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The map label for this gene is nahA [H]

Identifier: 187734877

GI number: 187734877

Start: 436606

End: 438603

Strand: Direct

Name: nahA [H]

Synonym: Amuc_0369

Alternate gene names: 187734877

Gene position: 436606-438603 (Clockwise)

Preceding gene: 187734872

Following gene: 187734884

Centisome position: 16.39

GC content: 54.25

Gene sequence:

>1998_bases
ATGAAATTCATTATCCCCGCACTCGCCCTGTCCGCCTGCCTTCCCGCAGCCTTCTCACAAGAACAAATCATCCCGAAACC
GGCGGAAATCACATTGTTCACAGGAAGTCCGGCCCGTCTCACACCGGATTCCCTCATCATCACGGAAACACAGGACAAAG
CTTTCCTGGATCAGGCAGGGCAATTGCAGCAGATGCTCAGCGCAGGGACGGGACTCCCCCTTCCCCTTAAACCGGCCGGG
CAAGCGTCGAAAAAAGCCGCCTGCATTGTCATCAAAAAAGACCCAGCCCTGGCCGCCAGGGGAGAAGAAGCCTACTCCAT
CCAATCATCCCCAAGTGGAATCATCCTTTCCGCAGCCGATGCCAGGGGCATCTTTTACGCGGGGCAAAGCCTGGTCCAGA
TGATGCCCTCCGTCTTCCACGACCGGACGGGGGATAAATCCGCCGTCCGGTGGAATATTTCTGAAACTCCGTTCCGCATA
ACGGACTACCCGCGATTCTCCTGGCGGGCGCTGATGATTGATGAAGCACGCCACTTCTTTGGCGAGAAAACCATTAAACA
GATCATCGACCAAATGGCTCTGCTGAAAATGAACATCCTGCACTGGCACCTGACGGACGACACAGGATGGCGCATTGAAA
TCAAGAAGTATCCGCGCCTGACCTCCATCGGCTCCAAACGCAGGGAATCAGAAATCGGCACATGGAACAGCGGCAAGTCA
GACGGAACGCCGCATGAAGGCTTTTATACCCAGGAACAGATCAGGGATATCGTACAATACGCAGCCCGCCGAAACATCAC
CATCGTTCCGGAAATTGAAATGCCGGGCCATGCCAGCGCCGCCGCCGTAGCATACCCCTTCCTGAGCCTGAAAACTCCCG
GGGAAGTGCCCACAACATTCATCGTCAATACGGCCTTCGATCCCACCTCGGAAAAAACTTATGCCTTCCTGTCCGATGTT
TTGGATGAAGTCACGGCGATCTTCCCCGGCAGAATCATCCACATTGGCGGAGATGAAGTGCGCTATGACAAGCAATGGAA
GGGGGTTCCGGAAATTGAGGAATTCATGAAAAAAAACGGCATGAAAAGTTATGCGGACGTCCAGATGCATTTCACCAACC
GCATGTCCGGCATTATTGCCCAAAAAGGGCGCCGCATGATGGGATGGAATGAAATTTACGGACATGACGTCAATGGGGAC
GGAGGAGGAAAAGCCGGCGCCAAACTGGATACAAACGCCGTCATCCAGTTCTGGAAGGGCAACACCAGCCTGGCTAAAAA
CGCCATCCGGGACGGGCATGACGTTATCAATTCCCTCCACACCTCCACCTATTTGGATTACAGCTACGGCAGCATTCCCC
TGCAAAAGGCATACGGGTTCGAACCCGTTTTCCCCGGGTTGGAGAAACAGTACCATTCCAGAGTCAAGGGACTGGGCGCC
CAAGTATGGACGGAATGGATTTCCACACCGGAACGCCTGCACTACCAGGCATTCCCCCGTGCCTGCGCCTTTGCGGAAGT
CGGCTGGACTCCCGCTGGTAAAAAGGATTTTCCGGATTTCAAAAAACGCTTGAAAGCGTATAGCGAGCGTATGGATCTGA
TGGGGATCAAGTTTGCCCGGAACGTCATCAGCCAAATAGACAAATCTGACTTTTTCAATACGCCCAGGATCGGCACATGG
ACGCCTGCCACCCTGACCCGGGAGGAACATTCGTTTGACGTTACCAAACTGGTCAAAGCGTCCGGCAAACACACCGTCAC
CCTGCTGTACGACAAAGGCGCCCACGCCATCGAAATCGAATCCGTAGCCCTGTATGAAAATTCCCGGGAAGTCTCCCGGG
ACGCCCATGCAGGCAGAAGCGGCGCCCATAAGGAAAATATCCAGTACATTCTGAATGCCCCGGCCCCTAGGCAAGGAGCA
ACCTATACGGTCAAAGCAAACTTCAAAGGGGCCGGAGGCCGGGATTCCCACGGGACAGTGTATTTTGAAACGCCATAA

Upstream 100 bases:

>100_bases
TGAGACCAGCATGAAAAAACAATATTCAGTTCCAAGAGCCAAAAAAACGAATTCCCCATGAAAGATTGTGTCAGCAGTCT
TTGTACTTATAACCGTGTCC

Downstream 100 bases:

>100_bases
AAACACCGCCCCCGCCCCATACCAGAAACAGCAGGGGGGGCTTCACACAGAGCCCCCTTTACTCCAACAAACGGAGCACA
GCATCCGCAGACTCATGGTT

Product: Beta-N-acetylhexosaminidase

Products: NA

Alternate protein names: Beta-GlcNAcase; Beta-N-acetylhexosaminidase; Beta-NAHase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 665; Mature: 665

Protein sequence:

>665_residues
MKFIIPALALSACLPAAFSQEQIIPKPAEITLFTGSPARLTPDSLIITETQDKAFLDQAGQLQQMLSAGTGLPLPLKPAG
QASKKAACIVIKKDPALAARGEEAYSIQSSPSGIILSAADARGIFYAGQSLVQMMPSVFHDRTGDKSAVRWNISETPFRI
TDYPRFSWRALMIDEARHFFGEKTIKQIIDQMALLKMNILHWHLTDDTGWRIEIKKYPRLTSIGSKRRESEIGTWNSGKS
DGTPHEGFYTQEQIRDIVQYAARRNITIVPEIEMPGHASAAAVAYPFLSLKTPGEVPTTFIVNTAFDPTSEKTYAFLSDV
LDEVTAIFPGRIIHIGGDEVRYDKQWKGVPEIEEFMKKNGMKSYADVQMHFTNRMSGIIAQKGRRMMGWNEIYGHDVNGD
GGGKAGAKLDTNAVIQFWKGNTSLAKNAIRDGHDVINSLHTSTYLDYSYGSIPLQKAYGFEPVFPGLEKQYHSRVKGLGA
QVWTEWISTPERLHYQAFPRACAFAEVGWTPAGKKDFPDFKKRLKAYSERMDLMGIKFARNVISQIDKSDFFNTPRIGTW
TPATLTREEHSFDVTKLVKASGKHTVTLLYDKGAHAIEIESVALYENSREVSRDAHAGRSGAHKENIQYILNAPAPRQGA
TYTVKANFKGAGGRDSHGTVYFETP

Sequences:

>Translated_665_residues
MKFIIPALALSACLPAAFSQEQIIPKPAEITLFTGSPARLTPDSLIITETQDKAFLDQAGQLQQMLSAGTGLPLPLKPAG
QASKKAACIVIKKDPALAARGEEAYSIQSSPSGIILSAADARGIFYAGQSLVQMMPSVFHDRTGDKSAVRWNISETPFRI
TDYPRFSWRALMIDEARHFFGEKTIKQIIDQMALLKMNILHWHLTDDTGWRIEIKKYPRLTSIGSKRRESEIGTWNSGKS
DGTPHEGFYTQEQIRDIVQYAARRNITIVPEIEMPGHASAAAVAYPFLSLKTPGEVPTTFIVNTAFDPTSEKTYAFLSDV
LDEVTAIFPGRIIHIGGDEVRYDKQWKGVPEIEEFMKKNGMKSYADVQMHFTNRMSGIIAQKGRRMMGWNEIYGHDVNGD
GGGKAGAKLDTNAVIQFWKGNTSLAKNAIRDGHDVINSLHTSTYLDYSYGSIPLQKAYGFEPVFPGLEKQYHSRVKGLGA
QVWTEWISTPERLHYQAFPRACAFAEVGWTPAGKKDFPDFKKRLKAYSERMDLMGIKFARNVISQIDKSDFFNTPRIGTW
TPATLTREEHSFDVTKLVKASGKHTVTLLYDKGAHAIEIESVALYENSREVSRDAHAGRSGAHKENIQYILNAPAPRQGA
TYTVKANFKGAGGRDSHGTVYFETP
>Mature_665_residues
MKFIIPALALSACLPAAFSQEQIIPKPAEITLFTGSPARLTPDSLIITETQDKAFLDQAGQLQQMLSAGTGLPLPLKPAG
QASKKAACIVIKKDPALAARGEEAYSIQSSPSGIILSAADARGIFYAGQSLVQMMPSVFHDRTGDKSAVRWNISETPFRI
TDYPRFSWRALMIDEARHFFGEKTIKQIIDQMALLKMNILHWHLTDDTGWRIEIKKYPRLTSIGSKRRESEIGTWNSGKS
DGTPHEGFYTQEQIRDIVQYAARRNITIVPEIEMPGHASAAAVAYPFLSLKTPGEVPTTFIVNTAFDPTSEKTYAFLSDV
LDEVTAIFPGRIIHIGGDEVRYDKQWKGVPEIEEFMKKNGMKSYADVQMHFTNRMSGIIAQKGRRMMGWNEIYGHDVNGD
GGGKAGAKLDTNAVIQFWKGNTSLAKNAIRDGHDVINSLHTSTYLDYSYGSIPLQKAYGFEPVFPGLEKQYHSRVKGLGA
QVWTEWISTPERLHYQAFPRACAFAEVGWTPAGKKDFPDFKKRLKAYSERMDLMGIKFARNVISQIDKSDFFNTPRIGTW
TPATLTREEHSFDVTKLVKASGKHTVTLLYDKGAHAIEIESVALYENSREVSRDAHAGRSGAHKENIQYILNAPAPRQGA
TYTVKANFKGAGGRDSHGTVYFETP

Specific function: Unknown

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI4504373, Length=441, Percent_Identity=28.1179138321995, Blast_Score=156, Evalue=6e-38,
Organism=Homo sapiens, GI189181666, Length=408, Percent_Identity=27.9411764705882, Blast_Score=145, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17569815, Length=552, Percent_Identity=26.6304347826087, Blast_Score=158, Evalue=8e-39,
Organism=Drosophila melanogaster, GI281365639, Length=473, Percent_Identity=24.7357293868922, Blast_Score=121, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24657474, Length=473, Percent_Identity=24.7357293868922, Blast_Score=121, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24657468, Length=473, Percent_Identity=24.7357293868922, Blast_Score=121, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17647501, Length=473, Percent_Identity=24.7357293868922, Blast_Score=121, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24653074, Length=410, Percent_Identity=25.3658536585366, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI45551090, Length=410, Percent_Identity=25.3658536585366, Blast_Score=109, Evalue=6e-24,
Organism=Drosophila melanogaster, GI17933586, Length=409, Percent_Identity=25.9168704156479, Blast_Score=106, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR011658 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 73956; Mature: 73956

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIIPALALSACLPAAFSQEQIIPKPAEITLFTGSPARLTPDSLIITETQDKAFLDQAG
CCEEHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCHHHHHHHH
QLQQMLSAGTGLPLPLKPAGQASKKAACIVIKKDPALAARGEEAYSIQSSPSGIILSAAD
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEECCCCCCEEEEECC
ARGIFYAGQSLVQMMPSVFHDRTGDKSAVRWNISETPFRITDYPRFSWRALMIDEARHFF
CCEEEEHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEECCCCCCEEEEEHHHHHHHH
GEKTIKQIIDQMALLKMNILHWHLTDDTGWRIEIKKYPRLTSIGSKRRESEIGTWNSGKS
HHHHHHHHHHHHHHHHEEEEEEEEECCCCCEEEEECCCCHHHHCCHHHHCCCCCCCCCCC
DGTPHEGFYTQEQIRDIVQYAARRNITIVPEIEMPGHASAAAVAYPFLSLKTPGEVPTTF
CCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHEECCCCCCCCCEE
IVNTAFDPTSEKTYAFLSDVLDEVTAIFPGRIIHIGGDEVRYDKQWKGVPEIEEFMKKNG
EEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCCCHHHHHHHHHCC
MKSYADVQMHFTNRMSGIIAQKGRRMMGWNEIYGHDVNGDGGGKAGAKLDTNAVIQFWKG
CCCHHHEEEEHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCEECCCCEEEEECC
NTSLAKNAIRDGHDVINSLHTSTYLDYSYGSIPLQKAYGFEPVFPGLEKQYHSRVKGLGA
CHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHCHH
QVWTEWISTPERLHYQAFPRACAFAEVGWTPAGKKDFPDFKKRLKAYSERMDLMGIKFAR
HHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NVISQIDKSDFFNTPRIGTWTPATLTREEHSFDVTKLVKASGKHTVTLLYDKGAHAIEIE
HHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCHHHHHHHCCCCEEEEEEEECCCCEEEEE
SVALYENSREVSRDAHAGRSGAHKENIQYILNAPAPRQGATYTVKANFKGAGGRDSHGTV
EEEEECCCHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEE
YFETP
EEECC
>Mature Secondary Structure
MKFIIPALALSACLPAAFSQEQIIPKPAEITLFTGSPARLTPDSLIITETQDKAFLDQAG
CCEEHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCHHHHHHHH
QLQQMLSAGTGLPLPLKPAGQASKKAACIVIKKDPALAARGEEAYSIQSSPSGIILSAAD
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEECCCCCCEEEEECC
ARGIFYAGQSLVQMMPSVFHDRTGDKSAVRWNISETPFRITDYPRFSWRALMIDEARHFF
CCEEEEHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEECCCCCCEEEEEHHHHHHHH
GEKTIKQIIDQMALLKMNILHWHLTDDTGWRIEIKKYPRLTSIGSKRRESEIGTWNSGKS
HHHHHHHHHHHHHHHHEEEEEEEEECCCCCEEEEECCCCHHHHCCHHHHCCCCCCCCCCC
DGTPHEGFYTQEQIRDIVQYAARRNITIVPEIEMPGHASAAAVAYPFLSLKTPGEVPTTF
CCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHEECCCCCCCCCEE
IVNTAFDPTSEKTYAFLSDVLDEVTAIFPGRIIHIGGDEVRYDKQWKGVPEIEEFMKKNG
EEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCCCHHHHHHHHHCC
MKSYADVQMHFTNRMSGIIAQKGRRMMGWNEIYGHDVNGDGGGKAGAKLDTNAVIQFWKG
CCCHHHEEEEHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCEECCCCEEEEECC
NTSLAKNAIRDGHDVINSLHTSTYLDYSYGSIPLQKAYGFEPVFPGLEKQYHSRVKGLGA
CHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHCHH
QVWTEWISTPERLHYQAFPRACAFAEVGWTPAGKKDFPDFKKRLKAYSERMDLMGIKFAR
HHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NVISQIDKSDFFNTPRIGTWTPATLTREEHSFDVTKLVKASGKHTVTLLYDKGAHAIEIE
HHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCHHHHHHHCCCCEEEEEEEECCCCEEEEE
SVALYENSREVSRDAHAGRSGAHKENIQYILNAPAPRQGATYTVKANFKGAGGRDSHGTV
EEEEECCCHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEE
YFETP
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7881557; 12949112 [H]