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The map label for this gene is namA [H]

Identifier: 187927748

GI number: 187927748

Start: 690618

End: 691730

Strand: Direct

Name: namA [H]

Synonym: Rpic_0652

Alternate gene names: 187927748

Gene position: 690618-691730 (Clockwise)

Preceding gene: 187927747

Following gene: 187927754

Centisome position: 17.52

GC content: 66.04

Gene sequence:

>1113_bases
ATGAGTGCTCTCTTCCAGCCTTTCTCCCTGCGCGGTCTCACGCTTGAGAACCGCATCGTCATTTCGCCGATGTGCCAGTA
CTCGGCCGACAACGGCCAAGCCACGGCGTGGCACCACACGCATCTGGGCAGCCTGTCCCTTTCGGGCGCCGGATTGCTGA
TGATCGAAGCGACCGCGGTGTCGCCAGAAGGCCGCATCACCAACGGCTGCCTGGGTTTGTGGGACGACGCGACCGAAGCC
GCGCTTGAGCGCACGCTGGCTGCCATTCGCCAGAATGCGCTGGTGCCGATCGGCATGCAGATCGCGCACGCGGGCCGCAA
GGCTTCGAGCGCTCGGCCTTGGGAAGGCGGCGCATTGCTGGCGCTCGATGCCGGCGGCTGGGAAACGATGGGTCCCTCCC
CGCTGCCACAGCGCCCTGAAGAGCGTGCCCCGCGCGAAATGACCGATGCGGACCTCGCCCGCGTGCGCGATCAATTTGTC
GATACCGCGCGTCGGGCTGTGCGCTTGGGCCTATCGGCCATCGAACTGCATGCCGCACACGGCTATCTGCTGCACGAATT
CCTGTCGCCGATCGCCAATCAGCGCACCGATGCCTACGGCGGTTCGCGTGAGAACCGCATGCGTTATCCGCTGGAGATTT
TTGATGCGGTGCGCGCCGTGGTGCCGGACAATATTCCGGTTGGCGTGCGCGTGTCGGCCACCGATTGGGTGGAGGGCGGA
TGGGCGCCGGAGGATTCGGTGGTATTTGCGCAGGCACTGCGTGCGCGCGGCTGTGATTGGATCGATGCTTCGTCGGGCGG
TGTATCGCCGCTGCAGCAGATTCCGCTGTCGACCGGCTACCAGGTGCCGTTTGCCGAGAAGATCCGAAACGAGGCGGACA
TTCCGACCATCGCCGTCGGCCTCATCAACGAGGCGCATGAGGCGGAGGCCATCGTTGCGCAAGGGCGTGCGGATTTGGTC
GCCGTGGGCCGGGCCTTCCTCTACAACCCGCACTGGGCCTGGGCGGCGGCCGCTGAGTTGGGCGCGACGGTCACGGCGCC
GCCGCAATACTGGCGCGCTTTCCCGCGCCACGCCAAGAACCTCTTCGGCGATACGCATTTCGGCGCACGCTGA

Upstream 100 bases:

>100_bases
CTTCTTCGGTGCGAGGCTTTCGCACCGTCTGCACGATCGGGCGGATTCGGACACACTGGCGGTTTCTTTAGCCAGCCGCT
GATTGCCGAATCTCCCGATC

Downstream 100 bases:

>100_bases
CTTGCGCGAGCGTGCGCGGACGTGGCTAGCCGCGCTTGCGGAAGACCACGTCCCACACGCCGTGCCCGAGGCGCAGGCCG
CGTTTCTCGAACTTGGTGAC

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSALFQPFSLRGLTLENRIVISPMCQYSADNGQATAWHHTHLGSLSLSGAGLLMIEATAVSPEGRITNGCLGLWDDATEA
ALERTLAAIRQNALVPIGMQIAHAGRKASSARPWEGGALLALDAGGWETMGPSPLPQRPEERAPREMTDADLARVRDQFV
DTARRAVRLGLSAIELHAAHGYLLHEFLSPIANQRTDAYGGSRENRMRYPLEIFDAVRAVVPDNIPVGVRVSATDWVEGG
WAPEDSVVFAQALRARGCDWIDASSGGVSPLQQIPLSTGYQVPFAEKIRNEADIPTIAVGLINEAHEAEAIVAQGRADLV
AVGRAFLYNPHWAWAAAAELGATVTAPPQYWRAFPRHAKNLFGDTHFGAR

Sequences:

>Translated_370_residues
MSALFQPFSLRGLTLENRIVISPMCQYSADNGQATAWHHTHLGSLSLSGAGLLMIEATAVSPEGRITNGCLGLWDDATEA
ALERTLAAIRQNALVPIGMQIAHAGRKASSARPWEGGALLALDAGGWETMGPSPLPQRPEERAPREMTDADLARVRDQFV
DTARRAVRLGLSAIELHAAHGYLLHEFLSPIANQRTDAYGGSRENRMRYPLEIFDAVRAVVPDNIPVGVRVSATDWVEGG
WAPEDSVVFAQALRARGCDWIDASSGGVSPLQQIPLSTGYQVPFAEKIRNEADIPTIAVGLINEAHEAEAIVAQGRADLV
AVGRAFLYNPHWAWAAAAELGATVTAPPQYWRAFPRHAKNLFGDTHFGAR
>Mature_369_residues
SALFQPFSLRGLTLENRIVISPMCQYSADNGQATAWHHTHLGSLSLSGAGLLMIEATAVSPEGRITNGCLGLWDDATEAA
LERTLAAIRQNALVPIGMQIAHAGRKASSARPWEGGALLALDAGGWETMGPSPLPQRPEERAPREMTDADLARVRDQFVD
TARRAVRLGLSAIELHAAHGYLLHEFLSPIANQRTDAYGGSRENRMRYPLEIFDAVRAVVPDNIPVGVRVSATDWVEGGW
APEDSVVFAQALRARGCDWIDASSGGVSPLQQIPLSTGYQVPFAEKIRNEADIPTIAVGLINEAHEAEAIVAQGRADLVA
VGRAFLYNPHWAWAAAAELGATVTAPPQYWRAFPRHAKNLFGDTHFGAR

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=334, Percent_Identity=28.1437125748503, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1787939, Length=355, Percent_Identity=29.0140845070423, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17564188, Length=203, Percent_Identity=33.9901477832512, Blast_Score=117, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI72001454, Length=203, Percent_Identity=33.9901477832512, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17559802, Length=267, Percent_Identity=29.9625468164794, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17559804, Length=203, Percent_Identity=31.5270935960591, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17540738, Length=310, Percent_Identity=26.7741935483871, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17565138, Length=202, Percent_Identity=32.1782178217822, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17566914, Length=296, Percent_Identity=25.3378378378378, Blast_Score=84, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6325086, Length=247, Percent_Identity=25.5060728744939, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321973, Length=273, Percent_Identity=26.3736263736264, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 39961; Mature: 39829

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALFQPFSLRGLTLENRIVISPMCQYSADNGQATAWHHTHLGSLSLSGAGLLMIEATAV
CCCCCCCCCCCCEEECCEEEECHHHHCCCCCCCEEEEEECCCCCEEECCCEEEEEEEEEE
SPEGRITNGCLGLWDDATEAALERTLAAIRQNALVPIGMQIAHAGRKASSARPWEGGALL
CCCCCCCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCEEE
ALDAGGWETMGPSPLPQRPEERAPREMTDADLARVRDQFVDTARRAVRLGLSAIELHAAH
EEECCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHEEHHHHH
GYLLHEFLSPIANQRTDAYGGSRENRMRYPLEIFDAVRAVVPDNIPVGVRVSATDWVEGG
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
WAPEDSVVFAQALRARGCDWIDASSGGVSPLQQIPLSTGYQVPFAEKIRNEADIPTIAVG
CCCCCHHHHHHHHHHCCCCEEECCCCCCCHHHHCCCCCCCCCCHHHHHCCCCCCCEEEEH
LINEAHEAEAIVAQGRADLVAVGRAFLYNPHWAWAAAAELGATVTAPPQYWRAFPRHAKN
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LFGDTHFGAR
HCCCCCCCCC
>Mature Secondary Structure 
SALFQPFSLRGLTLENRIVISPMCQYSADNGQATAWHHTHLGSLSLSGAGLLMIEATAV
CCCCCCCCCCCEEECCEEEECHHHHCCCCCCCEEEEEECCCCCEEECCCEEEEEEEEEE
SPEGRITNGCLGLWDDATEAALERTLAAIRQNALVPIGMQIAHAGRKASSARPWEGGALL
CCCCCCCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCEEE
ALDAGGWETMGPSPLPQRPEERAPREMTDADLARVRDQFVDTARRAVRLGLSAIELHAAH
EEECCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHEEHHHHH
GYLLHEFLSPIANQRTDAYGGSRENRMRYPLEIFDAVRAVVPDNIPVGVRVSATDWVEGG
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
WAPEDSVVFAQALRARGCDWIDASSGGVSPLQQIPLSTGYQVPFAEKIRNEADIPTIAVG
CCCCCHHHHHHHHHHCCCCEEECCCCCCCHHHHCCCCCCCCCCHHHHHCCCCCCCEEEEH
LINEAHEAEAIVAQGRADLVAVGRAFLYNPHWAWAAAAELGATVTAPPQYWRAFPRHAKN
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LFGDTHFGAR
HCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA