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The map label for this gene is uppP

Identifier: 187927747

GI number: 187927747

Start: 689617

End: 690498

Strand: Direct

Name: uppP

Synonym: Rpic_0651

Alternate gene names: 187927747

Gene position: 689617-690498 (Clockwise)

Preceding gene: 187927746

Following gene: 187927748

Centisome position: 17.49

GC content: 59.86

Gene sequence:

>882_bases
ATGGATATCGCACTCGCCATCAAAGCGCTGATTCTCGGCATCGTCGAAGGCCTGACCGAGTTCCTCCCCATTTCCAGCAC
CGGCCATCTGATCCTCGCTGGCCAGCTGCTCGACTTCAATGACGAGAAGGGCAAGATCTTCGAGATCGTGATCCAGTTCG
GCGCCATCCTGGCGGTGTGCTGGGAGTTCCGCCACAAAATCATCGACGTGATCAAGGGCTTGCCGAATGACCCGCGTCAG
CAGCGTTTTGCGATCAACGTGATCGTGGCGACGATTCCTGCGATCACGCTAGCGCTGATCTTTGGCAAGGCGATCAAGGC
GCATCTGTTCAATCCGATCGTGGTGGCGTCGGCGTTCATCCTCGGCGGCTTCGTGATCCTGTGGGCCGAATGGCGCGAAC
GCCATCGCGGCGAGACACATGACCCGCGCGCCAACGCACTGCTCGAAGCCGCCAAGGCTGGCGCGCCACGCATTGAAACG
CTGGACGACCTGCGCATCTCCGATGCTATCAAGGTGGGCTTCGCGCAGTGCTTCGCGCTGATTCCGGGTACGTCGCGCTC
GGGCTCGACCATCATCGGCGGCCTGCTGTTCGGCCTGTCGCGCAAGGTGGCGACGGAGTTCTCGTTTTTCCTGGCGATTC
CCGTGATTTTCGGCGCGACGGTGTACGAGTTATACAAGTCACGCGCGTTGCTGTCGGCCGATGATCTGTCGATCTTCGCA
GTGGGTTTTGTGGCCGCATTCATCTCGGCGTTCTTCTGCGTGCGCTGGCTGCTGAAGTTCATTGCCACGCACGATTTCCG
AGGATTTGCGTGGTACCGGATCATCTTCGGCATCATTGTTCTGGCGACCGCTTATACGCACCTCATCGCCTGGCAGGCCT
GA

Upstream 100 bases:

>100_bases
ATCACGGTTTTGCCCGAAGGCGTGCACGTCCAGGCCAAGCGGCCCTGAGTTCTGCTGCACGTCCAGCGCTTCGTTTTCCT
CTTCCTTCTTTGCTTACTGC

Downstream 100 bases:

>100_bases
GCCACAGGCAAGCATTTCCCTTCTTCGGTGCGAGGCTTTCGCACCGTCTGCACGATCGGGCGGATTCGGACACACTGGCG
GTTTCTTTAGCCAGCCGCTG

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MDIALAIKALILGIVEGLTEFLPISSTGHLILAGQLLDFNDEKGKIFEIVIQFGAILAVCWEFRHKIIDVIKGLPNDPRQ
QRFAINVIVATIPAITLALIFGKAIKAHLFNPIVVASAFILGGFVILWAEWRERHRGETHDPRANALLEAAKAGAPRIET
LDDLRISDAIKVGFAQCFALIPGTSRSGSTIIGGLLFGLSRKVATEFSFFLAIPVIFGATVYELYKSRALLSADDLSIFA
VGFVAAFISAFFCVRWLLKFIATHDFRGFAWYRIIFGIIVLATAYTHLIAWQA

Sequences:

>Translated_293_residues
MDIALAIKALILGIVEGLTEFLPISSTGHLILAGQLLDFNDEKGKIFEIVIQFGAILAVCWEFRHKIIDVIKGLPNDPRQ
QRFAINVIVATIPAITLALIFGKAIKAHLFNPIVVASAFILGGFVILWAEWRERHRGETHDPRANALLEAAKAGAPRIET
LDDLRISDAIKVGFAQCFALIPGTSRSGSTIIGGLLFGLSRKVATEFSFFLAIPVIFGATVYELYKSRALLSADDLSIFA
VGFVAAFISAFFCVRWLLKFIATHDFRGFAWYRIIFGIIVLATAYTHLIAWQA
>Mature_293_residues
MDIALAIKALILGIVEGLTEFLPISSTGHLILAGQLLDFNDEKGKIFEIVIQFGAILAVCWEFRHKIIDVIKGLPNDPRQ
QRFAINVIVATIPAITLALIFGKAIKAHLFNPIVVASAFILGGFVILWAEWRERHRGETHDPRANALLEAAKAGAPRIET
LDDLRISDAIKVGFAQCFALIPGTSRSGSTIIGGLLFGLSRKVATEFSFFLAIPVIFGATVYELYKSRALLSADDLSIFA
VGFVAAFISAFFCVRWLLKFIATHDFRGFAWYRIIFGIIVLATAYTHLIAWQA

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=281, Percent_Identity=41.9928825622776, Blast_Score=201, Evalue=6e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_RALPJ (B2U7E0)

Other databases:

- EMBL:   CP001068
- RefSeq:   YP_001898234.1
- GeneID:   6288764
- GenomeReviews:   CP001068_GR
- KEGG:   rpi:Rpic_0651
- HOGENOM:   HBG391969
- OMA:   FIVIENR
- ProtClustDB:   PRK00281
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 32233; Mature: 32233

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x112fecac)-; HASH(0x1428f378)-; HASH(0x13072178)-; HASH(0x145f45dc)-; HASH(0x140630b0)-; HASH(0x142882d8)-; HASH(0x1350a344)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIALAIKALILGIVEGLTEFLPISSTGHLILAGQLLDFNDEKGKIFEIVIQFGAILAVC
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
WEFRHKIIDVIKGLPNDPRQQRFAINVIVATIPAITLALIFGKAIKAHLFNPIVVASAFI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LGGFVILWAEWRERHRGETHDPRANALLEAAKAGAPRIETLDDLRISDAIKVGFAQCFAL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IPGTSRSGSTIIGGLLFGLSRKVATEFSFFLAIPVIFGATVYELYKSRALLSADDLSIFA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
VGFVAAFISAFFCVRWLLKFIATHDFRGFAWYRIIFGIIVLATAYTHLIAWQA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MDIALAIKALILGIVEGLTEFLPISSTGHLILAGQLLDFNDEKGKIFEIVIQFGAILAVC
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
WEFRHKIIDVIKGLPNDPRQQRFAINVIVATIPAITLALIFGKAIKAHLFNPIVVASAFI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LGGFVILWAEWRERHRGETHDPRANALLEAAKAGAPRIETLDDLRISDAIKVGFAQCFAL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IPGTSRSGSTIIGGLLFGLSRKVATEFSFFLAIPVIFGATVYELYKSRALLSADDLSIFA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
VGFVAAFISAFFCVRWLLKFIATHDFRGFAWYRIIFGIIVLATAYTHLIAWQA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA