Click here to switch to the map view.

The map label for this gene is yajO [H]

Identifier: 186477109

GI number: 186477109

Start: 2647077

End: 2648072

Strand: Direct

Name: yajO [H]

Synonym: Bphy_2358

Alternate gene names: 186477109

Gene position: 2647077-2648072 (Clockwise)

Preceding gene: 186477106

Following gene: 186477111

Centisome position: 76.08

GC content: 63.55

Gene sequence:

>996_bases
ATGCAATACCGCAAATTCGGCCATACGGGCCTGACTGTCTCGCGTCTGTGTCTCGGAACGATGACGTTCGGTTTGCAAAC
TGAAGAGGATATATCGCGCGGCATTCTCGACAAGGCGACGGATGCCGGCGTGAACTTCATCGATACGGCCGACGTCTATC
CGCTCGGCGGCGGCGAAGATGTGGCAGGCCGCACCGAGGAGATCATCGGACGCTGGCTCAAAGGCAAGCGCGAGCGCTTT
ATCCTCGCGACGAAAGCCGTCGGCAAGGTGGGGCCGCATCCGTGGAATCAGGGCGCATCGCGCAAGCACCTGCTCGACGC
CATCGACGATTCATTGCGGCGCCTGAACACCGACTACGTCGACCTCTACCAGTTGCACTCCGACGACCGCGACACGCCGC
TCGACGAAACGCTCGAAGCGCTCGACGTGATCGTGCGCTCGGGCAAGGCGCGTTATATCGGCGTATCGAACTATCTCGCC
TACCGGCTCGCGCGCATGCTGGGGCGCGCGGACGTGCTGCGTACCGCGCGTTTCGTGTCGGTGCAGCCGCGCTACAACCT
GCTGTTCCGGCAGATCGAACGCGAACTGCTGCCGCTCGCCGACGAAGAAGGGCTGGCCGTGATTCCGTATAACCCGCTCG
CGGGCGGCCTGCTGACGGGCAAACATCGTCACGACGCGAAGCCCGCGGACGGGCGCTTCACCGAAGCGGTCGGCAAGGCG
GGCGCAATGTACTCGGAGCGCTATTGGCACGAGCGCGAGTTCAAGACCATCGACACGCTGCGCGACATCAACGCGAAAAC
GGGCGAGCCGATGACGAAGACAGCCATCGCATGGGTGCTCGCGAATCCGACCATCACGTCGGCGATCATCGGTGCGAGCC
GCGTCGAACAGTTGAACGACTCGCTCGCCGCCGTCGACTACGCGCTCGATCCCGAGATCAAGAAGCAGCTCGACGAAGCA
ACCGTCGAGTATCGCTGGGGCGATGCGCCGCGCTGA

Upstream 100 bases:

>100_bases
AGCGCAGCGACGCGGATCGGCAATAGCCGCTATCCTCTGTCTTCTGCGTTTCAACCGGCTGTACTCGACCACTCACCCTT
CTCTTCTCGCGGAGTCGATC

Downstream 100 bases:

>100_bases
ACTGCGGCGAAACGGAATGAGTCGGACCGCGGAAAAGTGCGTGAGACTGCAATTACCGAATTGCTGGGACTGGCCGAACT
GAAGCGCGTGTGGACAAGCC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MQYRKFGHTGLTVSRLCLGTMTFGLQTEEDISRGILDKATDAGVNFIDTADVYPLGGGEDVAGRTEEIIGRWLKGKRERF
ILATKAVGKVGPHPWNQGASRKHLLDAIDDSLRRLNTDYVDLYQLHSDDRDTPLDETLEALDVIVRSGKARYIGVSNYLA
YRLARMLGRADVLRTARFVSVQPRYNLLFRQIERELLPLADEEGLAVIPYNPLAGGLLTGKHRHDAKPADGRFTEAVGKA
GAMYSERYWHEREFKTIDTLRDINAKTGEPMTKTAIAWVLANPTITSAIIGASRVEQLNDSLAAVDYALDPEIKKQLDEA
TVEYRWGDAPR

Sequences:

>Translated_331_residues
MQYRKFGHTGLTVSRLCLGTMTFGLQTEEDISRGILDKATDAGVNFIDTADVYPLGGGEDVAGRTEEIIGRWLKGKRERF
ILATKAVGKVGPHPWNQGASRKHLLDAIDDSLRRLNTDYVDLYQLHSDDRDTPLDETLEALDVIVRSGKARYIGVSNYLA
YRLARMLGRADVLRTARFVSVQPRYNLLFRQIERELLPLADEEGLAVIPYNPLAGGLLTGKHRHDAKPADGRFTEAVGKA
GAMYSERYWHEREFKTIDTLRDINAKTGEPMTKTAIAWVLANPTITSAIIGASRVEQLNDSLAAVDYALDPEIKKQLDEA
TVEYRWGDAPR
>Mature_331_residues
MQYRKFGHTGLTVSRLCLGTMTFGLQTEEDISRGILDKATDAGVNFIDTADVYPLGGGEDVAGRTEEIIGRWLKGKRERF
ILATKAVGKVGPHPWNQGASRKHLLDAIDDSLRRLNTDYVDLYQLHSDDRDTPLDETLEALDVIVRSGKARYIGVSNYLA
YRLARMLGRADVLRTARFVSVQPRYNLLFRQIERELLPLADEEGLAVIPYNPLAGGLLTGKHRHDAKPADGRFTEAVGKA
GAMYSERYWHEREFKTIDTLRDINAKTGEPMTKTAIAWVLANPTITSAIIGASRVEQLNDSLAAVDYALDPEIKKQLDEA
TVEYRWGDAPR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=314, Percent_Identity=31.8471337579618, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI27436962, Length=314, Percent_Identity=31.5286624203822, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI27436969, Length=311, Percent_Identity=30.2250803858521, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI27436966, Length=314, Percent_Identity=31.5286624203822, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI4504825, Length=309, Percent_Identity=30.0970873786408, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI27436971, Length=335, Percent_Identity=29.8507462686567, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI223718702, Length=318, Percent_Identity=30.8176100628931, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI41152114, Length=314, Percent_Identity=30.5732484076433, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI41327764, Length=319, Percent_Identity=31.6614420062696, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI87081735, Length=328, Percent_Identity=42.9878048780488, Blast_Score=230, Evalue=9e-62,
Organism=Escherichia coli, GI1789199, Length=352, Percent_Identity=35.2272727272727, Blast_Score=185, Evalue=4e-48,
Organism=Escherichia coli, GI1789375, Length=312, Percent_Identity=35.2564102564103, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1788070, Length=349, Percent_Identity=29.512893982808, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1788081, Length=220, Percent_Identity=33.1818181818182, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI48994888, Length=302, Percent_Identity=23.1788079470199, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI212645785, Length=327, Percent_Identity=24.4648318042813, Blast_Score=71, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6325169, Length=342, Percent_Identity=30.1169590643275, Blast_Score=135, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6319958, Length=288, Percent_Identity=27.7777777777778, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6323998, Length=323, Percent_Identity=27.5541795665635, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6319951, Length=326, Percent_Identity=25.7668711656442, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6322615, Length=251, Percent_Identity=26.2948207171315, Blast_Score=92, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24646155, Length=261, Percent_Identity=33.7164750957854, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24640980, Length=326, Percent_Identity=23.3128834355828, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI45549126, Length=326, Percent_Identity=23.3128834355828, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24646159, Length=261, Percent_Identity=32.5670498084291, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36988; Mature: 36988

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00062 ALDOKETO_REDUCTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYRKFGHTGLTVSRLCLGTMTFGLQTEEDISRGILDKATDAGVNFIDTADVYPLGGGED
CCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEECCCEEECCCCCC
VAGRTEEIIGRWLKGKRERFILATKAVGKVGPHPWNQGASRKHLLDAIDDSLRRLNTDYV
CCCHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHH
DLYQLHSDDRDTPLDETLEALDVIVRSGKARYIGVSNYLAYRLARMLGRADVLRTARFVS
HHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHEE
VQPRYNLLFRQIERELLPLADEEGLAVIPYNPLAGGLLTGKHRHDAKPADGRFTEAVGKA
CCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
GAMYSERYWHEREFKTIDTLRDINAKTGEPMTKTAIAWVLANPTITSAIIGASRVEQLND
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SLAAVDYALDPEIKKQLDEATVEYRWGDAPR
HHHHHHHHCCHHHHHHHHHHHEEECCCCCCC
>Mature Secondary Structure
MQYRKFGHTGLTVSRLCLGTMTFGLQTEEDISRGILDKATDAGVNFIDTADVYPLGGGED
CCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEECCCEEECCCCCC
VAGRTEEIIGRWLKGKRERFILATKAVGKVGPHPWNQGASRKHLLDAIDDSLRRLNTDYV
CCCHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHH
DLYQLHSDDRDTPLDETLEALDVIVRSGKARYIGVSNYLAYRLARMLGRADVLRTARFVS
HHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHEE
VQPRYNLLFRQIERELLPLADEEGLAVIPYNPLAGGLLTGKHRHDAKPADGRFTEAVGKA
CCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
GAMYSERYWHEREFKTIDTLRDINAKTGEPMTKTAIAWVLANPTITSAIIGASRVEQLND
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SLAAVDYALDPEIKKQLDEATVEYRWGDAPR
HHHHHHHHCCHHHHHHHHHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]