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The map label for this gene is qseC [H]

Identifier: 186477802

GI number: 186477802

Start: 3433753

End: 3435252

Strand: Direct

Name: qseC [H]

Synonym: Bphy_3058

Alternate gene names: 186477802

Gene position: 3433753-3435252 (Clockwise)

Preceding gene: 186477801

Following gene: 186477811

Centisome position: 98.69

GC content: 65.0

Gene sequence:

>1500_bases
ATGAACTATCCCGCCGCGAATAGCCTGCGCCGCCAGCTGCTGCGCAGGCTCGCCGCTCCCCTTTCGCTGCTCGCGCTGAT
GAGCGGCCTCATAGCGTACTGGCTCGCGTGGCAATACACGCAGCATGTCGTCGATCGTTCGCTCGCCGATCTCGCGACGG
CTATCTCGAAGCAGATCCAGATCGCCGGCCCCGACGCACCGATCACCGTGCCGCCACTCGCGCAGGCGATGTTCTCCGAC
CCGGTCGAACAGCTGGTCTACCGAATCAGCAACGGCGAAACCGAAATCGCCGGCGACCCGAAGCTGCCGCTACAGGGCAC
GAACGTGCGGCGCATGCACTATGCGTATGTGTTCGAGACGCAGCACGAAGGCACGGCGGTGCGGGTTGCACAGGTACGCG
TCGATCAGCCGACGGGCAATCCCGTCGTCATCGAAGTCGGCCAGCCTGTGCACCACCGTTTTCGCATCGCCGCCGAATTT
CTCATCGCGATCATGATGCCGCTGCTGCTGTTGCTACTCGCGGGCTGGGTGATCGTGTGGCGGGTCGTCAACCAGCAATT
GAACCCGCTGACCGATCTCGCCGATTCGCTGAACCGTCAGACGCACACGTCGCTCGAACCCGTCGACGAGACCTTCGTGC
CCGTGGAGATCCGCCCGCTGACGGGTGCGCTGAATGGACTGCTCGACCGCTTGAAGTCCGCGCTCGATGCGCAGCGCAAA
TTCATCGCCGACGCTGCGCATCAACTGCGCACGCCGCTCACCGCGATCAAGCTCCACGCCGAGCAGGCGGCCATCGCCCG
CGATCCGCAGCAGACCCTTGCGGCAGTCAAGGAACTGCGTGCCGCAGCCGATCGCGCGGTGCGTCTGTCGAACCAGCTGC
TGTCTCTCGCGCGTGCCGAGCCAGGCGAACAGGCTGCGCGTTTCGTCAATCTGGACGTCGCGTCGCTCGCCTTCGACACG
GGCGCCGAATGGGTCCCGCGCGCGCTCGCCGTGCATGTCGACCTCGGTTTCCAGCGGCTCGACGATCCATCGAACGATCA
TCCGTTGATCGCACGCGGCAATCCTGTGCTGCTGCGCGAAGTGATCGCGAATTTGCTGGATAACGCGCTGAAATACGTGC
CGCCGTCGCGTATCAACGGCGCACGCATCACGATGACGGTCGCACAAGTGGTCGTGGATGGCGTCGCGATGGCGGAAGTC
GCCGTCGAGGATAACGGCCCTGGCGTACCGCTCAAGCAGCAGCCCGAGCTGTTCAAGCGCTTCTTCCGTGGCGACGGTCA
GGGGCAAAGCGACAGCAGCGTCGACGGCGGCGCGGGTCTCGGCCTTGCGATCGTGCACGACATCATGGCGCTGCATCGCG
GCAGCGTGCATTACGAAGACGCCGCCGAAGGCGGAGCGCGCTTCATCGTGCGGCTTCCCGTCGCGACGGGCGCCGTACTG
CGCGAGCCCGATCCAGCTCGAGAAACAAAAAAACCGGCGCATGCGCCGGTCGATCTCTGA

Upstream 100 bases:

>100_bases
GCGGCGGCCGCCTGTGTCATTCAACCCGGCAGCGGCGATGCATGGTCGCGCGTCCGTCGAGATCCTCCGCCGGCGTCAAT
CTTTTATCGCGGGTTCGACC

Downstream 100 bases:

>100_bases
ACTTCATCGCCAGAGCGCGCTGCCGTTGCTCTATGTCCGGCAGCGCACCTCAATCACTTCTTCTTCTTCGATTTCTTCTC
GTCTTTCTTGTCCGGCGGCG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 499

Protein sequence:

>499_residues
MNYPAANSLRRQLLRRLAAPLSLLALMSGLIAYWLAWQYTQHVVDRSLADLATAISKQIQIAGPDAPITVPPLAQAMFSD
PVEQLVYRISNGETEIAGDPKLPLQGTNVRRMHYAYVFETQHEGTAVRVAQVRVDQPTGNPVVIEVGQPVHHRFRIAAEF
LIAIMMPLLLLLLAGWVIVWRVVNQQLNPLTDLADSLNRQTHTSLEPVDETFVPVEIRPLTGALNGLLDRLKSALDAQRK
FIADAAHQLRTPLTAIKLHAEQAAIARDPQQTLAAVKELRAAADRAVRLSNQLLSLARAEPGEQAARFVNLDVASLAFDT
GAEWVPRALAVHVDLGFQRLDDPSNDHPLIARGNPVLLREVIANLLDNALKYVPPSRINGARITMTVAQVVVDGVAMAEV
AVEDNGPGVPLKQQPELFKRFFRGDGQGQSDSSVDGGAGLGLAIVHDIMALHRGSVHYEDAAEGGARFIVRLPVATGAVL
REPDPARETKKPAHAPVDL

Sequences:

>Translated_499_residues
MNYPAANSLRRQLLRRLAAPLSLLALMSGLIAYWLAWQYTQHVVDRSLADLATAISKQIQIAGPDAPITVPPLAQAMFSD
PVEQLVYRISNGETEIAGDPKLPLQGTNVRRMHYAYVFETQHEGTAVRVAQVRVDQPTGNPVVIEVGQPVHHRFRIAAEF
LIAIMMPLLLLLLAGWVIVWRVVNQQLNPLTDLADSLNRQTHTSLEPVDETFVPVEIRPLTGALNGLLDRLKSALDAQRK
FIADAAHQLRTPLTAIKLHAEQAAIARDPQQTLAAVKELRAAADRAVRLSNQLLSLARAEPGEQAARFVNLDVASLAFDT
GAEWVPRALAVHVDLGFQRLDDPSNDHPLIARGNPVLLREVIANLLDNALKYVPPSRINGARITMTVAQVVVDGVAMAEV
AVEDNGPGVPLKQQPELFKRFFRGDGQGQSDSSVDGGAGLGLAIVHDIMALHRGSVHYEDAAEGGARFIVRLPVATGAVL
REPDPARETKKPAHAPVDL
>Mature_499_residues
MNYPAANSLRRQLLRRLAAPLSLLALMSGLIAYWLAWQYTQHVVDRSLADLATAISKQIQIAGPDAPITVPPLAQAMFSD
PVEQLVYRISNGETEIAGDPKLPLQGTNVRRMHYAYVFETQHEGTAVRVAQVRVDQPTGNPVVIEVGQPVHHRFRIAAEF
LIAIMMPLLLLLLAGWVIVWRVVNQQLNPLTDLADSLNRQTHTSLEPVDETFVPVEIRPLTGALNGLLDRLKSALDAQRK
FIADAAHQLRTPLTAIKLHAEQAAIARDPQQTLAAVKELRAAADRAVRLSNQLLSLARAEPGEQAARFVNLDVASLAFDT
GAEWVPRALAVHVDLGFQRLDDPSNDHPLIARGNPVLLREVIANLLDNALKYVPPSRINGARITMTVAQVVVDGVAMAEV
AVEDNGPGVPLKQQPELFKRFFRGDGQGQSDSSVDGGAGLGLAIVHDIMALHRGSVHYEDAAEGGARFIVRLPVATGAVL
REPDPARETKKPAHAPVDL

Specific function: Member of a two-component regulatory system qseB/qseC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=470, Percent_Identity=28.5106382978723, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI1790551, Length=327, Percent_Identity=31.8042813455657, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1786783, Length=305, Percent_Identity=29.1803278688525, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790346, Length=268, Percent_Identity=28.7313432835821, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786600, Length=248, Percent_Identity=33.0645161290323, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788393, Length=261, Percent_Identity=27.5862068965517, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI145693157, Length=243, Percent_Identity=25.9259259259259, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1786912, Length=257, Percent_Identity=31.5175097276265, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1788713, Length=265, Percent_Identity=24.5283018867925, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789149, Length=364, Percent_Identity=22.8021978021978, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1790861, Length=313, Percent_Identity=28.1150159744409, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87082128, Length=313, Percent_Identity=25.8785942492013, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54310; Mature: 54310

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYPAANSLRRQLLRRLAAPLSLLALMSGLIAYWLAWQYTQHVVDRSLADLATAISKQIQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEE
IAGPDAPITVPPLAQAMFSDPVEQLVYRISNGETEIAGDPKLPLQGTNVRRMHYAYVFET
EECCCCCCCCCHHHHHHHHCHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEEEEEEEE
QHEGTAVRVAQVRVDQPTGNPVVIEVGQPVHHRFRIAAEFLIAIMMPLLLLLLAGWVIVW
CCCCCEEEEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVVNQQLNPLTDLADSLNRQTHTSLEPVDETFVPVEIRPLTGALNGLLDRLKSALDAQRK
HHHHHHCCHHHHHHHHHCHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
FIADAAHQLRTPLTAIKLHAEQAAIARDPQQTLAAVKELRAAADRAVRLSNQLLSLARAE
HHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGEQAARFVNLDVASLAFDTGAEWVPRALAVHVDLGFQRLDDPSNDHPLIARGNPVLLRE
CHHHHHHHHCCHHHHHHHHCCCHHHHHHHEEEEECCHHHCCCCCCCCCEEECCCHHHHHH
VIANLLDNALKYVPPSRINGARITMTVAQVVVDGVAMAEVAVEDNGPGVPLKQQPELFKR
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHH
FFRGDGQGQSDSSVDGGAGLGLAIVHDIMALHRGSVHYEDAAEGGARFIVRLPVATGAVL
HHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEEEECCCCCHHH
REPDPARETKKPAHAPVDL
CCCCCCHHCCCCCCCCCCC
>Mature Secondary Structure
MNYPAANSLRRQLLRRLAAPLSLLALMSGLIAYWLAWQYTQHVVDRSLADLATAISKQIQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEE
IAGPDAPITVPPLAQAMFSDPVEQLVYRISNGETEIAGDPKLPLQGTNVRRMHYAYVFET
EECCCCCCCCCHHHHHHHHCHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEEEEEEEE
QHEGTAVRVAQVRVDQPTGNPVVIEVGQPVHHRFRIAAEFLIAIMMPLLLLLLAGWVIVW
CCCCCEEEEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVVNQQLNPLTDLADSLNRQTHTSLEPVDETFVPVEIRPLTGALNGLLDRLKSALDAQRK
HHHHHHCCHHHHHHHHHCHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
FIADAAHQLRTPLTAIKLHAEQAAIARDPQQTLAAVKELRAAADRAVRLSNQLLSLARAE
HHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGEQAARFVNLDVASLAFDTGAEWVPRALAVHVDLGFQRLDDPSNDHPLIARGNPVLLRE
CHHHHHHHHCCHHHHHHHHCCCHHHHHHHEEEEECCHHHCCCCCCCCCEEECCCHHHHHH
VIANLLDNALKYVPPSRINGARITMTVAQVVVDGVAMAEVAVEDNGPGVPLKQQPELFKR
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHH
FFRGDGQGQSDSSVDGGAGLGLAIVHDIMALHRGSVHYEDAAEGGARFIVRLPVATGAVL
HHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEEEECCCCCHHH
REPDPARETKKPAHAPVDL
CCCCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]