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The map label for this gene is coaE [H]

Identifier: 186477406

GI number: 186477406

Start: 2999155

End: 2999757

Strand: Direct

Name: coaE [H]

Synonym: Bphy_2658

Alternate gene names: 186477406

Gene position: 2999155-2999757 (Clockwise)

Preceding gene: 186477405

Following gene: 186477407

Centisome position: 86.2

GC content: 63.18

Gene sequence:

>603_bases
ATGTTTGCTGTGGGATTGACGGGCGGCATCGGCAGCGGCAAATCTACGGTAGGCGATCTGTTCGCGAAACGTGGCGTGAC
ACTCGTCGATACCGACGTGATCGCGCATCGCGTGACCGCGCCGAATGGTCTCGCGATGCCGGCTATCGCGGCGGAGTTCG
GTGCATCGTTCGTCGCCGAAGACGGCTCGCTCGATCGCGCCCGCATGCGCGCGCTAGTCTTCAGCGACGAGAATGCGCGC
AAGCGGCTCGAAGCGATCACGCATCCGTTGATCCGGGCGGAGACCGAACGTCAGCGTCAACACGTGACGGGCCCGTACGT
GATCGTCGTCGTGCCGCTGCTCGTCGAATCCGGTAGCTGGAAAACGCGTGTGAACCGGGTGCTCGCCGTGGATTGCAGCG
TCGAGACGCAAATCGACCGGGTGATGCGGCGTAATGCGTTCACGCGCGAACAGGTGCTCGCGATCATTGCGCGTCAGGCG
ACGCGCGACGCACGCCTCGCTGCCGCCGACGACGTCATCGTCAACGACGGACGGTCGCTCGAACAACTCGACGTTGATGT
CGATCAGCTTCATCGCTCGTATGTTTCGCTCGCTGGCGCATAA

Upstream 100 bases:

>100_bases
GTTCGAAGAGCCGCTGCCATTCGGTCCGTTTCTCGCGGCGGGCGGCGCGGTGACGCTCTTTGTCGGCACGCCGCTTTACA
TGGCTTTGGGAGGCTGACGC

Downstream 100 bases:

>100_bases
GCCGTGAGCGATTCTGCTCGACGACGGTAATGTGGGCGCATATTGTCAGGAACGGCGTCTCGACGCAACGAATGGGCGCA
AATGGACGCAAAAATTGACG

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MFAVGLTGGIGSGKSTVGDLFAKRGVTLVDTDVIAHRVTAPNGLAMPAIAAEFGASFVAEDGSLDRARMRALVFSDENAR
KRLEAITHPLIRAETERQRQHVTGPYVIVVVPLLVESGSWKTRVNRVLAVDCSVETQIDRVMRRNAFTREQVLAIIARQA
TRDARLAAADDVIVNDGRSLEQLDVDVDQLHRSYVSLAGA

Sequences:

>Translated_200_residues
MFAVGLTGGIGSGKSTVGDLFAKRGVTLVDTDVIAHRVTAPNGLAMPAIAAEFGASFVAEDGSLDRARMRALVFSDENAR
KRLEAITHPLIRAETERQRQHVTGPYVIVVVPLLVESGSWKTRVNRVLAVDCSVETQIDRVMRRNAFTREQVLAIIARQA
TRDARLAAADDVIVNDGRSLEQLDVDVDQLHRSYVSLAGA
>Mature_200_residues
MFAVGLTGGIGSGKSTVGDLFAKRGVTLVDTDVIAHRVTAPNGLAMPAIAAEFGASFVAEDGSLDRARMRALVFSDENAR
KRLEAITHPLIRAETERQRQHVTGPYVIVVVPLLVESGSWKTRVNRVLAVDCSVETQIDRVMRRNAFTREQVLAIIARQA
TRDARLAAADDVIVNDGRSLEQLDVDVDQLHRSYVSLAGA

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=180, Percent_Identity=36.6666666666667, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI191252795, Length=180, Percent_Identity=36.6666666666667, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI110227607, Length=151, Percent_Identity=29.1390728476821, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI110227605, Length=151, Percent_Identity=29.1390728476821, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI110227603, Length=151, Percent_Identity=29.1390728476821, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI110227601, Length=151, Percent_Identity=29.1390728476821, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI205277394, Length=151, Percent_Identity=29.1390728476821, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1786292, Length=198, Percent_Identity=50, Blast_Score=175, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17554944, Length=182, Percent_Identity=33.5164835164835, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320402, Length=185, Percent_Identity=33.5135135135135, Blast_Score=83, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24644728, Length=180, Percent_Identity=29.4444444444444, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24658602, Length=178, Percent_Identity=29.7752808988764, Blast_Score=92, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 21705; Mature: 21705

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAVGLTGGIGSGKSTVGDLFAKRGVTLVDTDVIAHRVTAPNGLAMPAIAAEFGASFVAE
CEEEEECCCCCCCHHHHHHHHHHCCCEEEEHHHHHHHCCCCCCCCHHHHHHHHCCHHEEC
DGSLDRARMRALVFSDENARKRLEAITHPLIRAETERQRQHVTGPYVIVVVPLLVESGSW
CCCCCHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHCCCCC
KTRVNRVLAVDCSVETQIDRVMRRNAFTREQVLAIIARQATRDARLAAADDVIVNDGRSL
HHHHCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHCCCEEECCCCCH
EQLDVDVDQLHRSYVSLAGA
HHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MFAVGLTGGIGSGKSTVGDLFAKRGVTLVDTDVIAHRVTAPNGLAMPAIAAEFGASFVAE
CEEEEECCCCCCCHHHHHHHHHHCCCEEEEHHHHHHHCCCCCCCCHHHHHHHHCCHHEEC
DGSLDRARMRALVFSDENARKRLEAITHPLIRAETERQRQHVTGPYVIVVVPLLVESGSW
CCCCCHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHCCCCC
KTRVNRVLAVDCSVETQIDRVMRRNAFTREQVLAIIARQATRDARLAAADDVIVNDGRSL
HHHHCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHCCCEEECCCCCH
EQLDVDVDQLHRSYVSLAGA
HHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA