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The map label for this gene is galE [H]

Identifier: 186477022

GI number: 186477022

Start: 2545459

End: 2546481

Strand: Direct

Name: galE [H]

Synonym: Bphy_2271

Alternate gene names: 186477022

Gene position: 2545459-2546481 (Clockwise)

Preceding gene: 186477021

Following gene: 186477023

Centisome position: 73.16

GC content: 63.25

Gene sequence:

>1023_bases
ATGACCACGAAGGGCACGATTCTGGTAACGGGCGGTGCAGGCTTCATCGGTTCGCACACGTGCGTGGAACTGCTCAACAG
CGATTACGACGTGGTCGTGATCGACAACCTCGTGAACAGCAAGCGCGAATCGATGGCGCGCGTCGAGCAGATCACGGGCA
AGCAGGTGGCGTTCTACGAAGCCAACGTGCGCGACGAGACCGTGCTGAACACGATTTTCGACAGACATCCCATCACGGGT
GCGATTCACTTCGCCGCGCTGAAGGCCGTGGGCGAATCGGTCGCGAAGCCGCTCGAGTATTACCGCAACAACATGGATGG
CCTGCTCGCGCTGCTCGACGTGATGCGCGCACGCAATGTGAAGCAGTTCGTGTTCAGCTCCTCCGCGACCGTGTATGGCG
TGCCGAAGAGCTCGCCCATCGACGAAACCTTCCCGCTCTCGGCCACCAACCCGTACGGCCAGAGCAAGTTGATCGCCGAG
CAGATCCTGCGCGATCTCGAAATCTCCGATCCGTCGTGGCGCATCGCGACGCTGCGCTACTTCAACCCGGTGGGTGCGCA
CGAAAGCGGCCTGATCGGCGAAGATCCGGGCGGCGTGCCGAACAACCTGATGCCGTATGTCGCGCAGGTTGCTGTCGGCA
AGCTCGAACGGCTGCGCGTGTTCGGCGGCGATTACGACACACCGGATGGCACGGGCGTGCGCGATTACATCCACGTCGTC
GATCTGGCGCGCGGACATATCGCGGCGCTCGATGCCCTCGTCGAGCGCGACGCGAGCTTCGTCGTCAATCTCGGTACGGG
CCAGGGCTACAGCGTGCTCGACGTCGTGAAGGCGTTCGAGAAAGCGTCGGGCAAGCCTGTGCCGTACGAGATCGTCGCGC
GCCGCCCCGGCGATGTCGCGCAATGCTTCGCAAACCCCGCGAAGGCGCTCGAAGTGATCGGCTGGCAAGCGCAGTACGGC
ATCGAACGCATGTGTGCGGACCACTGGCGCTGGCAGGCGCAGAATCCGCGCGGCTTCGAATAA

Upstream 100 bases:

>100_bases
GGGCCAAGGTCACGCGTGAATTCGACGAACGCGGTGTCGTCGAACGGTACAAGAGCCTGATTCAGCAGTTGACGGGCATA
TCACTCTAAGGGAGCTCAGG

Downstream 100 bases:

>100_bases
AACGTCGTTCCGGGGGATACTCGCCATCGCGCCCGTTTCCTCCGCCTGCCTCCGTTCCGTGCAGCCCGCGCCGATCCGGC
GATTGCAGCGCGAGTGCCGT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTTKGTILVTGGAGFIGSHTCVELLNSDYDVVVIDNLVNSKRESMARVEQITGKQVAFYEANVRDETVLNTIFDRHPITG
AIHFAALKAVGESVAKPLEYYRNNMDGLLALLDVMRARNVKQFVFSSSATVYGVPKSSPIDETFPLSATNPYGQSKLIAE
QILRDLEISDPSWRIATLRYFNPVGAHESGLIGEDPGGVPNNLMPYVAQVAVGKLERLRVFGGDYDTPDGTGVRDYIHVV
DLARGHIAALDALVERDASFVVNLGTGQGYSVLDVVKAFEKASGKPVPYEIVARRPGDVAQCFANPAKALEVIGWQAQYG
IERMCADHWRWQAQNPRGFE

Sequences:

>Translated_340_residues
MTTKGTILVTGGAGFIGSHTCVELLNSDYDVVVIDNLVNSKRESMARVEQITGKQVAFYEANVRDETVLNTIFDRHPITG
AIHFAALKAVGESVAKPLEYYRNNMDGLLALLDVMRARNVKQFVFSSSATVYGVPKSSPIDETFPLSATNPYGQSKLIAE
QILRDLEISDPSWRIATLRYFNPVGAHESGLIGEDPGGVPNNLMPYVAQVAVGKLERLRVFGGDYDTPDGTGVRDYIHVV
DLARGHIAALDALVERDASFVVNLGTGQGYSVLDVVKAFEKASGKPVPYEIVARRPGDVAQCFANPAKALEVIGWQAQYG
IERMCADHWRWQAQNPRGFE
>Mature_339_residues
TTKGTILVTGGAGFIGSHTCVELLNSDYDVVVIDNLVNSKRESMARVEQITGKQVAFYEANVRDETVLNTIFDRHPITGA
IHFAALKAVGESVAKPLEYYRNNMDGLLALLDVMRARNVKQFVFSSSATVYGVPKSSPIDETFPLSATNPYGQSKLIAEQ
ILRDLEISDPSWRIATLRYFNPVGAHESGLIGEDPGGVPNNLMPYVAQVAVGKLERLRVFGGDYDTPDGTGVRDYIHVVD
LARGHIAALDALVERDASFVVNLGTGQGYSVLDVVKAFEKASGKPVPYEIVARRPGDVAQCFANPAKALEVIGWQAQYGI
ERMCADHWRWQAQNPRGFE

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=59.1176470588235, Blast_Score=419, Evalue=1e-117,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=59.1176470588235, Blast_Score=419, Evalue=1e-117,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=59.1176470588235, Blast_Score=419, Evalue=1e-117,
Organism=Homo sapiens, GI7657641, Length=274, Percent_Identity=27.007299270073, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1786974, Length=334, Percent_Identity=54.4910179640719, Blast_Score=384, Evalue=1e-108,
Organism=Escherichia coli, GI1788353, Length=362, Percent_Identity=27.3480662983425, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI48994969, Length=355, Percent_Identity=27.3239436619718, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71982035, Length=343, Percent_Identity=55.9766763848396, Blast_Score=382, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI71982038, Length=345, Percent_Identity=55.6521739130435, Blast_Score=380, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6319493, Length=348, Percent_Identity=52.5862068965517, Blast_Score=365, Evalue=1e-102,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=56.5597667638484, Blast_Score=400, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37205; Mature: 37073

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKGTILVTGGAGFIGSHTCVELLNSDYDVVVIDNLVNSKRESMARVEQITGKQVAFYE
CCCCCEEEEECCCCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEEE
ANVRDETVLNTIFDRHPITGAIHFAALKAVGESVAKPLEYYRNNMDGLLALLDVMRARNV
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCH
KQFVFSSSATVYGVPKSSPIDETFPLSATNPYGQSKLIAEQILRDLEISDPSWRIATLRY
HHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEE
FNPVGAHESGLIGEDPGGVPNNLMPYVAQVAVGKLERLRVFGGDYDTPDGTGVRDYIHVV
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHH
DLARGHIAALDALVERDASFVVNLGTGQGYSVLDVVKAFEKASGKPVPYEIVARRPGDVA
HHHCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCHHEEECCCCHHH
QCFANPAKALEVIGWQAQYGIERMCADHWRWQAQNPRGFE
HHHCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TTKGTILVTGGAGFIGSHTCVELLNSDYDVVVIDNLVNSKRESMARVEQITGKQVAFYE
CCCCEEEEECCCCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEEE
ANVRDETVLNTIFDRHPITGAIHFAALKAVGESVAKPLEYYRNNMDGLLALLDVMRARNV
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCH
KQFVFSSSATVYGVPKSSPIDETFPLSATNPYGQSKLIAEQILRDLEISDPSWRIATLRY
HHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEE
FNPVGAHESGLIGEDPGGVPNNLMPYVAQVAVGKLERLRVFGGDYDTPDGTGVRDYIHVV
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHH
DLARGHIAALDALVERDASFVVNLGTGQGYSVLDVVKAFEKASGKPVPYEIVARRPGDVA
HHHCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCHHEEECCCCHHH
QCFANPAKALEVIGWQAQYGIERMCADHWRWQAQNPRGFE
HHHCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]