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The map label for this gene is tldD [H]

Identifier: 186477258

GI number: 186477258

Start: 2826318

End: 2827784

Strand: Direct

Name: tldD [H]

Synonym: Bphy_2509

Alternate gene names: 186477258

Gene position: 2826318-2827784 (Clockwise)

Preceding gene: 186477257

Following gene: 186477259

Centisome position: 81.24

GC content: 66.12

Gene sequence:

>1467_bases
ATGAACATCATCGAACCCAGCATCCGTAATCTCGCGACGGCCAAAGACGTGCTGCTCACGCCCTATGGCCTCGACGAAGC
CGTGCTGACCCGCACGCTCGCCGAAATCTTCACGCATCGCGTCGATTACGCCGACCTCTACTTCCAGACCACGCGCAGCG
AGGCGTGGAGCCTGGAGGAAGGCATTGTCAAGTCGGGCAGCTTCAGCATCGACCAGGGCGTCGGCGTGCGCGCCGTGTCG
GGCGACCGCACGGCGTTCGCGTATTCGGACGACCTGTCGCCCGAAGCGATCCGCCAGGCGGCAATCGCCACGCGCGCCAT
CGCGAAGGCAGGCGGCGGCAAGCAGAAAATCAAGGCAGCTTCCACACTGACGGGCGTGTCCGGGCGCGATCTGTATCTGC
CGTCCGATCCGCTGCATTCGCTCGACGCGACAGCGAAGGTCAAGCTGCTCGAGCGCATCGAGCAGATGGCGCGCGGCCGC
GATCCGCGCATCACGCAGGTGATGGCGGGTCTCGCGGGCGAATACGACGTCGTGCTGGTCGCGCGCAGCGACGGCGCGCT
GGCCGCGGACATCCGCCCGCTCGTGCGCGTGTCGGTGACGGTGATCGCCGAGCAGAACGGCCGCCGCGAAATCGGCAGCG
GCGGCGGCGGCGGACGCTTCGACTACGGCTACTTCAGCGACGACATCCTGTCGAAATACGTCGACGACGCCGTGCACGCG
GCGCTCGTCAATCTCGACGCGCGCCCGGCCCCCGCCGGCGCAATGACTGTCGTGCTCGGACCGGGCTGGCCCGGCGTGCT
GCTGCACGAAGCGATCGGCCACGGCCTCGAAGGCGACTTCAACCGCAAGGGCTCGTCGGCGTTCGCGGGGCGCATCGGCG
AACAGGTCGCGGCCAAGGGCGTGACGGTGGTCGACGACGGCACGCTGCCGAACCGCCGCGGCTCGCTGAACATCGACGAC
GAAGGCAACCCGACACAGTGCACGACGCTGATCGAGGACGGCATCCTGAAGGGCTACATTCAGGACACGCTGAATGCGCG
TCTGATGAAGATGCCCGTGACGGGAAACGCGCGCCGCGAATCGTACGCCGCGCTGCCCATGCCGCGCATGACGAACACCT
ACATGCTCAACGGCGACAAGGATCCGCAGGAAATCATCCAGTCGGTGAAGAACGGTCTGTATGCGGTGAACTTCGGCGGC
GGTCAGGTCGACATCACGAACGGCAAGTTCGTGTTCTCGGCGTCCGAGGCGTACATGATCGAGAACGGCAAGATCACGTA
TCCCGTCAAGGGCGCGACGCTGATCGGCAGCGGCCCCGAATCGCTCAAGTACGTGAGCATGATCGGCAACGACATGTCGC
TGGATACGGGTGTCGGCGTGTGCGGCAAGGAAGGCCAGAGCGTGCCCGTCGGCGTCGGTCAGCCGACGCTGCGCATCGAC
AAAATGACGGTCGGCGGCACGGTGTGA

Upstream 100 bases:

>100_bases
TGAAAGCGTTTGACCTGAATCGCACGCATTGAAAGTGCCGCCGCCGCTACCATGTGAGCGACGTGCACCAACCGACTACC
CAGAATCGAGCGAACTTCGC

Downstream 100 bases:

>100_bases
TCCGAATCGCTCGCTCGAATCGCGCATCGCGAGCGCCACTTGTGCGGGTTTCCCGCATTTTTGCAGCCTGCAGCTTGCCA
ACCGCGCAAACCTCGGGTTA

Product: peptidase U62 modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MNIIEPSIRNLATAKDVLLTPYGLDEAVLTRTLAEIFTHRVDYADLYFQTTRSEAWSLEEGIVKSGSFSIDQGVGVRAVS
GDRTAFAYSDDLSPEAIRQAAIATRAIAKAGGGKQKIKAASTLTGVSGRDLYLPSDPLHSLDATAKVKLLERIEQMARGR
DPRITQVMAGLAGEYDVVLVARSDGALAADIRPLVRVSVTVIAEQNGRREIGSGGGGGRFDYGYFSDDILSKYVDDAVHA
ALVNLDARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGEQVAAKGVTVVDDGTLPNRRGSLNIDD
EGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRESYAALPMPRMTNTYMLNGDKDPQEIIQSVKNGLYAVNFGG
GQVDITNGKFVFSASEAYMIENGKITYPVKGATLIGSGPESLKYVSMIGNDMSLDTGVGVCGKEGQSVPVGVGQPTLRID
KMTVGGTV

Sequences:

>Translated_488_residues
MNIIEPSIRNLATAKDVLLTPYGLDEAVLTRTLAEIFTHRVDYADLYFQTTRSEAWSLEEGIVKSGSFSIDQGVGVRAVS
GDRTAFAYSDDLSPEAIRQAAIATRAIAKAGGGKQKIKAASTLTGVSGRDLYLPSDPLHSLDATAKVKLLERIEQMARGR
DPRITQVMAGLAGEYDVVLVARSDGALAADIRPLVRVSVTVIAEQNGRREIGSGGGGGRFDYGYFSDDILSKYVDDAVHA
ALVNLDARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGEQVAAKGVTVVDDGTLPNRRGSLNIDD
EGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRESYAALPMPRMTNTYMLNGDKDPQEIIQSVKNGLYAVNFGG
GQVDITNGKFVFSASEAYMIENGKITYPVKGATLIGSGPESLKYVSMIGNDMSLDTGVGVCGKEGQSVPVGVGQPTLRID
KMTVGGTV
>Mature_488_residues
MNIIEPSIRNLATAKDVLLTPYGLDEAVLTRTLAEIFTHRVDYADLYFQTTRSEAWSLEEGIVKSGSFSIDQGVGVRAVS
GDRTAFAYSDDLSPEAIRQAAIATRAIAKAGGGKQKIKAASTLTGVSGRDLYLPSDPLHSLDATAKVKLLERIEQMARGR
DPRITQVMAGLAGEYDVVLVARSDGALAADIRPLVRVSVTVIAEQNGRREIGSGGGGGRFDYGYFSDDILSKYVDDAVHA
ALVNLDARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGEQVAAKGVTVVDDGTLPNRRGSLNIDD
EGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRESYAALPMPRMTNTYMLNGDKDPQEIIQSVKNGLYAVNFGG
GQVDITNGKFVFSASEAYMIENGKITYPVKGATLIGSGPESLKYVSMIGNDMSLDTGVGVCGKEGQSVPVGVGQPTLRID
KMTVGGTV

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=484, Percent_Identity=58.8842975206612, Blast_Score=548, Evalue=1e-157,
Organism=Escherichia coli, GI1790682, Length=452, Percent_Identity=25.2212389380531, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51733; Mature: 51733

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIIEPSIRNLATAKDVLLTPYGLDEAVLTRTLAEIFTHRVDYADLYFQTTRSEAWSLEE
CCCCCCHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCHHHEEEEECCCHHHHHHH
GIVKSGSFSIDQGVGVRAVSGDRTAFAYSDDLSPEAIRQAAIATRAIAKAGGGKQKIKAA
HHHCCCCCCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHEEHH
STLTGVSGRDLYLPSDPLHSLDATAKVKLLERIEQMARGRDPRITQVMAGLAGEYDVVLV
HHCCCCCCCEEECCCCCCHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEE
ARSDGALAADIRPLVRVSVTVIAEQNGRREIGSGGGGGRFDYGYFSDDILSKYVDDAVHA
ECCCCCEEHHCCCEEEEEEEEEECCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ALVNLDARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGEQVAAKG
HHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCC
VTVVDDGTLPNRRGSLNIDDEGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRE
CEEEECCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
SYAALPMPRMTNTYMLNGDKDPQEIIQSVKNGLYAVNFGGGQVDITNGKFVFSASEAYMI
CEECCCCCCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCEEEEECCEEEEECCCEEEE
ENGKITYPVKGATLIGSGPESLKYVSMIGNDMSLDTGVGVCGKEGQSVPVGVGQPTLRID
ECCEEEEEECCCEEECCCHHHHEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
KMTVGGTV
EEECCCCC
>Mature Secondary Structure
MNIIEPSIRNLATAKDVLLTPYGLDEAVLTRTLAEIFTHRVDYADLYFQTTRSEAWSLEE
CCCCCCHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCHHHEEEEECCCHHHHHHH
GIVKSGSFSIDQGVGVRAVSGDRTAFAYSDDLSPEAIRQAAIATRAIAKAGGGKQKIKAA
HHHCCCCCCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHEEHH
STLTGVSGRDLYLPSDPLHSLDATAKVKLLERIEQMARGRDPRITQVMAGLAGEYDVVLV
HHCCCCCCCEEECCCCCCHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEE
ARSDGALAADIRPLVRVSVTVIAEQNGRREIGSGGGGGRFDYGYFSDDILSKYVDDAVHA
ECCCCCEEHHCCCEEEEEEEEEECCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ALVNLDARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGEQVAAKG
HHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCC
VTVVDDGTLPNRRGSLNIDDEGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRE
CEEEECCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
SYAALPMPRMTNTYMLNGDKDPQEIIQSVKNGLYAVNFGGGQVDITNGKFVFSASEAYMI
CEECCCCCCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCEEEEECCEEEEECCCEEEE
ENGKITYPVKGATLIGSGPESLKYVSMIGNDMSLDTGVGVCGKEGQSVPVGVGQPTLRID
ECCEEEEEECCCEEECCCHHHHEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
KMTVGGTV
EEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]