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The map label for this gene is 186477799

Identifier: 186477799

GI number: 186477799

Start: 3432195

End: 3432446

Strand: Direct

Name: 186477799

Synonym: Bphy_3055

Alternate gene names: NA

Gene position: 3432195-3432446 (Clockwise)

Preceding gene: 186477797

Following gene: 186477801

Centisome position: 98.65

GC content: 55.95

Gene sequence:

>252_bases
GTGCGAGCCAGATCGCGCAACGCACCGGGCTGCAGAACGTCGAGGGGCCACGACGCGATCAGTCGGCAATTCAAGTTCGC
CGACTTCAACGAAGCATTCCGCTTCAAGACGCGCGTCGCGATCAAGGCTCAGCAGATCGACCATCACCCTTTCAACGTCT
ACAGTAACGTCGACATCACGCTATCGACGCACGATGCGAATAGAATTTCCGAGCGCGCACCATTTATCGATGAAGTGGCA
GCTGAAAACTGA

Upstream 100 bases:

>100_bases
TTTCGATGCGGGATTATCGCATTCACCTTGGTTCGGAAAACTTGCGTCCCACGCAGCTTCTAAGGTGACACGATGATCGA
GAAACTTCCCTCGGAAGAAC

Downstream 100 bases:

>100_bases
TGTGAGGCGTTGATTAGACGAAAGCCGGTTGCGCTTTGAAAAGTCCGGAGAAAACCCGTGGCGAAAGCGTATTGCAGGTA
ATCAGGCCACCAAACCTTCA

Product: transcriptional coactivator/pterin dehydratase

Products: NA

Alternate protein names: PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD [H]

Number of amino acids: Translated: 83; Mature: 83

Protein sequence:

>83_residues
MRARSRNAPGCRTSRGHDAISRQFKFADFNEAFRFKTRVAIKAQQIDHHPFNVYSNVDITLSTHDANRISERAPFIDEVA
AEN

Sequences:

>Translated_83_residues
MRARSRNAPGCRTSRGHDAISRQFKFADFNEAFRFKTRVAIKAQQIDHHPFNVYSNVDITLSTHDANRISERAPFIDEVA
AEN
>Mature_83_residues
MRARSRNAPGCRTSRGHDAISRQFKFADFNEAFRFKTRVAIKAQQIDHHPFNVYSNVDITLSTHDANRISERAPFIDEVA
AEN

Specific function: Unknown

COG id: COG2154

COG function: function code H; Pterin-4a-carbinolamine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pterin-4-alpha-carbinolamine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI4557831, Length=80, Percent_Identity=53.75, Blast_Score=82, Evalue=1e-16,
Organism=Homo sapiens, GI134133240, Length=80, Percent_Identity=42.5, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115533705, Length=77, Percent_Identity=51.9480519480519, Blast_Score=83, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45549100, Length=65, Percent_Identity=50.7692307692308, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001533 [H]

Pfam domain/function: PF01329 Pterin_4a [H]

EC number: =4.2.1.96 [H]

Molecular weight: Translated: 9520; Mature: 9520

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRARSRNAPGCRTSRGHDAISRQFKFADFNEAFRFKTRVAIKAQQIDHHPFNVYSNVDIT
CCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHEEHHHEEEEECCCCCCCCEEECCCEEE
LSTHDANRISERAPFIDEVAAEN
EECCCCHHHHHCCCCHHHHCCCC
>Mature Secondary Structure
MRARSRNAPGCRTSRGHDAISRQFKFADFNEAFRFKTRVAIKAQQIDHHPFNVYSNVDIT
CCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHEEHHHEEEEECCCCCCCCEEECCCEEE
LSTHDANRISERAPFIDEVAAEN
EECCCCHHHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA