Evalue=2e-13,
Organism=Escherichia coli, GI1787250, Length=1338, Percent_Identity=70.4783258594918, Blast_Score=1865, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=463, Percent_Identity=30.8855291576674, Blast_Score=176, Evalue=1e-44,
Organism=Escherichia coli, GI1788042, Length=460, Percent_Identity=31.5217391304348, Blast_Score=165, Evalue=2e-41,
Organism=Escherichia coli, GI1787558, Length=445, Percent_Identity=31.4606741573034, Blast_Score=162, Evalue=2e-40,
Organism=Escherichia coli, GI87081896, Length=482, Percent_Identity=29.8755186721992, Blast_Score=158, Evalue=2e-39,
Organism=Escherichia coli, GI1787715, Length=455, Percent_Identity=31.8681318681319, Blast_Score=158, Evalue=2e-39,
Organism=Escherichia coli, GI1787684, Length=478, Percent_Identity=28.8702928870293, Blast_Score=152, Evalue=2e-37,
Organism=Escherichia coli, GI87082295, Length=474, Percent_Identity=27.8481012658228, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI1786504, Length=461, Percent_Identity=28.1995661605206, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI87081926, Length=407, Percent_Identity=27.027027027027, Blast_Score=120, Evalue=5e-28,
Organism=Escherichia coli, GI1787653, Length=406, Percent_Identity=23.1527093596059, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25144435, Length=457, Percent_Identity=31.9474835886214, Blast_Score=184, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI17562198, Length=456, Percent_Identity=31.5789473684211, Blast_Score=177, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17534447, Length=496, Percent_Identity=30.8467741935484, Blast_Score=174, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI32564736, Length=413, Percent_Identity=32.2033898305085, Blast_Score=171, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI115534176, Length=467, Percent_Identity=29.9785867237687, Blast_Score=157, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI133930964, Length=474, Percent_Identity=28.4810126582279, Blast_Score=150, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI115532534, Length=362, Percent_Identity=32.5966850828729, Blast_Score=147, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI25143874, Length=445, Percent_Identity=28.314606741573, Blast_Score=145, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI25143876, Length=445, Percent_Identity=28.314606741573, Blast_Score=144, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17551164, Length=442, Percent_Identity=27.3755656108597, Blast_Score=137, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71986308, Length=428, Percent_Identity=28.2710280373832, Blast_Score=135, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71995606, Length=448, Percent_Identity=27.2321428571429, Blast_Score=127, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17534119, Length=483, Percent_Identity=25.0517598343685, Blast_Score=125, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI32564151, Length=429, Percent_Identity=28.2051282051282, Blast_Score=124, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI71995613, Length=405, Percent_Identity=26.9135802469136, Blast_Score=123, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI71990744, Length=314, Percent_Identity=29.2993630573248, Blast_Score=106, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI25146391, Length=335, Percent_Identity=25.6716417910448, Blast_Score=92, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32566756, Length=335, Percent_Identity=25.6716417910448, Blast_Score=92, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25146394, Length=335, Percent_Identity=25.6716417910448, Blast_Score=92, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17564084, Length=334, Percent_Identity=26.0479041916168, Blast_Score=83, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325196, Length=466, Percent_Identity=31.7596566523605, Blast_Score=190, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6320917, Length=458, Percent_Identity=31.6593886462882, Blast_Score=186, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6321826, Length=482, Percent_Identity=30.2904564315353, Blast_Score=174, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6323821, Length=446, Percent_Identity=32.0627802690583, Blast_Score=173, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6324950, Length=451, Percent_Identity=28.159645232816, Blast_Score=168, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6323822, Length=449, Percent_Identity=30.7349665924276, Blast_Score=166, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6319478, Length=472, Percent_Identity=26.6949152542373, Blast_Score=134, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6321828, Length=487, Percent_Identity=24.0246406570842, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323757, Length=329, Percent_Identity=24.3161094224924, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI20129399, Length=449, Percent_Identity=30.2895322939866, Blast_Score=182, Evalue=1e-45,
