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The map label for this gene is mraY [H]

Identifier: 186477424

GI number: 186477424

Start: 3019068

End: 3020237

Strand: Reverse

Name: mraY [H]

Synonym: Bphy_2676

Alternate gene names: 186477424

Gene position: 3020237-3019068 (Counterclockwise)

Preceding gene: 186477425

Following gene: 186477423

Centisome position: 86.81

GC content: 60.77

Gene sequence:

>1170_bases
ATGTTACTGGCGCTGGCGCAATGGCTGCAGAACGACGTAGGCTTTTTGCGCGTGTTCAGTTATCTGACGTTTCGTGCTGT
CGCGGCGACGATCACCGCGCTGCTGATCGGTCTCGTCTGCGGCCCGTGGGTGATCCGCAAGCTGACGCAGATGAAGGTCG
GCCAGGCGGTGCGCAAGGACGGACCGCAAACGCATCTCGTGAAATCGGGCACGCCGACGATGGGCGGCGTGCTGATCCTC
ATCGGCATCGCCGTGTCCACGCTGCTGTGGGCCGATTTGACCAACCGTTTCATCTGGATCGTGATGCTGGTCACGTTCGG
CTTCGGCGTGATCGGCTGGGTCGACGACTACCGCAAGGTCGTCTACAAGGACCCGCGCGGCATGTCGTCGCGCGAAAAGT
ATTTCTGGCAGTCGTTGATTGGCCTGTTTGCGGCCGTGTATCTCGCGTTCAGTGTGTCGGAAGCGAGCAATGTACGCGTG
TTTGACCTGTTCATGGCATGGGTGAGAAGCGGTCTGTCGATGGGGCTGCCCGCGCGCGCCGACCTGCTGCTGCCGTTCCT
CAAGTCGATGACCTATCCGCTCGGCGTGTGGGGCTTCATTGCGCTCACGTACCTCGTGATTGTCGGTTCGAGCAATGCGG
TGAATCTCACGGATGGTCTCGACGGCCTCGTGATCATGCCTGTGGTGCTGGTCGGCTCGTCGCTCGGGGTGTTCGCGTAC
GTGATGGGCAGCGCCGTCTATTCGAAATATCTGCTGTTCCCCCACATCGCGGGCGCCGGCGAAATGCTGATCTTCTGCTC
GGCGATGGGTGGGGCAGGGCTCGCCTTCCTCTGGTTCAACACGCACCCGGCGCAGGTGTTCATGGGCGACGTCGGTGCGC
TCGCGCTCGGCGGCGCGCTCGGCACGATTGCTGTGATCGTGCGTCAGGAAATCGTGCTGTTCATCATGGGCGGGATTTTC
GTCGCCGAGACGGTGTCGGTAATGTTGCAGGTCACGTGGTTCAAGTTCACGAAGGCACGTTTCGGTGAAGGCCGCCGCAT
CTTCAAGATGGCGCCGCTGCATCACCACTTCGAATTGTCGGGCTGGAAAGAAACGCAGGTGGTCGTGCGCTTCTGGATCA
TCACGCTGATGTTGTGCCTGTTCGGTTTGTCCACGCTCAAGCTGCGTTAA

Upstream 100 bases:

>100_bases
GCTTCATGAAAATGGAACGCGTGGTGGACGCCGTTACGAGTCCACAACCCGCTGCACCGGGCACGGCGCCCGGCGCACAC
TGAAAGAGAAGGACAGGAGT

Downstream 100 bases:

>100_bases
GCCGCGGTTCGAGTCGCAATCAAAGTCGGATTCACAGTCGCAAGCAAGGGGAAGCAGTCGATGTTTGGCGAGAAGTTTCG
GGATCGGCAAAAGCCGATGG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MLLALAQWLQNDVGFLRVFSYLTFRAVAATITALLIGLVCGPWVIRKLTQMKVGQAVRKDGPQTHLVKSGTPTMGGVLIL
IGIAVSTLLWADLTNRFIWIVMLVTFGFGVIGWVDDYRKVVYKDPRGMSSREKYFWQSLIGLFAAVYLAFSVSEASNVRV
FDLFMAWVRSGLSMGLPARADLLLPFLKSMTYPLGVWGFIALTYLVIVGSSNAVNLTDGLDGLVIMPVVLVGSSLGVFAY
VMGSAVYSKYLLFPHIAGAGEMLIFCSAMGGAGLAFLWFNTHPAQVFMGDVGALALGGALGTIAVIVRQEIVLFIMGGIF
VAETVSVMLQVTWFKFTKARFGEGRRIFKMAPLHHHFELSGWKETQVVVRFWIITLMLCLFGLSTLKLR

Sequences:

>Translated_389_residues
MLLALAQWLQNDVGFLRVFSYLTFRAVAATITALLIGLVCGPWVIRKLTQMKVGQAVRKDGPQTHLVKSGTPTMGGVLIL
IGIAVSTLLWADLTNRFIWIVMLVTFGFGVIGWVDDYRKVVYKDPRGMSSREKYFWQSLIGLFAAVYLAFSVSEASNVRV
FDLFMAWVRSGLSMGLPARADLLLPFLKSMTYPLGVWGFIALTYLVIVGSSNAVNLTDGLDGLVIMPVVLVGSSLGVFAY
VMGSAVYSKYLLFPHIAGAGEMLIFCSAMGGAGLAFLWFNTHPAQVFMGDVGALALGGALGTIAVIVRQEIVLFIMGGIF
VAETVSVMLQVTWFKFTKARFGEGRRIFKMAPLHHHFELSGWKETQVVVRFWIITLMLCLFGLSTLKLR
>Mature_389_residues
MLLALAQWLQNDVGFLRVFSYLTFRAVAATITALLIGLVCGPWVIRKLTQMKVGQAVRKDGPQTHLVKSGTPTMGGVLIL
IGIAVSTLLWADLTNRFIWIVMLVTFGFGVIGWVDDYRKVVYKDPRGMSSREKYFWQSLIGLFAAVYLAFSVSEASNVRV
FDLFMAWVRSGLSMGLPARADLLLPFLKSMTYPLGVWGFIALTYLVIVGSSNAVNLTDGLDGLVIMPVVLVGSSLGVFAY
VMGSAVYSKYLLFPHIAGAGEMLIFCSAMGGAGLAFLWFNTHPAQVFMGDVGALALGGALGTIAVIVRQEIVLFIMGGIF
VAETVSVMLQVTWFKFTKARFGEGRRIFKMAPLHHHFELSGWKETQVVVRFWIITLMLCLFGLSTLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=389, Percent_Identity=52.4421593830334, Blast_Score=364, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 42780; Mature: 42780

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHHHHHHHHHHHHHHHHHCHHHHCCC
>Mature Secondary Structure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CCCHHHHHHHHHHHHHHHHHHCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA