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The map label for this gene is dppB [H]

Identifier: 186477661

GI number: 186477661

Start: 3267450

End: 3268463

Strand: Reverse

Name: dppB [H]

Synonym: Bphy_2913

Alternate gene names: 186477661

Gene position: 3268463-3267450 (Counterclockwise)

Preceding gene: 186477662

Following gene: 186477660

Centisome position: 93.94

GC content: 63.61

Gene sequence:

>1014_bases
ATGTTCCGATTCGTTTTGCGCCGCATCGGGATGGTCATACCGACGTTCATCGGTATCACGATCCTCGCGTTCGCGCTTAT
TCACCTGATTCCGGGCGACCCCATCGAAGTGATGATGGGCGAGCGCGGCGTCGACCCGGCCATGCACGCAGCCGCGATGC
ATCGACTGGGGCTCGACGAGCCGCTGCCCGTCCAGTACCTCCATTACGTCGGCCACGCGCTGCAAGGGAACCTCGGCACG
TCGATCATCACCAACACCAGTGTGATGGACGAATTCGTGGCCCGTTTCCCCGCCACCGTCGAACTGTCGATCTGCGCGAT
GCTGTTCGCGTTGATCGTCGGGCTGCCGGCGGGCGTGTTCGCGGCGCTGCGGCGCGGCTCAGTGGTCGATCATGGCGTGA
TGGGCACCGCGCTGACCGGCTACTCGATGCCGATCTTCTGGTGGGGCTTGATCCTCATCATGTTCTTCTCGTCCAAGCTC
GGCTGGACGCCCGTCTCCGGCCGCATCGCCGTCGAGTACGACATTCCGCACGTGACCGGCTTTCTGCTGATCGACTCGCT
GCTGCCCGGCACGGATGAAGGCTCGTTCCGCTCGGCGCTGTCTCACCTGATCCTGCCGTCGATCGTGCTCGGCACCATCC
CCCTCGCGGTGGTCGCGCGAATGACGCGTTCGTCGATGCTCGAAGTGCTGCGCGAAGACTACATCCGCACGGCGCGTGCG
AAGGGTTTGTCGCCGGGACGCGTGATCGTCGTGCATGCGCTGCGTAATGCGCTGATCCCTGTCGTGACCGTGATCGGTCT
GCAGGTCGGCACGCTGCTTGCGGGCGCCGTGCTGACGGAAACCTTGTTCTCATGGCCGGGCATCGGGAAATGGCTGATCG
ATGCGATCGGCCGGCGCGACTATCCCGTCGTGCAGGGCGGTATCCTGATGATCGCGACGCTCGTGATTGTCGTGAACCTC
GTCGTCGACTTGCTGTACGGCGTGCTCAACCCACGCATTCGCCATACGAGGTAA

Upstream 100 bases:

>100_bases
TTCGTTCGGTTAGAAGACTGGTCGAAATGGTCCGGCGACCGGGGTCACGAGCCCTCGTCGCCGGTTGCGTTTTTTCTCAC
CAAGACCATAGGGACGAACC

Downstream 100 bases:

>100_bases
AAGGAATATGTACCCCCACGCTCACATTTGTTCGCTTCCCCCCAAGCGGGCGCATGCCTGCCTTGAGGCGGCTCGGCGGG
AGGCATGATGGCCGACATCC

Product: nickel-transporting ATPase

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MFRFVLRRIGMVIPTFIGITILAFALIHLIPGDPIEVMMGERGVDPAMHAAAMHRLGLDEPLPVQYLHYVGHALQGNLGT
SIITNTSVMDEFVARFPATVELSICAMLFALIVGLPAGVFAALRRGSVVDHGVMGTALTGYSMPIFWWGLILIMFFSSKL
GWTPVSGRIAVEYDIPHVTGFLLIDSLLPGTDEGSFRSALSHLILPSIVLGTIPLAVVARMTRSSMLEVLREDYIRTARA
KGLSPGRVIVVHALRNALIPVVTVIGLQVGTLLAGAVLTETLFSWPGIGKWLIDAIGRRDYPVVQGGILMIATLVIVVNL
VVDLLYGVLNPRIRHTR

Sequences:

>Translated_337_residues
MFRFVLRRIGMVIPTFIGITILAFALIHLIPGDPIEVMMGERGVDPAMHAAAMHRLGLDEPLPVQYLHYVGHALQGNLGT
SIITNTSVMDEFVARFPATVELSICAMLFALIVGLPAGVFAALRRGSVVDHGVMGTALTGYSMPIFWWGLILIMFFSSKL
GWTPVSGRIAVEYDIPHVTGFLLIDSLLPGTDEGSFRSALSHLILPSIVLGTIPLAVVARMTRSSMLEVLREDYIRTARA
KGLSPGRVIVVHALRNALIPVVTVIGLQVGTLLAGAVLTETLFSWPGIGKWLIDAIGRRDYPVVQGGILMIATLVIVVNL
VVDLLYGVLNPRIRHTR
>Mature_337_residues
MFRFVLRRIGMVIPTFIGITILAFALIHLIPGDPIEVMMGERGVDPAMHAAAMHRLGLDEPLPVQYLHYVGHALQGNLGT
SIITNTSVMDEFVARFPATVELSICAMLFALIVGLPAGVFAALRRGSVVDHGVMGTALTGYSMPIFWWGLILIMFFSSKL
GWTPVSGRIAVEYDIPHVTGFLLIDSLLPGTDEGSFRSALSHLILPSIVLGTIPLAVVARMTRSSMLEVLREDYIRTARA
KGLSPGRVIVVHALRNALIPVVTVIGLQVGTLLAGAVLTETLFSWPGIGKWLIDAIGRRDYPVVQGGILMIATLVIVVNL
VVDLLYGVLNPRIRHTR

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=340, Percent_Identity=64.1176470588235, Blast_Score=444, Evalue=1e-126,
Organism=Escherichia coli, GI1787053, Length=336, Percent_Identity=40.4761904761905, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1787761, Length=317, Percent_Identity=47.9495268138801, Blast_Score=238, Evalue=5e-64,
Organism=Escherichia coli, GI1787550, Length=275, Percent_Identity=40.3636363636364, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1789888, Length=337, Percent_Identity=34.4213649851632, Blast_Score=204, Evalue=6e-54,
Organism=Escherichia coli, GI1787497, Length=336, Percent_Identity=34.2261904761905, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI1788504, Length=372, Percent_Identity=26.0752688172043, Blast_Score=134, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36570; Mature: 36570

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRFVLRRIGMVIPTFIGITILAFALIHLIPGDPIEVMMGERGVDPAMHAAAMHRLGLDE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCC
PLPVQYLHYVGHALQGNLGTSIITNTSVMDEFVARFPATVELSICAMLFALIVGLPAGVF
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHH
AALRRGSVVDHGVMGTALTGYSMPIFWWGLILIMFFSSKLGWTPVSGRIAVEYDIPHVTG
HHHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHH
FLLIDSLLPGTDEGSFRSALSHLILPSIVLGTIPLAVVARMTRSSMLEVLREDYIRTARA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGLSPGRVIVVHALRNALIPVVTVIGLQVGTLLAGAVLTETLFSWPGIGKWLIDAIGRRD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCC
YPVVQGGILMIATLVIVVNLVVDLLYGVLNPRIRHTR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MFRFVLRRIGMVIPTFIGITILAFALIHLIPGDPIEVMMGERGVDPAMHAAAMHRLGLDE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCC
PLPVQYLHYVGHALQGNLGTSIITNTSVMDEFVARFPATVELSICAMLFALIVGLPAGVF
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHH
AALRRGSVVDHGVMGTALTGYSMPIFWWGLILIMFFSSKLGWTPVSGRIAVEYDIPHVTG
HHHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHH
FLLIDSLLPGTDEGSFRSALSHLILPSIVLGTIPLAVVARMTRSSMLEVLREDYIRTARA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGLSPGRVIVVHALRNALIPVVTVIGLQVGTLLAGAVLTETLFSWPGIGKWLIDAIGRRD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCC
YPVVQGGILMIATLVIVVNLVVDLLYGVLNPRIRHTR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]