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The map label for this gene is prsA [H]

Identifier: 187734680

GI number: 187734680

Start: 204502

End: 205575

Strand: Direct

Name: prsA [H]

Synonym: Amuc_0167

Alternate gene names: 187734680

Gene position: 204502-205575 (Clockwise)

Preceding gene: 187734679

Following gene: 187734681

Centisome position: 7.68

GC content: 58.57

Gene sequence:

>1074_bases
ATGTCTCCCACTGGAAAATTCACGCTCAGGCTTGTGATTTATGGAGCCTTCCTGCTCTATCTGGTGGGAGACTTGTTTGT
CTGGCACGGCTTTCTGGCCGGCAGGATGGACGCGTACCTGAAACCGTTGCCGGGGCCGCCAGGAGACAACTCCGCCCGGA
TAGCGGAAGTGTACGGGGAACCCGTCACCGCCAACCAGCTTTCCCGAAGAATGACGGAACTGAAAATGCTGCGCCAGCCT
CCCGTGCTGGATATGGAAGGCGGGATCAAACTTACTCATGAACTGGACATCCCCGGCGACCTGGCTCCGCGGGCCAGGTA
TGACCTGATCGGCTCCTCCCTTCTGCGCCTGAAAACCAGCGTCAATGACCTCCAGCTCCCCAACCGCAACGCGGAAGCGG
CACGCGCCGTGGAACAAATCCGGTCCCGTTTTGACGGAGACACGGAACAATACCTGAAAACCCTGCATGGTCAGAAATTG
ACGCAGGAACAATTTCAAAAAAAAATAGCGGCCAGGCTCAAACAGACGGAACAGCTCTACCGGGCAACCGCCCAGGCGGC
GGAAGCGTCCGACGAAGACCTGAAAACCTACTACAACCTGATCCGGGACCAGCTCACCCCTCCTGATCTGCGGAAAACCA
GGCACATCTTCCTGGCTACCCTGAACAGGGAAGAAGCCCAGGTCCGGCAAACCGCGGAAACGCTGCTGGAGCGGCTGAAG
GCAGGGGAATCCTTCTCCCGGCTCGCCAGGGAATTCAGTGAAGACGAACGTTCCGCTCCCGCAGGCGGGGAACTCGGCTG
GATAAGCCCCGCCCGCGCCAAGGAAACCCTGGGTCTGGCGTTGGCAGACGTCCCGGACAACAGGCCGGTACTTCTCAAAA
GCCGGTGGGGGTGGCACCTTGTGGAAGCATCCCCTGTCAAAAAAGGGAAAACGCCATCCTATGAAGAAGCGCTTCCGGCC
CTGAGGGATGCAGCCCGGAGCCTCAGAAAAGCTCAAGCCGTGGGATTGTACATGGACGGCCTTTTTGAAGAAGCCCATCT
CAGAAACCGCATTAAAAACAAGCAGGGCCGCTGA

Upstream 100 bases:

>100_bases
CATTGAAAAGAAGAGATTCCGCAACTTCCTTCCTCCGGAATCCGCCCGCCTGGCAGACTCCGGCGGCGGAAACTAAGCTC
TTTGCCCTCCTTCTCCTGCC

Downstream 100 bases:

>100_bases
CGCCCCAATTCCGACAAACGGGCCTTCGCAAAAATCGGAAACATCAGGCCCGCCTGCCTTTACACCTGAACATTCCCGCA
GGCCCTCCGGCTTCCAGACC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSPTGKFTLRLVIYGAFLLYLVGDLFVWHGFLAGRMDAYLKPLPGPPGDNSARIAEVYGEPVTANQLSRRMTELKMLRQP
PVLDMEGGIKLTHELDIPGDLAPRARYDLIGSSLLRLKTSVNDLQLPNRNAEAARAVEQIRSRFDGDTEQYLKTLHGQKL
TQEQFQKKIAARLKQTEQLYRATAQAAEASDEDLKTYYNLIRDQLTPPDLRKTRHIFLATLNREEAQVRQTAETLLERLK
AGESFSRLAREFSEDERSAPAGGELGWISPARAKETLGLALADVPDNRPVLLKSRWGWHLVEASPVKKGKTPSYEEALPA
LRDAARSLRKAQAVGLYMDGLFEEAHLRNRIKNKQGR

Sequences:

>Translated_357_residues
MSPTGKFTLRLVIYGAFLLYLVGDLFVWHGFLAGRMDAYLKPLPGPPGDNSARIAEVYGEPVTANQLSRRMTELKMLRQP
PVLDMEGGIKLTHELDIPGDLAPRARYDLIGSSLLRLKTSVNDLQLPNRNAEAARAVEQIRSRFDGDTEQYLKTLHGQKL
TQEQFQKKIAARLKQTEQLYRATAQAAEASDEDLKTYYNLIRDQLTPPDLRKTRHIFLATLNREEAQVRQTAETLLERLK
AGESFSRLAREFSEDERSAPAGGELGWISPARAKETLGLALADVPDNRPVLLKSRWGWHLVEASPVKKGKTPSYEEALPA
LRDAARSLRKAQAVGLYMDGLFEEAHLRNRIKNKQGR
>Mature_356_residues
SPTGKFTLRLVIYGAFLLYLVGDLFVWHGFLAGRMDAYLKPLPGPPGDNSARIAEVYGEPVTANQLSRRMTELKMLRQPP
VLDMEGGIKLTHELDIPGDLAPRARYDLIGSSLLRLKTSVNDLQLPNRNAEAARAVEQIRSRFDGDTEQYLKTLHGQKLT
QEQFQKKIAARLKQTEQLYRATAQAAEASDEDLKTYYNLIRDQLTPPDLRKTRHIFLATLNREEAQVRQTAETLLERLKA
GESFSRLAREFSEDERSAPAGGELGWISPARAKETLGLALADVPDNRPVLLKSRWGWHLVEASPVKKGKTPSYEEALPAL
RDAARSLRKAQAVGLYMDGLFEEAHLRNRIKNKQGR

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 40182; Mature: 40051

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPTGKFTLRLVIYGAFLLYLVGDLFVWHGFLAGRMDAYLKPLPGPPGDNSARIAEVYGE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCC
PVTANQLSRRMTELKMLRQPPVLDMEGGIKLTHELDIPGDLAPRARYDLIGSSLLRLKTS
CCCHHHHHHHHHHHHHHCCCCCEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
VNDLQLPNRNAEAARAVEQIRSRFDGDTEQYLKTLHGQKLTQEQFQKKIAARLKQTEQLY
HHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
RATAQAAEASDEDLKTYYNLIRDQLTPPDLRKTRHIFLATLNREEAQVRQTAETLLERLK
HHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHH
AGESFSRLAREFSEDERSAPAGGELGWISPARAKETLGLALADVPDNRPVLLKSRWGWHL
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCEECCCCCCCEEEECCCCEEE
VEASPVKKGKTPSYEEALPALRDAARSLRKAQAVGLYMDGLFEEAHLRNRIKNKQGR
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SPTGKFTLRLVIYGAFLLYLVGDLFVWHGFLAGRMDAYLKPLPGPPGDNSARIAEVYGE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCC
PVTANQLSRRMTELKMLRQPPVLDMEGGIKLTHELDIPGDLAPRARYDLIGSSLLRLKTS
CCCHHHHHHHHHHHHHHCCCCCEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
VNDLQLPNRNAEAARAVEQIRSRFDGDTEQYLKTLHGQKLTQEQFQKKIAARLKQTEQLY
HHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
RATAQAAEASDEDLKTYYNLIRDQLTPPDLRKTRHIFLATLNREEAQVRQTAETLLERLK
HHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHH
AGESFSRLAREFSEDERSAPAGGELGWISPARAKETLGLALADVPDNRPVLLKSRWGWHL
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCEECCCCCCCEEEECCCCEEE
VEASPVKKGKTPSYEEALPALRDAARSLRKAQAVGLYMDGLFEEAHLRNRIKNKQGR
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA