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The map label for this gene is tctD [H]

Identifier: 186477801

GI number: 186477801

Start: 3432892

End: 3433578

Strand: Direct

Name: tctD [H]

Synonym: Bphy_3057

Alternate gene names: 186477801

Gene position: 3432892-3433578 (Clockwise)

Preceding gene: 186477799

Following gene: 186477802

Centisome position: 98.67

GC content: 62.01

Gene sequence:

>687_bases
ATGCGACTCCTTCTGATCGAAGATGACCGCCCCATCGCACGCGGCATCCAAAGCAGTCTCGAACAAGCCGGCTTCACAGT
CGACATGGTTCACGACGGCATCTTCGCCGAACAGGCCCTCACGCAAAACCGCCACGAACTCGTGATCCTCGATCTGGGCC
TGCCCGGCATCGACGGCATGACGCTGCTCTCGCGTTTCCGCCAGAGCAATCGTCATACGCCCGTCATCGTGCTGACCGCC
CGCGACGAACTGAACGACCGCGTGCAAGGCCTCAATTCCGGTGCGGACGATTACATGCTGAAGCCGTTCGAACCCGCCGA
ACTTGAAGCGCGTATCCGCGCCGTGATGCGCCGCAGCGGCCCGCATGGCGATATGCCGCGTCCGGAAGTATCGCTGGGCG
GCGTGCGCCTGTCGGGTGTCGATCGCCGCATCTTCAACGACGACAAGCCGCTGGAATTGTCCCCGCGCGAATTCGCGGTG
CTCGAAATGTTGCTGCTGCGTCATGGCCGCGTAGTCAGCAAGGCGCAACTGCAGGATCACCTGACGCACTTCGGCGGCGA
TCTGGGCGACACCGCGATCGAAGTCTATGTGCACCGCGTGCGCAAAAAGCTTGAAAACTGCCGCGTCGAAATCGTCACGG
TGCGCGGCTTCGGCTATCTGCTCCAGGAAATCCGCCAGGCGTCATAA

Upstream 100 bases:

>100_bases
AAAGCCGCATCGAACGGCACGCCGCACGGCATTCTGTGCAGCAGGCGCACCGGCGAACCGCGTGCCTCTTGCCTAAACCC
ATTGTACTTGAGCGAAAACC

Downstream 100 bases:

>100_bases
TGGTCGTCGAGACCGTCATGGTCTGACGGCGTCCGGGTTGTCCGACGGGCGGCCGCAAGCGCATCCGCGGATGCGCGGCG
GCCGCCTGTGTCATTCAACC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MRLLLIEDDRPIARGIQSSLEQAGFTVDMVHDGIFAEQALTQNRHELVILDLGLPGIDGMTLLSRFRQSNRHTPVIVLTA
RDELNDRVQGLNSGADDYMLKPFEPAELEARIRAVMRRSGPHGDMPRPEVSLGGVRLSGVDRRIFNDDKPLELSPREFAV
LEMLLLRHGRVVSKAQLQDHLTHFGGDLGDTAIEVYVHRVRKKLENCRVEIVTVRGFGYLLQEIRQAS

Sequences:

>Translated_228_residues
MRLLLIEDDRPIARGIQSSLEQAGFTVDMVHDGIFAEQALTQNRHELVILDLGLPGIDGMTLLSRFRQSNRHTPVIVLTA
RDELNDRVQGLNSGADDYMLKPFEPAELEARIRAVMRRSGPHGDMPRPEVSLGGVRLSGVDRRIFNDDKPLELSPREFAV
LEMLLLRHGRVVSKAQLQDHLTHFGGDLGDTAIEVYVHRVRKKLENCRVEIVTVRGFGYLLQEIRQAS
>Mature_228_residues
MRLLLIEDDRPIARGIQSSLEQAGFTVDMVHDGIFAEQALTQNRHELVILDLGLPGIDGMTLLSRFRQSNRHTPVIVLTA
RDELNDRVQGLNSGADDYMLKPFEPAELEARIRAVMRRSGPHGDMPRPEVSLGGVRLSGVDRRIFNDDKPLELSPREFAV
LEMLLLRHGRVVSKAQLQDHLTHFGGDLGDTAIEVYVHRVRKKLENCRVEIVTVRGFGYLLQEIRQAS

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=38.4615384615385, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=41.7040358744395, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=34.6491228070175, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=38.5650224215247, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=32.1428571428571, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=33.9285714285714, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=35.4260089686099, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=33.920704845815, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=33.6322869955157, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=31.6964285714286, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI2367329, Length=235, Percent_Identity=36.1702127659575, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=29.646017699115, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=28.5087719298246, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=28.1385281385281, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790299, Length=102, Percent_Identity=31.3725490196078, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=30.8411214953271, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788713, Length=101, Percent_Identity=31.6831683168317, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1788191, Length=123, Percent_Identity=27.6422764227642, Blast_Score=61, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=101, Percent_Identity=34.6534653465347, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25720; Mature: 25720

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLLIEDDRPIARGIQSSLEQAGFTVDMVHDGIFAEQALTQNRHELVILDLGLPGIDGM
CEEEEEECCCHHHHHHHHHHHHHCCEEEEHHCCHHHHHHHHCCCCEEEEEECCCCCCCHH
TLLSRFRQSNRHTPVIVLTARDELNDRVQGLNSGADDYMLKPFEPAELEARIRAVMRRSG
HHHHHHHHCCCCCCEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
PHGDMPRPEVSLGGVRLSGVDRRIFNDDKPLELSPREFAVLEMLLLRHGRVVSKAQLQDH
CCCCCCCCCCEECCEEECCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
LTHFGGDLGDTAIEVYVHRVRKKLENCRVEIVTVRGFGYLLQEIRQAS
HHHHCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHCC
>Mature Secondary Structure
MRLLLIEDDRPIARGIQSSLEQAGFTVDMVHDGIFAEQALTQNRHELVILDLGLPGIDGM
CEEEEEECCCHHHHHHHHHHHHHCCEEEEHHCCHHHHHHHHCCCCEEEEEECCCCCCCHH
TLLSRFRQSNRHTPVIVLTARDELNDRVQGLNSGADDYMLKPFEPAELEARIRAVMRRSG
HHHHHHHHCCCCCCEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
PHGDMPRPEVSLGGVRLSGVDRRIFNDDKPLELSPREFAVLEMLLLRHGRVVSKAQLQDH
CCCCCCCCCCEECCEEECCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
LTHFGGDLGDTAIEVYVHRVRKKLENCRVEIVTVRGFGYLLQEIRQAS
HHHHCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]