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The map label for this gene is dppC [H]

Identifier: 186477660

GI number: 186477660

Start: 3266445

End: 3267362

Strand: Reverse

Name: dppC [H]

Synonym: Bphy_2912

Alternate gene names: 186477660

Gene position: 3267362-3266445 (Counterclockwise)

Preceding gene: 186477661

Following gene: 186477659

Centisome position: 93.91

GC content: 65.36

Gene sequence:

>918_bases
ATGGCCGACATCCAAAATACAGTCCCCCAGGCAGTGACGCCGCCGAGCGGCCGCGCCATTGCCGCTCGCGAATTCTGGTC
TAATTTCTCGCGCAATCGCGGTGCGGTTACCGCGGGCATCATCGTGCTGGTGCTGATCTTCGTCGCGATTTTCGCGCCGC
TGATCGCGCCGCACAGCCCGATCGAGCAATATCGCGATTCCGTGAAGATTCCGCCCGCCTGGCTCGATGGCGGCAACTGG
AAATTCATTCTCGGCACCGACGAAGCAGGCCGCGACATCCTCTCGCGCCTGATGTACGGCGCGCGTCTGTCGTTCTGGAT
TGGCTTCGTGTCCGTGATCCTCGCGCTGATTCCCGGCATCGTGCTCGGTCTCATCGCCGCGTTCTTCGAGAAGTGGGCCG
ACACGCCGATCATGCGCATCATGGACGTGCTGCTCGCGCTGCCGTCGCTGCTGCTCGCGGTGGCCGTCGTCGCCATCATC
GGTCCTGGCCTCGTGAACACGATGCTTGCGATCGCGATCGTCGCGCTGCCGGGTTATGTGCGTCTGACGCGCGCGTCGGC
GCTCGGCGAACTGCACAAGGAATACGTGATGGCCTCGCGCGTCGCGGGTGCCGGCACGGTCCGCCTGATGTTCTCGCAGG
TGCTGCCGAACTGCACGGCGCCGCTGATCGTGCAGGCCACGCTCGGCTTTTCGTCGGCGATTCTCGATGCCGCCGCGCTC
GGCTTCCTCGGCCTCGGCGTGCAACCGCCGTCGGCGGAGTGGGGCGCGATGCTCGCATCGGCACGCGACTACATCGACAG
CGCATGGTGGATCGTCACCATGCCCGGTCTCGCCATCCTGATCTCGGTGCTCTCGATCAACCTGCTCGGCGACGGGCTGC
GCGACGCACTCGACCCGAAACTCAAACGGCTGGCCTGA

Upstream 100 bases:

>100_bases
CCATACGAGGTAAAAGGAATATGTACCCCCACGCTCACATTTGTTCGCTTCCCCCCAAGCGGGCGCATGCCTGCCTTGAG
GCGGCTCGGCGGGAGGCATG

Downstream 100 bases:

>100_bases
CATGAGCAACGGTAACCTATTGACCATCCGCAATCTTGCGGTGAACTTCGGCGGCCTGCCCGCCGTGGATCGAATCAATC
TGAACGTGGCGCCGGGTGAA

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MADIQNTVPQAVTPPSGRAIAAREFWSNFSRNRGAVTAGIIVLVLIFVAIFAPLIAPHSPIEQYRDSVKIPPAWLDGGNW
KFILGTDEAGRDILSRLMYGARLSFWIGFVSVILALIPGIVLGLIAAFFEKWADTPIMRIMDVLLALPSLLLAVAVVAII
GPGLVNTMLAIAIVALPGYVRLTRASALGELHKEYVMASRVAGAGTVRLMFSQVLPNCTAPLIVQATLGFSSAILDAAAL
GFLGLGVQPPSAEWGAMLASARDYIDSAWWIVTMPGLAILISVLSINLLGDGLRDALDPKLKRLA

Sequences:

>Translated_305_residues
MADIQNTVPQAVTPPSGRAIAAREFWSNFSRNRGAVTAGIIVLVLIFVAIFAPLIAPHSPIEQYRDSVKIPPAWLDGGNW
KFILGTDEAGRDILSRLMYGARLSFWIGFVSVILALIPGIVLGLIAAFFEKWADTPIMRIMDVLLALPSLLLAVAVVAII
GPGLVNTMLAIAIVALPGYVRLTRASALGELHKEYVMASRVAGAGTVRLMFSQVLPNCTAPLIVQATLGFSSAILDAAAL
GFLGLGVQPPSAEWGAMLASARDYIDSAWWIVTMPGLAILISVLSINLLGDGLRDALDPKLKRLA
>Mature_304_residues
ADIQNTVPQAVTPPSGRAIAAREFWSNFSRNRGAVTAGIIVLVLIFVAIFAPLIAPHSPIEQYRDSVKIPPAWLDGGNWK
FILGTDEAGRDILSRLMYGARLSFWIGFVSVILALIPGIVLGLIAAFFEKWADTPIMRIMDVLLALPSLLLAVAVVAIIG
PGLVNTMLAIAIVALPGYVRLTRASALGELHKEYVMASRVAGAGTVRLMFSQVLPNCTAPLIVQATLGFSSAILDAAALG
FLGLGVQPPSAEWGAMLASARDYIDSAWWIVTMPGLAILISVLSINLLGDGLRDALDPKLKRLA

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=281, Percent_Identity=60.4982206405694, Blast_Score=308, Evalue=2e-85,
Organism=Escherichia coli, GI1787054, Length=280, Percent_Identity=42.8571428571429, Blast_Score=221, Evalue=5e-59,
Organism=Escherichia coli, GI1787760, Length=265, Percent_Identity=45.6603773584906, Blast_Score=218, Evalue=4e-58,
Organism=Escherichia coli, GI1787549, Length=293, Percent_Identity=44.0273037542662, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1789889, Length=226, Percent_Identity=39.8230088495575, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1787498, Length=286, Percent_Identity=30.4195804195804, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1788505, Length=226, Percent_Identity=27.4336283185841, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32491; Mature: 32360

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADIQNTVPQAVTPPSGRAIAAREFWSNFSRNRGAVTAGIIVLVLIFVAIFAPLIAPHSP
CCCCHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCH
IEQYRDSVKIPPAWLDGGNWKFILGTDEAGRDILSRLMYGARLSFWIGFVSVILALIPGI
HHHHHHCCCCCCCEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLGLIAAFFEKWADTPIMRIMDVLLALPSLLLAVAVVAIIGPGLVNTMLAIAIVALPGYV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHH
RLTRASALGELHKEYVMASRVAGAGTVRLMFSQVLPNCTAPLIVQATLGFSSAILDAAAL
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHCHHHHHHHHHHH
GFLGLGVQPPSAEWGAMLASARDYIDSAWWIVTMPGLAILISVLSINLLGDGLRDALDPK
HHHHCCCCCCCCHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCHH
LKRLA
HHHCC
>Mature Secondary Structure 
ADIQNTVPQAVTPPSGRAIAAREFWSNFSRNRGAVTAGIIVLVLIFVAIFAPLIAPHSP
CCCHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCH
IEQYRDSVKIPPAWLDGGNWKFILGTDEAGRDILSRLMYGARLSFWIGFVSVILALIPGI
HHHHHHCCCCCCCEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLGLIAAFFEKWADTPIMRIMDVLLALPSLLLAVAVVAIIGPGLVNTMLAIAIVALPGYV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHH
RLTRASALGELHKEYVMASRVAGAGTVRLMFSQVLPNCTAPLIVQATLGFSSAILDAAAL
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHCHHHHHHHHHHH
GFLGLGVQPPSAEWGAMLASARDYIDSAWWIVTMPGLAILISVLSINLLGDGLRDALDPK
HHHHCCCCCCCCHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCHH
LKRLA
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]