Organism=Drosophila melanogaster, GI281362580, Length=451, Percent_Identity=28.8248337028825, Blast_Score=182, Evalue=2e-45,
Organism=Drosophila melanogaster, GI62472918, Length=451, Percent_Identity=28.8248337028825, Blast_Score=182, Evalue=2e-45,
Organism=Drosophila melanogaster, GI62472926, Length=451, Percent_Identity=28.8248337028825, Blast_Score=182, Evalue=2e-45,
Organism=Drosophila melanogaster, GI62472936, Length=451, Percent_Identity=28.8248337028825, Blast_Score=182, Evalue=2e-45,
Organism=Drosophila melanogaster, GI21356737, Length=451, Percent_Identity=28.8248337028825, Blast_Score=182, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24650465, Length=460, Percent_Identity=30.2173913043478, Blast_Score=180, Evalue=5e-45,
Organism=Drosophila melanogaster, GI24668425, Length=529, Percent_Identity=27.7882797731569, Blast_Score=174, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24668417, Length=529, Percent_Identity=27.7882797731569, Blast_Score=174, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24668413, Length=529, Percent_Identity=27.7882797731569, Blast_Score=174, Evalue=3e-43,
Organism=Drosophila melanogaster, GI28571802, Length=485, Percent_Identity=28.2474226804124, Blast_Score=155, Evalue=3e-37,
Organism=Drosophila melanogaster, GI28571800, Length=485, Percent_Identity=28.2474226804124, Blast_Score=155, Evalue=3e-37,
Organism=Drosophila melanogaster, GI28571798, Length=485, Percent_Identity=28.2474226804124, Blast_Score=155, Evalue=3e-37,
Organism=Drosophila melanogaster, GI28571796, Length=485, Percent_Identity=28.2474226804124, Blast_Score=155, Evalue=3e-37,
Organism=Drosophila melanogaster, GI28571794, Length=485, Percent_Identity=28.2474226804124, Blast_Score=155, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24585660, Length=457, Percent_Identity=26.0393873085339, Blast_Score=154, Evalue=3e-37,
Organism=Drosophila melanogaster, GI28571806, Length=485, Percent_Identity=28.2474226804124, Blast_Score=154, Evalue=3e-37,
Organism=Drosophila melanogaster, GI28574525, Length=489, Percent_Identity=26.9938650306748, Blast_Score=147, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24666674, Length=469, Percent_Identity=28.997867803838, Blast_Score=132, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24638876, Length=426, Percent_Identity=27.9342723004695, Blast_Score=111, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24638878, Length=426, Percent_Identity=27.9342723004695, Blast_Score=111, Evalue=4e-24,
Organism=Drosophila melanogaster, GI281360299, Length=342, Percent_Identity=27.7777777777778, Blast_Score=98, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281360297, Length=342, Percent_Identity=27.7777777777778, Blast_Score=98, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281360295, Length=342, Percent_Identity=27.7777777777778, Blast_Score=98, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24586250, Length=342, Percent_Identity=27.7777777777778, Blast_Score=98, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281360301, Length=338, Percent_Identity=27.810650887574, Blast_Score=98, Evalue=4e-20,
Organism=Drosophila melanogaster, GI45552499, Length=342, Percent_Identity=26.0233918128655, Blast_Score=92, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281360303, Length=342, Percent_Identity=26.0233918128655, Blast_Score=91, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 141112; Mature: 140980

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTTLGVKLDDASRERLKRVAQSIDRTPHWLIKQAIFTYLDQVERGQLPNDANGTAADG
CCCEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
LPSAAAAVSDVHDGDDAAVQPFLEFAQSVQPQSVLRAAITAAYRRPETEAIPMLLEQARL
CCHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
PGALASEAKQLARDLAGKLRTQKVGTGREGLVQGLIQEFSLSSQEGVALMCLAEALLRIP
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
DKATRDALIRDKISNGNWYSHVGQSPSLFVNAATWGLLLTGKLVATHNEAGLSKALTRII
CHHHHHHHHHHHCCCCCHHHHCCCCCCEEEEHHHHHHHEECEEEEECCHHHHHHHHHHHH
GKSGEPLIRKGVDMAMRLMGEQFVTGETISEALANARKFEAEGFRYSYDMLGEAAMTEED
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCHHH
AQRYLASYEQAIRAIGQASGGRGIYEGPGISIKLSALHPRYSRAQYDRTINELYPRVKAL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
AMLAREYDIGINIDAEEADRLELSLDLLERLCFAPELAGWNGIGFVVQGYQKRCPFVLDY
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEECHHHCCCHHHHH
IIDLARRSKHRLMIRLVKGAYWDSEVKRAQVDGLEGYPVYTRKVYTDVSYLACARKLLAA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHC
PEAIFPQFATHNAHTLAAIYHMAGQNYYPGQYEFQCLHGMGEPLYEQVVGNKPGKLNRPC
CHHHCCHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHCCCCCCCCCCE
RIYAPVGTHETLLAYLVRRLLENGANTSFVNRIADESIPLDDLVADPVAVVEKMHADEGT
EEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHCCHHHHHHHHHCCCCC
LGLPHPKIPLPRALYGDVRANSSGIDLANEQRLASLSSALLAGTSTVWTAEPTIGDASYV
CCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHC
GGAPQPVRNPADLRDIVGHVTEATEADVDAALSAATAAAPIWQATPPEARAALLDRAADL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
MEGEMQHLMGLIIREAGKTLSNAIAEVREAVDFLRYYAAQVRGGFSNDTHRPLGPVVCIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEC
PWNFPLAIFTGQVSAALAAGNPVLAKPAEQTPLIAAQAVRILREAGVPAGAVQLLPGRGE
CCCCCEEEEECCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCC
TVGAALVKDGRTKGVMFTGSTEVARILQRTLAGRLDANGAPIPLIAETGGQNAMIVDSSA
HHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCEEEECHHH
LAEQVVADVLSSAFDSAGQRCSALRVLCLQDDVADRVLAMLKGGMAELAMGNPDRLATDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHC
GPVIDAEARDNIVGHIEAMRAKGRRVHQAPVPAACAHGTFVPPTVIELDSLSDLTREIFG
CCCCCCHHHCHHHHHHHHHHHCCCEECCCCCCCHHCCCCCCCCHHEEHHHHHHHHHHHHH
PVLHVVRWKRTADNAGLTKLVEQINGTGYGLTLGIHTRIDETIAHVVDRAHVGNLYVNRN
HHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCEEECCC
IVGAVVGVQPFGGEGLSGTGPKAGGPLYLLRLLSTCPQDAMRTAMQLTAGAGTEVDTDAR
EEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHH
RALLAPFDALTEWARQQSPELAALCERLAAASATGATATLPGPTGERNTYTLLPREAVLC
HHHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCEEEECCCCEEEE
VAADPADWLRQLAAVLAVGSVAVVQENPAIEAVLRGLPAAVQSRVRVVGSTDEAAFDAVL
EECCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHCCCHHHHHHHEEECCCCHHHHHHHH
HHGDSDHLRAICEGLARRAGPIVGVQGLPHGGEGLALERLLIERSLSVNTAAAGGNASLM
HCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCEECCCCCCEEE
TIG
EEC
>Mature Secondary Structure 
ATTTLGVKLDDASRERLKRVAQSIDRTPHWLIKQAIFTYLDQVERGQLPNDANGTAADG
CCEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
LPSAAAAVSDVHDGDDAAVQPFLEFAQSVQPQSVLRAAITAAYRRPETEAIPMLLEQARL
CCHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
PGALASEAKQLARDLAGKLRTQKVGTGREGLVQGLIQEFSLSSQEGVALMCLAEALLRIP
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
DKATRDALIRDKISNGNWYSHVGQSPSLFVNAATWGLLLTGKLVATHNEAGLSKALTRII
CHHHHHHHHHHHCCCCCHHHHCCCCCCEEEEHHHHHHHEECEEEEECCHHHHHHHHHHHH
GKSGEPLIRKGVDMAMRLMGEQFVTGETISEALANARKFEAEGFRYSYDMLGEAAMTEED
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCHHH
AQRYLASYEQAIRAIGQASGGRGIYEGPGISIKLSALHPRYSRAQYDRTINELYPRVKAL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
AMLAREYDIGINIDAEEADRLELSLDLLERLCFAPELAGWNGIGFVVQGYQKRCPFVLDY
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEECHHHCCCHHHHH
IIDLARRSKHRLMIRLVKGAYWDSEVKRAQVDGLEGYPVYTRKVYTDVSYLACARKLLAA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHC
PEAIFPQFATHNAHTLAAIYHMAGQNYYPGQYEFQCLHGMGEPLYEQVVGNKPGKLNRPC
CHHHCCHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHCCCCCCCCCCE
RIYAPVGTHETLLAYLVRRLLENGANTSFVNRIADESIPLDDLVADPVAVVEKMHADEGT
EEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHCCHHHHHHHHHCCCCC
LGLPHPKIPLPRALYGDVRANSSGIDLANEQRLASLSSALLAGTSTVWTAEPTIGDASYV
CCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHC
GGAPQPVRNPADLRDIVGHVTEATEADVDAALSAATAAAPIWQATPPEARAALLDRAADL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
MEGEMQHLMGLIIREAGKTLSNAIAEVREAVDFLRYYAAQVRGGFSNDTHRPLGPVVCIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEC
PWNFPLAIFTGQVSAALAAGNPVLAKPAEQTPLIAAQAVRILREAGVPAGAVQLLPGRGE
CCCCCEEEEECCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCC
TVGAALVKDGRTKGVMFTGSTEVARILQRTLAGRLDANGAPIPLIAETGGQNAMIVDSSA
HHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCEEEECHHH
LAEQVVADVLSSAFDSAGQRCSALRVLCLQDDVADRVLAMLKGGMAELAMGNPDRLATDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHC
GPVIDAEARDNIVGHIEAMRAKGRRVHQAPVPAACAHGTFVPPTVIELDSLSDLTREIFG
CCCCCCHHHCHHHHHHHHHHHCCCEECCCCCCCHHCCCCCCCCHHEEHHHHHHHHHHHHH
PVLHVVRWKRTADNAGLTKLVEQINGTGYGLTLGIHTRIDETIAHVVDRAHVGNLYVNRN
HHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCEEECCC
IVGAVVGVQPFGGEGLSGTGPKAGGPLYLLRLLSTCPQDAMRTAMQLTAGAGTEVDTDAR
EEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHH
RALLAPFDALTEWARQQSPELAALCERLAAASATGATATLPGPTGERNTYTLLPREAVLC
HHHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCEEEECCCCEEEE
VAADPADWLRQLAAVLAVGSVAVVQENPAIEAVLRGLPAAVQSRVRVVGSTDEAAFDAVL
EECCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHCCCHHHHHHHEEECCCCHHHHHHHH
HHGDSDHLRAICEGLARRAGPIVGVQGLPHGGEGLALERLLIERSLSVNTAAAGGNASLM
HCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCEECCCCCCEEE
TIG
EEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]