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The map label for this gene is dnaJ [H]

Identifier: 187929366

GI number: 187929366

Start: 2408197

End: 2408574

Strand: Direct

Name: dnaJ [H]

Synonym: Rpic_2287

Alternate gene names: 187929366

Gene position: 2408197-2408574 (Clockwise)

Preceding gene: 187929362

Following gene: 187929409

Centisome position: 61.08

GC content: 56.61

Gene sequence:

>378_bases
ATGGACTGCAGTTATTACGAGGTCCTGATGGTGACGCGCGACGCGTCTCCGGAGGTCATCAGAGCGGCATACAAAGCGCT
GTCGCAGAAATGGCATCCGGACCGCAACGAACATCCGGATGCCCCGCAAATCATGACGTTGCTCAACCAGGCGTACGAGG
AACTCTCCGACCCTGATAGGCGGCTTGCATACGATGCTTGGATTGCCGCCGGATGCCCCGCGGACCCGATTCCGGAACCG
CCCAAGTCTCAGGCTTTCGATGTTGATGAAGAAAAGCTGCGCGAAGGCCTTGCAGTCCTCGAGGCCCGCAAAAAGAAATA
CCCAAAATTCGGAAAAATGATGATCTGGGCGCTCATCGTGAGCGCCATCACTTCGTGA

Upstream 100 bases:

>100_bases
CGTTCGGCAGAAGTTGTGGCATGGGGCCTCAAAACAAAAAGGCCACCCGGAGGTAGCCTAAAATGAGAAAACCCCGCACT
TGGCGGGGTTGGAGGGTTCA

Downstream 100 bases:

>100_bases
CCGGTTTCGGGTTGCCCATTAGTGCGCGCAGCTTGTTTGCATTGGCTGCATCAATCCTCGTGGCCATCTTCGTGGCTGCA
GAAGAACCAAAGGTTGAACC

Product: heat shock protein DnaJ domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MDCSYYEVLMVTRDASPEVIRAAYKALSQKWHPDRNEHPDAPQIMTLLNQAYEELSDPDRRLAYDAWIAAGCPADPIPEP
PKSQAFDVDEEKLREGLAVLEARKKKYPKFGKMMIWALIVSAITS

Sequences:

>Translated_125_residues
MDCSYYEVLMVTRDASPEVIRAAYKALSQKWHPDRNEHPDAPQIMTLLNQAYEELSDPDRRLAYDAWIAAGCPADPIPEP
PKSQAFDVDEEKLREGLAVLEARKKKYPKFGKMMIWALIVSAITS
>Mature_125_residues
MDCSYYEVLMVTRDASPEVIRAAYKALSQKWHPDRNEHPDAPQIMTLLNQAYEELSDPDRRLAYDAWIAAGCPADPIPEP
PKSQAFDVDEEKLREGLAVLEARKKKYPKFGKMMIWALIVSAITS

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG2214

COG function: function code O; DnaJ-class molecular chaperone

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI23503241, Length=107, Percent_Identity=37.3831775700935, Blast_Score=66, Evalue=6e-12,
Organism=Homo sapiens, GI22749377, Length=64, Percent_Identity=45.3125, Blast_Score=65, Evalue=1e-11,
Organism=Homo sapiens, GI194328760, Length=64, Percent_Identity=48.4375, Blast_Score=65, Evalue=2e-11,
Organism=Homo sapiens, GI194328758, Length=64, Percent_Identity=48.4375, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323813, Length=61, Percent_Identity=42.6229508196721, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]

EC number: NA

Molecular weight: Translated: 14224; Mature: 14224

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDCSYYEVLMVTRDASPEVIRAAYKALSQKWHPDRNEHPDAPQIMTLLNQAYEELSDPDR
CCCCCEEHEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHH
RLAYDAWIAAGCPADPIPEPPKSQAFDVDEEKLREGLAVLEARKKKYPKFGKMMIWALIV
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
SAITS
HHHCC
>Mature Secondary Structure
MDCSYYEVLMVTRDASPEVIRAAYKALSQKWHPDRNEHPDAPQIMTLLNQAYEELSDPDR
CCCCCEEHEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHH
RLAYDAWIAAGCPADPIPEPPKSQAFDVDEEKLREGLAVLEARKKKYPKFGKMMIWALIV
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
SAITS
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12466555 [H]