Click here to switch to the map view.

The map label for this gene is livK [C]

Identifier: 187930560

GI number: 187930560

Start: 3660036

End: 3661181

Strand: Reverse

Name: livK [C]

Synonym: Rpic_3495

Alternate gene names: 187930560

Gene position: 3661181-3660036 (Counterclockwise)

Preceding gene: 187930561

Following gene: 187930559

Centisome position: 92.86

GC content: 63.7

Gene sequence:

>1146_bases
ATGAAATTGAAGCAACTGTGTCTGGCGGCAGCACTGTGCACGCTGGCGGGTGGTGCAATGACGGCGGCATCGGCCCAGGA
AGTCATCAAGCTGGGCTTTGCTGCCCCGATGTCGGGTCCGCAAGCGCAATACGGCACGGACATGAAGAACGGCGCGACGC
TGGCCGTTGAAGAGTTCAACGCCACCAAGCCGAAGATCGCCGGCAAGGACGTCAAGTTCCAGCTCATGGCGGAAGATGAC
CAGGCTGACCCGAAGACCGGTACGGCAGTCGCCCAGAAGCTGGTGGACAGCGGCATCAAGGGCATGCTCGGCCACTTCAA
TTCGGGTACCAGCATCCCGGCGTCGCGCGTGTACAACCAGGCCGGCATCGCGCAGATCGCCATGGCAACCGCGCCGGAAT
ACACCAAGCAAGGCTACAAGACGACGTTCCGCATGATGACTTCCGATACCCAGCAGGGTTCGGTGGTCGGCACGTTCGCC
GTCAAGAAGCTGGGCTACAAGAACATCGCCATCGTGGATGACCGCACGGCCTACGGCCAGGGTCTGGCCGACGAGTTCGA
GAAGGCTGCCAAGGCTGCCGGCGCCACCATCGTGCGTCGCGAATTCACCAACGACAAGGCCAGCGACTTCAAGGCCATCC
TCACGCAGATCAAGAGCAAGAACCCGGACGCCGTGTTCTACGGCGGCGCCGAAGGCCAATCGGCGCCGCTGCTCAAGCAG
ATGCGCGAGCTGGGCATGAAGTCCACGCTCATGTCGGGCGAAATGTCCAAGACCGACGACTTCATCAAGCTGGCCGGCCC
GCAAGCGGCGGAAGGCATGGTGGCATCGCTGGCCGGTCTGCCGCTGGAGCAGATGCCGGGCGGCGCTGGCTACAAGGCCC
GCTATGAGAAGCGTTTCGGCACGCCGGTGCAGACGTACTCGCCGTACGCCTACGACGGCGCGATGGCCCTGATGAAGGCG
ATGGTGGCTGCGGGTTCGTCCGACCCGGCCAAGTACCTGCCGATCCTGGCTGCCACCAACACGCAAGGCGTGACCGCCAA
GCACTACGCCTACGACGACAAGGGCGACCTGAAGGACGGCGGCATCACCGTCTACAAGGTCACCGGCGGCAAGTGGACGC
CGCTGGAGAGCGTGGGCGGCAAGTAA

Upstream 100 bases:

>100_bases
TTCGCACGACGGGTGCGGATGGGATGCGAAGCGGGAGGAGGGCGACGGTGATCCCGTCGCGCTATTGATCCAAATTGCGT
TTGAACTAGGAGACGCACAA

Downstream 100 bases:

>100_bases
TCCGACCGGCTCTCAGCCATTCGCAGTATGAAAACCGCCCTCCGGGGCGGTTTTTCTTTTCCGGCGGCCAGAGGCGCAGA
ACATAGAGTTGTCGCCATCT

Product: extracellular ligand-binding receptor

Products: ADP; phosphate; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKLKQLCLAAALCTLAGGAMTAASAQEVIKLGFAAPMSGPQAQYGTDMKNGATLAVEEFNATKPKIAGKDVKFQLMAEDD
QADPKTGTAVAQKLVDSGIKGMLGHFNSGTSIPASRVYNQAGIAQIAMATAPEYTKQGYKTTFRMMTSDTQQGSVVGTFA
VKKLGYKNIAIVDDRTAYGQGLADEFEKAAKAAGATIVRREFTNDKASDFKAILTQIKSKNPDAVFYGGAEGQSAPLLKQ
MRELGMKSTLMSGEMSKTDDFIKLAGPQAAEGMVASLAGLPLEQMPGGAGYKARYEKRFGTPVQTYSPYAYDGAMALMKA
MVAAGSSDPAKYLPILAATNTQGVTAKHYAYDDKGDLKDGGITVYKVTGGKWTPLESVGGK

Sequences:

