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The map label for this gene is blh [H]

Identifier: 187929092

GI number: 187929092

Start: 2118626

End: 2119486

Strand: Reverse

Name: blh [H]

Synonym: Rpic_2013

Alternate gene names: 187929092

Gene position: 2119486-2118626 (Counterclockwise)

Preceding gene: 187929097

Following gene: 187929090

Centisome position: 53.76

GC content: 64.92

Gene sequence:

>861_bases
ATGCACGCCCAGATCGAATCCTTCTTCGACCCCGATACCTGCACCATGACCTACGTCGTGCACGCGGGGCCCGGCTCGCC
CTGTGCCGTGATCGATTCGGTACTCGACTACGACCCCAAATCGGGCCGCACGACGACCCGCTCGGCCGACCGCGTTGCGG
CGTTCATCGAAGCGCAGGACTTGCGCATCGAATGGCTACTGGAGACCCACGCGCATGCCGATCACCTGTCGGCTGCGCCG
TGTCTGCGTGGGCGTTACGGCGGGCGTATCGCCATCGGTGAGCGCATTCGCGTCGTGCAGGGCGTGTTCAAGCCGATCTT
CAACCTCGAGCCCGCGTTCCAGCTCGATGGCTCCCAGTTTGACCATCTGTTTGCGCCGGACGAGGTGTTCCATATCGGCA
ATCTGGAAGCAAAGGCACTGGCCGTGCCGGGCCACACGCCGGCAGACATGGCGTATCAGGTGGGCGATGCGGTGTTTGTG
GGCGACACGCTGTTCATGCCGGACGTGGGCACCGCGCGCTGCGATTTTCCGGGAGGGAATGCGGGCACGCTGTACCAGTC
GATCCGCCGCTTGCTGGATCTGCCGCCGGACACGCGCCTCTACATGTGCCACGACTATCCGCCCGGTGGGCGCGAAGCCG
TGTGCCACACAACGGTGGCCGAGCAGCGCCGCGCCAACATCCATGTGCGCGATGGCGTGACCGAGGCCGAGTTCGTGCAG
ATGCGCACGAAGCGCGATGCCACGCTCGGCATGCCGACGCTGATGCTGCCGGCCATTCAGGTGAACATTCGCGCGGGCAT
GTTGCCTCCGGCCGAGCCAAACGGCGTGCAGTACCTCAAGATTCCTCTGAACGCGCTGTAA

Upstream 100 bases:

>100_bases
GGGGCGTGGTGCGAGGGTTTATTCATGCTGTTTGCGCTATTGGCAGACAGAATGTCAGACGATATTCTATAAAAATATAG
ATTGTTCGGGAAAGTCCACC

Downstream 100 bases:

>100_bases
CGGCTCAGGGAGCGAGCAGCGCGGCACGCGCAGCAGTCAGCACTTGGCGGCTGAGTTCATCGAGCAGCGCCGAGGCCGCC
CGCGCATGCTGCCAATACAG

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MHAQIESFFDPDTCTMTYVVHAGPGSPCAVIDSVLDYDPKSGRTTTRSADRVAAFIEAQDLRIEWLLETHAHADHLSAAP
CLRGRYGGRIAIGERIRVVQGVFKPIFNLEPAFQLDGSQFDHLFAPDEVFHIGNLEAKALAVPGHTPADMAYQVGDAVFV
GDTLFMPDVGTARCDFPGGNAGTLYQSIRRLLDLPPDTRLYMCHDYPPGGREAVCHTTVAEQRRANIHVRDGVTEAEFVQ
MRTKRDATLGMPTLMLPAIQVNIRAGMLPPAEPNGVQYLKIPLNAL

Sequences:

>Translated_286_residues
MHAQIESFFDPDTCTMTYVVHAGPGSPCAVIDSVLDYDPKSGRTTTRSADRVAAFIEAQDLRIEWLLETHAHADHLSAAP
CLRGRYGGRIAIGERIRVVQGVFKPIFNLEPAFQLDGSQFDHLFAPDEVFHIGNLEAKALAVPGHTPADMAYQVGDAVFV
GDTLFMPDVGTARCDFPGGNAGTLYQSIRRLLDLPPDTRLYMCHDYPPGGREAVCHTTVAEQRRANIHVRDGVTEAEFVQ
MRTKRDATLGMPTLMLPAIQVNIRAGMLPPAEPNGVQYLKIPLNAL
>Mature_286_residues
MHAQIESFFDPDTCTMTYVVHAGPGSPCAVIDSVLDYDPKSGRTTTRSADRVAAFIEAQDLRIEWLLETHAHADHLSAAP
CLRGRYGGRIAIGERIRVVQGVFKPIFNLEPAFQLDGSQFDHLFAPDEVFHIGNLEAKALAVPGHTPADMAYQVGDAVFV
GDTLFMPDVGTARCDFPGGNAGTLYQSIRRLLDLPPDTRLYMCHDYPPGGREAVCHTTVAEQRRANIHVRDGVTEAEFVQ
MRTKRDATLGMPTLMLPAIQVNIRAGMLPPAEPNGVQYLKIPLNAL

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=269, Percent_Identity=27.8810408921933, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17538952, Length=257, Percent_Identity=24.5136186770428, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI221330176, Length=237, Percent_Identity=25.7383966244726, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 31350; Mature: 31350

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAQIESFFDPDTCTMTYVVHAGPGSPCAVIDSVLDYDPKSGRTTTRSADRVAAFIEAQD
CCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHEEEEECCC
LRIEWLLETHAHADHLSAAPCLRGRYGGRIAIGERIRVVQGVFKPIFNLEPAFQLDGSQF
CEEEEEEECCCCCCCCCCCCHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCEEECCCCC
DHLFAPDEVFHIGNLEAKALAVPGHTPADMAYQVGDAVFVGDTLFMPDVGTARCDFPGGN
CCCCCCCCEEEECCCCEEEEECCCCCCHHHHHHCCCEEEECCEEECCCCCCCEECCCCCC
AGTLYQSIRRLLDLPPDTRLYMCHDYPPGGREAVCHTTVAEQRRANIHVRDGVTEAEFVQ
HHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEHHHHHHHHCEEEEECCCCHHHHHH
MRTKRDATLGMPTLMLPAIQVNIRAGMLPPAEPNGVQYLKIPLNAL
HHHHCCCCCCCCHHEEEEEEEEEEECCCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MHAQIESFFDPDTCTMTYVVHAGPGSPCAVIDSVLDYDPKSGRTTTRSADRVAAFIEAQD
CCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHEEEEECCC
LRIEWLLETHAHADHLSAAPCLRGRYGGRIAIGERIRVVQGVFKPIFNLEPAFQLDGSQF
CEEEEEEECCCCCCCCCCCCHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCEEECCCCC
DHLFAPDEVFHIGNLEAKALAVPGHTPADMAYQVGDAVFVGDTLFMPDVGTARCDFPGGN
CCCCCCCCEEEECCCCEEEEECCCCCCHHHHHHCCCEEEECCEEECCCCCCCEECCCCCC
AGTLYQSIRRLLDLPPDTRLYMCHDYPPGGREAVCHTTVAEQRRANIHVRDGVTEAEFVQ
HHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEHHHHHHHHCEEEEECCCCHHHHHH
MRTKRDATLGMPTLMLPAIQVNIRAGMLPPAEPNGVQYLKIPLNAL
HHHHCCCCCCCCHHEEEEEEEEEEECCCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]