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The map label for this gene is aceE [H]

Identifier: 187929027

GI number: 187929027

Start: 2054186

End: 2056876

Strand: Reverse

Name: aceE [H]

Synonym: Rpic_1947

Alternate gene names: 187929027

Gene position: 2056876-2054186 (Counterclockwise)

Preceding gene: 187929034

Following gene: 187929026

Centisome position: 52.17

GC content: 62.13

Gene sequence:

>2691_bases
ATGTCGGCCGTACCAGAACAAGTCCTGGGTGCCACGAGCGCCAGCGACGTTGATCCCCAGGAAACCAAGGAATGGCTGGA
GGCGCTGCAAGGCGTCATCGGCGCGGAAGGCCCGCAGCGCGCGGCATTCCTCCTCGACAAGCAGATCGAGTACGCGCGCA
TCAACGGCGTGACGTCTCCGCTGCACGCAGAAACCCCCTATATCAATACGATCCCGGTCGAGAACCAGGACCGCATTCCT
GGCAACCAGGAAATCGAGCATCGCATCCGTTCGTATACGCGCTGGAACGCCATGGCGATGGTGCTGCGCGCGAACAAGGA
CACCAACGTCGGCGGGCATATCTCGTCGTTCGCTTCGGCGGCCACGCTGTATGACGTCGGCTACAACCACTTCTGGCACG
CCCCGTCGGACAAGCACGGCGGCGACATGGTTTTCGTGCAGGGGCACTCGGCGCCGGGCGTGTACTCGCGCGCATTCCTG
CTGGGCCGTCTAAGCGAGGAGCAACTCGACAGCTTCCGCCAGGAAGTCGACGGCAAGGGCATCTCGTCGTACCCGCACCC
GTGGCTGATGCCGGATTTCTGGCAATTCCCGACCGTGTCGATGGGCCTGGGCCCGATCATGGCGATCTACCAGGCGCGCT
TTACCAAGTACCTGGCCAGCCGCGGCCTGATCCAGAACTGGGAAAACCGCAAGGTCTGGGCGTTCCTGGGCGACGGCGAA
ACCGACGAGCCGGAATCGCTGGGAGCGATTGGCATGGCCGGCCGTGAAAAGCTGGACAACCTCGTCTTCGTGATCAACTG
CAACCTGCAGCGCCTGGATGGTCCGGTGCGCGGCAACGGCAAGATCATCCAGGAGCTGGAATCGGAATTCCGCGGCGCAG
GCTGGAACGTCATCAAGGTCATCTGGGGCAGCCGCTGGGATCAGCTGCTTGCCCGCGACACGAAGGGCCTGCTGATGAGC
CGCATGATGGAATGCGTCGACGGCGAGTACCAGACCTTCAAATCGAAGAGCGGCGCTTATGTGCGCGAGTTCTTCTTCAA
CACGCCGGAACTCAAGGCCATGGTGGCCGATTGGTCCGACGACGACATCTGGGCGCTGAACCGTGGCGGCCATGATCCGC
ACAAGATCTACGCGGCATTCCAGTCGGCGACCAACCACAAGGGTCAGCCGACCGTCATTCTCGCCAAGACCATCAAGGGC
TATGGCATGGGTGAGGCCGGCGAAGCGATGAACATCGCCCACCAGCAGAAGAAGATGCCGGTGGACGCCATCCGCAAGCT
GCGTGATCGCTTCAACATTCCGGTTGCCGACGACCAGCTCGAGCACGTGCCGTACGTCAAGTTCGAAGAAGGCTCGAAGG
AACTCGAATACATGCGCAAGGCCCGTATGGACCTGGGCGGCTACCTGCCGGCCCGTCGCCAGAAGGCCGACGCGCTGCAG
ATTCCCGCGCTGGCTGCGTTCGACGCGTTGCTCAAAGCCACCGGTGAAGGCCGCGAAGTGTCCACGACGATGGCCTTTGT
GCGCATTCTGAACATCCTGCTGAAGGACAAGAACATCGGTAAGCATGTTGTGCCCATCGTGCCCGATGAGTCGCGTACGT
TCGGCATGGAAGGTCTGTTCCGCCAGGTGGGTATCTGGAACCAGGAAGGCCAGAAGTACGTGCCGCAGGATCACGACCAA
CTGATGTTCTACAAGGAATCGCAGACGGGTCAGGTGCTGCAGGAAGGCATCAACGAAGCCGGTGCCATGTGCGACTGGAT
CGCGGCCGCTACGTCGTATTCGACGCATGGCGTGGCGATGATCCCGTTCTACATCTACTACTCGATGTTCGGCATCCAGC
GTATCGGCGACCTCTGCTGGGCCGCCGGCGACATGCGCTCGCGCGGCTTCCTGCTGGGCGGCACAGCTGGCCGTACCACG
CTGAACGGCGAAGGCCTGCAGCACGAAGACGGCCACTCGCACGTGTACCACGCTGCCATCCCGAACTGCATCTCGTATGA
CCCGACCTTCCAGTACGAACTGGCGGTGGTGATGCAAGACGGCCTGCGTCGCATGTATGTCGAGCAGGAAGACGTCTATT
ACTACCTGACGGTGATGAACGAAAACTACGAGCACCCGGAAATGCCGGCGGGTGTCGAGGCGGACATCATCAAGGGGATG
TACCAGTTCAAGAAGGGCGTCGAAAACAGCAACGCACCGCGCGTGCAACTGCTGGGTTCGGGCACGATCTTCCGCGAGGT
GATCGCCGCCGCCGAGCTGCTCAAGAAGGACTGGGGCGTGGAATCCGACCTGTGGGGCTGCCCGAGCTTTACCGAGCTGG
CCCGTGAAGGCAACGCCATCGCGCGCTGGAACCTGCTCAACCCGACGGCACCGCAACGCGAGTCGCACGTCGAGAAGCTC
CTCAAGAACGCACGCGGTCCGGTCATCGCTTCGACCGACTACGTCCGTACTTTCGCCGAGCAGATCCGCGCCTTCGTGCC
GCGTCGCTATGTGGTGCTGGGCACCGACGGCTTCGGCCGCTCGGATACCCGCGAGAAGCTGCGTCACTTCTTCGAGGTGG
ATCGCTACTGGGTGACGGTTGCGTCGCTCAAGGCGCTCGCCGATGAAGGCGTGCTGCCGCGCGAGAAGGTGGCCGAGGCA
CTGAAGAAGTACAACCTCGATCCGAACAAGCCCAACCCGATGACCGTATAA

Upstream 100 bases:

>100_bases
GCGCAAAAGTCGGGGTGGCCCTTGCGTGCGTGTGAACGCGCGTGCCAGTGGGCGCCTCACAAGAGACGCAACTACCGTTA
CTGCTACCAAGGAGACCGCC

Downstream 100 bases:

>100_bases
CGGAGCCGCCGGGCGCGCGGGTTGCGTTCCGGCTGGGCACCGCCCTGACAGACTTTCCGCAACGTGCATTTGCCTGCACG
ATGCGGTAGCCTGCGGGCAC

Product: pyruvate dehydrogenase subunit E1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 896; Mature: 895

Protein sequence:

>896_residues
MSAVPEQVLGATSASDVDPQETKEWLEALQGVIGAEGPQRAAFLLDKQIEYARINGVTSPLHAETPYINTIPVENQDRIP
GNQEIEHRIRSYTRWNAMAMVLRANKDTNVGGHISSFASAATLYDVGYNHFWHAPSDKHGGDMVFVQGHSAPGVYSRAFL
LGRLSEEQLDSFRQEVDGKGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFTKYLASRGLIQNWENRKVWAFLGDGE
TDEPESLGAIGMAGREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDQLLARDTKGLLMS
RMMECVDGEYQTFKSKSGAYVREFFFNTPELKAMVADWSDDDIWALNRGGHDPHKIYAAFQSATNHKGQPTVILAKTIKG
YGMGEAGEAMNIAHQQKKMPVDAIRKLRDRFNIPVADDQLEHVPYVKFEEGSKELEYMRKARMDLGGYLPARRQKADALQ
IPALAAFDALLKATGEGREVSTTMAFVRILNILLKDKNIGKHVVPIVPDESRTFGMEGLFRQVGIWNQEGQKYVPQDHDQ
LMFYKESQTGQVLQEGINEAGAMCDWIAAATSYSTHGVAMIPFYIYYSMFGIQRIGDLCWAAGDMRSRGFLLGGTAGRTT
LNGEGLQHEDGHSHVYHAAIPNCISYDPTFQYELAVVMQDGLRRMYVEQEDVYYYLTVMNENYEHPEMPAGVEADIIKGM
YQFKKGVENSNAPRVQLLGSGTIFREVIAAAELLKKDWGVESDLWGCPSFTELAREGNAIARWNLLNPTAPQRESHVEKL
LKNARGPVIASTDYVRTFAEQIRAFVPRRYVVLGTDGFGRSDTREKLRHFFEVDRYWVTVASLKALADEGVLPREKVAEA
LKKYNLDPNKPNPMTV

Sequences:

>Translated_896_residues
MSAVPEQVLGATSASDVDPQETKEWLEALQGVIGAEGPQRAAFLLDKQIEYARINGVTSPLHAETPYINTIPVENQDRIP
GNQEIEHRIRSYTRWNAMAMVLRANKDTNVGGHISSFASAATLYDVGYNHFWHAPSDKHGGDMVFVQGHSAPGVYSRAFL
LGRLSEEQLDSFRQEVDGKGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFTKYLASRGLIQNWENRKVWAFLGDGE
TDEPESLGAIGMAGREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDQLLARDTKGLLMS
RMMECVDGEYQTFKSKSGAYVREFFFNTPELKAMVADWSDDDIWALNRGGHDPHKIYAAFQSATNHKGQPTVILAKTIKG
YGMGEAGEAMNIAHQQKKMPVDAIRKLRDRFNIPVADDQLEHVPYVKFEEGSKELEYMRKARMDLGGYLPARRQKADALQ
IPALAAFDALLKATGEGREVSTTMAFVRILNILLKDKNIGKHVVPIVPDESRTFGMEGLFRQVGIWNQEGQKYVPQDHDQ
LMFYKESQTGQVLQEGINEAGAMCDWIAAATSYSTHGVAMIPFYIYYSMFGIQRIGDLCWAAGDMRSRGFLLGGTAGRTT
LNGEGLQHEDGHSHVYHAAIPNCISYDPTFQYELAVVMQDGLRRMYVEQEDVYYYLTVMNENYEHPEMPAGVEADIIKGM
YQFKKGVENSNAPRVQLLGSGTIFREVIAAAELLKKDWGVESDLWGCPSFTELAREGNAIARWNLLNPTAPQRESHVEKL
LKNARGPVIASTDYVRTFAEQIRAFVPRRYVVLGTDGFGRSDTREKLRHFFEVDRYWVTVASLKALADEGVLPREKVAEA
LKKYNLDPNKPNPMTV
>Mature_895_residues
SAVPEQVLGATSASDVDPQETKEWLEALQGVIGAEGPQRAAFLLDKQIEYARINGVTSPLHAETPYINTIPVENQDRIPG
NQEIEHRIRSYTRWNAMAMVLRANKDTNVGGHISSFASAATLYDVGYNHFWHAPSDKHGGDMVFVQGHSAPGVYSRAFLL
GRLSEEQLDSFRQEVDGKGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFTKYLASRGLIQNWENRKVWAFLGDGET
DEPESLGAIGMAGREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDQLLARDTKGLLMSR
MMECVDGEYQTFKSKSGAYVREFFFNTPELKAMVADWSDDDIWALNRGGHDPHKIYAAFQSATNHKGQPTVILAKTIKGY
GMGEAGEAMNIAHQQKKMPVDAIRKLRDRFNIPVADDQLEHVPYVKFEEGSKELEYMRKARMDLGGYLPARRQKADALQI
PALAAFDALLKATGEGREVSTTMAFVRILNILLKDKNIGKHVVPIVPDESRTFGMEGLFRQVGIWNQEGQKYVPQDHDQL
MFYKESQTGQVLQEGINEAGAMCDWIAAATSYSTHGVAMIPFYIYYSMFGIQRIGDLCWAAGDMRSRGFLLGGTAGRTTL
NGEGLQHEDGHSHVYHAAIPNCISYDPTFQYELAVVMQDGLRRMYVEQEDVYYYLTVMNENYEHPEMPAGVEADIIKGMY
QFKKGVENSNAPRVQLLGSGTIFREVIAAAELLKKDWGVESDLWGCPSFTELAREGNAIARWNLLNPTAPQRESHVEKLL
KNARGPVIASTDYVRTFAEQIRAFVPRRYVVLGTDGFGRSDTREKLRHFFEVDRYWVTVASLKALADEGVLPREKVAEAL
KKYNLDPNKPNPMTV

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=885, Percent_Identity=61.2429378531073, Blast_Score=1113, Evalue=0.0,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 100703; Mature: 100571

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVPEQVLGATSASDVDPQETKEWLEALQGVIGAEGPQRAAFLLDKQIEYARINGVTSP
CCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHCCCCCC
LHAETPYINTIPVENQDRIPGNQEIEHRIRSYTRWNAMAMVLRANKDTNVGGHISSFASA
CCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHH
ATLYDVGYNHFWHAPSDKHGGDMVFVQGHSAPGVYSRAFLLGRLSEEQLDSFRQEVDGKG
HHHHHCCCCCEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCC
ISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFTKYLASRGLIQNWENRKVWAFLGDGE
CCCCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHCHHHHCCCCCEEEEEECCCC
TDEPESLGAIGMAGREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKV
CCCCHHCCCCCCCCHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEE
IWGSRWDQLLARDTKGLLMSRMMECVDGEYQTFKSKSGAYVREFFFNTPELKAMVADWSD
ECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHCCCCCCEEEEECCCC
DDIWALNRGGHDPHKIYAAFQSATNHKGQPTVILAKTIKGYGMGEAGEAMNIAHQQKKMP
CCEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCC
VDAIRKLRDRFNIPVADDQLEHVPYVKFEEGSKELEYMRKARMDLGGYLPARRQKADALQ
HHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCHHCCCCHHC
IPALAAFDALLKATGEGREVSTTMAFVRILNILLKDKNIGKHVVPIVPDESRTFGMEGLF
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHH
RQVGIWNQEGQKYVPQDHDQLMFYKESQTGQVLQEGINEAGAMCDWIAAATSYSTHGVAM
HHHCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
IPFYIYYSMFGIQRIGDLCWAAGDMRSRGFLLGGTAGRTTLNGEGLQHEDGHSHVYHAAI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEECCCCCCCCCCCCEEEECCC
PNCISYDPTFQYELAVVMQDGLRRMYVEQEDVYYYLTVMNENYEHPEMPAGVEADIIKGM
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHH
YQFKKGVENSNAPRVQLLGSGTIFREVIAAAELLKKDWGVESDLWGCPSFTELAREGNAI
HHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCE
ARWNLLNPTAPQRESHVEKLLKNARGPVIASTDYVRTFAEQIRAFVPRRYVVLGTDGFGR
EEEECCCCCCCCHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHCCCCEEEEECCCCCC
SDTREKLRHFFEVDRYWVTVASLKALADEGVLPREKVAEALKKYNLDPNKPNPMTV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SAVPEQVLGATSASDVDPQETKEWLEALQGVIGAEGPQRAAFLLDKQIEYARINGVTSP
CCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHCCCCCC
LHAETPYINTIPVENQDRIPGNQEIEHRIRSYTRWNAMAMVLRANKDTNVGGHISSFASA
CCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHH
ATLYDVGYNHFWHAPSDKHGGDMVFVQGHSAPGVYSRAFLLGRLSEEQLDSFRQEVDGKG
HHHHHCCCCCEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCC
ISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFTKYLASRGLIQNWENRKVWAFLGDGE
CCCCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHCHHHHCCCCCEEEEEECCCC
TDEPESLGAIGMAGREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKV
CCCCHHCCCCCCCCHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEE
IWGSRWDQLLARDTKGLLMSRMMECVDGEYQTFKSKSGAYVREFFFNTPELKAMVADWSD
ECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHCCCCCCEEEEECCCC
DDIWALNRGGHDPHKIYAAFQSATNHKGQPTVILAKTIKGYGMGEAGEAMNIAHQQKKMP
CCEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCC
VDAIRKLRDRFNIPVADDQLEHVPYVKFEEGSKELEYMRKARMDLGGYLPARRQKADALQ
HHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCHHCCCCHHC
IPALAAFDALLKATGEGREVSTTMAFVRILNILLKDKNIGKHVVPIVPDESRTFGMEGLF
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHH
RQVGIWNQEGQKYVPQDHDQLMFYKESQTGQVLQEGINEAGAMCDWIAAATSYSTHGVAM
HHHCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
IPFYIYYSMFGIQRIGDLCWAAGDMRSRGFLLGGTAGRTTLNGEGLQHEDGHSHVYHAAI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEECCCCCCCCCCCCEEEECCC
PNCISYDPTFQYELAVVMQDGLRRMYVEQEDVYYYLTVMNENYEHPEMPAGVEADIIKGM
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHH
YQFKKGVENSNAPRVQLLGSGTIFREVIAAAELLKKDWGVESDLWGCPSFTELAREGNAI
HHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCE
ARWNLLNPTAPQRESHVEKLLKNARGPVIASTDYVRTFAEQIRAFVPRRYVVLGTDGFGR
EEEECCCCCCCCHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHCCCCEEEEECCCCCC
SDTREKLRHFFEVDRYWVTVASLKALADEGVLPREKVAEALKKYNLDPNKPNPMTV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8021225 [H]