>Translated_381_residues
MKLKQLCLAAALCTLAGGAMTAASAQEVIKLGFAAPMSGPQAQYGTDMKNGATLAVEEFNATKPKIAGKDVKFQLMAEDD
QADPKTGTAVAQKLVDSGIKGMLGHFNSGTSIPASRVYNQAGIAQIAMATAPEYTKQGYKTTFRMMTSDTQQGSVVGTFA
VKKLGYKNIAIVDDRTAYGQGLADEFEKAAKAAGATIVRREFTNDKASDFKAILTQIKSKNPDAVFYGGAEGQSAPLLKQ
MRELGMKSTLMSGEMSKTDDFIKLAGPQAAEGMVASLAGLPLEQMPGGAGYKARYEKRFGTPVQTYSPYAYDGAMALMKA
MVAAGSSDPAKYLPILAATNTQGVTAKHYAYDDKGDLKDGGITVYKVTGGKWTPLESVGGK
>Mature_381_residues
MKLKQLCLAAALCTLAGGAMTAASAQEVIKLGFAAPMSGPQAQYGTDMKNGATLAVEEFNATKPKIAGKDVKFQLMAEDD
QADPKTGTAVAQKLVDSGIKGMLGHFNSGTSIPASRVYNQAGIAQIAMATAPEYTKQGYKTTFRMMTSDTQQGSVVGTFA
VKKLGYKNIAIVDDRTAYGQGLADEFEKAAKAAGATIVRREFTNDKASDFKAILTQIKSKNPDAVFYGGAEGQSAPLLKQ
MRELGMKSTLMSGEMSKTDDFIKLAGPQAAEGMVASLAGLPLEQMPGGAGYKARYEKRFGTPVQTYSPYAYDGAMALMKA
MVAAGSSDPAKYLPILAATNTQGVTAKHYAYDDKGDLKDGGITVYKVTGGKWTPLESVGGK

Specific function: Component of an amino-acid transport system (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the leucine-binding protein family [H]

Homologues:

Organism=Escherichia coli, GI1789867, Length=372, Percent_Identity=31.989247311828, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI48994941, Length=359, Percent_Identity=32.8690807799443, Blast_Score=155, Evalue=3e-39,

Paralogues:

None

Copy number: 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001828
- InterPro:   IPR000709 [H]

Pfam domain/function: PF01094 ANF_receptor [H]

EC number: NA

Molecular weight: Translated: 40114; Mature: 40114

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKQLCLAAALCTLAGGAMTAASAQEVIKLGFAAPMSGPQAQYGTDMKNGATLAVEEFN
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCC
ATKPKIAGKDVKFQLMAEDDQADPKTGTAVAQKLVDSGIKGMLGHFNSGTSIPASRVYNQ
CCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
AGIAQIAMATAPEYTKQGYKTTFRMMTSDTQQGSVVGTFAVKKLGYKNIAIVDDRTAYGQ
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHCCCCCEEEEECCCHHCC
GLADEFEKAAKAAGATIVRREFTNDKASDFKAILTQIKSKNPDAVFYGGAEGQSAPLLKQ
CHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHH
MRELGMKSTLMSGEMSKTDDFIKLAGPQAAEGMVASLAGLPLEQMPGGAGYKARYEKRFG
HHHCCHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHCC
TPVQTYSPYAYDGAMALMKAMVAAGSSDPAKYLPILAATNTQGVTAKHYAYDDKGDLKDG
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHEEEEEECCCCCCEEEEECCCCCCCCCCC
GITVYKVTGGKWTPLESVGGK
CEEEEEECCCCCCCHHHCCCC
>Mature Secondary Structure
MKLKQLCLAAALCTLAGGAMTAASAQEVIKLGFAAPMSGPQAQYGTDMKNGATLAVEEFN
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCC
ATKPKIAGKDVKFQLMAEDDQADPKTGTAVAQKLVDSGIKGMLGHFNSGTSIPASRVYNQ
CCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
AGIAQIAMATAPEYTKQGYKTTFRMMTSDTQQGSVVGTFAVKKLGYKNIAIVDDRTAYGQ
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHCCCCCEEEEECCCHHCC
GLADEFEKAAKAAGATIVRREFTNDKASDFKAILTQIKSKNPDAVFYGGAEGQSAPLLKQ
CHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHH
MRELGMKSTLMSGEMSKTDDFIKLAGPQAAEGMVASLAGLPLEQMPGGAGYKARYEKRFG
HHHCCHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHCC
TPVQTYSPYAYDGAMALMKAMVAAGSSDPAKYLPILAATNTQGVTAKHYAYDDKGDLKDG
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHEEEEEECCCCCCEEEEECCCCCCCCCCC
GITVYKVTGGKWTPLESVGGK
CEEEEEECCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA