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The map label for this gene is creB [C]

Identifier: 186477467

GI number: 186477467

Start: 3074668

End: 3075414

Strand: Direct

Name: creB [C]

Synonym: Bphy_2719

Alternate gene names: 186477467

Gene position: 3074668-3075414 (Clockwise)

Preceding gene: 186477462

Following gene: 186477468

Centisome position: 88.37

GC content: 63.19

Gene sequence:

>747_bases
ATGCGAATCGCCCTTATTGAGCCTGACCTCCGGCATGCGGAAATCGTCGGCCGGCTACTGCTTGCCGGGGGTCATGCCTG
CCATCATTTCGCCGCCAGTGCACCTTTTCTCGCGGGCGCCGAACACGAATTCTTCGATCTCCTCGTCACCGACGCATTCT
GCGGCGACGCCGCAGCGGAAGACGTCATCGCGCGCGCGCGCAAGGTTCTGCCCGGCCTGCCCGTCGTGGCCCTGATGAGC
GCGCCGCGCGAAAGCGAACTCGTCGCGATGCTGCAGGCAGGGGCCGACGACTGCCTGTCCAAGCCCGTACGCGGTCCGGA
AATGCTGGCGCGCATCGAAGCGTTGATGCGCCGGGCGGGAATACGCCGCCCGCGCAACCGTGCGCGCGAAATGTTCGGCG
AGTACGCATTCGATGTGGGCCGCTCCAGCGTCAGCTTTCGGGGACAAAGCATCACGATGACGCCGAAGGAACTGCAGTTC
GCGCTACTGCTGTTTACCAATATGTCGAGACCTGTTTCAAGGGCGCACATCCTCGAAACAGTCTGGTCCCGGCGCCGCGA
CGTAAGGTCGCGCACGCTCGACACGCACGCATCACGCATCCGCACCAAGCTCGAACTGCGGCCCGAATTCGGCTACACGC
TGACGCCGCTGTATGGCTACGGCTACCGTCTCGACCGGATTCCCGTTGAGAATCCGGATACCACGGATAAACCCCCGCCG
GCTGAAAGAATCGTGGAAACGCTATAA

Upstream 100 bases:

>100_bases
TCGGCACGGCTTTCTGCGTAGCGGTTGAGTTTAGGGGCCGGGGTAAGGTTAAGCAAGCTGAAAGCCTCCGCGCCAGATCG
CTGCGCCCATCCCACCATCA

Downstream 100 bases:

>100_bases
TATTGGGCTTAACCATAGCCCCAATACGTCGCGCCAAAAACGCCGTAGCGTCCCCGTGCAACTGCTAACGATCGGAATCA
ATCACCACACAGCGCCTGTC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MRIALIEPDLRHAEIVGRLLLAGGHACHHFAASAPFLAGAEHEFFDLLVTDAFCGDAAAEDVIARARKVLPGLPVVALMS
APRESELVAMLQAGADDCLSKPVRGPEMLARIEALMRRAGIRRPRNRAREMFGEYAFDVGRSSVSFRGQSITMTPKELQF
ALLLFTNMSRPVSRAHILETVWSRRRDVRSRTLDTHASRIRTKLELRPEFGYTLTPLYGYGYRLDRIPVENPDTTDKPPP
AERIVETL

Sequences:

>Translated_248_residues
MRIALIEPDLRHAEIVGRLLLAGGHACHHFAASAPFLAGAEHEFFDLLVTDAFCGDAAAEDVIARARKVLPGLPVVALMS
APRESELVAMLQAGADDCLSKPVRGPEMLARIEALMRRAGIRRPRNRAREMFGEYAFDVGRSSVSFRGQSITMTPKELQF
ALLLFTNMSRPVSRAHILETVWSRRRDVRSRTLDTHASRIRTKLELRPEFGYTLTPLYGYGYRLDRIPVENPDTTDKPPP
AERIVETL
>Mature_248_residues
MRIALIEPDLRHAEIVGRLLLAGGHACHHFAASAPFLAGAEHEFFDLLVTDAFCGDAAAEDVIARARKVLPGLPVVALMS
APRESELVAMLQAGADDCLSKPVRGPEMLARIEALMRRAGIRRPRNRAREMFGEYAFDVGRSSVSFRGQSITMTPKELQF
ALLLFTNMSRPVSRAHILETVWSRRRDVRSRTLDTHASRIRTKLELRPEFGYTLTPLYGYGYRLDRIPVENPDTTDKPPP
AERIVETL

Specific function: Member Of The Two-Component Regulatory System Crec/Creb Involved In Catabolic Regulation. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=26.431718061674, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790552, Length=207, Percent_Identity=27.536231884058, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=29.0178571428571, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=23.5555555555556, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=25, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI2367329, Length=154, Percent_Identity=31.8181818181818, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1786784, Length=236, Percent_Identity=22.8813559322034, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786599, Length=133, Percent_Identity=33.8345864661654, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI87082012, Length=205, Percent_Identity=27.8048780487805, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1786911, Length=180, Percent_Identity=27.7777777777778, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27746; Mature: 27746

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIALIEPDLRHAEIVGRLLLAGGHACHHFAASAPFLAGAEHEFFDLLVTDAFCGDAAAE
CEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHH
DVIARARKVLPGLPVVALMSAPRESELVAMLQAGADDCLSKPVRGPEMLARIEALMRRAG
HHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHC
IRRPRNRAREMFGEYAFDVGRSSVSFRGQSITMTPKELQFALLLFTNMSRPVSRAHILET
CCCHHHHHHHHHHHHHHHHCCCCCEECCCEEEECHHHHHHHHHHHHCCCCHHHHHHHHHH
VWSRRRDVRSRTLDTHASRIRTKLELRPEFGYTLTPLYGYGYRLDRIPVENPDTTDKPPP
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEECCHHCCCEEECCCCCCCCCCCCCCCC
AERIVETL
HHHHHHCC
>Mature Secondary Structure
MRIALIEPDLRHAEIVGRLLLAGGHACHHFAASAPFLAGAEHEFFDLLVTDAFCGDAAAE
CEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHH
DVIARARKVLPGLPVVALMSAPRESELVAMLQAGADDCLSKPVRGPEMLARIEALMRRAG
HHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHC
IRRPRNRAREMFGEYAFDVGRSSVSFRGQSITMTPKELQFALLLFTNMSRPVSRAHILET
CCCHHHHHHHHHHHHHHHHCCCCCEECCCEEEECHHHHHHHHHHHHCCCCHHHHHHHHHH
VWSRRRDVRSRTLDTHASRIRTKLELRPEFGYTLTPLYGYGYRLDRIPVENPDTTDKPPP
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEECCHHCCCEEECCCCCCCCCCCCCCCC
AERIVETL
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1554697 [H]