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The map label for this gene is cat3 [H]

Identifier: 187734841

GI number: 187734841

Start: 390524

End: 391159

Strand: Reverse

Name: cat3 [H]

Synonym: Amuc_0333

Alternate gene names: 187734841

Gene position: 391159-390524 (Counterclockwise)

Preceding gene: 187734842

Following gene: 187734840

Centisome position: 14.68

GC content: 53.3

Gene sequence:

>636_bases
ATGAAAAAGAAAATAGAAATCTCTTCCTGGCCTCGAAAGTCTCATTATGAGTATTTCCAGACGTTTGACTGCCCCATGTT
TTCCATTACGTCCCCGGTCCGGGTGGATGCCCTGTACCGTTATGCGAAACGGGAGGGGGTTTCCTTTTTCATTTTGTGCC
TGTTTGTGCTGCTGAAGGCGTTGAACAGGGTGCCCCAGCTGCGCCAGCGGGTGGAGGAAGGGGATGTATGGGAGTATGAG
TCCGTGGATGCCCTGGTTCCAGTGCTGGCTGCGGATGGAGAATTCACTCAGATTTTAGTGGAATACCGGATGGAGTTGTC
TGATTTCCTGAAACATGCCGTTCCTCTTGTGCAGGCTGCCAAACTTGCTCCCGCCCAGGCGAATCCGTGCCATAGGGCGG
ATATCGCCGTATTCAGCTGCCTGCCGTGGATTCCATTCACACAGGTGGCCAGCGCCTACAGAGTGTTTCGGGGACAATAC
TTTCCCCTCATCCATTGGGGGAAGATGGAGGCGGATGCTTCCGGCAGGATGGTGATGCCCGTGGCCATTCAGGCAAACCA
TGTGCTGGTGGACGGGGTGCATGTGGGCCGTTTTTACGGTATTCTGGAAGAATTGTGCGGAAATCAATTCTGTTAA

Upstream 100 bases:

>100_bases
TGGGAACAGCCGGGTTGGAATTTCCGGTAGAGCCGGGGAATAATGGAAGGAAAGAAGCTGTTGTGAAACGGGGAGCCTTC
CCTGAATAGAAAATAAGTGC

Downstream 100 bases:

>100_bases
AAGGATTTTTCCGTGGCGTGGTTCCAACAGAACTTGAGTTTGTGAATTGAGGTGAATCAAGATGAATTTGAACTGGATGC
AAAATACTGAATAATAACGC

Product: chloramphenicol acetyltransferase

Products: NA

Alternate protein names: Chloramphenicol acetyltransferase III; CAT-III [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MKKKIEISSWPRKSHYEYFQTFDCPMFSITSPVRVDALYRYAKREGVSFFILCLFVLLKALNRVPQLRQRVEEGDVWEYE
SVDALVPVLAADGEFTQILVEYRMELSDFLKHAVPLVQAAKLAPAQANPCHRADIAVFSCLPWIPFTQVASAYRVFRGQY
FPLIHWGKMEADASGRMVMPVAIQANHVLVDGVHVGRFYGILEELCGNQFC

Sequences:

>Translated_211_residues
MKKKIEISSWPRKSHYEYFQTFDCPMFSITSPVRVDALYRYAKREGVSFFILCLFVLLKALNRVPQLRQRVEEGDVWEYE
SVDALVPVLAADGEFTQILVEYRMELSDFLKHAVPLVQAAKLAPAQANPCHRADIAVFSCLPWIPFTQVASAYRVFRGQY
FPLIHWGKMEADASGRMVMPVAIQANHVLVDGVHVGRFYGILEELCGNQFC
>Mature_211_residues
MKKKIEISSWPRKSHYEYFQTFDCPMFSITSPVRVDALYRYAKREGVSFFILCLFVLLKALNRVPQLRQRVEEGDVWEYE
SVDALVPVLAADGEFTQILVEYRMELSDFLKHAVPLVQAAKLAPAQANPCHRADIAVFSCLPWIPFTQVASAYRVFRGQY
FPLIHWGKMEADASGRMVMPVAIQANHVLVDGVHVGRFYGILEELCGNQFC

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG4845

COG function: function code V; Chloramphenicol O-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloramphenicol acetyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023213
- InterPro:   IPR018372
- InterPro:   IPR001707
- ProDom:   PD002660 [H]

Pfam domain/function: PF00302 CAT [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 24139; Mature: 24139

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKIEISSWPRKSHYEYFQTFDCPMFSITSPVRVDALYRYAKREGVSFFILCLFVLLKA
CCCCCCCCCCCCHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LNRVPQLRQRVEEGDVWEYESVDALVPVLAADGEFTQILVEYRMELSDFLKHAVPLVQAA
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLAPAQANPCHRADIAVFSCLPWIPFTQVASAYRVFRGQYFPLIHWGKMEADASGRMVMP
HCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCEEEE
VAIQANHVLVDGVHVGRFYGILEELCGNQFC
EEEECCEEEEECCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKKKIEISSWPRKSHYEYFQTFDCPMFSITSPVRVDALYRYAKREGVSFFILCLFVLLKA
CCCCCCCCCCCCHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LNRVPQLRQRVEEGDVWEYESVDALVPVLAADGEFTQILVEYRMELSDFLKHAVPLVQAA
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLAPAQANPCHRADIAVFSCLPWIPFTQVASAYRVFRGQYFPLIHWGKMEADASGRMVMP
HCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCEEEE
VAIQANHVLVDGVHVGRFYGILEELCGNQFC
EEEECCEEEEECCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3048245; 3288984; 2187098 [H]