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The map label for this gene is mltC [C]

Identifier: 187927754

GI number: 187927754

Start: 699416

End: 700603

Strand: Direct

Name: mltC [C]

Synonym: Rpic_0658

Alternate gene names: 187927754

Gene position: 699416-700603 (Clockwise)

Preceding gene: 187927748

Following gene: 187927766

Centisome position: 17.74

GC content: 65.74

Gene sequence:

>1188_bases
ATGAACGGTTGGAAAACCCTTCATTCTTCCGGGATCGGATCGGCGCTGCAACGCCGGCTCGTAGCCCCGGTTGGCCGCCG
CCTCGCGCGTGCTGGTCAAGTTGCGCTGCCTCGTAAGCTGCGCATGGAGTTGAACGCAGGGGGCGCCGCCGCGTCCCGCA
ATGAGTTGCATCCTGGCGTACTGCTGGTGTTCCGCAGCGGGCATGTCGTGCTTAATAGCATCGGCTTGCTGGCGGTGGCC
GCCGCAGTTGCGCTCTCGCTCAACAGCGAGTGGCGCGCCACGGTCGCTCAACGCGTGCTGCATTTCACGCCGGGTGTCGA
CACCAGTGTCGCCTCGGCCAATCCGTCGCCCGCGATTGCGGCTGGCGTGCAGCCGGTTGCTTTCGCACCGACGGCGCCGT
CCGCCGGTACGGGTGCCGCTCAAGCTGTAGCGCCTGCTGCGGCGCAGGGTGGCACGGTCGCGGCCGCAGGTTGGGACACG
CTTTCGAAGGTGCCGTCCGTGGCCGAGTTGGCTGCGCAGATTCCGAACACGCAAGTCGTCCGTGACGCGCGTGAGTCGGC
AACCGCCGGTACCCCGCGAGAGCAGGCTGCCGTGGCCGAATACATCGCCCGCAAGTACCGCGTGGCGGCCACTGCCACTG
GCCAGTTGGTGAAGGCGGCCTATCAGACCGGCAAGGAAGTCGGCCTGGATCCGCTGCTCATCCTGGGCGTGATGGCCATC
GAGTCCAGTTTCAACCCGTTCGCCGAAAGCGGTATGGGTGCGCAGGGTCTGATGCAGGTCATGACCAAGGTCCACCAGGA
CAAGTACGAAGTGATGGGCGGCGTTGGTGCTGCGCTCAATCCGTATGCCAACATCAAGGTCGGTGCGCTGGTGCTGAAGG
ATTGCATCGCGCGTGCAGGTTCGATCGAAGGCGGCCTGAAGCTGTATGTCGGGGCGGTCACGCAAGGCGACGGCGGCTAC
GGCGGCAAGGTGCTGCAAGAGCGGTCGCGCCTGCGCATGGTGGCCACTGGGCATCGTTCGCCCATGACGGTGGCGTCTGA
GCGCGAACCGGTGAAGCCGGTCGCGACGGCAACGCCTGTGACGCAAGCCGATGCGAAGACGCAAGCCACCAAGCCGTCCG
ACAAGCAACCGGCGGCTGGTCAACAGGAAGAGGCACGTCTGGACAATAAGTCGCAGGGCCAAGCCTGA

Upstream 100 bases:

>100_bases
ACAGCGCGGCATCCTTACTAAAAACCGTTGCGATTCGAAACGCACGGCGCCAGGCAAAAGAAAGGCGTCTACCGGATCTG
CGCAGCGGACGGAGGTAAGT

Downstream 100 bases:

>100_bases
TTGGCCCGATTCGCTGCGCTATATAGGAAAGGCCGTCCTTCGGGACGGCCTTTTCTGTTTGGGCGACGCGTAGAGTGTTT
TACCGGCTGAATAGCTTGCC

Product: lytic transglycosylase catalytic subunit

Products: N-Acetylmuramic Acid Residues; N-Acetylglucosamine Residues [C]

Alternate protein names: Transglycosylase; Transglycosylase SLT Family Protein; Transglycosylase SLT Family; Lytic Transglycosylase; Transglycosylase SLT Domain-Containing Lipoprotein; Transmembrane Protein; Transglycosylase Protein; Transglycosylase SLT Domain-Containing; Transmembrane Transglycosylase SLT Family Protein; Transglycosylase Transmembrane Protein

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MNGWKTLHSSGIGSALQRRLVAPVGRRLARAGQVALPRKLRMELNAGGAAASRNELHPGVLLVFRSGHVVLNSIGLLAVA
AAVALSLNSEWRATVAQRVLHFTPGVDTSVASANPSPAIAAGVQPVAFAPTAPSAGTGAAQAVAPAAAQGGTVAAAGWDT
LSKVPSVAELAAQIPNTQVVRDARESATAGTPREQAAVAEYIARKYRVAATATGQLVKAAYQTGKEVGLDPLLILGVMAI
ESSFNPFAESGMGAQGLMQVMTKVHQDKYEVMGGVGAALNPYANIKVGALVLKDCIARAGSIEGGLKLYVGAVTQGDGGY
GGKVLQERSRLRMVATGHRSPMTVASEREPVKPVATATPVTQADAKTQATKPSDKQPAAGQQEEARLDNKSQGQA

Sequences:

>Translated_395_residues
MNGWKTLHSSGIGSALQRRLVAPVGRRLARAGQVALPRKLRMELNAGGAAASRNELHPGVLLVFRSGHVVLNSIGLLAVA
AAVALSLNSEWRATVAQRVLHFTPGVDTSVASANPSPAIAAGVQPVAFAPTAPSAGTGAAQAVAPAAAQGGTVAAAGWDT
LSKVPSVAELAAQIPNTQVVRDARESATAGTPREQAAVAEYIARKYRVAATATGQLVKAAYQTGKEVGLDPLLILGVMAI
ESSFNPFAESGMGAQGLMQVMTKVHQDKYEVMGGVGAALNPYANIKVGALVLKDCIARAGSIEGGLKLYVGAVTQGDGGY
GGKVLQERSRLRMVATGHRSPMTVASEREPVKPVATATPVTQADAKTQATKPSDKQPAAGQQEEARLDNKSQGQA
>Mature_395_residues
MNGWKTLHSSGIGSALQRRLVAPVGRRLARAGQVALPRKLRMELNAGGAAASRNELHPGVLLVFRSGHVVLNSIGLLAVA
AAVALSLNSEWRATVAQRVLHFTPGVDTSVASANPSPAIAAGVQPVAFAPTAPSAGTGAAQAVAPAAAQGGTVAAAGWDT
LSKVPSVAELAAQIPNTQVVRDARESATAGTPREQAAVAEYIARKYRVAATATGQLVKAAYQTGKEVGLDPLLILGVMAI
ESSFNPFAESGMGAQGLMQVMTKVHQDKYEVMGGVGAALNPYANIKVGALVLKDCIARAGSIEGGLKLYVGAVTQGDGGY
GGKVLQERSRLRMVATGHRSPMTVASEREPVKPVATATPVTQADAKTQATKPSDKQPAAGQQEEARLDNKSQGQA

Specific function: Murein-Degrading Enzyme. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division (By Similarity). [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 40537; Mature: 40537

Theoretical pI: Translated: 10.51; Mature: 10.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGWKTLHSSGIGSALQRRLVAPVGRRLARAGQVALPRKLRMELNAGGAAASRNELHPGV
CCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEECCCCCCCCCCCCCCCE
LLVFRSGHVVLNSIGLLAVAAAVALSLNSEWRATVAQRVLHFTPGVDTSVASANPSPAIA
EEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
AGVQPVAFAPTAPSAGTGAAQAVAPAAAQGGTVAAAGWDTLSKVPSVAELAAQIPNTQVV
HCCCCEEECCCCCCCCCCCHHHHCCHHCCCCEEEECCCHHHHHCCHHHHHHHHCCCHHHH
RDARESATAGTPREQAAVAEYIARKYRVAATATGQLVKAAYQTGKEVGLDPLLILGVMAI
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHH
ESSFNPFAESGMGAQGLMQVMTKVHQDKYEVMGGVGAALNPYANIKVGALVLKDCIARAG
HHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCC
SIEGGLKLYVGAVTQGDGGYGGKVLQERSRLRMVATGHRSPMTVASEREPVKPVATATPV
CCCCCEEEEEEEEECCCCCCCHHHHHHHHHHEEHCCCCCCCCEECCCCCCCCCCCCCCCC
TQADAKTQATKPSDKQPAAGQQEEARLDNKSQGQA
CCCCCHHCCCCCCCCCCCCCCHHHHHCCCCCCCCC
>Mature Secondary Structure
MNGWKTLHSSGIGSALQRRLVAPVGRRLARAGQVALPRKLRMELNAGGAAASRNELHPGV
CCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEECCCCCCCCCCCCCCCE
LLVFRSGHVVLNSIGLLAVAAAVALSLNSEWRATVAQRVLHFTPGVDTSVASANPSPAIA
EEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
AGVQPVAFAPTAPSAGTGAAQAVAPAAAQGGTVAAAGWDTLSKVPSVAELAAQIPNTQVV
HCCCCEEECCCCCCCCCCCHHHHCCHHCCCCEEEECCCHHHHHCCHHHHHHHHCCCHHHH
RDARESATAGTPREQAAVAEYIARKYRVAATATGQLVKAAYQTGKEVGLDPLLILGVMAI
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHH
ESSFNPFAESGMGAQGLMQVMTKVHQDKYEVMGGVGAALNPYANIKVGALVLKDCIARAG
HHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCC
SIEGGLKLYVGAVTQGDGGYGGKVLQERSRLRMVATGHRSPMTVASEREPVKPVATATPV
CCCCCEEEEEEEEECCCCCCCHHHHHHHHHHEEHCCCCCCCCEECCCCCCCCCCCCCCCC
TQADAKTQATKPSDKQPAAGQQEEARLDNKSQGQA
CCCCCHHCCCCCCCCCCCCCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA