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The map label for this gene is cobT [H]

Identifier: 186476961

GI number: 186476961

Start: 2483617

End: 2484699

Strand: Reverse

Name: cobT [H]

Synonym: Bphy_2210

Alternate gene names: 186476961

Gene position: 2484699-2483617 (Counterclockwise)

Preceding gene: 186476962

Following gene: 186476960

Centisome position: 71.42

GC content: 66.2

Gene sequence:

>1083_bases
ATGAACCGAACCATTCAAGCAGATACCCACATGACCACTTCGCATTCCCTGCCTCACGTCGCGCCGCTCGAACCGTCGCT
GCGCGCCGATTTGCAACGCATCATCGACCTGAAGACCAAGCCGCCCGGCAGCCTCGGCCAGCTCGAAACGCTCGCGCGTC
AGATGGGCATGATCCAGCGGACGACGCAGCCGACCATCGTGCGTCCCGCGATGATCGTGTTCGCCGCCGATCACGGCATT
GCGAACGCGGGCGTCAGTCCGTATCCGCAGGCGGTGACGGCGCAGATGGTGCTCAACTTTCTCGCGGGCGGCGCGGCGAT
CAATGCGTTCAGCCGCGTCGCGGGCCTCGAACTCGAAGTGGTGAATGCAGGCGTCGCGCACACGTTCGAACCGCACGAAA
GACTCGTCGACATTCCGCTGGGCAAGGGCACGCGCAACTTCGCGCAAGAGCCTGCGATGACGCGTGACGAAGCGCTCGCC
GCGATGCATGCGGGCGCCGAACGTGTGCGTTGTCACGCGGCGCTCGGTACCAACGTGATCGGCTTCGGCGAGATGGGCAT
TGCGAATACGTCGTCGGCTGCATGCCTGATGAGCCGCCTGTGCGGTGCGCCCATCGACGATTGCGTCGGGCGGGGCACGG
GGCTGGACAACGCGGGCCTCGTGAAGAAGCGCAATGTGCTGGCGGCGGCGCTTGCCCATCATCCCGTGTCGGACGATCCA
CTCGATGTGCTCGCAACCTTCGGCGGCTTCGAGATCGCGATGATGGCGGGCGCGTATCTCGCGGCGGCGGAAGCACGCAT
GACGATCGTCGTCGACGGTTTCATCGCCACTTCCGCGCTGCTGGTCGCCGATGCGTTCGCACCCGCCGTGCGCGATTACT
GCGTGTTCGCGCACGCATCGCACGAGGCGGGGCATCGGCGCATGCTCGATTATTTCGGCGCGGTGCCGCTGCTCGCGCTC
GATCTGCGCCTTGGCGAAGGCACGGGCGCCGCGCTTGCCATGCCGCTGCTGCGCGCGGCCGTCGCGTTCATCAACGAGAT
GGCGAGCTTCGAGTCGGCAGGCGTCGCGCAACGCGATGCATGA

Upstream 100 bases:

>100_bases
GGCCAGTCGCGCATTCGGCTATCCGCTCGTGCTGATACGCGACGGCGACGACGAAGCGCTGATTCCCGCATTGCGCACAC
CGGCGCGCCCCTGAACACAC

Downstream 100 bases:

>100_bases
TGCTTGCCGGGCGCATCGAAACAGGCGGTGAAACGACTGCGATGAGTCAATCACGATGAATGAGCTGCGTTACTTTTTCA
CGGCGCTCGGCTACTTCACG

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MNRTIQADTHMTTSHSLPHVAPLEPSLRADLQRIIDLKTKPPGSLGQLETLARQMGMIQRTTQPTIVRPAMIVFAADHGI
ANAGVSPYPQAVTAQMVLNFLAGGAAINAFSRVAGLELEVVNAGVAHTFEPHERLVDIPLGKGTRNFAQEPAMTRDEALA
AMHAGAERVRCHAALGTNVIGFGEMGIANTSSAACLMSRLCGAPIDDCVGRGTGLDNAGLVKKRNVLAAALAHHPVSDDP
LDVLATFGGFEIAMMAGAYLAAAEARMTIVVDGFIATSALLVADAFAPAVRDYCVFAHASHEAGHRRMLDYFGAVPLLAL
DLRLGEGTGAALAMPLLRAAVAFINEMASFESAGVAQRDA

Sequences:

>Translated_360_residues
MNRTIQADTHMTTSHSLPHVAPLEPSLRADLQRIIDLKTKPPGSLGQLETLARQMGMIQRTTQPTIVRPAMIVFAADHGI
ANAGVSPYPQAVTAQMVLNFLAGGAAINAFSRVAGLELEVVNAGVAHTFEPHERLVDIPLGKGTRNFAQEPAMTRDEALA
AMHAGAERVRCHAALGTNVIGFGEMGIANTSSAACLMSRLCGAPIDDCVGRGTGLDNAGLVKKRNVLAAALAHHPVSDDP
LDVLATFGGFEIAMMAGAYLAAAEARMTIVVDGFIATSALLVADAFAPAVRDYCVFAHASHEAGHRRMLDYFGAVPLLAL
DLRLGEGTGAALAMPLLRAAVAFINEMASFESAGVAQRDA
>Mature_360_residues
MNRTIQADTHMTTSHSLPHVAPLEPSLRADLQRIIDLKTKPPGSLGQLETLARQMGMIQRTTQPTIVRPAMIVFAADHGI
ANAGVSPYPQAVTAQMVLNFLAGGAAINAFSRVAGLELEVVNAGVAHTFEPHERLVDIPLGKGTRNFAQEPAMTRDEALA
AMHAGAERVRCHAALGTNVIGFGEMGIANTSSAACLMSRLCGAPIDDCVGRGTGLDNAGLVKKRNVLAAALAHHPVSDDP
LDVLATFGGFEIAMMAGAYLAAAEARMTIVVDGFIATSALLVADAFAPAVRDYCVFAHASHEAGHRRMLDYFGAVPLLAL
DLRLGEGTGAALAMPLLRAAVAFINEMASFESAGVAQRDA

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=326, Percent_Identity=36.1963190184049, Blast_Score=191, Evalue=8e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 37720; Mature: 37720

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRTIQADTHMTTSHSLPHVAPLEPSLRADLQRIIDLKTKPPGSLGQLETLARQMGMIQR
CCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
TTQPTIVRPAMIVFAADHGIANAGVSPYPQAVTAQMVLNFLAGGAAINAFSRVAGLELEV
CCCCCEECCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEE
VNAGVAHTFEPHERLVDIPLGKGTRNFAQEPAMTRDEALAAMHAGAERVRCHAALGTNVI
ECCCCCCCCCHHHHEEECCCCCCCHHHHHCCCCCHHHHHHHHHCCHHHHEEHHHHCCCEE
GFGEMGIANTSSAACLMSRLCGAPIDDCVGRGTGLDNAGLVKKRNVLAAALAHHPVSDDP
ECCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCH
LDVLATFGGFEIAMMAGAYLAAAEARMTIVVDGFIATSALLVADAFAPAVRDYCVFAHAS
HHHHHHCCCHHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHEEECC
HEAGHRRMLDYFGAVPLLALDLRLGEGTGAALAMPLLRAAVAFINEMASFESAGVAQRDA
CHHHHHHHHHHHCCHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNRTIQADTHMTTSHSLPHVAPLEPSLRADLQRIIDLKTKPPGSLGQLETLARQMGMIQR
CCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
TTQPTIVRPAMIVFAADHGIANAGVSPYPQAVTAQMVLNFLAGGAAINAFSRVAGLELEV
CCCCCEECCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEE
VNAGVAHTFEPHERLVDIPLGKGTRNFAQEPAMTRDEALAAMHAGAERVRCHAALGTNVI
ECCCCCCCCCHHHHEEECCCCCCCHHHHHCCCCCHHHHHHHHHCCHHHHEEHHHHCCCEE
GFGEMGIANTSSAACLMSRLCGAPIDDCVGRGTGLDNAGLVKKRNVLAAALAHHPVSDDP
ECCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCH
LDVLATFGGFEIAMMAGAYLAAAEARMTIVVDGFIATSALLVADAFAPAVRDYCVFAHAS
HHHHHHCCCHHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHEEECC
HEAGHRRMLDYFGAVPLLALDLRLGEGTGAALAMPLLRAAVAFINEMASFESAGVAQRDA
CHHHHHHHHHHHCCHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA