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The map label for this gene is intZ [H]

Identifier: 187929362

GI number: 187929362

Start: 2403290

End: 2404543

Strand: Direct

Name: intZ [H]

Synonym: Rpic_2283

Alternate gene names: 187929362

Gene position: 2403290-2404543 (Clockwise)

Preceding gene: 187929361

Following gene: 187929366

Centisome position: 60.96

GC content: 63.48

Gene sequence:

>1254_bases
ATGGCGGCACGGCAACTGCATCGGCTGACGGCGCTCAAGATCGGCAAGCTGGACGCGCCGGGGCAATATCCGGATGGCGG
TAACCTCCATTTCCAGATTTCTGCCACTGGCTCGCGCTCCTGGATCTTCAAGTTCACCCTGCGCGGCCGATCGCGAGAAA
TGGGGTTAGGCCCCCTTTCCTCGGTCTCACTGGCAGCTGCCCGCGCCGAAGCCGCGAAATGTCGTGACCTACTTCGGGAG
GGAATCGACCCGATCGAAGCTCGGAACGCTGAGCAGAGGAAGCGCGCCCTCGAAACATCCGGGCCGCGCCTGTTCCGTGT
GGCCTCGGCTGACTACATCTCCCAACACCGCGCCGGCTGGAAGAACGCGAAACACGCTCAGCAGTGGGAAAACACGCTGG
CGACATACGCCAACCCGATACTCGGCGATCAGGACGTGCGCGACGTAGACACCGCCATGATCGTGCGCGTGCTGCAGCCG
ATCTGGATCTCGAAGCGGGAAACCGCGTTCCGGCTGCGCGGCCGGCTGGAATGCATCCTTGACGCCGAAAAGGCTCTCGG
GCACCGGGAAGGCGAGAATCCGGCGCGCTGGCGCGGCCATCTCGACAAGCTGCTGCCGAAGCAGAATCGCCGCAAGAAGA
TCAAGCACCACCCGGCGCTGCCGTGGCAGGAGCTGCCGGAATTCATGAGGGAACTGCGCGCCGTGGCGGATTCAACCGCC
CGCATGCTGGAGCACCTGATCCTGACAGCAGTGCGCACGCAGGAAGTACTGTATGCGCGCCCAGAAGAGTTTGCGATGGA
CTATCGCGTCTGGACGGTGCCAGGCGAGCGGATGAAGATGGAGCTGCCGCTCCGCGTGCCGATGGCTGACCGCCTAGTCG
AACTGGTCACAGAGGCGATGAAGGGCGCGCGCGACGGCTGGCTGTACCCGGGCCGTAAGAAAGGGAAGCCGTATTCGAAC
ATGGCCATGCTGAAGGTGCTCGAGCGCATGGGATATGGCCACATCACCGTGCACGGATTCCGCTCGACCTTCCGGGACTG
GGTGGCAGAATGCACCGAATATGCCGACTCGCTTGCCGAAAAGGCCCTAGCCCACGCCATCCAGAACGAGAGCGAGGCGG
CTTACCGCCGTGGTGACATGCTGGAGCGCCGCCGAAAGATGATGAGCGACTGGGCCAGATTCTGCTCCGGAGAGAGGGCG
GCAATCATTTCTATCAGCCCGATGGGCAACGCGCCACTATCGGCGCACGGCTGA

Upstream 100 bases:

>100_bases
CAAGCAGTAGCAAGGTTTTGGGGGTATTTCTCTTCTTGCCGGTTCCAGACCACTCCGACACAATCCACCCATCGAACAGG
GGTGAGAACGGGGGTTGGAA

Downstream 100 bases:

>100_bases
TTAATCGGGAACCGTCGCATTCGCCCCATCGTCTGGATTAATCGACCGCGCGCAATGACCAGGTGGTCGACCGAATATTC
CGATAACCCAGTCGATGACT

Product: integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MAARQLHRLTALKIGKLDAPGQYPDGGNLHFQISATGSRSWIFKFTLRGRSREMGLGPLSSVSLAAARAEAAKCRDLLRE
GIDPIEARNAEQRKRALETSGPRLFRVASADYISQHRAGWKNAKHAQQWENTLATYANPILGDQDVRDVDTAMIVRVLQP
IWISKRETAFRLRGRLECILDAEKALGHREGENPARWRGHLDKLLPKQNRRKKIKHHPALPWQELPEFMRELRAVADSTA
RMLEHLILTAVRTQEVLYARPEEFAMDYRVWTVPGERMKMELPLRVPMADRLVELVTEAMKGARDGWLYPGRKKGKPYSN
MAMLKVLERMGYGHITVHGFRSTFRDWVAECTEYADSLAEKALAHAIQNESEAAYRRGDMLERRRKMMSDWARFCSGERA
AIISISPMGNAPLSAHG

Sequences:

>Translated_417_residues
MAARQLHRLTALKIGKLDAPGQYPDGGNLHFQISATGSRSWIFKFTLRGRSREMGLGPLSSVSLAAARAEAAKCRDLLRE
GIDPIEARNAEQRKRALETSGPRLFRVASADYISQHRAGWKNAKHAQQWENTLATYANPILGDQDVRDVDTAMIVRVLQP
IWISKRETAFRLRGRLECILDAEKALGHREGENPARWRGHLDKLLPKQNRRKKIKHHPALPWQELPEFMRELRAVADSTA
RMLEHLILTAVRTQEVLYARPEEFAMDYRVWTVPGERMKMELPLRVPMADRLVELVTEAMKGARDGWLYPGRKKGKPYSN
MAMLKVLERMGYGHITVHGFRSTFRDWVAECTEYADSLAEKALAHAIQNESEAAYRRGDMLERRRKMMSDWARFCSGERA
AIISISPMGNAPLSAHG
>Mature_416_residues
AARQLHRLTALKIGKLDAPGQYPDGGNLHFQISATGSRSWIFKFTLRGRSREMGLGPLSSVSLAAARAEAAKCRDLLREG
IDPIEARNAEQRKRALETSGPRLFRVASADYISQHRAGWKNAKHAQQWENTLATYANPILGDQDVRDVDTAMIVRVLQPI
WISKRETAFRLRGRLECILDAEKALGHREGENPARWRGHLDKLLPKQNRRKKIKHHPALPWQELPEFMRELRAVADSTAR
MLEHLILTAVRTQEVLYARPEEFAMDYRVWTVPGERMKMELPLRVPMADRLVELVTEAMKGARDGWLYPGRKKGKPYSNM
AMLKVLERMGYGHITVHGFRSTFRDWVAECTEYADSLAEKALAHAIQNESEAAYRRGDMLERRRKMMSDWARFCSGERAA
IISISPMGNAPLSAHG

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=380, Percent_Identity=29.4736842105263, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1788974, Length=410, Percent_Identity=27.8048780487805, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788690, Length=390, Percent_Identity=25.3846153846154, Blast_Score=108, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 47468; Mature: 47337

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARQLHRLTALKIGKLDAPGQYPDGGNLHFQISATGSRSWIFKFTLRGRSREMGLGPLS
CCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCCCCH
SVSLAAARAEAAKCRDLLREGIDPIEARNAEQRKRALETSGPRLFRVASADYISQHRAGW
HHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCC
KNAKHAQQWENTLATYANPILGDQDVRDVDTAMIVRVLQPIWISKRETAFRLRGRLECIL
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEE
DAEKALGHREGENPARWRGHLDKLLPKQNRRKKIKHHPALPWQELPEFMRELRAVADSTA
EHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
RMLEHLILTAVRTQEVLYARPEEFAMDYRVWTVPGERMKMELPLRVPMADRLVELVTEAM
HHHHHHHHHHHHHHHHHHCCCHHHHCCEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHH
KGARDGWLYPGRKKGKPYSNMAMLKVLERMGYGHITVHGFRSTFRDWVAECTEYADSLAE
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
KALAHAIQNESEAAYRRGDMLERRRKMMSDWARFCSGERAAIISISPMGNAPLSAHG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
AARQLHRLTALKIGKLDAPGQYPDGGNLHFQISATGSRSWIFKFTLRGRSREMGLGPLS
CHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCCCCH
SVSLAAARAEAAKCRDLLREGIDPIEARNAEQRKRALETSGPRLFRVASADYISQHRAGW
HHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCC
KNAKHAQQWENTLATYANPILGDQDVRDVDTAMIVRVLQPIWISKRETAFRLRGRLECIL
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEE
DAEKALGHREGENPARWRGHLDKLLPKQNRRKKIKHHPALPWQELPEFMRELRAVADSTA
EHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
RMLEHLILTAVRTQEVLYARPEEFAMDYRVWTVPGERMKMELPLRVPMADRLVELVTEAM
HHHHHHHHHHHHHHHHHHCCCHHHHCCEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHH
KGARDGWLYPGRKKGKPYSNMAMLKVLERMGYGHITVHGFRSTFRDWVAECTEYADSLAE
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
KALAHAIQNESEAAYRRGDMLERRRKMMSDWARFCSGERAAIISISPMGNAPLSAHG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]