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The map label for this gene is recG [H]

Identifier: 187930023

GI number: 187930023

Start: 3076606

End: 3078753

Strand: Reverse

Name: recG [H]

Synonym: Rpic_2955

Alternate gene names: 187930023

Gene position: 3078753-3076606 (Counterclockwise)

Preceding gene: 187930029

Following gene: 187930021

Centisome position: 78.09

GC content: 67.6

Gene sequence:

>2148_bases
ATGCCCGACGCTGATACTGCGCCGGCGCCGAAGCCAAAACGCGCGGCCACGGCAGACAAGCCAGCCAAGGCAACGGCCAA
AACTGCCCGCCCAGCAGACAAGCTCGCCAAGCTCGGCCTGCACCGCGACGTCGATCTCGTCCTCCATCTGCCGATGCGCT
ACGAGGATGAAACCACGCTGCTGACCATTGCCGAGGCCACGGCCCGCGCCAACACCGGCTGGGCTGCGCAGGTGGAAGGC
ACGGTCACGCGCAATGAAGTGGCGTTTCGGCCGCGTCGGCAGCTCGTCGTGCATATCGCCGATGACTCGGGCGAGCTGGT
CCTGCGCTTTCTCAATTTCTACGGCAGCCAGGTCAAGCAGATGGCCGAAGGCGTGCGCCTGCGCGTGCGCGGCGAAGTGC
GCGGCGGCTTCTTCGGCGCCGAGATGGTGCACCCGACCGTGCGCGCCGTGGCGGACGATGAGCCGCTGCCCGATCGCCTG
ACACCGGTGTATCCGAGCACGGCCGGCGTGGCGCAGGCCTATCTGCGCAAGGCGATCCTGAACGCGCTCACGCGCACGCC
GCTGCCGGAAACGCTGCCGAACAGCCTCGTCACCGGCCCGCTCGCGCCGCTCAAGCTGATGACGCCGGCCGACGCCGTGC
GCCTGCTGCATCAGCCGATGCCCGATGTCGATGAGCACAGCCTCGTCGAGCGCACGCACCCGGCGTGGCTGCGCATCAAG
TTTGATGAACTACTGTCGCAGCAGTTGTCGCTCAAGCGTGCGCAGGCCGCGCGCCGCATGCGCAACGCGCCCATCCTGCG
CGACAGCGGCAAGGATGGGCTGCTCGCGCGCTTCATGGATGCGCTGCCGTTCAAGCTGACCGGCGCCCAGGCCCGCGTGT
GGGAAGAGATTCGCGCCGATCTCGCGCACCCGTACCCGATGCAGCGGTTGCTGCAGGGCGATGTGGGCAGCGGCAAGACC
GTCATTGCCGCGCTGGCAGCCTGCCAGGCCATCGATGCGGGCTGGCAGGCGGCGCTGATGGCGCCGACAGAACTGTTGGC
CGAGCAGCACTATCGCAAGCTTTCTGCGTGGCTCGAACCGCTTGGCGTGGACATCGTCTGGCTGGCCGGCAGCCTCAAGC
GCAAGCAGAAGGACGAGGCGGCGGCGCGCGTGGCGGCCGGCACGGCGCAACTCGTGATCGGTACGCACGCGCTGATCCAG
GATGCGGTCACGTTCGCGCGGCTCGGCCTGGCGGTGGTCGATGAACAGCATCGCTTCGGCGTGGCGCAGCGGCTCGCCCT
GCGCGGCAAGGCGAGCAACGGCGACGGCCCCGCCGCCAACGTCCAGGTGCCGCACCAACTGATGATGTCCGCCACGCCGA
TCCCGCGCACGCTGGCGATGACGTATTACGCCGATCTCGACGTCTCTGCCATCGACGAGTTGCCGCCCGGCCGCACGCCC
ATCGTGACGCGCCTGGTCAACGATGCGCGGCGCGACGAAGTGATTGAACGCATCTACGCCGCAGCACGCGAAGGGCGACA
GGTCTACTGGGTTTGCCCGCTGATCGAGGAAAGCGAAGCGCTGCAATTGCAGACCGCCGTTGAAACCTTCGAGACGCTTT
CGCAAAGTCTGCAAGGCCTGAAGGTGGGCCTCGTGCATGGACGCCTGCCATCGGCCGAGAAGGCCGCCGTGATGAGCGCC
TTCGCCGGCGGCGACCTGCACGTGCTGGTGGCCACCACCGTCATCGAAGTGGGCGTGGACGTGCCCAATGCCTCATTGAT
GGTGATCGAGCACGCCGAGCGCTTTGGCCTTGCGCAACTGCATCAACTGCGCGGGCGGGTGGGGCGCGGCACGGCGGAAT
CGGTCTGCGTGCTGCTGTATCAGGCGCCACTGTCCCCGACGGCCAAGCAACGCCTGCAGACCATGCGCGAGACCACCGAC
GGTTTCGAAATCGCCCGGCGCGATCTGGAGATCCGCGGCCCTGGCGAGTTCCTGGGGGCGAGGCAATCGGGCGAAGCGAT
GCTGCGCTTTGCCGACCTGAACCAAGATGCGTGGCTCGTCGAGTTTGCGCAGGGCACCGCGGACGAGATGCTCGCGCGCT
TTCCTGAAGCCGTCGACACCCATCTCAAGCGCTGGCTGGGCGAGCGCGAGCACTACCTGCGTGTTTAA

Upstream 100 bases:

>100_bases
TGATGGTCGCGGGCGCCGGTACAATCGGGCGACTCGCAAAGTTCGCCATTGTAAACGTCCTGTGCCGTCTCGCGCCCGTT
CCGCCACTGATGCTGCTCCT

Downstream 100 bases:

>100_bases
GGGCTGAGGCGCACGCTTCGGTACGCCAGCTGTGCCTGCTTGCGCAAGCGCTTGACCGTGTCCATCGCACGATCGGCCTG
CTTGAGCGGGGCGGCGATCT

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 715; Mature: 714

Protein sequence:

>715_residues
MPDADTAPAPKPKRAATADKPAKATAKTARPADKLAKLGLHRDVDLVLHLPMRYEDETTLLTIAEATARANTGWAAQVEG
TVTRNEVAFRPRRQLVVHIADDSGELVLRFLNFYGSQVKQMAEGVRLRVRGEVRGGFFGAEMVHPTVRAVADDEPLPDRL
TPVYPSTAGVAQAYLRKAILNALTRTPLPETLPNSLVTGPLAPLKLMTPADAVRLLHQPMPDVDEHSLVERTHPAWLRIK
FDELLSQQLSLKRAQAARRMRNAPILRDSGKDGLLARFMDALPFKLTGAQARVWEEIRADLAHPYPMQRLLQGDVGSGKT
VIAALAACQAIDAGWQAALMAPTELLAEQHYRKLSAWLEPLGVDIVWLAGSLKRKQKDEAAARVAAGTAQLVIGTHALIQ
DAVTFARLGLAVVDEQHRFGVAQRLALRGKASNGDGPAANVQVPHQLMMSATPIPRTLAMTYYADLDVSAIDELPPGRTP
IVTRLVNDARRDEVIERIYAAAREGRQVYWVCPLIEESEALQLQTAVETFETLSQSLQGLKVGLVHGRLPSAEKAAVMSA
FAGGDLHVLVATTVIEVGVDVPNASLMVIEHAERFGLAQLHQLRGRVGRGTAESVCVLLYQAPLSPTAKQRLQTMRETTD
GFEIARRDLEIRGPGEFLGARQSGEAMLRFADLNQDAWLVEFAQGTADEMLARFPEAVDTHLKRWLGEREHYLRV

Sequences:

>Translated_715_residues
MPDADTAPAPKPKRAATADKPAKATAKTARPADKLAKLGLHRDVDLVLHLPMRYEDETTLLTIAEATARANTGWAAQVEG
TVTRNEVAFRPRRQLVVHIADDSGELVLRFLNFYGSQVKQMAEGVRLRVRGEVRGGFFGAEMVHPTVRAVADDEPLPDRL
TPVYPSTAGVAQAYLRKAILNALTRTPLPETLPNSLVTGPLAPLKLMTPADAVRLLHQPMPDVDEHSLVERTHPAWLRIK
FDELLSQQLSLKRAQAARRMRNAPILRDSGKDGLLARFMDALPFKLTGAQARVWEEIRADLAHPYPMQRLLQGDVGSGKT
VIAALAACQAIDAGWQAALMAPTELLAEQHYRKLSAWLEPLGVDIVWLAGSLKRKQKDEAAARVAAGTAQLVIGTHALIQ
DAVTFARLGLAVVDEQHRFGVAQRLALRGKASNGDGPAANVQVPHQLMMSATPIPRTLAMTYYADLDVSAIDELPPGRTP
IVTRLVNDARRDEVIERIYAAAREGRQVYWVCPLIEESEALQLQTAVETFETLSQSLQGLKVGLVHGRLPSAEKAAVMSA
FAGGDLHVLVATTVIEVGVDVPNASLMVIEHAERFGLAQLHQLRGRVGRGTAESVCVLLYQAPLSPTAKQRLQTMRETTD
GFEIARRDLEIRGPGEFLGARQSGEAMLRFADLNQDAWLVEFAQGTADEMLARFPEAVDTHLKRWLGEREHYLRV
>Mature_714_residues
PDADTAPAPKPKRAATADKPAKATAKTARPADKLAKLGLHRDVDLVLHLPMRYEDETTLLTIAEATARANTGWAAQVEGT
VTRNEVAFRPRRQLVVHIADDSGELVLRFLNFYGSQVKQMAEGVRLRVRGEVRGGFFGAEMVHPTVRAVADDEPLPDRLT
PVYPSTAGVAQAYLRKAILNALTRTPLPETLPNSLVTGPLAPLKLMTPADAVRLLHQPMPDVDEHSLVERTHPAWLRIKF
DELLSQQLSLKRAQAARRMRNAPILRDSGKDGLLARFMDALPFKLTGAQARVWEEIRADLAHPYPMQRLLQGDVGSGKTV
IAALAACQAIDAGWQAALMAPTELLAEQHYRKLSAWLEPLGVDIVWLAGSLKRKQKDEAAARVAAGTAQLVIGTHALIQD
AVTFARLGLAVVDEQHRFGVAQRLALRGKASNGDGPAANVQVPHQLMMSATPIPRTLAMTYYADLDVSAIDELPPGRTPI
VTRLVNDARRDEVIERIYAAAREGRQVYWVCPLIEESEALQLQTAVETFETLSQSLQGLKVGLVHGRLPSAEKAAVMSAF
AGGDLHVLVATTVIEVGVDVPNASLMVIEHAERFGLAQLHQLRGRVGRGTAESVCVLLYQAPLSPTAKQRLQTMRETTDG
FEIARRDLEIRGPGEFLGARQSGEAMLRFADLNQDAWLVEFAQGTADEMLARFPEAVDTHLKRWLGEREHYLRV

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=688, Percent_Identity=50.8720930232558, Blast_Score=616, Evalue=1e-177,
Organism=Escherichia coli, GI1787357, Length=392, Percent_Identity=38.265306122449, Blast_Score=235, Evalue=9e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 78360; Mature: 78229

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDADTAPAPKPKRAATADKPAKATAKTARPADKLAKLGLHRDVDLVLHLPMRYEDETTL
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHCCCCCCEEEEECCCCCCCCCEE
LTIAEATARANTGWAAQVEGTVTRNEVAFRPRRQLVVHIADDSGELVLRFLNFYGSQVKQ
EEEEHHHHCCCCCCEEEEECCEECCHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHH
MAEGVRLRVRGEVRGGFFGAEMVHPTVRAVADDEPLPDRLTPVYPSTAGVAQAYLRKAIL
HHCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
NALTRTPLPETLPNSLVTGPLAPLKLMTPADAVRLLHQPMPDVDEHSLVERTHPAWLRIK
HHHHCCCCCHHCCCHHHCCCCCCEEECCHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEE
FDELLSQQLSLKRAQAARRMRNAPILRDSGKDGLLARFMDALPFKLTGAQARVWEEIRAD
HHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHCCCEECCHHHHHHHHHHHH
LAHPYPMQRLLQGDVGSGKTVIAALAACQAIDAGWQAALMAPTELLAEQHYRKLSAWLEP
CCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHH
LGVDIVWLAGSLKRKQKDEAAARVAAGTAQLVIGTHALIQDAVTFARLGLAVVDEQHRFG
HCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
VAQRLALRGKASNGDGPAANVQVPHQLMMSATPIPRTLAMTYYADLDVSAIDELPPGRTP
HHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHEEEEEECCCHHHHHCCCCCCCH
IVTRLVNDARRDEVIERIYAAAREGRQVYWVCPLIEESEALQLQTAVETFETLSQSLQGL
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCE
KVGLVHGRLPSAEKAAVMSAFAGGDLHVLVATTVIEVGVDVPNASLMVIEHAERFGLAQL
EEEEEECCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCCEEEEECHHHCCHHHH
HQLRGRVGRGTAESVCVLLYQAPLSPTAKQRLQTMRETTDGFEIARRDLEIRGPGEFLGA
HHHHHHCCCCCHHHHEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHCCEECCCHHHHCC
RQSGEAMLRFADLNQDAWLVEFAQGTADEMLARFPEAVDTHLKRWLGEREHYLRV
CCCCCEEEEEECCCCCCEEEEECCCCHHHHHHHCHHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure 
PDADTAPAPKPKRAATADKPAKATAKTARPADKLAKLGLHRDVDLVLHLPMRYEDETTL
CCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHCCCCCCEEEEECCCCCCCCCEE
LTIAEATARANTGWAAQVEGTVTRNEVAFRPRRQLVVHIADDSGELVLRFLNFYGSQVKQ
EEEEHHHHCCCCCCEEEEECCEECCHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHH
MAEGVRLRVRGEVRGGFFGAEMVHPTVRAVADDEPLPDRLTPVYPSTAGVAQAYLRKAIL
HHCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
NALTRTPLPETLPNSLVTGPLAPLKLMTPADAVRLLHQPMPDVDEHSLVERTHPAWLRIK
HHHHCCCCCHHCCCHHHCCCCCCEEECCHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEE
FDELLSQQLSLKRAQAARRMRNAPILRDSGKDGLLARFMDALPFKLTGAQARVWEEIRAD
HHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHCCCEECCHHHHHHHHHHHH
LAHPYPMQRLLQGDVGSGKTVIAALAACQAIDAGWQAALMAPTELLAEQHYRKLSAWLEP
CCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHH
LGVDIVWLAGSLKRKQKDEAAARVAAGTAQLVIGTHALIQDAVTFARLGLAVVDEQHRFG
HCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
VAQRLALRGKASNGDGPAANVQVPHQLMMSATPIPRTLAMTYYADLDVSAIDELPPGRTP
HHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHEEEEEECCCHHHHHCCCCCCCH
IVTRLVNDARRDEVIERIYAAAREGRQVYWVCPLIEESEALQLQTAVETFETLSQSLQGL
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCE
KVGLVHGRLPSAEKAAVMSAFAGGDLHVLVATTVIEVGVDVPNASLMVIEHAERFGLAQL
EEEEEECCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCCEEEEECHHHCCHHHH
HQLRGRVGRGTAESVCVLLYQAPLSPTAKQRLQTMRETTDGFEIARRDLEIRGPGEFLGA
HHHHHHCCCCCHHHHEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHCCEECCCHHHHCC
RQSGEAMLRFADLNQDAWLVEFAQGTADEMLARFPEAVDTHLKRWLGEREHYLRV
CCCCCEEEEEECCCCCCEEEEECCCCHHHHHHHCHHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]