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The map label for this gene is dprE1 [H]

Identifier: 186477023

GI number: 186477023

Start: 2546941

End: 2548263

Strand: Direct

Name: dprE1 [H]

Synonym: Bphy_2272

Alternate gene names: 186477023

Gene position: 2546941-2548263 (Clockwise)

Preceding gene: 186477022

Following gene: 186477024

Centisome position: 73.21

GC content: 65.61

Gene sequence:

>1323_bases
ATGAACGCCTCGAAGCTGCAGTCGTGGGGACGATACCCCTACGCTCACCAGTCGGGTGAACCGCTTGCCTGGCGTGATGC
CATCCAGACGCGCCTCGCCGACGCCCACGCGCGTCGTGGTACGACGCTCGCGTTCGGCAACGGCCGCAGCTACGGTGACA
GTTGCCTCGCGGATACCGGACAGGTGCTGCCCATGCGCGGCCTCGCGCGCTTCATGAGCGCGGACTGGACGAGCGGCGTC
GTGCGCGCCGAAGCGGGCATGACGCTCGGTGAACTGCTCGACGTCGCCTTGCCGCGTGGCTGGATGCTGCCCGTCACACC
CGGGACGCAGTTCGCTACGCTTGGCGGGGCCGTGGCCAACGACGTGCACGGCAAGAACCATCATGTGCGCGGCACCTTCG
GACGCCACGTGCGCTGCTTTTCGCTGCTGCGCTCCGACCGTCCAGCCACCGAATGTTCACCGGATGAGGAAGCCGCGCTC
TTTCGTGCGACGATCGGCGGGCTCGGCCTGACGGGTGTGATCGAATGGGTAGAACTCCAGCTCATGCCGGTACGCTCGGC
CCATATTGCCGTCTCACGCATACGCTACGCCAACCTCGACGAATTCTTCGCGCTCGCGCAAGACCACGAGGCCATCCATG
AGTACGGGGTCGCGTGGGTGGACTGCCTCGCGCGCGGCGGGGCGCTCGGGCGCGGCATCTACACTAGCGGCGATCACGCC
GACGACGGTGACTTCTCTATCTCGACGAAGCGCGCCTGCAGTGTACCGTTCGTCCCGCCGTTCTCGCCCGTCAGCCGAAC
CACGGTGCGCGCATTCAACGCGCTCTATTACTGGCGTCAGAAGCCCGGCATCGAACTCGCGCGCATGACCCCGGCCAGTT
TCTTCTATCCACTCGACAACATCCTCAACTGGAATCGCCTCTATGGGCGACGCGGGTTCCAGCAGCATCAATGCGTCGTG
CCGACGGCGAGCGCGCGCGACGCGCTGCGGGCAATCCTGGATACCATCGCCACGCACGGCAGCGGCTCATTTCTCGCGGT
GCTCAAGCGTTGTGGCTCCCTGCCCTCACCTGGCCTGCTCTCGTTTCCGATGGAAGGCGTCTCGCTCGCGCTCGACTTCC
CGCAGAACGAACGGCGCAACACCGACCTCTTCGCCCGGCTCGATTCCATCGTGGCCGAATCCGGCGGTCGTCAGTATCCC
GCGAAAGATGCACACATGAGCGGGGAGCACTTCCGCGCGGCTTACCCCGCGTGGCAGGAACTCGAGCGGCATCGCGATCC
CGCGCTGATGTCGCGTTTCTGGAAACGGACGACTCAATCATGA

Upstream 100 bases:

>100_bases
GCAACGGCATCCGCCCGTCGCTTCGAACTGTGGTGTGGCCCACTGTCGGCGGCCCGATCTTCTGCCAAATTGCGAGACAT
TCGAAATGGTCTCGTCATAC

Downstream 100 bases:

>100_bases
AGAACATCCTTGTCATTGGCGGCTCGTCAGCCATCGCCGCCGCTTGCGCACGGCACTGGGCCGCAGACGGCGACCGCCTG
TTCCTCGCTGGCCGTCATGC

Product: FAD linked oxidase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MNASKLQSWGRYPYAHQSGEPLAWRDAIQTRLADAHARRGTTLAFGNGRSYGDSCLADTGQVLPMRGLARFMSADWTSGV
VRAEAGMTLGELLDVALPRGWMLPVTPGTQFATLGGAVANDVHGKNHHVRGTFGRHVRCFSLLRSDRPATECSPDEEAAL
FRATIGGLGLTGVIEWVELQLMPVRSAHIAVSRIRYANLDEFFALAQDHEAIHEYGVAWVDCLARGGALGRGIYTSGDHA
DDGDFSISTKRACSVPFVPPFSPVSRTTVRAFNALYYWRQKPGIELARMTPASFFYPLDNILNWNRLYGRRGFQQHQCVV
PTASARDALRAILDTIATHGSGSFLAVLKRCGSLPSPGLLSFPMEGVSLALDFPQNERRNTDLFARLDSIVAESGGRQYP
AKDAHMSGEHFRAAYPAWQELERHRDPALMSRFWKRTTQS

Sequences:

>Translated_440_residues
MNASKLQSWGRYPYAHQSGEPLAWRDAIQTRLADAHARRGTTLAFGNGRSYGDSCLADTGQVLPMRGLARFMSADWTSGV
VRAEAGMTLGELLDVALPRGWMLPVTPGTQFATLGGAVANDVHGKNHHVRGTFGRHVRCFSLLRSDRPATECSPDEEAAL
FRATIGGLGLTGVIEWVELQLMPVRSAHIAVSRIRYANLDEFFALAQDHEAIHEYGVAWVDCLARGGALGRGIYTSGDHA
DDGDFSISTKRACSVPFVPPFSPVSRTTVRAFNALYYWRQKPGIELARMTPASFFYPLDNILNWNRLYGRRGFQQHQCVV
PTASARDALRAILDTIATHGSGSFLAVLKRCGSLPSPGLLSFPMEGVSLALDFPQNERRNTDLFARLDSIVAESGGRQYP
AKDAHMSGEHFRAAYPAWQELERHRDPALMSRFWKRTTQS
>Mature_440_residues
MNASKLQSWGRYPYAHQSGEPLAWRDAIQTRLADAHARRGTTLAFGNGRSYGDSCLADTGQVLPMRGLARFMSADWTSGV
VRAEAGMTLGELLDVALPRGWMLPVTPGTQFATLGGAVANDVHGKNHHVRGTFGRHVRCFSLLRSDRPATECSPDEEAAL
FRATIGGLGLTGVIEWVELQLMPVRSAHIAVSRIRYANLDEFFALAQDHEAIHEYGVAWVDCLARGGALGRGIYTSGDHA
DDGDFSISTKRACSVPFVPPFSPVSRTTVRAFNALYYWRQKPGIELARMTPASFFYPLDNILNWNRLYGRRGFQQHQCVV
PTASARDALRAILDTIATHGSGSFLAVLKRCGSLPSPGLLSFPMEGVSLALDFPQNERRNTDLFARLDSIVAESGGRQYP
AKDAHMSGEHFRAAYPAWQELERHRDPALMSRFWKRTTQS

Specific function: Involved in the epimerization of decaprenylphosphoryl ribose (DPR) to decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Probably catalyzes the oxidation at C-2 of decaprenylphosphoryl ribose (

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007173
- InterPro:   IPR016166
- InterPro:   IPR016168
- InterPro:   IPR006094 [H]

Pfam domain/function: PF04030 ALO; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 48551; Mature: 48551

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASKLQSWGRYPYAHQSGEPLAWRDAIQTRLADAHARRGTTLAFGNGRSYGDSCLADTG
CCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHCCC
QVLPMRGLARFMSADWTSGVVRAEAGMTLGELLDVALPRGWMLPVTPGTQFATLGGAVAN
CCCCHHHHHHHHHCCCCCCEEEHHCCCCHHHHHHHHCCCCCEEECCCCCCHHHHCCHHHH
DVHGKNHHVRGTFGRHVRCFSLLRSDRPATECSPDEEAALFRATIGGLGLTGVIEWVELQ
CCCCCCCEECCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHE
LMPVRSAHIAVSRIRYANLDEFFALAQDHEAIHEYGVAWVDCLARGGALGRGIYTSGDHA
EEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
DDGDFSISTKRACSVPFVPPFSPVSRTTVRAFNALYYWRQKPGIELARMTPASFFYPLDN
CCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHCCHHH
ILNWNRLYGRRGFQQHQCVVPTASARDALRAILDTIATHGSGSFLAVLKRCGSLPSPGLL
HHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCE
SFPMEGVSLALDFPQNERRNTDLFARLDSIVAESGGRQYPAKDAHMSGEHFRAAYPAWQE
ECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCHHHHH
LERHRDPALMSRFWKRTTQS
HHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MNASKLQSWGRYPYAHQSGEPLAWRDAIQTRLADAHARRGTTLAFGNGRSYGDSCLADTG
CCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHCCC
QVLPMRGLARFMSADWTSGVVRAEAGMTLGELLDVALPRGWMLPVTPGTQFATLGGAVAN
CCCCHHHHHHHHHCCCCCCEEEHHCCCCHHHHHHHHCCCCCEEECCCCCCHHHHCCHHHH
DVHGKNHHVRGTFGRHVRCFSLLRSDRPATECSPDEEAALFRATIGGLGLTGVIEWVELQ
CCCCCCCEECCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHE
LMPVRSAHIAVSRIRYANLDEFFALAQDHEAIHEYGVAWVDCLARGGALGRGIYTSGDHA
EEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
DDGDFSISTKRACSVPFVPPFSPVSRTTVRAFNALYYWRQKPGIELARMTPASFFYPLDN
CCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHCCHHH
ILNWNRLYGRRGFQQHQCVVPTASARDALRAILDTIATHGSGSFLAVLKRCGSLPSPGLL
HHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCE
SFPMEGVSLALDFPQNERRNTDLFARLDSIVAESGGRQYPAKDAHMSGEHFRAAYPAWQE
ECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCHHHHH
LERHRDPALMSRFWKRTTQS
HHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]