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The map label for this gene is oxyR [H]

Identifier: 187930021

GI number: 187930021

Start: 3074081

End: 3075028

Strand: Reverse

Name: oxyR [H]

Synonym: Rpic_2953

Alternate gene names: 187930021

Gene position: 3075028-3074081 (Counterclockwise)

Preceding gene: 187930023

Following gene: 187930019

Centisome position: 78.0

GC content: 65.4

Gene sequence:

>948_bases
ATGACGCTCACCGAACTCAAATACATCGTCGCCGTTGCGCGGGAACGCCACTTTGGGCGTGCCGCCGAGGCCTGCTTCGT
CTCGCAGCCGACGCTGTCGGTCGCCATCAAGAAGCTGGAAGACGAGCTGGCCGTGCAGATCTTCGAGCGCGGCGCGTCGG
AAGTGAGCGTCACGCCTGTCGGCGAGCAGATCGTCACGCAGGCGCAGCGTGTGCTTGAACAGACGATGGCGATCCGCGAG
ATCGCCAAGCAGGGGATGGACCCCCTGGCCGGGCCGCTGCGGCTCGGGGTGATTTATACGATCGGCCCGTATCTGCTGCC
CGCGCTGGTCAAGCAGATGATCGACACCGTCCCGCAGATGCCGCTGATGCTGCAGGAGAACTTCACCGTGCGGCTGGTGG
AGCTGCTCAAGCAGGGCGAGATCGACTGCGCCATCATGGCCGAGCCGTTTCCGGAAGCCGGCCTGATGACGGTGCCGCTG
TACGACGAGCCCTTTGTCGTGGCGGTGCCGCGCGGCCACGAACTGGCGAAGGCGTCGTCGGTGGACCCAGCGGCGCTCAA
GCAGCAAACCATGCTGCTGCTCGGCAACGGCCATTGCTTCCGCGACCACGTGCTGGGCGTGTGCCCGGAGCTGTCGCGTT
TCTCGCAGAATGCGGACGGCATCCAGAAAACCTTCGAGGGTTCGTCGCTGGAAACGATTCGCCATATGGTCGCCAGCGGC
GTGGGCATTACCGTCCTGCCGCGTACTTCGGTGCCGAACATGCAGCCTGCCGCCACCGATCTGCTGACCTACGTGCCCTT
TCAGGAGCCGGTGCCCGACCGCCGCGTTGTGCTGGCCTGGCGCAAGAGTTTCACCCGCATCGCCGCGATCGAAGCGGTGG
CCATGGCGGTCGCGCAATGCAACCTGCCCGGCATCAAGCTGTTGCCGCCCACACCGCTCGTTCACTGA

Upstream 100 bases:

>100_bases
GGATGGCAGCGTTGTCAATGCCGGACCGCCATTCGAACCCCAAGCAACATCGCACGTCCCTTGGTAAAATCTATCGACAT
CTCCAAGCCGATTGATCGCC

Downstream 100 bases:

>100_bases
TCTCCTGATTGGTGCGTTGACCGTTGTCGGCATAGCGAAGAAAATTAGAAAAAGCGCCGACCTGACTGGCGAGAATAGCG
AAGTAAGTTAGAAAAAATAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MTLTELKYIVAVARERHFGRAAEACFVSQPTLSVAIKKLEDELAVQIFERGASEVSVTPVGEQIVTQAQRVLEQTMAIRE
IAKQGMDPLAGPLRLGVIYTIGPYLLPALVKQMIDTVPQMPLMLQENFTVRLVELLKQGEIDCAIMAEPFPEAGLMTVPL
YDEPFVVAVPRGHELAKASSVDPAALKQQTMLLLGNGHCFRDHVLGVCPELSRFSQNADGIQKTFEGSSLETIRHMVASG
VGITVLPRTSVPNMQPAATDLLTYVPFQEPVPDRRVVLAWRKSFTRIAAIEAVAMAVAQCNLPGIKLLPPTPLVH

Sequences:

>Translated_315_residues
MTLTELKYIVAVARERHFGRAAEACFVSQPTLSVAIKKLEDELAVQIFERGASEVSVTPVGEQIVTQAQRVLEQTMAIRE
IAKQGMDPLAGPLRLGVIYTIGPYLLPALVKQMIDTVPQMPLMLQENFTVRLVELLKQGEIDCAIMAEPFPEAGLMTVPL
YDEPFVVAVPRGHELAKASSVDPAALKQQTMLLLGNGHCFRDHVLGVCPELSRFSQNADGIQKTFEGSSLETIRHMVASG
VGITVLPRTSVPNMQPAATDLLTYVPFQEPVPDRRVVLAWRKSFTRIAAIEAVAMAVAQCNLPGIKLLPPTPLVH
>Mature_314_residues
TLTELKYIVAVARERHFGRAAEACFVSQPTLSVAIKKLEDELAVQIFERGASEVSVTPVGEQIVTQAQRVLEQTMAIREI
AKQGMDPLAGPLRLGVIYTIGPYLLPALVKQMIDTVPQMPLMLQENFTVRLVELLKQGEIDCAIMAEPFPEAGLMTVPLY
DEPFVVAVPRGHELAKASSVDPAALKQQTMLLLGNGHCFRDHVLGVCPELSRFSQNADGIQKTFEGSSLETIRHMVASGV
GITVLPRTSVPNMQPAATDLLTYVPFQEPVPDRRVVLAWRKSFTRIAAIEAVAMAVAQCNLPGIKLLPPTPLVH

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=297, Percent_Identity=39.3939393939394, Blast_Score=210, Evalue=7e-56,
Organism=Escherichia coli, GI157672245, Length=309, Percent_Identity=27.831715210356, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788748, Length=295, Percent_Identity=28.8135593220339, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI2367136, Length=272, Percent_Identity=27.9411764705882, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787530, Length=292, Percent_Identity=25.6849315068493, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI145693105, Length=285, Percent_Identity=27.3684210526316, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788887, Length=302, Percent_Identity=26.4900662251656, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787879, Length=294, Percent_Identity=26.8707482993197, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787601, Length=143, Percent_Identity=32.1678321678322, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788296, Length=252, Percent_Identity=25.7936507936508, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788481, Length=265, Percent_Identity=24.5283018867925, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081904, Length=177, Percent_Identity=32.7683615819209, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788297, Length=270, Percent_Identity=25.5555555555556, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082132, Length=252, Percent_Identity=24.2063492063492, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787806, Length=288, Percent_Identity=22.5694444444444, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790208, Length=149, Percent_Identity=32.2147651006711, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790262, Length=263, Percent_Identity=25.4752851711027, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789506, Length=291, Percent_Identity=19.5876288659794, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34424; Mature: 34293

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTELKYIVAVARERHFGRAAEACFVSQPTLSVAIKKLEDELAVQIFERGASEVSVTPV
CCHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
GEQIVTQAQRVLEQTMAIREIAKQGMDPLAGPLRLGVIYTIGPYLLPALVKQMIDTVPQM
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PLMLQENFTVRLVELLKQGEIDCAIMAEPFPEAGLMTVPLYDEPFVVAVPRGHELAKASS
CEECCCCCHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCEEEEECCCCHHHHCCC
VDPAALKQQTMLLLGNGHCFRDHVLGVCPELSRFSQNADGIQKTFEGSSLETIRHMVASG
CCHHHHHHCEEEEEECCCCHHHHHHHCCHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHCC
VGITVLPRTSVPNMQPAATDLLTYVPFQEPVPDRRVVLAWRKSFTRIAAIEAVAMAVAQC
CCEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
NLPGIKLLPPTPLVH
CCCCEEECCCCCCCC
>Mature Secondary Structure 
TLTELKYIVAVARERHFGRAAEACFVSQPTLSVAIKKLEDELAVQIFERGASEVSVTPV
CHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
GEQIVTQAQRVLEQTMAIREIAKQGMDPLAGPLRLGVIYTIGPYLLPALVKQMIDTVPQM
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PLMLQENFTVRLVELLKQGEIDCAIMAEPFPEAGLMTVPLYDEPFVVAVPRGHELAKASS
CEECCCCCHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCEEEEECCCCHHHHCCC
VDPAALKQQTMLLLGNGHCFRDHVLGVCPELSRFSQNADGIQKTFEGSSLETIRHMVASG
CCHHHHHHCEEEEEECCCCHHHHHHHCCHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHCC
VGITVLPRTSVPNMQPAATDLLTYVPFQEPVPDRRVVLAWRKSFTRIAAIEAVAMAVAQC
CCEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
NLPGIKLLPPTPLVH
CCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA