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The map label for this gene is phbC [H]

Identifier: 187928996

GI number: 187928996

Start: 2021179

End: 2022972

Strand: Reverse

Name: phbC [H]

Synonym: Rpic_1916

Alternate gene names: 187928996

Gene position: 2022972-2021179 (Counterclockwise)

Preceding gene: 187928998

Following gene: 187928995

Centisome position: 51.31

GC content: 62.82

Gene sequence:

>1794_bases
ATGGCATCGCGTCAATCGACATCATCCAAAGCATCTAGCGCCCACACTCAAGCTCCCTGGCCGGGCTTGTCGGACCCTAC
GCAGTGGGCAGAGCAGTTCAAGCAATGGCAAGCCTTTGCGGGCGCCTTCGCGCAACCCGGTGCGGCGGCGCCTGGTCTTG
GCCAGTTCAACGGCGCAGCGATGGGTGAGGGTGCGGCTCCGTTCGCACTGATTCCGCACGAGCGGCTGGCCGAAATCCAG
CAGAAGTATCTTGAAGAATGGCTTCAGATCTGGCGCCACATGAGCACCGGCGAAAGCGCCGAAGCCGTGGCGCCGTCGGA
TCGCCGTTTCTCGAACGATGCGTGGCGCAAGAGCCCGCTCTACGGCTACGCGGCTGCGTTCTACGTGCTCAACGCCCGCA
CGTTGATGGAAATGGCCGATGCAGTCCAGGCGGACGTCAAGACCCGCGAGCGCGTGCGCTTTGCCGTTTCGCAATGGACA
GCGGCCATGTCGCCGTCCAACTTCCTTGCGACCAACCCGGAAGCGCAGAAACAACTGATTGAGTCGCGTGGCGAATCCCT
GCGCACCGGCATCCTGAACATGCTGCAGGACATGGAGCGCGGCAAGATCTCGCAGACAGACGAAACTGCGTTCGAGATCG
GCCGCAACGTCGCCAACAGCGAAGGCGCGGTCGTTTTCGAGAACGACTACTTCCAGCTCATCCAGTACAAGCCGCTGACA
GCCAAGGTGCATGCGCGCCCGCTGCTGCTGGTGCCGCCCTGCATCAACAAGTACTATATCCTCGATCTGCAGCCGGCCAA
TTCGCTCGTCCGCTATGCGGTGGAGCAGGGCAATACCGTATTCCTGGTGTCGTGGCGCAATCCGGACGCGAGCATGGCCT
CCCGCACGTGGGACGACTACATCGAAGGTGGTGCGATCGAGGCCATTCGCGTTGCACGCGAGATCTCCGCGCAGGACCAG
ATCAACGTGCTGGGCTTTTGTGTAGGCGGTACGATCCTCTCGACAGCCCTGGCCGTGCTCGCGGAGCGCGGCGAGCACCC
GGCCGCGAGCCTGACGCTGCTGACCACGCTGCTCGACTTTACGGACACCGGCATTCTCGACGTGTTTGTCGACCAGGCCC
AGGTGGAAATGCGTGAAAAGACCATCGGCAGCAATGCGCCGACCGGCCCGGGCCTGCTGCGTGGCGTGGAGCTGGCAAAC
ACGTTCTCGTTCCTGCGCCCGAACGATCTCGTCTGGAACTACGTTGTCGAGAACTATCTGAAGGGCAAGACGCCCGCGCC
GTTCGACCTGTTGTACTGGAATGGCGATTCCACCAATCTGCCGGGCCCGTGGTACTGCTGGTACCTGCGCCATACGTACC
TGCAGAACGACCTCAAGACGCCGGGCAAGCTGAAGGTGAACGGCACGCCAGTGGATCTCGGCAAGATCGAGGCGCCGGTC
TACATCTACGGCTCGCGTGAAGACCACATCGTTCCGTGGAAGTCGGCCTATGGCTCGGTGCCGCTGCTCAAGGGCAAGCG
GCGTTTCGTCCTGGGCGCTTCGGGACATATCGCAGGCGTCATCAACCCGCCTGCGGCCAACAAGCGTTCGCACTGGATCA
ATGCCAAGCTGCCCGAGTCCGCCGATGCGTGGTTCGAGGGTGCCAAGGAGCATCCCGGCAGCTGGTGGCCGGATTGGTCA
ACTTGGCTCGCATCCCACGCCGGTGCGCAGAAAGCTGCGCCCAAGGGCTACGGCAATGCGGACTACCCGGCCATCGAGCC
GGCGCCCGGCCGCTACGTCAAACAGAAAGCGTAA

Upstream 100 bases:

>100_bases
ATTGACAGCCTTGAAACGGCAAGGCAACAATGCCTCGCAATACTACGAGTTGCGCCGCCGTTCCAACCGGAGCGGCGCAT
ATCGTCGGATCGAGGGCACT

Downstream 100 bases:

>100_bases
GATCGCGCGCATGAACCCCCGTTGCCGTCGCGGCTTCGGCCGCTGACGGTATCCAACGACCCTCTCTTTCGACAGTGGAA
GGTAAGCAAATGACCGATGT

Product: poly(R)-hydroxyalkanoic acid synthase, class I

Products: NA

Alternate protein names: PHA synthase; PHB synthase; Poly(3-hydroxyalkanoate) polymerase; PHA polymerase; Poly(3-hydroxybutyrate) polymerase; PHB polymerase; Polyhydroxyalkanoic acid synthase [H]

Number of amino acids: Translated: 597; Mature: 596

Protein sequence:

>597_residues
MASRQSTSSKASSAHTQAPWPGLSDPTQWAEQFKQWQAFAGAFAQPGAAAPGLGQFNGAAMGEGAAPFALIPHERLAEIQ
QKYLEEWLQIWRHMSTGESAEAVAPSDRRFSNDAWRKSPLYGYAAAFYVLNARTLMEMADAVQADVKTRERVRFAVSQWT
AAMSPSNFLATNPEAQKQLIESRGESLRTGILNMLQDMERGKISQTDETAFEIGRNVANSEGAVVFENDYFQLIQYKPLT
AKVHARPLLLVPPCINKYYILDLQPANSLVRYAVEQGNTVFLVSWRNPDASMASRTWDDYIEGGAIEAIRVAREISAQDQ
INVLGFCVGGTILSTALAVLAERGEHPAASLTLLTTLLDFTDTGILDVFVDQAQVEMREKTIGSNAPTGPGLLRGVELAN
TFSFLRPNDLVWNYVVENYLKGKTPAPFDLLYWNGDSTNLPGPWYCWYLRHTYLQNDLKTPGKLKVNGTPVDLGKIEAPV
YIYGSREDHIVPWKSAYGSVPLLKGKRRFVLGASGHIAGVINPPAANKRSHWINAKLPESADAWFEGAKEHPGSWWPDWS
TWLASHAGAQKAAPKGYGNADYPAIEPAPGRYVKQKA

Sequences:

>Translated_597_residues
MASRQSTSSKASSAHTQAPWPGLSDPTQWAEQFKQWQAFAGAFAQPGAAAPGLGQFNGAAMGEGAAPFALIPHERLAEIQ
QKYLEEWLQIWRHMSTGESAEAVAPSDRRFSNDAWRKSPLYGYAAAFYVLNARTLMEMADAVQADVKTRERVRFAVSQWT
AAMSPSNFLATNPEAQKQLIESRGESLRTGILNMLQDMERGKISQTDETAFEIGRNVANSEGAVVFENDYFQLIQYKPLT
AKVHARPLLLVPPCINKYYILDLQPANSLVRYAVEQGNTVFLVSWRNPDASMASRTWDDYIEGGAIEAIRVAREISAQDQ
INVLGFCVGGTILSTALAVLAERGEHPAASLTLLTTLLDFTDTGILDVFVDQAQVEMREKTIGSNAPTGPGLLRGVELAN
TFSFLRPNDLVWNYVVENYLKGKTPAPFDLLYWNGDSTNLPGPWYCWYLRHTYLQNDLKTPGKLKVNGTPVDLGKIEAPV
YIYGSREDHIVPWKSAYGSVPLLKGKRRFVLGASGHIAGVINPPAANKRSHWINAKLPESADAWFEGAKEHPGSWWPDWS
TWLASHAGAQKAAPKGYGNADYPAIEPAPGRYVKQKA
>Mature_596_residues
ASRQSTSSKASSAHTQAPWPGLSDPTQWAEQFKQWQAFAGAFAQPGAAAPGLGQFNGAAMGEGAAPFALIPHERLAEIQQ
KYLEEWLQIWRHMSTGESAEAVAPSDRRFSNDAWRKSPLYGYAAAFYVLNARTLMEMADAVQADVKTRERVRFAVSQWTA
AMSPSNFLATNPEAQKQLIESRGESLRTGILNMLQDMERGKISQTDETAFEIGRNVANSEGAVVFENDYFQLIQYKPLTA
KVHARPLLLVPPCINKYYILDLQPANSLVRYAVEQGNTVFLVSWRNPDASMASRTWDDYIEGGAIEAIRVAREISAQDQI
NVLGFCVGGTILSTALAVLAERGEHPAASLTLLTTLLDFTDTGILDVFVDQAQVEMREKTIGSNAPTGPGLLRGVELANT
FSFLRPNDLVWNYVVENYLKGKTPAPFDLLYWNGDSTNLPGPWYCWYLRHTYLQNDLKTPGKLKVNGTPVDLGKIEAPVY
IYGSREDHIVPWKSAYGSVPLLKGKRRFVLGASGHIAGVINPPAANKRSHWINAKLPESADAWFEGAKEHPGSWWPDWST
WLASHAGAQKAAPKGYGNADYPAIEPAPGRYVKQKA

Specific function: Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation [H]

COG id: COG3243

COG function: function code I; Poly(3-hydroxyalkanoate) synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHA/PHB synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010963
- InterPro:   IPR010941 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF07167 PhaC_N [H]

EC number: NA

Molecular weight: Translated: 65862; Mature: 65731

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASRQSTSSKASSAHTQAPWPGLSDPTQWAEQFKQWQAFAGAFAQPGAAAPGLGQFNGAA
CCCCCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
MGEGAAPFALIPHERLAEIQQKYLEEWLQIWRHMSTGESAEAVAPSDRRFSNDAWRKSPL
CCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCC
YGYAAAFYVLNARTLMEMADAVQADVKTRERVRFAVSQWTAAMSPSNFLATNPEAQKQLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
ESRGESLRTGILNMLQDMERGKISQTDETAFEIGRNVANSEGAVVFENDYFQLIQYKPLT
HHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCEEEEEECCCE
AKVHARPLLLVPPCINKYYILDLQPANSLVRYAVEQGNTVFLVSWRNPDASMASRTWDDY
EEECCCEEEEECCCCCCEEEEEECCHHHHHHHHHHCCCEEEEEEECCCCHHHHHCCHHHH
IEGGAIEAIRVAREISAQDQINVLGFCVGGTILSTALAVLAERGEHPAASLTLLTTLLDF
HCCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
TDTGILDVFVDQAQVEMREKTIGSNAPTGPGLLRGVELANTFSFLRPNDLVWNYVVENYL
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KGKTPAPFDLLYWNGDSTNLPGPWYCWYLRHTYLQNDLKTPGKLKVNGTPVDLGKIEAPV
CCCCCCCEEEEEECCCCCCCCCCEEEHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCE
YIYGSREDHIVPWKSAYGSVPLLKGKRRFVLGASGHIAGVINPPAANKRSHWINAKLPES
EEECCCCCCCCCHHHHCCCCCEECCCCEEEEECCCCEEEEECCCCCCCCCCEECCCCCCC
ADAWFEGAKEHPGSWWPDWSTWLASHAGAQKAAPKGYGNADYPAIEPAPGRYVKQKA
HHHHHCCHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ASRQSTSSKASSAHTQAPWPGLSDPTQWAEQFKQWQAFAGAFAQPGAAAPGLGQFNGAA
CCCCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
MGEGAAPFALIPHERLAEIQQKYLEEWLQIWRHMSTGESAEAVAPSDRRFSNDAWRKSPL
CCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCC
YGYAAAFYVLNARTLMEMADAVQADVKTRERVRFAVSQWTAAMSPSNFLATNPEAQKQLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
ESRGESLRTGILNMLQDMERGKISQTDETAFEIGRNVANSEGAVVFENDYFQLIQYKPLT
HHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCEEEEEECCCE
AKVHARPLLLVPPCINKYYILDLQPANSLVRYAVEQGNTVFLVSWRNPDASMASRTWDDY
EEECCCEEEEECCCCCCEEEEEECCHHHHHHHHHHCCCEEEEEEECCCCHHHHHCCHHHH
IEGGAIEAIRVAREISAQDQINVLGFCVGGTILSTALAVLAERGEHPAASLTLLTTLLDF
HCCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
TDTGILDVFVDQAQVEMREKTIGSNAPTGPGLLRGVELANTFSFLRPNDLVWNYVVENYL
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KGKTPAPFDLLYWNGDSTNLPGPWYCWYLRHTYLQNDLKTPGKLKVNGTPVDLGKIEAPV
CCCCCCCEEEEEECCCCCCCCCCEEEHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCE
YIYGSREDHIVPWKSAYGSVPLLKGKRRFVLGASGHIAGVINPPAANKRSHWINAKLPES
EEECCCCCCCCCHHHHCCCCCEECCCCEEEEECCCCEEEEECCCCCCCCCCEECCCCCCC
ADAWFEGAKEHPGSWWPDWSTWLASHAGAQKAAPKGYGNADYPAIEPAPGRYVKQKA
HHHHHCCHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2670936; 1987116 [H]