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The map label for this gene is yafV [C]

Identifier: 186477257

GI number: 186477257

Start: 2825372

End: 2826220

Strand: Direct

Name: yafV [C]

Synonym: Bphy_2508

Alternate gene names: 186477257

Gene position: 2825372-2826220 (Clockwise)

Preceding gene: 186477256

Following gene: 186477258

Centisome position: 81.21

GC content: 66.78

Gene sequence:

>849_bases
ATGAGCGACCTGAACGCGCAGTCCGCCAAGTCCCCATCCCACGCCCGTCCGTTTCGCGTCGCCGCCTTGCAGATGGTGAG
CACGCCGGATCGCGACCGCAATCTCGCCGATGCCGAACGCCTGATCGCGCAAGCCGCCGCCGAAGGCGCGCAGCTCGTGC
TGCTGCCCGAGTATTTCTGCTTTATGGGCTTCAAGGACACCGACAAGCTCACGGTGCGCGAAGCGTACGGCGACGGCCCT
GTCCAGCGCTTTCTCGCCGATGCCGCGCGCCGGCATCAGGTCTGGATCATCGGCGGCACGCTGCCGTTGCAGGCGCCCGA
GGCAACCCGCGTGCTGAACACGACGCTCGTGTTCGACCCGCAGGGCAACGAGGCCGCGCGCTACGACAAGATCCATCTGT
TCAACTTCGAGAAAGGGGAGGAATCGTTCGACGAAGCACGCACGATCTGCCCCGGCGACACCGTCCGCACGTTCGATGCG
CCGTTCGGGCGCGTGGGCCTGTCCGTCTGCTACGATCTACGCTTTCCCGAACTGTACCGGCGCATGGGCGACTGCGCGCT
GATCGTCGTGCCGTCCGCATTCACGTACACGACGGGCCGCGCGCACTGGGAAACGCTGCTGCGCGCGCGGGCCGTCGAGA
ATCAGTGCTACGTGCTCGCCGCGGCGCAGGGCGGCAAGCATGAGAATGGCCGGCGCACGTGGGGCCATAGCATGCTGATC
GACCCGTGGGGCGAAATCATCGACGTGCGCGACGAAGGCGCGGGCGTTGTCGCGGGCAATATCGAGCGCTCGCGCATTGA
CGAAGTCCGGCAAAGCCTGCCTGCCTGGCGTCACCGCGTGCTGAGCTGA

Upstream 100 bases:

>100_bases
GCGCGCTGTTTGCGAGCGCCCGATGTCCGCCGTCGCTGTTCCATACCCGCTGTCCGCACTGCCTATGCAGGAGCCTTTCG
CAGGAGTTTTTCGAACGCTT

Downstream 100 bases:

>100_bases
AAGCGTTTGACCTGAATCGCACGCATTGAAAGTGCCGCCGCCGCTACCATGTGAGCGACGTGCACCAACCGACTACCCAG
AATCGAGCGAACTTCGCATG

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSDLNAQSAKSPSHARPFRVAALQMVSTPDRDRNLADAERLIAQAAAEGAQLVLLPEYFCFMGFKDTDKLTVREAYGDGP
VQRFLADAARRHQVWIIGGTLPLQAPEATRVLNTTLVFDPQGNEAARYDKIHLFNFEKGEESFDEARTICPGDTVRTFDA
PFGRVGLSVCYDLRFPELYRRMGDCALIVVPSAFTYTTGRAHWETLLRARAVENQCYVLAAAQGGKHENGRRTWGHSMLI
DPWGEIIDVRDEGAGVVAGNIERSRIDEVRQSLPAWRHRVLS

Sequences:

>Translated_282_residues
MSDLNAQSAKSPSHARPFRVAALQMVSTPDRDRNLADAERLIAQAAAEGAQLVLLPEYFCFMGFKDTDKLTVREAYGDGP
VQRFLADAARRHQVWIIGGTLPLQAPEATRVLNTTLVFDPQGNEAARYDKIHLFNFEKGEESFDEARTICPGDTVRTFDA
PFGRVGLSVCYDLRFPELYRRMGDCALIVVPSAFTYTTGRAHWETLLRARAVENQCYVLAAAQGGKHENGRRTWGHSMLI
DPWGEIIDVRDEGAGVVAGNIERSRIDEVRQSLPAWRHRVLS
>Mature_281_residues
SDLNAQSAKSPSHARPFRVAALQMVSTPDRDRNLADAERLIAQAAAEGAQLVLLPEYFCFMGFKDTDKLTVREAYGDGPV
QRFLADAARRHQVWIIGGTLPLQAPEATRVLNTTLVFDPQGNEAARYDKIHLFNFEKGEESFDEARTICPGDTVRTFDAP
FGRVGLSVCYDLRFPELYRRMGDCALIVVPSAFTYTTGRAHWETLLRARAVENQCYVLAAAQGGKHENGRRTWGHSMLID
PWGEIIDVRDEGAGVVAGNIERSRIDEVRQSLPAWRHRVLS

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=266, Percent_Identity=37.593984962406, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI297632348, Length=281, Percent_Identity=35.5871886120996, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI297632350, Length=267, Percent_Identity=35.9550561797753, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI5031947, Length=267, Percent_Identity=35.9550561797753, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI297632346, Length=192, Percent_Identity=31.7708333333333, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1786412, Length=183, Percent_Identity=32.2404371584699, Blast_Score=78, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17556280, Length=269, Percent_Identity=39.0334572490706, Blast_Score=197, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6323383, Length=277, Percent_Identity=33.2129963898917, Blast_Score=165, Evalue=9e-42,
Organism=Saccharomyces cerevisiae, GI6322335, Length=299, Percent_Identity=33.4448160535117, Blast_Score=156, Evalue=4e-39,
Organism=Drosophila melanogaster, GI17933642, Length=266, Percent_Identity=36.4661654135338, Blast_Score=184, Evalue=6e-47,
Organism=Drosophila melanogaster, GI21355835, Length=270, Percent_Identity=34.8148148148148, Blast_Score=166, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 31520; Mature: 31389

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLNAQSAKSPSHARPFRVAALQMVSTPDRDRNLADAERLIAQAAAEGAQLVLLPEYFC
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEECHHHH
FMGFKDTDKLTVREAYGDGPVQRFLADAARRHQVWIIGGTLPLQAPEATRVLNTTLVFDP
HCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHEEEEEEEECC
QGNEAARYDKIHLFNFEKGEESFDEARTICPGDTVRTFDAPFGRVGLSVCYDLRFPELYR
CCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCEEECCCCCHHHHHHHHEECCCHHHHH
RMGDCALIVVPSAFTYTTGRAHWETLLRARAVENQCYVLAAAQGGKHENGRRTWGHSMLI
HHCCEEEEEECCCEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCEEE
DPWGEIIDVRDEGAGVVAGNIERSRIDEVRQSLPAWRHRVLS
CCCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDLNAQSAKSPSHARPFRVAALQMVSTPDRDRNLADAERLIAQAAAEGAQLVLLPEYFC
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEECHHHH
FMGFKDTDKLTVREAYGDGPVQRFLADAARRHQVWIIGGTLPLQAPEATRVLNTTLVFDP
HCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHEEEEEEEECC
QGNEAARYDKIHLFNFEKGEESFDEARTICPGDTVRTFDAPFGRVGLSVCYDLRFPELYR
CCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCEEECCCCCHHHHHHHHEECCCHHHHH
RMGDCALIVVPSAFTYTTGRAHWETLLRARAVENQCYVLAAAQGGKHENGRRTWGHSMLI
HHCCEEEEEECCCEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCEEE
DPWGEIIDVRDEGAGVVAGNIERSRIDEVRQSLPAWRHRVLS
CCCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]