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The map label for this gene is mreB [H]

Identifier: 187735047

GI number: 187735047

Start: 637337

End: 638368

Strand: Direct

Name: mreB [H]

Synonym: Amuc_0540

Alternate gene names: 187735047

Gene position: 637337-638368 (Clockwise)

Preceding gene: 187735044

Following gene: 187735048

Centisome position: 23.92

GC content: 59.3

Gene sequence:

>1032_bases
ATGTCATCTTTCTTTCAGAAAATTGTCAAACTTTTCTCCTATGACATTGGCATTGACCTGGGCACCGCCAACACCCTGGT
CAACGTCAAGGACCAGGGCATCGTTCTGCGCGAGCCTTCGGTTGTCGCCGTCAAGGGGGACAAGGTTCTGGCCGTGGGAG
ACGAAGCCAAGCGCATGCTGGGCCGCACCCCCGGCTCCGTCACGGCCATCCGGCCGTTGAAGGACGGCGTCATCGCCGAT
TTCTACATCACGGAGGAAATGCTCCGCTACTTCATCAAAAAAGCCACGGCCAGGTACTACCTGATTAAGCCGCGCGTGCT
CATCGCCATCCCCTCCGGCATTACGGAAGTGGAACGCAGGGCCGTCAAGGAATCCGCGGAAGCGGCCGGAGCCCGCCGCG
TGCATCTGATTGAAGAACCCATGGCCGCCGCCATCGGTGTAGGCCTTCCGGTTCAGGAAGCTGCGGGCAACATGATTGTG
GACATCGGCGGCGGCACGACGGAAGTGGCGCTTATTTCCCTTTCCGGCATCGTTTACAGCCGTTCCGTCCGCTGCGCCGG
GGATGAACTGGACGACGCCATCATCTCCTACATGAGGAGAACCTACAATCTCATGGTCGGGGAACGTACTGCCGAAGACA
TCAAAATCCGTATCGGCTCCGCCTATCCCCTGCCTCAGGAACTCTCTATCGAGGTCAAGGGCCGCGACCTGGTCGCGGGC
CTGCCCAAGACAGTGACGATTCGATCGGAAGAAGTGCGTGAAGCGCTCACGGAACAGCTCAACACGATTGTTGACGCCGT
GCGGACGACTTTGGAACGCTGCCCCCCTGAACTGGCCGCCGACCTTGTGGACCGGGGGATTGTTCTGGCTGGAGGAGGCG
CTCTGCTGCGCGGTCTGGATCAGCTCCTGCATGAACAGACGGGACTGCCCATCCACATTGCGGAAGACCCTCTGAGCGCT
GTTGCGGAAGGTACCGGGAAAGCCCTCCAGGAACTGGACTTCTTCACTAATGTTACTGATGCGGAAGACTAA

Upstream 100 bases:

>100_bases
CCCCGGTCCGAGTGCCAGGTTTTCAGTCCCGTGAAAAGGAAAAAGCGAGGCGTTCCTCCACCGGCTGTCTCAGGGCTATG
CCTTTATCCACTAGTTTTTT

Downstream 100 bases:

>100_bases
AAACGGAATCTCCGGAGCAAGCGCTCCGGCCTTGCGTCTGCCGTACTGCCGCATCACATCAACGCAACTGCCTGCATGAT
TCCTTTCCGGCCATCCCTAC

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MSSFFQKIVKLFSYDIGIDLGTANTLVNVKDQGIVLREPSVVAVKGDKVLAVGDEAKRMLGRTPGSVTAIRPLKDGVIAD
FYITEEMLRYFIKKATARYYLIKPRVLIAIPSGITEVERRAVKESAEAAGARRVHLIEEPMAAAIGVGLPVQEAAGNMIV
DIGGGTTEVALISLSGIVYSRSVRCAGDELDDAIISYMRRTYNLMVGERTAEDIKIRIGSAYPLPQELSIEVKGRDLVAG
LPKTVTIRSEEVREALTEQLNTIVDAVRTTLERCPPELAADLVDRGIVLAGGGALLRGLDQLLHEQTGLPIHIAEDPLSA
VAEGTGKALQELDFFTNVTDAED

Sequences:

>Translated_343_residues
MSSFFQKIVKLFSYDIGIDLGTANTLVNVKDQGIVLREPSVVAVKGDKVLAVGDEAKRMLGRTPGSVTAIRPLKDGVIAD
FYITEEMLRYFIKKATARYYLIKPRVLIAIPSGITEVERRAVKESAEAAGARRVHLIEEPMAAAIGVGLPVQEAAGNMIV
DIGGGTTEVALISLSGIVYSRSVRCAGDELDDAIISYMRRTYNLMVGERTAEDIKIRIGSAYPLPQELSIEVKGRDLVAG
LPKTVTIRSEEVREALTEQLNTIVDAVRTTLERCPPELAADLVDRGIVLAGGGALLRGLDQLLHEQTGLPIHIAEDPLSA
VAEGTGKALQELDFFTNVTDAED
>Mature_342_residues
SSFFQKIVKLFSYDIGIDLGTANTLVNVKDQGIVLREPSVVAVKGDKVLAVGDEAKRMLGRTPGSVTAIRPLKDGVIADF
YITEEMLRYFIKKATARYYLIKPRVLIAIPSGITEVERRAVKESAEAAGARRVHLIEEPMAAAIGVGLPVQEAAGNMIVD
IGGGTTEVALISLSGIVYSRSVRCAGDELDDAIISYMRRTYNLMVGERTAEDIKIRIGSAYPLPQELSIEVKGRDLVAGL
PKTVTIRSEEVREALTEQLNTIVDAVRTTLERCPPELAADLVDRGIVLAGGGALLRGLDQLLHEQTGLPIHIAEDPLSAV
AEGTGKALQELDFFTNVTDAED

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Homo sapiens, GI16507237, Length=360, Percent_Identity=25.2777777777778, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI34419635, Length=381, Percent_Identity=25.7217847769029, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082236, Length=338, Percent_Identity=60.0591715976331, Blast_Score=406, Evalue=1e-114,
Organism=Escherichia coli, GI1786870, Length=179, Percent_Identity=30.1675977653631, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17568549, Length=357, Percent_Identity=26.890756302521, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17534771, Length=356, Percent_Identity=25.8426966292135, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322426, Length=358, Percent_Identity=25.9776536312849, Blast_Score=62, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24641406, Length=366, Percent_Identity=25.1366120218579, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641408, Length=366, Percent_Identity=25.1366120218579, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641402, Length=366, Percent_Identity=25.1366120218579, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641404, Length=366, Percent_Identity=25.1366120218579, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 37027; Mature: 36896

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSFFQKIVKLFSYDIGIDLGTANTLVNVKDQGIVLREPSVVAVKGDKVLAVGDEAKRML
CCHHHHHHHHHHHHHCCEEECCCCEEEEECCCCEEEECCCEEEEECCEEEEECHHHHHHH
GRTPGSVTAIRPLKDGVIADFYITEEMLRYFIKKATARYYLIKPRVLIAIPSGITEVERR
CCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHCCEEEEECCEEEEEECCCHHHHHHH
AVKESAEAAGARRVHLIEEPMAAAIGVGLPVQEAAGNMIVDIGGGTTEVALISLSGIVYS
HHHHHHHHCCCEEEEEHHHHHHHHHCCCCCHHHCCCCEEEEECCCCEEEEEEEEHHHHEE
RSVRCAGDELDDAIISYMRRTYNLMVGERTAEDIKIRIGSAYPLPQELSIEVKGRDLVAG
CCEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEECCCCEECC
LPKTVTIRSEEVREALTEQLNTIVDAVRTTLERCPPELAADLVDRGIVLAGGGALLRGLD
CCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEECCHHHHHHHH
QLLHEQTGLPIHIAEDPLSAVAEGTGKALQELDFFTNVTDAED
HHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SSFFQKIVKLFSYDIGIDLGTANTLVNVKDQGIVLREPSVVAVKGDKVLAVGDEAKRML
CHHHHHHHHHHHHHCCEEECCCCEEEEECCCCEEEECCCEEEEECCEEEEECHHHHHHH
GRTPGSVTAIRPLKDGVIADFYITEEMLRYFIKKATARYYLIKPRVLIAIPSGITEVERR
CCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHCCEEEEECCEEEEEECCCHHHHHHH
AVKESAEAAGARRVHLIEEPMAAAIGVGLPVQEAAGNMIVDIGGGTTEVALISLSGIVYS
HHHHHHHHCCCEEEEEHHHHHHHHHCCCCCHHHCCCCEEEEECCCCEEEEEEEEHHHHEE
RSVRCAGDELDDAIISYMRRTYNLMVGERTAEDIKIRIGSAYPLPQELSIEVKGRDLVAG
CCEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEECCCCEECC
LPKTVTIRSEEVREALTEQLNTIVDAVRTTLERCPPELAADLVDRGIVLAGGGALLRGLD
CCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEECCHHHHHHHH
QLLHEQTGLPIHIAEDPLSAVAEGTGKALQELDFFTNVTDAED
HHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]