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The map label for this gene is purQ [H]

Identifier: 187735042

GI number: 187735042

Start: 630811

End: 631518

Strand: Direct

Name: purQ [H]

Synonym: Amuc_0535

Alternate gene names: 187735042

Gene position: 630811-631518 (Clockwise)

Preceding gene: 187735041

Following gene: 187735043

Centisome position: 23.68

GC content: 60.59

Gene sequence:

>708_bases
ATGCCTCACGCACTTTTACTGAAATACCCCGGCACCAACTGCGATGTGGAAACGGAACGCGCCCTGCGCGCGGCAGGGTT
CTCCACCCAGATCCAGCCCATCGCCACGGCTACGCCGGAACACGTCGCAAAATCCCAGCTTGTCGTCCTGGGCGGCGGCT
TCAGCTACGGAGACTACGTCACCAGCGGCCGCCTGGCCCAGTTGGAAACGGAACGCTTCCTGGGAGATGCCCTGCAGCGG
CACCATGCCGGAGGAGGCATGCTCCTGGGCATCTGCAACGGGTTCCAGATTCTCACCAAGCTGGGCATTCTTCCCGACTC
CAGCCTGATTGACAACAAAAAGGAACGCTTTGAATGCGTCTGGGCTAAACTGGTGAAAGTAGCCAGGAACTCTCCCTTCC
TTCAAGGCCTGCCGGATGAATTCGAACTGCCCTCCGCCCATGCGGAAGGGCGCCTGGTCACCCGTCCCGGAGATGCGGAA
AAATACCTGGCTTCCGGGAATGTGGCTCTCCAGTACGTAGACAACCGCGACGGCTGCGAATGCAGTATCGCCGGCCTCCA
GGATTCCACCGGGCGCGCCATGGGTCTGATGCCCCATCCGGAACGCTTTCTGCTGCCCCGCCACCACTATGACAAGGACT
GGGCCGGCAACGAAGACTGGGGCTGGGGGTACTTCCTCTTCAAATCCGCCTTTGACGCCCTGAAATAA

Upstream 100 bases:

>100_bases
CATAGCCAACCTCAAAAAACTCTGGAAGGACGGACTTACCCCCTATTATTGACCTCCTGAAACCGGCATCTTATCAAACC
ATCGATTTATTTCTACCAAT

Downstream 100 bases:

>100_bases
AGGTCCATTTCCCATTAACCGCTCCCCCCGCATTCATTCCATGACAGATACGGCCCTCATCGGTTCTTCTTGCGCCCTCG
GCGTTTTCTGGTCCTCAAAA

Product: Phosphoribosylformylglycinamidine synthase

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MPHALLLKYPGTNCDVETERALRAAGFSTQIQPIATATPEHVAKSQLVVLGGGFSYGDYVTSGRLAQLETERFLGDALQR
HHAGGGMLLGICNGFQILTKLGILPDSSLIDNKKERFECVWAKLVKVARNSPFLQGLPDEFELPSAHAEGRLVTRPGDAE
KYLASGNVALQYVDNRDGCECSIAGLQDSTGRAMGLMPHPERFLLPRHHYDKDWAGNEDWGWGYFLFKSAFDALK

Sequences:

>Translated_235_residues
MPHALLLKYPGTNCDVETERALRAAGFSTQIQPIATATPEHVAKSQLVVLGGGFSYGDYVTSGRLAQLETERFLGDALQR
HHAGGGMLLGICNGFQILTKLGILPDSSLIDNKKERFECVWAKLVKVARNSPFLQGLPDEFELPSAHAEGRLVTRPGDAE
KYLASGNVALQYVDNRDGCECSIAGLQDSTGRAMGLMPHPERFLLPRHHYDKDWAGNEDWGWGYFLFKSAFDALK
>Mature_234_residues
PHALLLKYPGTNCDVETERALRAAGFSTQIQPIATATPEHVAKSQLVVLGGGFSYGDYVTSGRLAQLETERFLGDALQRH
HAGGGMLLGICNGFQILTKLGILPDSSLIDNKKERFECVWAKLVKVARNSPFLQGLPDEFELPSAHAEGRLVTRPGDAEK
YLASGNVALQYVDNRDGCECSIAGLQDSTGRAMGLMPHPERFLLPRHHYDKDWAGNEDWGWGYFLFKSAFDALK

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=246, Percent_Identity=28.8617886178862, Blast_Score=75, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24582111, Length=228, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24582109, Length=228, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI17137292, Length=228, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR010075
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 25849; Mature: 25717

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHALLLKYPGTNCDVETERALRAAGFSTQIQPIATATPEHVAKSQLVVLGGGFSYGDYV
CCCEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHCCCEEEEEECCCCCCCHH
TSGRLAQLETERFLGDALQRHHAGGGMLLGICNGFQILTKLGILPDSSLIDNKKERFECV
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCCCHHHCCHHHHHHHH
WAKLVKVARNSPFLQGLPDEFELPSAHAEGRLVTRPGDAEKYLASGNVALQYVDNRDGCE
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHEECCCEEEEEECCCCCCE
CSIAGLQDSTGRAMGLMPHPERFLLPRHHYDKDWAGNEDWGWGYFLFKSAFDALK
EEEECCCCCCCCEECCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
PHALLLKYPGTNCDVETERALRAAGFSTQIQPIATATPEHVAKSQLVVLGGGFSYGDYV
CCEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHCCCEEEEEECCCCCCCHH
TSGRLAQLETERFLGDALQRHHAGGGMLLGICNGFQILTKLGILPDSSLIDNKKERFECV
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCCCHHHCCHHHHHHHH
WAKLVKVARNSPFLQGLPDEFELPSAHAEGRLVTRPGDAEKYLASGNVALQYVDNRDGCE
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHEECCCEEEEEECCCCCCE
CSIAGLQDSTGRAMGLMPHPERFLLPRHHYDKDWAGNEDWGWGYFLFKSAFDALK
EEEECCCCCCCCEECCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA